SG59979A1 - Antimicrobial 5-hydrazino-quinolone derivatives - Google Patents
Antimicrobial 5-hydrazino-quinolone derivativesInfo
- Publication number
- SG59979A1 SG59979A1 SG1996007851A SG1996007851A SG59979A1 SG 59979 A1 SG59979 A1 SG 59979A1 SG 1996007851 A SG1996007851 A SG 1996007851A SG 1996007851 A SG1996007851 A SG 1996007851A SG 59979 A1 SG59979 A1 SG 59979A1
- Authority
- SG
- Singapore
- Prior art keywords
- hydrazino
- antimicrobial
- quinolone derivatives
- quinolone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96896092A | 1992-10-30 | 1992-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG59979A1 true SG59979A1 (en) | 1999-02-22 |
Family
ID=25514997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1996007851A SG59979A1 (en) | 1992-10-30 | 1993-10-22 | Antimicrobial 5-hydrazino-quinolone derivatives |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0666853A1 (ko) |
| JP (1) | JPH08502750A (ko) |
| KR (1) | KR950704301A (ko) |
| CN (1) | CN1064357C (ko) |
| AU (1) | AU687018B2 (ko) |
| BR (1) | BR9307347A (ko) |
| CA (1) | CA2148003A1 (ko) |
| CZ (1) | CZ282581B6 (ko) |
| EG (1) | EG20543A (ko) |
| FI (1) | FI952049A (ko) |
| HU (1) | HUT72072A (ko) |
| IL (1) | IL107323A (ko) |
| MX (1) | MX9306814A (ko) |
| NO (1) | NO951640L (ko) |
| NZ (1) | NZ257470A (ko) |
| PL (1) | PL178094B1 (ko) |
| RU (1) | RU2126000C1 (ko) |
| SG (1) | SG59979A1 (ko) |
| SK (1) | SK54795A3 (ko) |
| WO (1) | WO1994010163A1 (ko) |
| ZA (1) | ZA938089B (ko) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| KR100242355B1 (ko) * | 1994-08-02 | 2000-03-02 | 데이비드 엠 모이어 | 항미생물 화합물의 제조 방법 |
| KR100239200B1 (ko) * | 1994-08-02 | 2000-03-02 | 데이비드 엠 모이어 | 퀴놀로닐 락탐 항생제의 제조 방법 및 신규 중간체 화합물 |
| IL124944A (en) * | 1996-02-09 | 2003-06-24 | Toyama Chemical Co Ltd | Quinolonecarboxylic acid derivatives or their salts and pharmaceutical compositions containing them |
| KR101488403B1 (ko) * | 2005-05-18 | 2015-02-04 | 엠펙스 파마슈티컬즈, 인코포레이티드 | 에어로졸화된 플루오로퀴놀론 및 이의 용도 |
| US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| CA2528849C (en) | 2005-06-08 | 2014-01-14 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
| EA010601B1 (ru) * | 2005-06-09 | 2008-10-30 | Янссен Фармацевтика Н.В. | Производные хинолина в качестве антибактериальных агентов |
| CN101020647B (zh) * | 2007-02-14 | 2011-03-30 | 杭州师范学院 | 一种β-环丙胺基丙烯酸(酯)的合成方法 |
| EP2150544B1 (en) * | 2007-03-19 | 2016-01-13 | Takeda Pharmaceutical Company Limited | Mapk/erk kinase inhibitors |
| ES2582662T3 (es) * | 2007-10-05 | 2016-09-14 | Senhwa Biosciences, Inc. | Análogos de quinolona y procedimientos relacionados con los mismos |
| AU2009254738B2 (en) * | 2008-06-03 | 2014-05-08 | Idorsia Pharmaceuticals Ltd | [4-(1-amino-ethyl) -cyclohexyl] -methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl] -methyl-amine derivatives as antibacterials |
| HUE038428T2 (hu) | 2008-10-07 | 2018-10-29 | Horizon Orphan Llc | Aeroszol fluorokinolon készítmények javított farmakokinetika érdekében |
| WO2010042549A1 (en) | 2008-10-07 | 2010-04-15 | Mpex Pharmaceuticals, Inc. | Inhalation of levofloxacin for reducing lung inflammation |
| AR076222A1 (es) * | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen |
| PT2473170T (pt) | 2009-09-04 | 2019-08-23 | Horizon Orphan Llc | Utilização de levofloxacina em aerossol para tratamento de fibrose cística |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668680A (en) * | 1985-12-12 | 1987-05-26 | Warner-Lambert Company | 5-amino-6,8-difluoroquinolones as antibacterial agents |
| JPH0228178A (ja) * | 1988-04-23 | 1990-01-30 | Toyama Chem Co Ltd | 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法 |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| PL166381B1 (pl) * | 1989-08-16 | 1995-05-31 | Pfizer | Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL |
| EP0525057B1 (en) * | 1990-04-18 | 2000-06-14 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactams |
| DE69131428T2 (de) * | 1990-11-30 | 2000-01-05 | Warner-Lambert Co., Ann Arbor | Individuelle stereoisomere von 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolone und naphthyridone als antibakterielle wirkstoffe |
-
1993
- 1993-01-30 EG EG68693A patent/EG20543A/xx active
- 1993-10-19 IL IL10732393A patent/IL107323A/xx not_active IP Right Cessation
- 1993-10-22 PL PL93308671A patent/PL178094B1/pl unknown
- 1993-10-22 CA CA002148003A patent/CA2148003A1/en not_active Abandoned
- 1993-10-22 KR KR1019950701690A patent/KR950704301A/ko active IP Right Grant
- 1993-10-22 EP EP93924393A patent/EP0666853A1/en not_active Withdrawn
- 1993-10-22 CZ CZ951097A patent/CZ282581B6/cs not_active IP Right Cessation
- 1993-10-22 WO PCT/US1993/010091 patent/WO1994010163A1/en not_active Application Discontinuation
- 1993-10-22 AU AU54097/94A patent/AU687018B2/en not_active Ceased
- 1993-10-22 NZ NZ257470A patent/NZ257470A/xx unknown
- 1993-10-22 HU HU9501237A patent/HUT72072A/hu unknown
- 1993-10-22 JP JP6511167A patent/JPH08502750A/ja active Pending
- 1993-10-22 BR BR9307347A patent/BR9307347A/pt not_active Application Discontinuation
- 1993-10-22 RU RU95110762A patent/RU2126000C1/ru active
- 1993-10-22 SK SK547-95A patent/SK54795A3/sk unknown
- 1993-10-22 SG SG1996007851A patent/SG59979A1/en unknown
- 1993-10-29 MX MX9306814A patent/MX9306814A/es not_active IP Right Cessation
- 1993-10-29 ZA ZA938089A patent/ZA938089B/xx unknown
- 1993-10-30 CN CN93120224A patent/CN1064357C/zh not_active Expired - Fee Related
-
1995
- 1995-04-28 NO NO951640A patent/NO951640L/no unknown
- 1995-04-28 FI FI952049A patent/FI952049A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ257470A (en) | 1997-08-22 |
| IL107323A (en) | 2000-06-01 |
| MX9306814A (es) | 1994-07-29 |
| PL178094B1 (pl) | 2000-02-29 |
| RU2126000C1 (ru) | 1999-02-10 |
| SK54795A3 (en) | 1995-12-06 |
| FI952049A0 (fi) | 1995-04-28 |
| BR9307347A (pt) | 1999-05-25 |
| HUT72072A (en) | 1996-03-28 |
| KR950704301A (ko) | 1995-11-17 |
| CA2148003A1 (en) | 1994-05-11 |
| NO951640D0 (no) | 1995-04-28 |
| JPH08502750A (ja) | 1996-03-26 |
| AU687018B2 (en) | 1998-02-19 |
| HU9501237D0 (en) | 1995-06-28 |
| NO951640L (no) | 1995-06-30 |
| AU5409794A (en) | 1994-05-24 |
| CZ109795A3 (en) | 1995-12-13 |
| PL308671A1 (en) | 1995-08-21 |
| EP0666853A1 (en) | 1995-08-16 |
| WO1994010163A1 (en) | 1994-05-11 |
| RU95110762A (ru) | 1997-01-10 |
| ZA938089B (en) | 1994-06-07 |
| CN1092773A (zh) | 1994-09-28 |
| IL107323A0 (en) | 1994-01-25 |
| EG20543A (en) | 1999-07-31 |
| CN1064357C (zh) | 2001-04-11 |
| FI952049A (fi) | 1995-04-28 |
| CZ282581B6 (cs) | 1997-08-13 |
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