HU9501237D0 - Antimicrobial 5-hydrazino-quinolone derivatives - Google Patents

Antimicrobial 5-hydrazino-quinolone derivatives

Info

Publication number
HU9501237D0
HU9501237D0 HU9501237A HU9501237A HU9501237D0 HU 9501237 D0 HU9501237 D0 HU 9501237D0 HU 9501237 A HU9501237 A HU 9501237A HU 9501237 A HU9501237 A HU 9501237A HU 9501237 D0 HU9501237 D0 HU 9501237D0
Authority
HU
Hungary
Prior art keywords
hydrazino
antimicrobial
quinolone derivatives
quinolone
derivatives
Prior art date
Application number
HU9501237A
Other languages
Hungarian (hu)
Other versions
HUT72072A (en
Inventor
Thomas Demuth
Ronald White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of HU9501237D0 publication Critical patent/HU9501237D0/en
Publication of HUT72072A publication Critical patent/HUT72072A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HU9501237A 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives and pharmaceutical compositions containing them HUT72072A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30

Publications (2)

Publication Number Publication Date
HU9501237D0 true HU9501237D0 (en) 1995-06-28
HUT72072A HUT72072A (en) 1996-03-28

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9501237A HUT72072A (en) 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives and pharmaceutical compositions containing them

Country Status (21)

Country Link
EP (1) EP0666853A1 (en)
JP (1) JPH08502750A (en)
KR (1) KR950704301A (en)
CN (1) CN1064357C (en)
AU (1) AU687018B2 (en)
BR (1) BR9307347A (en)
CA (1) CA2148003A1 (en)
CZ (1) CZ282581B6 (en)
EG (1) EG20543A (en)
FI (1) FI952049A (en)
HU (1) HUT72072A (en)
IL (1) IL107323A (en)
MX (1) MX9306814A (en)
NO (1) NO951640L (en)
NZ (1) NZ257470A (en)
PL (1) PL178094B1 (en)
RU (1) RU2126000C1 (en)
SG (1) SG59979A1 (en)
SK (1) SK54795A3 (en)
WO (1) WO1994010163A1 (en)
ZA (1) ZA938089B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
CN1159809A (en) * 1994-08-02 1997-09-17 普罗克特和甘保尔公司 Process for making quinolonyl lactam antimicrobials and novel intermediate compounds
JPH10504815A (en) * 1994-08-02 1998-05-12 ザ、プロクター、エンド、ギャンブル、カンパニー Method for producing antimicrobial compound
KR100276477B1 (en) * 1996-02-09 2000-12-15 나카노 가쓰히코 Quinolonecarboxylic acid derivatives or salts thereof
HUE030419T2 (en) * 2005-05-18 2017-05-29 Horizon Orphan Llc Aerosolized fluoroquinolones and uses thereof
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
EE05697B1 (en) 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (en) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Quinoline derivatives as antibacterial agents
CN101020647B (en) * 2007-02-14 2011-03-30 杭州师范学院 Synthesis process of beta-cyclopropylamino acrylate
EP2150544B1 (en) 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
PT2214491T (en) * 2007-10-05 2016-10-25 Senhwa Biosciences Inc Quinolone analogs and methods related thereto
JP5639581B2 (en) * 2008-06-03 2014-12-10 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd [4- (1-Amino-ethyl) -cyclohexyl] -methyl-amine and [6- (1-amino-ethyl) -tetrahydro-pyran-3-yl] -methyl-amine derivatives as antibacterial agents
PL2346509T3 (en) 2008-10-07 2021-03-08 Horizon Orphan Llc Inhalation of levofloxacin for reducing lung inflammation
KR20110091510A (en) 2008-10-07 2011-08-11 엠펙스 파마슈티컬즈, 인코포레이티드 Aerosol fluoroquinolone formulations for improved pharmacokinetics
AR076222A1 (en) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SI2473170T1 (en) 2009-09-04 2019-10-30 Horizon Orphan Llc Use of aerosolized levofloxacin for treating cystic fibrosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (en) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd Novel pyridonecarboxylic acid derivative and salt thereof
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
HU219403B (en) * 1989-08-16 2001-04-28 Pfizer Inc. Azabicyclo-substituted quinolone and naphthyridone carboxylic acids and process for producing them
ATE193890T1 (en) * 1990-04-18 2000-06-15 Procter & Gamble Pharma ANTIMICROBIAL QUINOLONYL LACTAMES
DE69131428T2 (en) * 1990-11-30 2000-01-05 Warner Lambert Co INDIVIDUAL STEREOISOMERS OF 7- [3- (AMINOALKYL) -1-PYRROLIDINYL] QUINOLONE AND NAPHTHYRIDONE AS AN ANTIBACTERIAL ACTIVE SUBSTANCES

Also Published As

Publication number Publication date
PL178094B1 (en) 2000-02-29
EP0666853A1 (en) 1995-08-16
PL308671A1 (en) 1995-08-21
CZ282581B6 (en) 1997-08-13
RU2126000C1 (en) 1999-02-10
CA2148003A1 (en) 1994-05-11
WO1994010163A1 (en) 1994-05-11
SG59979A1 (en) 1999-02-22
MX9306814A (en) 1994-07-29
EG20543A (en) 1999-07-31
NO951640L (en) 1995-06-30
NO951640D0 (en) 1995-04-28
RU95110762A (en) 1997-01-10
NZ257470A (en) 1997-08-22
CN1064357C (en) 2001-04-11
AU687018B2 (en) 1998-02-19
IL107323A0 (en) 1994-01-25
ZA938089B (en) 1994-06-07
AU5409794A (en) 1994-05-24
JPH08502750A (en) 1996-03-26
FI952049A0 (en) 1995-04-28
SK54795A3 (en) 1995-12-06
CZ109795A3 (en) 1995-12-13
FI952049A (en) 1995-04-28
BR9307347A (en) 1999-05-25
CN1092773A (en) 1994-09-28
KR950704301A (en) 1995-11-17
IL107323A (en) 2000-06-01
HUT72072A (en) 1996-03-28

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Legal Events

Date Code Title Description
DFA9 Temporary protection cancelled due to abandonment