IL107323A - Pharmaceutical compositions containing 5-(N-heterosubstituted amino) quinolones and several such new compounds - Google Patents
Pharmaceutical compositions containing 5-(N-heterosubstituted amino) quinolones and several such new compoundsInfo
- Publication number
- IL107323A IL107323A IL10732393A IL10732393A IL107323A IL 107323 A IL107323 A IL 107323A IL 10732393 A IL10732393 A IL 10732393A IL 10732393 A IL10732393 A IL 10732393A IL 107323 A IL107323 A IL 107323A
- Authority
- IL
- Israel
- Prior art keywords
- quinolones
- several
- pharmaceutical compositions
- compositions containing
- new compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96896092A | 1992-10-30 | 1992-10-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL107323A0 IL107323A0 (en) | 1994-01-25 |
| IL107323A true IL107323A (en) | 2000-06-01 |
Family
ID=25514997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10732393A IL107323A (en) | 1992-10-30 | 1993-10-19 | Pharmaceutical compositions containing 5-(N-heterosubstituted amino) quinolones and several such new compounds |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0666853A1 (en) |
| JP (1) | JPH08502750A (en) |
| KR (1) | KR950704301A (en) |
| CN (1) | CN1064357C (en) |
| AU (1) | AU687018B2 (en) |
| BR (1) | BR9307347A (en) |
| CA (1) | CA2148003A1 (en) |
| CZ (1) | CZ282581B6 (en) |
| EG (1) | EG20543A (en) |
| FI (1) | FI952049A (en) |
| HU (1) | HUT72072A (en) |
| IL (1) | IL107323A (en) |
| MX (1) | MX9306814A (en) |
| NO (1) | NO951640L (en) |
| NZ (1) | NZ257470A (en) |
| PL (1) | PL178094B1 (en) |
| RU (1) | RU2126000C1 (en) |
| SG (1) | SG59979A1 (en) |
| SK (1) | SK54795A3 (en) |
| WO (1) | WO1994010163A1 (en) |
| ZA (1) | ZA938089B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| ATE190972T1 (en) * | 1994-08-02 | 2000-04-15 | Procter & Gamble | METHOD FOR PRODUCING ANTIMICROBIAL COMPOUNDS |
| EP0775145A1 (en) * | 1994-08-02 | 1997-05-28 | The Procter & Gamble Company | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds |
| CA2242242C (en) * | 1996-02-09 | 2001-08-07 | Toyama Chemical Co., Ltd. | Quinolonecarboxylic acid derivatives or salts thereof |
| US8524734B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| PT1901749T (en) * | 2005-05-18 | 2016-11-04 | Raptor Pharmaceuticals Inc | Aerosolized fluoroquinolones and uses thereof |
| EE05697B1 (en) | 2005-06-08 | 2014-02-17 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
| EA010601B1 (en) * | 2005-06-09 | 2008-10-30 | Янссен Фармацевтика Н.В. | Quinoline derivatives as antibacterial agents |
| CN101020647B (en) * | 2007-02-14 | 2011-03-30 | 杭州师范学院 | Synthesis process of beta-cyclopropylamino acrylate |
| US8063066B2 (en) | 2007-03-19 | 2011-11-22 | Takeda Pharmaceutical Company Limited | MAPK/ERK kinase inhibitors |
| DK3092901T3 (en) * | 2007-10-05 | 2020-05-18 | Senhwa Biosciences Inc | QUINOLON ANALOGS AND PROCEDURES RELATED |
| MX2010012855A (en) * | 2008-06-03 | 2010-12-21 | Actelion Pharmaceuticals Ltd | [4-(1-amino-ethyl) -cyclohexyl] -methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl] -methyl-amine derivatives as antibacterials. |
| ES2809177T3 (en) | 2008-10-07 | 2021-03-03 | Horizon Orphan Llc | Inhalation of levofloxacin to reduce lung inflammation |
| JP2012505223A (en) | 2008-10-07 | 2012-03-01 | エムペックス・ファーマシューティカルズ・インコーポレーテッド | Aerosol fluoroquinolone formulation for improved pharmacokinetics |
| AR076222A1 (en) * | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| CA2773033C (en) | 2009-09-04 | 2016-10-11 | Mpex Pharmaceuticals, Inc. | Use of aerosolized levofloxacin for treating cystic fibrosis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668680A (en) * | 1985-12-12 | 1987-05-26 | Warner-Lambert Company | 5-amino-6,8-difluoroquinolones as antibacterial agents |
| JPH0228178A (en) * | 1988-04-23 | 1990-01-30 | Toyama Chem Co Ltd | Novel pyridonecarboxylic acid derivative and salt thereof |
| DE3906365A1 (en) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM |
| IE66202B1 (en) * | 1989-08-16 | 1995-12-13 | Pfizer | Azabicyclo quinolone carboxylic acids |
| JPH05506033A (en) * | 1990-04-18 | 1993-09-02 | ノーウィッチ、イートン、ファーマスーティカルズ、インコーポレーテッド | Antimicrobial quinolonyl lactams |
| WO1992009596A1 (en) * | 1990-11-30 | 1992-06-11 | Warner-Lambert Company | Individual stereoisomers of 7-[3-(1-aminoalkyl)-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents |
-
1993
- 1993-01-30 EG EG68693A patent/EG20543A/en active
- 1993-10-19 IL IL10732393A patent/IL107323A/en not_active IP Right Cessation
- 1993-10-22 BR BR9307347A patent/BR9307347A/en not_active Application Discontinuation
- 1993-10-22 AU AU54097/94A patent/AU687018B2/en not_active Ceased
- 1993-10-22 NZ NZ257470A patent/NZ257470A/en unknown
- 1993-10-22 EP EP93924393A patent/EP0666853A1/en not_active Withdrawn
- 1993-10-22 PL PL93308671A patent/PL178094B1/en unknown
- 1993-10-22 SG SG1996007851A patent/SG59979A1/en unknown
- 1993-10-22 RU RU95110762A patent/RU2126000C1/en active
- 1993-10-22 JP JP6511167A patent/JPH08502750A/en active Pending
- 1993-10-22 CZ CZ951097A patent/CZ282581B6/en not_active IP Right Cessation
- 1993-10-22 HU HU9501237A patent/HUT72072A/en unknown
- 1993-10-22 KR KR1019950701690A patent/KR950704301A/en active IP Right Grant
- 1993-10-22 SK SK547-95A patent/SK54795A3/en unknown
- 1993-10-22 CA CA002148003A patent/CA2148003A1/en not_active Abandoned
- 1993-10-22 WO PCT/US1993/010091 patent/WO1994010163A1/en not_active Application Discontinuation
- 1993-10-29 MX MX9306814A patent/MX9306814A/en not_active IP Right Cessation
- 1993-10-29 ZA ZA938089A patent/ZA938089B/en unknown
- 1993-10-30 CN CN93120224A patent/CN1064357C/en not_active Expired - Fee Related
-
1995
- 1995-04-28 FI FI952049A patent/FI952049A/en unknown
- 1995-04-28 NO NO951640A patent/NO951640L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9306814A (en) | 1994-07-29 |
| CA2148003A1 (en) | 1994-05-11 |
| ZA938089B (en) | 1994-06-07 |
| SK54795A3 (en) | 1995-12-06 |
| BR9307347A (en) | 1999-05-25 |
| HUT72072A (en) | 1996-03-28 |
| PL178094B1 (en) | 2000-02-29 |
| NZ257470A (en) | 1997-08-22 |
| EG20543A (en) | 1999-07-31 |
| KR950704301A (en) | 1995-11-17 |
| NO951640D0 (en) | 1995-04-28 |
| AU687018B2 (en) | 1998-02-19 |
| SG59979A1 (en) | 1999-02-22 |
| FI952049A0 (en) | 1995-04-28 |
| RU95110762A (en) | 1997-01-10 |
| CN1064357C (en) | 2001-04-11 |
| JPH08502750A (en) | 1996-03-26 |
| NO951640L (en) | 1995-06-30 |
| IL107323A0 (en) | 1994-01-25 |
| WO1994010163A1 (en) | 1994-05-11 |
| FI952049A (en) | 1995-04-28 |
| CN1092773A (en) | 1994-09-28 |
| EP0666853A1 (en) | 1995-08-16 |
| HU9501237D0 (en) | 1995-06-28 |
| RU2126000C1 (en) | 1999-02-10 |
| CZ282581B6 (en) | 1997-08-13 |
| CZ109795A3 (en) | 1995-12-13 |
| AU5409794A (en) | 1994-05-24 |
| PL308671A1 (en) | 1995-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |