FI952049A - Antimikrobiset 5-hydratsino-kinolonijohdannaiset - Google Patents

Antimikrobiset 5-hydratsino-kinolonijohdannaiset Download PDF

Info

Publication number
FI952049A
FI952049A FI952049A FI952049A FI952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A
Authority
FI
Finland
Prior art keywords
hydrazino
antimicrobial
quinolone derivatives
quinolone
derivatives
Prior art date
Application number
FI952049A
Other languages
English (en)
Swedish (sv)
Other versions
FI952049A0 (fi
Inventor
Jr Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI952049A0 publication Critical patent/FI952049A0/fi
Publication of FI952049A publication Critical patent/FI952049A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI952049A 1992-10-30 1995-04-28 Antimikrobiset 5-hydratsino-kinolonijohdannaiset FI952049A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30
PCT/US1993/010091 WO1994010163A1 (en) 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives

Publications (2)

Publication Number Publication Date
FI952049A0 FI952049A0 (fi) 1995-04-28
FI952049A true FI952049A (fi) 1995-04-28

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952049A FI952049A (fi) 1992-10-30 1995-04-28 Antimikrobiset 5-hydratsino-kinolonijohdannaiset

Country Status (21)

Country Link
EP (1) EP0666853A1 (fi)
JP (1) JPH08502750A (fi)
KR (1) KR950704301A (fi)
CN (1) CN1064357C (fi)
AU (1) AU687018B2 (fi)
BR (1) BR9307347A (fi)
CA (1) CA2148003A1 (fi)
CZ (1) CZ282581B6 (fi)
EG (1) EG20543A (fi)
FI (1) FI952049A (fi)
HU (1) HUT72072A (fi)
IL (1) IL107323A (fi)
MX (1) MX9306814A (fi)
NO (1) NO951640L (fi)
NZ (1) NZ257470A (fi)
PL (1) PL178094B1 (fi)
RU (1) RU2126000C1 (fi)
SG (1) SG59979A1 (fi)
SK (1) SK54795A3 (fi)
WO (1) WO1994010163A1 (fi)
ZA (1) ZA938089B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
KR100242355B1 (ko) * 1994-08-02 2000-03-02 데이비드 엠 모이어 항미생물 화합물의 제조 방법
KR100239200B1 (ko) * 1994-08-02 2000-03-02 데이비드 엠 모이어 퀴놀로닐 락탐 항생제의 제조 방법 및 신규 중간체 화합물
IL124944A (en) * 1996-02-09 2003-06-24 Toyama Chemical Co Ltd Quinolonecarboxylic acid derivatives or their salts and pharmaceutical compositions containing them
KR101488403B1 (ko) * 2005-05-18 2015-02-04 엠펙스 파마슈티컬즈, 인코포레이티드 에어로졸화된 플루오로퀴놀론 및 이의 용도
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CA2528849C (en) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (ru) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Производные хинолина в качестве антибактериальных агентов
CN101020647B (zh) * 2007-02-14 2011-03-30 杭州师范学院 一种β-环丙胺基丙烯酸(酯)的合成方法
EP2150544B1 (en) * 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
ES2582662T3 (es) * 2007-10-05 2016-09-14 Senhwa Biosciences, Inc. Análogos de quinolona y procedimientos relacionados con los mismos
AU2009254738B2 (en) * 2008-06-03 2014-05-08 Idorsia Pharmaceuticals Ltd [4-(1-amino-ethyl) -cyclohexyl] -methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl] -methyl-amine derivatives as antibacterials
HUE038428T2 (hu) 2008-10-07 2018-10-29 Horizon Orphan Llc Aeroszol fluorokinolon készítmények javított farmakokinetika érdekében
WO2010042549A1 (en) 2008-10-07 2010-04-15 Mpex Pharmaceuticals, Inc. Inhalation of levofloxacin for reducing lung inflammation
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
PT2473170T (pt) 2009-09-04 2019-08-23 Horizon Orphan Llc Utilização de levofloxacina em aerossol para tratamento de fibrose cística

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
PL166381B1 (pl) * 1989-08-16 1995-05-31 Pfizer Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
EP0525057B1 (en) * 1990-04-18 2000-06-14 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolonyl lactams
DE69131428T2 (de) * 1990-11-30 2000-01-05 Warner-Lambert Co., Ann Arbor Individuelle stereoisomere von 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolone und naphthyridone als antibakterielle wirkstoffe

Also Published As

Publication number Publication date
NZ257470A (en) 1997-08-22
IL107323A (en) 2000-06-01
MX9306814A (es) 1994-07-29
PL178094B1 (pl) 2000-02-29
RU2126000C1 (ru) 1999-02-10
SK54795A3 (en) 1995-12-06
FI952049A0 (fi) 1995-04-28
BR9307347A (pt) 1999-05-25
HUT72072A (en) 1996-03-28
KR950704301A (ko) 1995-11-17
CA2148003A1 (en) 1994-05-11
NO951640D0 (no) 1995-04-28
JPH08502750A (ja) 1996-03-26
AU687018B2 (en) 1998-02-19
HU9501237D0 (en) 1995-06-28
SG59979A1 (en) 1999-02-22
NO951640L (no) 1995-06-30
AU5409794A (en) 1994-05-24
CZ109795A3 (en) 1995-12-13
PL308671A1 (en) 1995-08-21
EP0666853A1 (en) 1995-08-16
WO1994010163A1 (en) 1994-05-11
RU95110762A (ru) 1997-01-10
ZA938089B (en) 1994-06-07
CN1092773A (zh) 1994-09-28
IL107323A0 (en) 1994-01-25
EG20543A (en) 1999-07-31
CN1064357C (zh) 2001-04-11
CZ282581B6 (cs) 1997-08-13

Similar Documents

Publication Publication Date Title
ATA75293A (de) Indolderivate
DE69208877D1 (de) Chinuclidinderivate
NO922182L (no) Krystallinske oksatiolan-derivater
DE59309028D1 (de) Viruswirksame desinfektionsmittel
DE59300018D1 (de) Fungizide Azolylmethyl-fluorcycloproplylderivate.
NO924000D0 (no) Antimikrobielle kinolontiourea-forbindelser
NO920103L (no) Antibakterielle midler
DE69330497D1 (de) Chinazolin-derivate
FI925763A (fi) Fungicida 2-imidazolin-5-on- och 2-imidazolin-5-tionderivat
KR950700911A (ko) 살균약제로서의 치환된 3-피롤리디닐티오-카르바페넴(Substituted 3-Pyrrolidinylthio-Carbapenems as Antimicrobial Agents)
DE59308714D1 (de) Cyclobutan-benzol-derivate
NO305294B1 (no) R°rhenger
FI952049A (fi) Antimikrobiset 5-hydratsino-kinolonijohdannaiset
ATE172738T1 (de) Substituierte 6-aza-androstenone
FI952804A0 (fi) Substituoidut bentsatsepinonit
NO952288D0 (no) Benzazepinon-derivater
FI925469A (fi) Tiazolylsubstituerade kinolylymetoxifenylaettiksyraderivat
DE69313890D1 (de) 5-Aminoflavon-Derivate
MX9206710A (es) Derivados de piridinol
DE59309389D1 (de) Substituierte Thiophencarbonsäureamide
DE69211197D1 (de) 1-Hydroxyvitamin D-Derivate
NO930739D0 (no) Substituerte fenylkinazolinderivater
KR930702353A (ko) 2- 카르바페넴 유도체
NO932638D0 (no) 21-klor-pregnanderivat
DE59310082D1 (de) Substituierte 2-arylpyrrole