SG59979A1 - Antimicrobial 5-hydrazino-quinolone derivatives - Google Patents

Antimicrobial 5-hydrazino-quinolone derivatives

Info

Publication number
SG59979A1
SG59979A1 SG1996007851A SG1996007851A SG59979A1 SG 59979 A1 SG59979 A1 SG 59979A1 SG 1996007851 A SG1996007851 A SG 1996007851A SG 1996007851 A SG1996007851 A SG 1996007851A SG 59979 A1 SG59979 A1 SG 59979A1
Authority
SG
Singapore
Prior art keywords
hydrazino
antimicrobial
quinolone derivatives
quinolone
derivatives
Prior art date
Application number
SG1996007851A
Inventor
Thomas Prosser Demuth Jr
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of SG59979A1 publication Critical patent/SG59979A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SG1996007851A 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives SG59979A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30

Publications (1)

Publication Number Publication Date
SG59979A1 true SG59979A1 (en) 1999-02-22

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996007851A SG59979A1 (en) 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives

Country Status (21)

Country Link
EP (1) EP0666853A1 (en)
JP (1) JPH08502750A (en)
KR (1) KR950704301A (en)
CN (1) CN1064357C (en)
AU (1) AU687018B2 (en)
BR (1) BR9307347A (en)
CA (1) CA2148003A1 (en)
CZ (1) CZ282581B6 (en)
EG (1) EG20543A (en)
FI (1) FI952049A0 (en)
HU (1) HUT72072A (en)
IL (1) IL107323A (en)
MX (1) MX9306814A (en)
NO (1) NO951640L (en)
NZ (1) NZ257470A (en)
PL (1) PL178094B1 (en)
RU (1) RU2126000C1 (en)
SG (1) SG59979A1 (en)
SK (1) SK54795A3 (en)
WO (1) WO1994010163A1 (en)
ZA (1) ZA938089B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
NZ290721A (en) * 1994-08-02 1999-03-29 Procter & Gamble Process for making quinolone-containing antimicrobial compounds
CA2196539C (en) * 1994-08-02 2001-05-15 The Procter & Gamble Company Process for making quinolonyl lactam antimicrobials and novel intermediate compounds
PT882725E (en) * 1996-02-09 2003-04-30 Toyama Chemical Co Ltd DERIVATIVES OF QUINOLONACARBOXYLIC ACID OR ITS SALTS
PT2594272T (en) * 2005-05-18 2018-07-31 Horizon Orphan Llc Aerosolized fluoroquinolones and uses thereof
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CA2528849C (en) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (en) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Quinoline derivatives as antibacterial agents
CN101020647B (en) * 2007-02-14 2011-03-30 杭州师范学院 Synthesis process of beta-cyclopropylamino acrylate
WO2008115890A2 (en) * 2007-03-19 2008-09-25 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
RU2549895C2 (en) * 2007-10-05 2015-05-10 Сенхва Байосайенсиз,Инк. Quinolone analogues and related methods
BRPI0913093A2 (en) * 2008-06-03 2018-02-06 Actelion Pharmaceuticals Ltd COMPONENTS DERIVED FROM [4- (1-AMINO-ETHYL) -CYCLOEXYL] - METHYL-AMINE AND [6- (1-AMINO-ETHYL) -TETRAHYDRO-PYRAN-3-IL] - METHYL-AMINE, MEDICINE, PHARMACEUTICAL COMPOSITION THAT CONTAINS THAT COMPOUND AND USE OF THEM
HUE038428T2 (en) 2008-10-07 2018-10-29 Horizon Orphan Llc Aerosol fluoroquinolone formulations for improved pharmacokinetics
SI2346509T1 (en) 2008-10-07 2020-08-31 Horizon Orphan Llc Inhalation of levofloxacin for reducing lung inflammation
AR076222A1 (en) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
BR112012004692B8 (en) 2009-09-04 2021-05-25 Mpex Pharmaceuticals Inc solution comprising levofloxacin for use in a method of treating cystic fibrosis in a human.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (en) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd Novel pyridonecarboxylic acid derivative and salt thereof
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
RU2049777C1 (en) * 1989-08-16 1995-12-10 Пфайзер Инк. Azabicyclo-quinolone caroboxylic acids or their pharmaceutically acceptable acid-additive salts and intermediate products for their synthesis
EP0525057B1 (en) * 1990-04-18 2000-06-14 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolonyl lactams
DE69131428T2 (en) * 1990-11-30 2000-01-05 Warner Lambert Co INDIVIDUAL STEREOISOMERS OF 7- [3- (AMINOALKYL) -1-PYRROLIDINYL] QUINOLONE AND NAPHTHYRIDONE AS AN ANTIBACTERIAL ACTIVE SUBSTANCES

Also Published As

Publication number Publication date
IL107323A0 (en) 1994-01-25
MX9306814A (en) 1994-07-29
PL308671A1 (en) 1995-08-21
JPH08502750A (en) 1996-03-26
CZ109795A3 (en) 1995-12-13
SK54795A3 (en) 1995-12-06
NO951640L (en) 1995-06-30
AU687018B2 (en) 1998-02-19
NO951640D0 (en) 1995-04-28
HU9501237D0 (en) 1995-06-28
HUT72072A (en) 1996-03-28
EG20543A (en) 1999-07-31
BR9307347A (en) 1999-05-25
KR950704301A (en) 1995-11-17
NZ257470A (en) 1997-08-22
IL107323A (en) 2000-06-01
CZ282581B6 (en) 1997-08-13
ZA938089B (en) 1994-06-07
CA2148003A1 (en) 1994-05-11
PL178094B1 (en) 2000-02-29
EP0666853A1 (en) 1995-08-16
CN1064357C (en) 2001-04-11
WO1994010163A1 (en) 1994-05-11
RU2126000C1 (en) 1999-02-10
FI952049A (en) 1995-04-28
FI952049A0 (en) 1995-04-28
AU5409794A (en) 1994-05-24
CN1092773A (en) 1994-09-28
RU95110762A (en) 1997-01-10

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