SG76479A1 - Pleuromutilin derivatives - Google Patents
Pleuromutilin derivativesInfo
- Publication number
- SG76479A1 SG76479A1 SG1996009469A SG1996009469A SG76479A1 SG 76479 A1 SG76479 A1 SG 76479A1 SG 1996009469 A SG1996009469 A SG 1996009469A SG 1996009469 A SG1996009469 A SG 1996009469A SG 76479 A1 SG76479 A1 SG 76479A1
- Authority
- SG
- Singapore
- Prior art keywords
- pct
- sec
- independently hydrogen
- date
- pleuromutilin derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/76—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members
- C07C2603/80—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings
- C07C2603/82—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings having three condensed rings with in total fourteen carbon atoms and having a having a [5.4.3.0(1,8)] ring structure, e.g. pleuromutiline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0089792A AT397654B (de) | 1992-05-04 | 1992-05-04 | Neue pleuromutilinderivate, ihre verwendung und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
SG76479A1 true SG76479A1 (en) | 2000-11-21 |
Family
ID=3502346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG1996009469A SG76479A1 (en) | 1992-05-04 | 1993-04-29 | Pleuromutilin derivatives |
Country Status (9)
Country | Link |
---|---|
US (1) | US5545654A (fr) |
EP (1) | EP0592643B1 (fr) |
JP (1) | JP2718829B2 (fr) |
AT (2) | AT397654B (fr) |
CA (1) | CA2103072C (fr) |
DE (1) | DE69326302T2 (fr) |
ES (1) | ES2138623T3 (fr) |
SG (1) | SG76479A1 (fr) |
WO (1) | WO1993022288A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY25225A1 (es) | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
GB0218578D0 (en) * | 2002-08-09 | 2002-09-18 | Glaxo Group Ltd | Novel method |
US6988990B2 (en) * | 2003-05-29 | 2006-01-24 | General Electric Company | Automatic annotation filler system and method for use in ultrasound imaging |
WO2005023257A1 (fr) * | 2003-09-03 | 2005-03-17 | Glaxo Group Limited | Procede, sels, compositions et utilisation |
EP1686115A1 (fr) * | 2005-01-26 | 2006-08-02 | Novartis AG | Sels d'acides organiques de Valnemulin |
CN101456833B (zh) * | 2008-12-12 | 2012-10-03 | 湖北龙翔药业有限公司 | 一种纯化截短侧耳素类化合物盐酸盐的方法 |
CN101597248B (zh) * | 2009-07-10 | 2012-08-22 | 河北远征药业有限公司 | 沃尼妙林及其盐酸盐的制备方法 |
CN102070499A (zh) * | 2010-12-01 | 2011-05-25 | 安徽省皖北药业股份有限公司 | 一种延胡索酸泰妙菌素的精制方法 |
CN102344397B (zh) * | 2011-08-23 | 2013-09-04 | 浙江升华拜克生物股份有限公司 | 一种伐奈莫林盐酸盐的提纯方法 |
CN102424660B (zh) * | 2011-08-25 | 2013-11-27 | 浙江升华拜克生物股份有限公司 | 一种伐奈莫林盐酸盐的低温起泡干燥法及其干燥品 |
CN103288694B (zh) * | 2013-06-28 | 2015-06-17 | 宁夏泰瑞制药股份有限公司 | 一种截短侧耳素类合成衍生物盐的晶体制备方法 |
CN104311509A (zh) * | 2014-09-15 | 2015-01-28 | 中国农业科学院兰州畜牧与兽药研究所 | 截短侧耳素类衍生物及其制备方法、应用 |
CN106496085B (zh) * | 2016-09-21 | 2018-01-26 | 盐城市舜宝化工有限公司 | 合成盐酸沃尼妙林的中间体化合物以及盐酸沃尼妙林的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0013768B1 (fr) * | 1979-01-12 | 1984-02-01 | Sandoz Ag | Pleuromutilines, leur préparation et des compositions pharmaceutiques les contenant |
EP0153277B1 (fr) * | 1984-02-17 | 1987-08-26 | Sandoz Ag | Dérivés de pleuromutiline, leur procédé de préparation et leur application |
HU208115B (en) * | 1989-10-03 | 1993-08-30 | Biochemie Gmbh | New process for producting pleuromutilin derivatives |
-
1992
- 1992-05-04 AT AT0089792A patent/AT397654B/de not_active IP Right Cessation
-
1993
- 1993-04-29 ES ES93909858T patent/ES2138623T3/es not_active Expired - Lifetime
- 1993-04-29 SG SG1996009469A patent/SG76479A1/en unknown
- 1993-04-29 US US08/178,317 patent/US5545654A/en not_active Expired - Lifetime
- 1993-04-29 AT AT93909858T patent/ATE184277T1/de active
- 1993-04-29 JP JP5518915A patent/JP2718829B2/ja not_active Expired - Lifetime
- 1993-04-29 WO PCT/EP1993/001033 patent/WO1993022288A1/fr active IP Right Grant
- 1993-04-29 CA CA002103072A patent/CA2103072C/fr not_active Expired - Fee Related
- 1993-04-29 EP EP93909858A patent/EP0592643B1/fr not_active Expired - Lifetime
- 1993-04-29 DE DE69326302T patent/DE69326302T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH06508853A (ja) | 1994-10-06 |
ES2138623T3 (es) | 2000-01-16 |
US5545654A (en) | 1996-08-13 |
EP0592643A1 (fr) | 1994-04-20 |
DE69326302D1 (de) | 1999-10-14 |
ATA89792A (de) | 1993-10-15 |
DE69326302T2 (de) | 2000-01-27 |
EP0592643B1 (fr) | 1999-09-08 |
CA2103072C (fr) | 2004-07-27 |
AT397654B (de) | 1994-06-27 |
JP2718829B2 (ja) | 1998-02-25 |
CA2103072A1 (fr) | 1993-11-05 |
WO1993022288A1 (fr) | 1993-11-11 |
ATE184277T1 (de) | 1999-09-15 |
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