NO924000L - Antimikrobielle kinolontiourea-forbindelser - Google Patents
Antimikrobielle kinolontiourea-forbindelserInfo
- Publication number
- NO924000L NO924000L NO92924000A NO924000A NO924000L NO 924000 L NO924000 L NO 924000L NO 92924000 A NO92924000 A NO 92924000A NO 924000 A NO924000 A NO 924000A NO 924000 L NO924000 L NO 924000L
- Authority
- NO
- Norway
- Prior art keywords
- kinolontiourea
- antimicrobial
- compounds
- kinolontiourea compounds
- antimicrobial kinolontiourea
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/513,368 US5328908A (en) | 1988-10-24 | 1990-04-20 | Antimicrobial quinolone thioureas |
PCT/US1991/002203 WO1991016310A1 (en) | 1990-04-20 | 1991-04-01 | Antimicrobial quinolone thioureas |
Publications (4)
Publication Number | Publication Date |
---|---|
NO924000D0 NO924000D0 (no) | 1992-10-15 |
NO924000L true NO924000L (no) | 1992-12-16 |
NO179448B NO179448B (no) | 1996-07-01 |
NO179448C NO179448C (no) | 1996-10-09 |
Family
ID=24042972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO924000A NO179448C (no) | 1990-04-20 | 1992-10-15 | Analogifremgangsmåte for fremstilling av terapeutisk aktive forbindelser |
Country Status (18)
Country | Link |
---|---|
US (2) | US5328908A (no) |
EP (1) | EP0593457A1 (no) |
JP (1) | JP3046068B2 (no) |
KR (1) | KR100256457B1 (no) |
AU (1) | AU659996B2 (no) |
CA (1) | CA2077435A1 (no) |
EG (1) | EG19861A (no) |
FI (1) | FI102897B1 (no) |
IE (1) | IE911324A1 (no) |
IL (1) | IL97737A (no) |
MY (1) | MY111870A (no) |
NO (1) | NO179448C (no) |
NZ (1) | NZ237887A (no) |
PH (1) | PH30053A (no) |
PT (1) | PT97416B (no) |
SG (1) | SG68555A1 (no) |
WO (1) | WO1991016310A1 (no) |
ZA (1) | ZA912494B (no) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
ATE193890T1 (de) * | 1990-04-18 | 2000-06-15 | Procter & Gamble Pharma | Antimikrobielle chinolonyl-lactame |
FR2675144B1 (fr) * | 1991-04-10 | 1995-06-16 | Bouchara Sa | Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant. |
FR2692577B1 (fr) * | 1992-05-26 | 1996-02-02 | Bouchara Sa | Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant. |
AU4272793A (en) * | 1993-04-24 | 1994-11-21 | Korea Research Institute Of Chemical Technology | Novel quinolone carboxylic acid derivatives and process for preparing the same |
TW252107B (no) * | 1993-08-27 | 1995-07-21 | Hokuriku Pharmacetical Co Ltd | |
KR950018003A (ko) * | 1993-12-09 | 1995-07-22 | 스미스클라인 비참 피엘씨 | 신규한 퀴놀론 유도체 및 그의 제조 방법 |
KR100239200B1 (ko) * | 1994-08-02 | 2000-03-02 | 데이비드 엠 모이어 | 퀴놀로닐 락탐 항생제의 제조 방법 및 신규 중간체 화합물 |
DE4427530A1 (de) * | 1994-08-04 | 1996-02-08 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäure-Derivate |
DE69617750T2 (de) * | 1995-09-22 | 2002-08-08 | Wakunaga Pharma Co Ltd | Neue pyridoncarbonsäure-derivate oder ihre salze und antibakterielle mittel, die diese als aktiven wirkstoff enthalten |
KR20000068711A (ko) | 1997-08-06 | 2000-11-25 | 도리이 신이치로 | Ⅳ형 포스포디에스테라제 억제제로서의 1-아릴-1,8-나프틸리딘-4-온 유도체 |
SK286420B6 (sk) * | 1997-09-15 | 2008-09-05 | The Procter & Gamble Company | Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie |
CA2429951A1 (en) | 2000-12-14 | 2002-06-20 | The Procter & Gamble Company | Antimicrobial quinolones |
AU3089302A (en) | 2000-12-14 | 2002-06-24 | Procter & Gamble | Antimicrobial 2-pyridones, their compositions and uses |
IS7839A (is) * | 2002-11-22 | 2004-05-23 | Merck Frosst Canada Ltd. | 4-oxó-1-(3-setið fenýl-1,4-díhýdró-1,8-naftýridín-3-karboxamíð fosfódíesterasa-4 hindrar |
KR20060069836A (ko) * | 2003-08-12 | 2006-06-22 | 아칠리온 파르마세우티칼스 인코포레이티드 | 항-감염제로서의 이소티아졸로퀴놀론 및 관련 화합물 |
DE10351448A1 (de) * | 2003-11-04 | 2005-06-09 | Bayer Healthcare Ag | Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften |
JP2008509909A (ja) * | 2004-08-11 | 2008-04-03 | ウィリアムスバーグ・ホールディングス・エルエルシー | 心毒性のない医薬化合物 |
CN101120004A (zh) * | 2004-11-11 | 2008-02-06 | 艾其林医药公司 | 用作抗感染剂的8a,9-二氢-4a-h-异噻唑[5,4-b]喹啉-3,4-二酮及相关化合物 |
US7659399B2 (en) * | 2005-01-05 | 2010-02-09 | Achillion Pharmaceuticals, Inc. | 1-thia-2,4a-diaza-cyclopenta[b]napththalene-3,4-diones and related compounds as anti-infective agents |
US7199128B2 (en) | 2005-02-02 | 2007-04-03 | Achillion Pharmaceuticals, Inc. | 8-N-substituted-2H-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents |
NZ561005A (en) * | 2005-02-16 | 2011-04-29 | Achillion Pharmaceuticals Inc | New isothiazoloquinolones and related compounds as anti-infective agents |
DK1913004T3 (da) | 2005-07-27 | 2011-01-10 | Achillion Pharmaceuticals Inc | 8-methoxy-9h-isothiazolo[5,4-b]quinolin-3,4-dioner og beslægtede forbindelser som antiinfektive midler |
US7456279B2 (en) * | 2006-03-28 | 2008-11-25 | The Procter & Gamble Company | Coupling process for preparing quinolone intermediates |
WO2007110834A2 (en) * | 2006-03-28 | 2007-10-04 | The Procter & Gamble Company | Malate salts, and polymorphs of (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid |
CA2756701A1 (en) * | 2009-04-03 | 2010-10-07 | Achillion Pharmaceuticals, Inc. | Hydroxythienoquinolones and related compounds as anti-infective agents |
Family Cites Families (46)
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YU33873B (en) * | 1968-08-08 | 1978-06-30 | Pliva Pharm & Chem Works | Process for the preparation of the novel 6-nalidixyl-penicillanic acid |
JPS5219561Y2 (no) * | 1971-03-05 | 1977-05-06 | ||
AR204813A1 (es) * | 1972-05-08 | 1976-03-05 | Yamanouchi Pharma Co Ltd | Proceso para la preparacion de derivados de ampilicina |
FR2191556A5 (en) * | 1972-06-29 | 1974-02-01 | Aries Robert | N-Acylampicillins - with broad-spectrum antibacterial activity prepd. by acylation with naphthyridine carboxylic acids |
JPS4935392A (no) * | 1972-08-02 | 1974-04-01 | ||
JPS5023037A (no) * | 1973-07-03 | 1975-03-12 | ||
JPS5023036A (no) * | 1973-07-06 | 1975-03-12 | ||
FR2243940A1 (en) * | 1973-09-17 | 1975-04-11 | Aries Robert | Antibacterial nalidixamido cephems - prepd from 7-amino cephem (salt) and nalidixic acid deriv |
US3939150A (en) * | 1973-10-19 | 1976-02-17 | Yamanouchi Pharmaceutical Co., Ltd. | Penicillin derivatives |
GB1509074A (en) * | 1974-04-05 | 1978-04-26 | Yamanouchi Pharma Co Ltd | Cephalosporin derivatives |
JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
JPS5573686A (en) * | 1978-11-28 | 1980-06-03 | Mitsui Toatsu Chem Inc | Novel penicillin |
JPS5732290A (en) * | 1980-08-06 | 1982-02-20 | Fujimoto Seiyaku Kk | Novel penicillin derivative and its preparation |
JPS5746988A (en) * | 1980-09-03 | 1982-03-17 | Fujimoto Seiyaku Kk | Novel penicillin derivative and its preparation |
JPS5746990A (en) * | 1980-09-03 | 1982-03-17 | Fujimoto Seiyaku Kk | Novel cephalexin derivative and its preparation |
US4620007A (en) * | 1980-09-03 | 1986-10-28 | Bayer Aktiengesellschaft | 6-fluoro-7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid |
US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
WO1982001873A1 (en) * | 1980-12-05 | 1982-06-10 | Takeda Chemical Industries Ltd | 1-sulfo-2-oxoazetidine derivatives and process for their preparation |
US4468394A (en) * | 1981-04-02 | 1984-08-28 | Eisai Co., Ltd. | Cephalosporin compounds |
US4546176A (en) * | 1982-12-14 | 1985-10-08 | Eisai Co., Ltd. | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same |
DE3308909A1 (de) * | 1983-03-12 | 1984-09-13 | Bayer Ag, 5090 Leverkusen | Bakterizide mittel auf chinoloncarbonsaeure-basis |
JPS606617A (ja) * | 1983-05-09 | 1985-01-14 | Kyorin Pharmaceut Co Ltd | 抗菌性組成物 |
GB8321677D0 (en) * | 1983-08-11 | 1983-09-14 | Erba Farmitalia | Preparation of penems |
EP0182210B1 (en) * | 1984-11-12 | 1991-02-27 | Banyu Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
IT1215277B (it) * | 1985-05-27 | 1990-01-31 | Pomezia Roma A | Derivato chinolin-lattaminico ad attivita' antibatterica ed inibitrice delle b-lattamasi. |
GB8626245D0 (en) * | 1985-11-27 | 1986-12-03 | Ici Pharma | Cephalosporin compounds |
US4783443A (en) * | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
ZA874696B (en) * | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
US4954507A (en) * | 1986-10-08 | 1990-09-04 | Bristol-Myers Company | 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents |
HU200917B (en) * | 1987-07-20 | 1990-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical compositions comprising quinoline or naphthyridinecarboxylic acid and tetracycline derivatives as active ingredient |
EP0304155B1 (en) * | 1987-07-23 | 1995-11-15 | ZENECA Pharma S.A. | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions |
GB8816519D0 (en) * | 1987-07-23 | 1988-08-17 | Ici Plc | Antibiotic compounds |
NZ227470A (en) * | 1987-12-28 | 1991-06-25 | Hoffmann La Roche | Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment |
HUT49889A (en) * | 1988-03-31 | 1989-11-28 | Hoffmann La Roche | Process for producing acyl derivatives |
JPH01258684A (ja) * | 1988-04-07 | 1989-10-16 | Banyu Pharmaceut Co Ltd | 3‐置換キノリニウムチオメチルセファロスポリン誘導体 |
ATE113953T1 (de) * | 1988-05-10 | 1994-11-15 | Ici Plc | Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. |
EP0366193A3 (en) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial quinolonyl lactams |
ATE194353T1 (de) * | 1988-10-24 | 2000-07-15 | Norwich Eaton Pharma | Antimikrobielle quinolonyllactamester |
US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
SG54293A1 (en) * | 1988-10-24 | 1998-11-16 | Procter & Gamble Pharma | Novel antimicrobial fluoroquinolonyl cephems |
CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
ZA912279B (en) * | 1990-04-09 | 1992-02-26 | Hoffmann La Roche | Carbapenem compounds |
ATE193890T1 (de) * | 1990-04-18 | 2000-06-15 | Procter & Gamble Pharma | Antimikrobielle chinolonyl-lactame |
US5066800A (en) * | 1990-04-27 | 1991-11-19 | Hoffmann-La Roche Inc. | Qunoline intermediates useful therein for synthesizing antibacterial compounds |
US5112967A (en) * | 1990-04-27 | 1992-05-12 | Hoffmann-La Roches Inc. | Process for synthesizing antibacterial cephalosporin compounds |
-
1990
- 1990-04-20 US US07/513,368 patent/US5328908A/en not_active Expired - Fee Related
-
1991
- 1991-03-31 IL IL9773791A patent/IL97737A/en not_active IP Right Cessation
- 1991-04-01 AU AU77415/91A patent/AU659996B2/en not_active Ceased
- 1991-04-01 PH PH42230A patent/PH30053A/en unknown
- 1991-04-01 EP EP91908276A patent/EP0593457A1/en not_active Ceased
- 1991-04-01 WO PCT/US1991/002203 patent/WO1991016310A1/en not_active Application Discontinuation
- 1991-04-01 CA CA002077435A patent/CA2077435A1/en not_active Abandoned
- 1991-04-01 KR KR1019920702587A patent/KR100256457B1/ko not_active IP Right Cessation
- 1991-04-01 JP JP3507992A patent/JP3046068B2/ja not_active Expired - Lifetime
- 1991-04-01 SG SG1996003367A patent/SG68555A1/en unknown
- 1991-04-02 MY MYPI91000547A patent/MY111870A/en unknown
- 1991-04-04 ZA ZA912494A patent/ZA912494B/xx unknown
- 1991-04-14 EG EG22191A patent/EG19861A/xx active
- 1991-04-19 IE IE132491A patent/IE911324A1/en unknown
- 1991-04-19 NZ NZ237887A patent/NZ237887A/en unknown
- 1991-04-19 PT PT97416A patent/PT97416B/pt not_active IP Right Cessation
-
1992
- 1992-10-15 FI FI924672A patent/FI102897B1/fi active
- 1992-10-15 NO NO924000A patent/NO179448C/no not_active IP Right Cessation
-
1994
- 1994-04-08 US US08/225,123 patent/US5631256A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR930700450A (ko) | 1993-03-15 |
ZA912494B (en) | 1992-01-29 |
KR100256457B1 (ko) | 2001-04-02 |
PT97416A (pt) | 1992-01-31 |
US5631256A (en) | 1997-05-20 |
NO179448B (no) | 1996-07-01 |
EP0593457A1 (en) | 1994-04-27 |
AU7741591A (en) | 1991-11-11 |
FI102897B (fi) | 1999-03-15 |
CA2077435A1 (en) | 1991-10-21 |
MY111870A (en) | 2001-02-28 |
IL97737A0 (en) | 1992-06-21 |
WO1991016310A1 (en) | 1991-10-31 |
FI102897B1 (fi) | 1999-03-15 |
NZ237887A (en) | 1996-10-28 |
FI924672A (fi) | 1992-10-15 |
AU659996B2 (en) | 1995-06-08 |
PH30053A (en) | 1996-11-08 |
US5328908A (en) | 1994-07-12 |
IE911324A1 (en) | 1991-10-23 |
EG19861A (en) | 1996-03-31 |
JP3046068B2 (ja) | 2000-05-29 |
NO179448C (no) | 1996-10-09 |
IL97737A (en) | 1995-12-08 |
EP0593457A4 (en) | 1993-01-15 |
NO924000D0 (no) | 1992-10-15 |
SG68555A1 (en) | 1999-11-16 |
FI924672A0 (fi) | 1992-10-15 |
PT97416B (pt) | 1998-08-31 |
JPH05506032A (ja) | 1993-09-02 |
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