FI952049A - Antimikrobiella 5-hydrazino-kinolonderivat - Google Patents

Antimikrobiella 5-hydrazino-kinolonderivat Download PDF

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Publication number
FI952049A
FI952049A FI952049A FI952049A FI952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A FI 952049 A FI952049 A FI 952049A
Authority
FI
Finland
Prior art keywords
hydrazino
antimicrobial
quinolone derivatives
quinolone
derivatives
Prior art date
Application number
FI952049A
Other languages
English (en)
Finnish (fi)
Other versions
FI952049A0 (sv
Inventor
Jr Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI952049A publication Critical patent/FI952049A/sv
Publication of FI952049A0 publication Critical patent/FI952049A0/sv

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI952049A 1992-10-30 1995-04-28 Antimikrobiella 5-hydrazino-kinolonderivat FI952049A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30
PCT/US1993/010091 WO1994010163A1 (en) 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives

Publications (2)

Publication Number Publication Date
FI952049A true FI952049A (sv) 1995-04-28
FI952049A0 FI952049A0 (sv) 1995-04-28

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952049A FI952049A0 (sv) 1992-10-30 1995-04-28 Antimikrobiella 5-hydrazino-kinolonderivat

Country Status (21)

Country Link
EP (1) EP0666853A1 (sv)
JP (1) JPH08502750A (sv)
KR (1) KR950704301A (sv)
CN (1) CN1064357C (sv)
AU (1) AU687018B2 (sv)
BR (1) BR9307347A (sv)
CA (1) CA2148003A1 (sv)
CZ (1) CZ282581B6 (sv)
EG (1) EG20543A (sv)
FI (1) FI952049A0 (sv)
HU (1) HUT72072A (sv)
IL (1) IL107323A (sv)
MX (1) MX9306814A (sv)
NO (1) NO951640L (sv)
NZ (1) NZ257470A (sv)
PL (1) PL178094B1 (sv)
RU (1) RU2126000C1 (sv)
SG (1) SG59979A1 (sv)
SK (1) SK54795A3 (sv)
WO (1) WO1994010163A1 (sv)
ZA (1) ZA938089B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
WO1996004247A1 (en) * 1994-08-02 1996-02-15 The Procter & Gamble Company Process for making antimicrobial compounds
JPH10503521A (ja) * 1994-08-02 1998-03-31 ザ、プロクター、エンド、ギャンブル、カンパニー キノロニルラクタム抗微生物剤の製造方法及び新規中間化合物
WO1997029102A1 (fr) * 1996-02-09 1997-08-14 Toyama Chemical Co., Ltd. Derives de l'acide quinolonecarboxylique et leurs sels
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
AU2006247053B2 (en) * 2005-05-18 2013-05-23 Horizon Therapeutics U.S. Holding Llc Aerosolized fluoroquinolones and uses thereof
CA2528849C (en) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (ru) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Производные хинолина в качестве антибактериальных агентов
CN101020647B (zh) * 2007-02-14 2011-03-30 杭州师范学院 一种β-环丙胺基丙烯酸(酯)的合成方法
EP2150544B1 (en) * 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
EP2214491B1 (en) * 2007-10-05 2016-07-13 Senhwa Biosciences, Inc. Quinolone analogs and methods related thereto
EP2297107B1 (en) * 2008-06-03 2013-11-13 Actelion Pharmaceuticals Ltd. [4-(1-amino-ethyl) -cyclohexyl]-methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl]-methyl-amine derivatives as antibacterials
DK2346509T3 (da) 2008-10-07 2020-08-03 Horizon Orphan Llc Inhalation af levofloxacin til at reducere lungeinflammation
BRPI0920026B1 (pt) 2008-10-07 2023-11-07 Horizon Orphan Llc Composição farmacêutica e respectivos usos
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
IN2012DN02477A (sv) 2009-09-04 2015-08-21 Mpex Pharmaceuticals Inc

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
WO1991002526A1 (en) * 1989-08-16 1991-03-07 Pfizer Inc. Azabicyclo quinolone carboxylic acids
EP0525057B1 (en) * 1990-04-18 2000-06-14 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolonyl lactams
ES2137942T3 (es) * 1990-11-30 2000-01-01 Warner Lambert Co Estereoisomeros individuales de 7-(3-(aminoalquil)-1-pirrolidinil)-quinolonas y de naftiridonas utilizados como agentes antibacterianos.

Also Published As

Publication number Publication date
CZ109795A3 (en) 1995-12-13
IL107323A (en) 2000-06-01
RU2126000C1 (ru) 1999-02-10
CZ282581B6 (cs) 1997-08-13
BR9307347A (pt) 1999-05-25
ZA938089B (en) 1994-06-07
SG59979A1 (en) 1999-02-22
KR950704301A (ko) 1995-11-17
SK54795A3 (en) 1995-12-06
PL178094B1 (pl) 2000-02-29
JPH08502750A (ja) 1996-03-26
CN1064357C (zh) 2001-04-11
FI952049A0 (sv) 1995-04-28
RU95110762A (ru) 1997-01-10
CN1092773A (zh) 1994-09-28
IL107323A0 (en) 1994-01-25
EP0666853A1 (en) 1995-08-16
HU9501237D0 (en) 1995-06-28
WO1994010163A1 (en) 1994-05-11
MX9306814A (es) 1994-07-29
NO951640D0 (no) 1995-04-28
EG20543A (en) 1999-07-31
HUT72072A (en) 1996-03-28
AU5409794A (en) 1994-05-24
AU687018B2 (en) 1998-02-19
NZ257470A (en) 1997-08-22
CA2148003A1 (en) 1994-05-11
NO951640L (no) 1995-06-30
PL308671A1 (en) 1995-08-21

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