SG55152A1 - Hepatitis b virus surface proteins with reduced host carbohydrate content - Google Patents
Hepatitis b virus surface proteins with reduced host carbohydrate contentInfo
- Publication number
- SG55152A1 SG55152A1 SG1996008131A SG1996008131A SG55152A1 SG 55152 A1 SG55152 A1 SG 55152A1 SG 1996008131 A SG1996008131 A SG 1996008131A SG 1996008131 A SG1996008131 A SG 1996008131A SG 55152 A1 SG55152 A1 SG 55152A1
- Authority
- SG
- Singapore
- Prior art keywords
- hbv
- surface proteins
- hepatitis
- carbohydrate content
- particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69292491A | 1991-04-29 | 1991-04-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG55152A1 true SG55152A1 (en) | 1998-12-21 |
Family
ID=24782605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG1996008131A SG55152A1 (en) | 1991-04-29 | 1992-04-29 | Hepatitis b virus surface proteins with reduced host carbohydrate content |
Country Status (25)
Country | Link |
---|---|
US (1) | US5614384A (pl) |
EP (1) | EP0516286B1 (pl) |
JP (1) | JP2637877B2 (pl) |
KR (1) | KR920019373A (pl) |
CN (1) | CN1067680A (pl) |
AT (1) | ATE215987T1 (pl) |
AU (1) | AU650530B2 (pl) |
BG (1) | BG61700B1 (pl) |
CA (1) | CA2067290A1 (pl) |
CZ (1) | CZ282769B6 (pl) |
DE (1) | DE69232541D1 (pl) |
FI (1) | FI934650A (pl) |
HU (1) | HUT69149A (pl) |
IE (1) | IE921385A1 (pl) |
IL (1) | IL101651A0 (pl) |
LT (1) | LT3367B (pl) |
MX (1) | MX9201970A (pl) |
NO (1) | NO933897L (pl) |
NZ (1) | NZ242487A (pl) |
PL (1) | PL171485B1 (pl) |
SG (1) | SG55152A1 (pl) |
SK (1) | SK118193A3 (pl) |
WO (1) | WO1992019741A1 (pl) |
YU (1) | YU45492A (pl) |
ZA (1) | ZA923069B (pl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0533263A3 (en) * | 1991-09-20 | 1994-06-08 | Merck & Co Inc | A multivalent hepatitis b virus vaccine |
WO1995031558A1 (en) * | 1994-05-16 | 1995-11-23 | Merck & Co., Inc. | Process for producing hbv surface proteins |
US6300065B1 (en) * | 1996-05-31 | 2001-10-09 | Board Of Trustees Of The University Of Illinois | Yeast cell surface display of proteins and uses thereof |
US6696251B1 (en) * | 1996-05-31 | 2004-02-24 | Board Of Trustees Of The University Of Illinois | Yeast cell surface display of proteins and uses thereof |
JP2002532116A (ja) * | 1998-12-23 | 2002-10-02 | メルク エンド カムパニー インコーポレーテッド | 改良された組換えb型肝炎表面抗原 |
KR100604994B1 (ko) | 2004-01-30 | 2006-07-26 | 한국생명공학연구원 | 알파1,6-만노실트랜스퍼라제를 코딩하는 한세눌라폴리모르파 기원의 신규 유전자 및 상기 유전자가 결손된한세눌라 폴리모르파 변이주를 이용한 재조합 당단백질생산 방법 |
CN111187720A (zh) * | 2019-12-27 | 2020-05-22 | 深圳康泰生物制品股份有限公司 | 表达肠道病毒71型抗原的重组汉逊酵母的细胞破碎方法及其在制备手足口病疫苗中的应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4803164A (en) * | 1981-08-31 | 1989-02-07 | Genentech, Inc. | Preparation of hepatitis b surface antigen in yeast |
US4707542A (en) * | 1983-08-22 | 1987-11-17 | Merck & Co., Inc. | Immunogenic HbsAg derived from transformed yeast |
US4816564A (en) * | 1986-01-31 | 1989-03-28 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
GB8613388D0 (en) * | 1986-06-03 | 1986-07-09 | Delta Biotechnology Ltd | Induction of galactose regulated gene expression in yeast |
DE3719213C1 (de) * | 1987-06-09 | 1988-05-19 | Daimler Benz Ag | Bodennahe mehrpolige Stromversorgung fuer spurfuehrbare,gummibereifte,elektrisch antreibbare Fahrzeuge |
US4963483A (en) * | 1987-10-13 | 1990-10-16 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
DE3887082T2 (de) * | 1987-10-29 | 1994-04-28 | Zymogenetics Inc | Verfahren zur Regulierung der Proteinglycosylierung. |
US5135854A (en) * | 1987-10-29 | 1992-08-04 | Zymogenetics, Inc. | Methods of regulating protein glycosylation |
GB8726953D0 (en) * | 1987-11-18 | 1987-12-23 | Delta Biotechnology Ltd | Yeast expression system |
NZ229260A (en) * | 1988-06-03 | 1994-02-25 | Merck & Co Inc | Hepatitis b virus, expression cassette for pre-s domain, host cells and |
DK0414374T3 (da) * | 1989-07-25 | 1998-03-09 | Smithkline Beecham Biolog | Hidtil ukendte antigener og fremgangsmåder til fremstilling deraf |
CA2022108A1 (en) * | 1989-07-31 | 1991-02-01 | Cheryl A. Schulman | Enhanced growth and expression of heterologous proteins in recombinant hosts containing mutations in cell wall and/or plasma membrane biosynthesis |
CA2022109A1 (en) * | 1989-07-31 | 1991-02-01 | Cheryl A. Schulman | Enhanced expression of heterologous proteins in recombinant hosts in a non-growth media |
EP0431679B1 (en) * | 1989-12-05 | 1994-10-19 | Merck & Co. Inc. | Method of stabilizing recombinant hepatitis B virus surface proteins from yeast |
IL101653A0 (en) * | 1991-04-29 | 1992-12-30 | Merck & Co Inc | Multiple hepatitis b virus surface proteins which form particles |
-
1992
- 1992-04-20 IL IL101651A patent/IL101651A0/xx unknown
- 1992-04-24 NZ NZ24248792A patent/NZ242487A/en unknown
- 1992-04-27 SK SK1181-93A patent/SK118193A3/sk unknown
- 1992-04-27 CZ CS932271A patent/CZ282769B6/cs not_active IP Right Cessation
- 1992-04-27 WO PCT/US1992/003472 patent/WO1992019741A1/en active IP Right Grant
- 1992-04-27 PL PL92301163A patent/PL171485B1/pl unknown
- 1992-04-27 HU HU9303064A patent/HUT69149A/hu unknown
- 1992-04-27 CA CA002067290A patent/CA2067290A1/en not_active Abandoned
- 1992-04-28 YU YU45492A patent/YU45492A/sh unknown
- 1992-04-28 MX MX9201970A patent/MX9201970A/es unknown
- 1992-04-28 CN CN92104290A patent/CN1067680A/zh active Pending
- 1992-04-28 ZA ZA923069A patent/ZA923069B/xx unknown
- 1992-04-28 KR KR1019920007142A patent/KR920019373A/ko not_active Application Discontinuation
- 1992-04-28 AU AU15222/92A patent/AU650530B2/en not_active Ceased
- 1992-04-29 DE DE69232541T patent/DE69232541D1/de not_active Expired - Lifetime
- 1992-04-29 AT AT92303883T patent/ATE215987T1/de active
- 1992-04-29 SG SG1996008131A patent/SG55152A1/en unknown
- 1992-04-29 EP EP92303883A patent/EP0516286B1/en not_active Expired - Lifetime
- 1992-04-30 JP JP4155566A patent/JP2637877B2/ja not_active Expired - Fee Related
- 1992-07-01 IE IE138592A patent/IE921385A1/en not_active Application Discontinuation
-
1993
- 1993-03-30 LT LTIP462A patent/LT3367B/lt not_active IP Right Cessation
- 1993-10-21 FI FI934650A patent/FI934650A/fi unknown
- 1993-10-28 NO NO933897A patent/NO933897L/no not_active Application Discontinuation
- 1993-10-29 BG BG98187A patent/BG61700B1/bg unknown
-
1995
- 1995-01-04 US US08/368,287 patent/US5614384A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
MX9201970A (es) | 1992-11-01 |
IL101651A0 (en) | 1992-12-30 |
ATE215987T1 (de) | 2002-04-15 |
FI934650A0 (fi) | 1993-10-21 |
EP0516286B1 (en) | 2002-04-10 |
CZ227193A3 (en) | 1994-04-13 |
CZ282769B6 (cs) | 1997-10-15 |
EP0516286A1 (en) | 1992-12-02 |
NO933897D0 (no) | 1993-10-28 |
FI934650A (fi) | 1993-10-21 |
NO933897L (no) | 1993-10-28 |
JPH06141872A (ja) | 1994-05-24 |
BG98187A (bg) | 1994-06-30 |
WO1992019741A1 (en) | 1992-11-12 |
LTIP462A (en) | 1994-10-25 |
NZ242487A (en) | 1994-07-26 |
AU650530B2 (en) | 1994-06-23 |
LT3367B (en) | 1995-08-25 |
AU1522292A (en) | 1993-03-11 |
ZA923069B (en) | 1992-12-30 |
CA2067290A1 (en) | 1992-10-30 |
IE921385A1 (en) | 1992-11-04 |
US5614384A (en) | 1997-03-25 |
JP2637877B2 (ja) | 1997-08-06 |
BG61700B1 (bg) | 1998-03-31 |
CN1067680A (zh) | 1993-01-06 |
YU45492A (sh) | 1994-06-10 |
DE69232541D1 (de) | 2002-05-16 |
PL171485B1 (pl) | 1997-05-30 |
HU9303064D0 (en) | 1994-03-28 |
SK118193A3 (en) | 1994-03-09 |
KR920019373A (ko) | 1992-11-19 |
HUT69149A (en) | 1995-08-28 |
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