MX9201970A - Proteinas superficiales del virus de la hepatitis b con un contenido reducido del carbohidrato huesped. - Google Patents

Proteinas superficiales del virus de la hepatitis b con un contenido reducido del carbohidrato huesped.

Info

Publication number
MX9201970A
MX9201970A MX9201970A MX9201970A MX9201970A MX 9201970 A MX9201970 A MX 9201970A MX 9201970 A MX9201970 A MX 9201970A MX 9201970 A MX9201970 A MX 9201970A MX 9201970 A MX9201970 A MX 9201970A
Authority
MX
Mexico
Prior art keywords
hbv
surface proteins
virus
particles
carbohydrate
Prior art date
Application number
MX9201970A
Other languages
English (en)
Inventor
Peter J Kniskern
Arpi Hagopian
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of MX9201970A publication Critical patent/MX9201970A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • C07K14/02Hepadnaviridae, e.g. hepatitis B virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
MX9201970A 1991-04-29 1992-04-28 Proteinas superficiales del virus de la hepatitis b con un contenido reducido del carbohidrato huesped. MX9201970A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69292491A 1991-04-29 1991-04-29

Publications (1)

Publication Number Publication Date
MX9201970A true MX9201970A (es) 1992-11-01

Family

ID=24782605

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9201970A MX9201970A (es) 1991-04-29 1992-04-28 Proteinas superficiales del virus de la hepatitis b con un contenido reducido del carbohidrato huesped.

Country Status (25)

Country Link
US (1) US5614384A (es)
EP (1) EP0516286B1 (es)
JP (1) JP2637877B2 (es)
KR (1) KR920019373A (es)
CN (1) CN1067680A (es)
AT (1) ATE215987T1 (es)
AU (1) AU650530B2 (es)
BG (1) BG61700B1 (es)
CA (1) CA2067290A1 (es)
CZ (1) CZ282769B6 (es)
DE (1) DE69232541D1 (es)
FI (1) FI934650A (es)
HU (1) HUT69149A (es)
IE (1) IE921385A1 (es)
IL (1) IL101651A0 (es)
LT (1) LT3367B (es)
MX (1) MX9201970A (es)
NO (1) NO933897L (es)
NZ (1) NZ242487A (es)
PL (1) PL171485B1 (es)
SG (1) SG55152A1 (es)
SK (1) SK118193A3 (es)
WO (1) WO1992019741A1 (es)
YU (1) YU45492A (es)
ZA (1) ZA923069B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533263A3 (en) * 1991-09-20 1994-06-08 Merck & Co Inc A multivalent hepatitis b virus vaccine
WO1995031558A1 (en) * 1994-05-16 1995-11-23 Merck & Co., Inc. Process for producing hbv surface proteins
US6300065B1 (en) * 1996-05-31 2001-10-09 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6696251B1 (en) * 1996-05-31 2004-02-24 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
EP1140155A4 (en) * 1998-12-23 2004-11-03 Merck & Co Inc IMPROVED RECOMBINATION HEPATITIS B ENVELOPE ANTIGEN
KR100604994B1 (ko) * 2004-01-30 2006-07-26 한국생명공학연구원 알파1,6-만노실트랜스퍼라제를 코딩하는 한세눌라폴리모르파 기원의 신규 유전자 및 상기 유전자가 결손된한세눌라 폴리모르파 변이주를 이용한 재조합 당단백질생산 방법
CN111187720A (zh) * 2019-12-27 2020-05-22 深圳康泰生物制品股份有限公司 表达肠道病毒71型抗原的重组汉逊酵母的细胞破碎方法及其在制备手足口病疫苗中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4803164A (en) * 1981-08-31 1989-02-07 Genentech, Inc. Preparation of hepatitis b surface antigen in yeast
US4707542A (en) * 1983-08-22 1987-11-17 Merck & Co., Inc. Immunogenic HbsAg derived from transformed yeast
US4816564A (en) * 1986-01-31 1989-03-28 Merck & Co., Inc. Method for producing hepatitis B virus proteins in yeast
GB8613388D0 (en) * 1986-06-03 1986-07-09 Delta Biotechnology Ltd Induction of galactose regulated gene expression in yeast
DE3719213C1 (de) * 1987-06-09 1988-05-19 Daimler Benz Ag Bodennahe mehrpolige Stromversorgung fuer spurfuehrbare,gummibereifte,elektrisch antreibbare Fahrzeuge
US4963483A (en) * 1987-10-13 1990-10-16 Merck & Co., Inc. Method for producing hepatitis B virus proteins in yeast
US5135854A (en) * 1987-10-29 1992-08-04 Zymogenetics, Inc. Methods of regulating protein glycosylation
EP0314096B1 (en) * 1987-10-29 1994-01-12 Zymogenetics, Inc. Methods of regulating protein glycosylation
GB8726953D0 (en) * 1987-11-18 1987-12-23 Delta Biotechnology Ltd Yeast expression system
NZ229260A (en) * 1988-06-03 1994-02-25 Merck & Co Inc Hepatitis b virus, expression cassette for pre-s domain, host cells and
EP0414374B1 (en) * 1989-07-25 1997-10-08 Smithkline Biologicals S.A. Novel antigens and methods for their preparation
CA2022108A1 (en) * 1989-07-31 1991-02-01 Cheryl A. Schulman Enhanced growth and expression of heterologous proteins in recombinant hosts containing mutations in cell wall and/or plasma membrane biosynthesis
CA2022109A1 (en) * 1989-07-31 1991-02-01 Cheryl A. Schulman Enhanced expression of heterologous proteins in recombinant hosts in a non-growth media
DE69013471T2 (de) * 1989-12-05 1995-03-30 Merck & Co Inc Methode zur Stabilisierung von rekombinanten Hepatitis-B-Virus-Oberflächenproteinen aus Hefe.
IL101653A0 (en) * 1991-04-29 1992-12-30 Merck & Co Inc Multiple hepatitis b virus surface proteins which form particles

Also Published As

Publication number Publication date
CZ282769B6 (cs) 1997-10-15
NO933897D0 (no) 1993-10-28
AU650530B2 (en) 1994-06-23
FI934650A0 (fi) 1993-10-21
SK118193A3 (en) 1994-03-09
JP2637877B2 (ja) 1997-08-06
ATE215987T1 (de) 2002-04-15
SG55152A1 (en) 1998-12-21
HU9303064D0 (en) 1994-03-28
DE69232541D1 (de) 2002-05-16
IL101651A0 (en) 1992-12-30
PL171485B1 (pl) 1997-05-30
NO933897L (no) 1993-10-28
EP0516286A1 (en) 1992-12-02
US5614384A (en) 1997-03-25
HUT69149A (en) 1995-08-28
BG98187A (bg) 1994-06-30
KR920019373A (ko) 1992-11-19
CN1067680A (zh) 1993-01-06
CZ227193A3 (en) 1994-04-13
YU45492A (sh) 1994-06-10
BG61700B1 (bg) 1998-03-31
EP0516286B1 (en) 2002-04-10
ZA923069B (en) 1992-12-30
FI934650A (fi) 1993-10-21
LTIP462A (en) 1994-10-25
JPH06141872A (ja) 1994-05-24
WO1992019741A1 (en) 1992-11-12
NZ242487A (en) 1994-07-26
AU1522292A (en) 1993-03-11
IE921385A1 (en) 1992-11-04
LT3367B (en) 1995-08-25
CA2067290A1 (en) 1992-10-30

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