SG48229A1 - Monoclonal antibodies to new factor viii coagulant polypeptides - Google Patents

Monoclonal antibodies to new factor viii coagulant polypeptides

Info

Publication number
SG48229A1
SG48229A1 SG1996008094A SG1996008094A SG48229A1 SG 48229 A1 SG48229 A1 SG 48229A1 SG 1996008094 A SG1996008094 A SG 1996008094A SG 1996008094 A SG1996008094 A SG 1996008094A SG 48229 A1 SG48229 A1 SG 48229A1
Authority
SG
Singapore
Prior art keywords
polypeptides
reacts
factor viii
those
react
Prior art date
Application number
SG1996008094A
Other languages
English (en)
Inventor
Theodore S Zimmerman
Carol A Fulcher
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27046849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG48229(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of SG48229A1 publication Critical patent/SG48229A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
SG1996008094A 1983-03-31 1984-04-02 Monoclonal antibodies to new factor viii coagulant polypeptides SG48229A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48110583A 1983-03-31 1983-03-31
US55650883A 1983-11-30 1983-11-30

Publications (1)

Publication Number Publication Date
SG48229A1 true SG48229A1 (en) 1998-04-17

Family

ID=27046849

Family Applications (2)

Application Number Title Priority Date Filing Date
SG1996003792A SG49675A1 (en) 1983-03-31 1984-04-02 New factor VIII coagulant polypeptides and monoclonal antibodies to them
SG1996008094A SG48229A1 (en) 1983-03-31 1984-04-02 Monoclonal antibodies to new factor viii coagulant polypeptides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG1996003792A SG49675A1 (en) 1983-03-31 1984-04-02 New factor VIII coagulant polypeptides and monoclonal antibodies to them

Country Status (12)

Country Link
EP (3) EP0770396A3 (fi)
JP (2) JPH0829089B2 (fi)
AT (2) ATE155490T1 (fi)
AU (1) AU572128B2 (fi)
CA (1) CA1341506C (fi)
DE (2) DE3486453T2 (fi)
DK (2) DK172036B1 (fi)
FI (1) FI841281A (fi)
IE (2) IE80858B1 (fi)
NO (1) NO167533C (fi)
SG (2) SG49675A1 (fi)
ZA (1) ZA842418B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
US4716117A (en) * 1984-10-26 1987-12-29 Chiron Corporation Monoclonal antibodies to factor VIIIC
DK13485A (da) * 1984-01-12 1985-07-13 Chiron Corp Hybridomacellelinie og monoklonalt antistof opnaaet ved hjaelp af en saadan cellelinie
US7138505B1 (en) 1984-01-12 2006-11-21 Novartis Vaccines And Diagnostics, Inc. Factor VIII:C nucleic acid molecules
US5004804A (en) * 1984-01-12 1991-04-02 Nordisk Gentofte Method and composition for preparation of factor VIIIC
DE3586402T3 (de) * 1984-01-12 2004-12-23 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Proteinzusammensetzung mit Koagulations-wirkung und Verfahren zu ihrer Herstellung.
US5045455A (en) * 1984-01-12 1991-09-03 Chiron Corporation Factor VIII:C cDNA cloning and expression
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
FI86885C (fi) * 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
EP0272304B1 (en) * 1986-06-24 1994-01-26 Novo Nordisk A/S A process for producing a coagulation active complex of factor viii fragments
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
EP0294910B1 (en) 1987-06-12 1996-09-11 Immuno Ag Novel proteins with factor VIII activity, process for their preparation using genetically engineered cells and pharmaceutical compositions containing them
IL88309A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides for use in the purification of factor viii
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
WO1995003332A1 (en) * 1993-07-23 1995-02-02 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
JP5149470B2 (ja) 1999-02-22 2013-02-20 バクスター・インターナショナル・インコーポレイテッド 新規のアルブミンを含有していない第ｖｉｉｉ因子処方物
EP1418810A4 (en) 2001-08-03 2006-08-02 Us Gov Health & Human Serv TREATMENT OF HEMOPHILIA ORAL
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
BRPI1105317A2 (pt) 2011-01-24 2013-04-30 Fundacco Hemoct De Ribeirco Preto produÇço estÁvel e em larga escala de fviii humano em linhagem celular humana sk-hep-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364937A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human T cell antigen and methods of preparing same
US4364936A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human monocyte antigen and methods of preparing same
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C

Also Published As

Publication number Publication date
ATE155490T1 (de) 1997-08-15
IE840788L (en) 1984-09-30
IE960783L (en) 1984-09-30
DK174984A (da) 1984-10-01
DK174984D0 (da) 1984-03-30
DE3486453D1 (de) 1997-08-21
DE3486453T2 (de) 1998-02-26
SG49675A1 (en) 1998-06-15
EP0770396A2 (en) 1997-05-02
ATE135400T1 (de) 1996-03-15
EP0561427A1 (en) 1993-09-22
AU572128B2 (en) 1988-05-05
NO167533C (no) 1991-11-13
DE3486423T3 (de) 2001-02-08
AU2627284A (en) 1984-10-04
CA1341506C (en) 2006-06-06
FI841281A0 (fi) 1984-03-30
NO167533B (no) 1991-08-05
IE80638B1 (en) 1998-10-21
JPH0829089B2 (ja) 1996-03-27
IE80858B1 (en) 1999-04-21
ZA842418B (en) 1984-11-28
FI841281A (fi) 1984-10-01
EP0123945B2 (en) 2000-04-19
DK50497A (da) 1997-05-02
JPS59184130A (ja) 1984-10-19
EP0123945A1 (en) 1984-11-07
DK172036B1 (da) 1997-09-22
DE3486423T2 (de) 1996-09-19
DE3486423D1 (de) 1996-04-18
JPH0638790A (ja) 1994-02-15
EP0561427B1 (en) 1997-07-16
NO841277L (no) 1984-10-01
EP0770396A3 (en) 1997-07-23
EP0123945B1 (en) 1996-03-13

Similar Documents

Publication Publication Date Title
AU572128B2 (en) New factor viii, coagulant polypeptides and monoclonal antibodies
IL73883A (en) Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
EP0212403A3 (en) Monoclonal antibodies to mucin-like human differentiation antigens
DE3689734D1 (de) Gereinigter immunoglobulinbezüglicher Faktor, monoklonale Antikörper, Hybridoma-Zellinien, Verfahren und Verwendungen.
AU1582495A (en) Recombinant baculovirus and use thereof in the production of monoclonal antibodies
ATE110084T1 (de) Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung.
DE3581288D1 (de) Antileishmania monoklonale antikoerper, diese antikoerper ausscheidende hybridomas, von diesen antikoerpern erkannte leishmaniaantigene, verfahren zur herstellung und verwendung von diesen monoklonalen antikoerpern und antigenen.
EP0102601A3 (en) Monoclonal antibody, a process for its production and the use of this monoclonal antibody
DE3580382D1 (de) Monoklonale antikoerper gegen alpha-2 interferon und hybridomas, die solche antikoerper produzieren.
ES8503371A1 (es) Procedimiento para preparar nuevos anticuerpos de igg de raton con especificidad anti-interferon de humano
DK105085D0 (da) Monoklonalt antistof samt hybridom-cellelinie, der udskiller dette
ATE62709T1 (de) Monoklonale antikoerper.
EP0179576A3 (en) Monoclonal antibody
AU590688B2 (en) Monoclonal antibody to HLI and its use for purifying HLI
EP0328248A3 (en) Monoclonal antibodies against a follicle-stimulating hormone
ATE56617T1 (de) Anti-urokinase monoklonaler antikoerper, seine herstellung und verwendung.
IL73475A (en) Monoclonal antibody to propranolol and hybridoma cell line producing it
EP0089771A3 (en) Atcc hb8116 and its monoclonal anti-h-y antibody, hyclonalan
BG46674A1 (en) Hybridom cell line mus musculus vsp- 1e7 secreting monoclonal antibodies against virus of classical plague
NZ228194A (en) Monoclonal antibodies which bind to the n-terminal peptide sequence of the betasubunit of human haemoglobiin
IE831500L (en) Hybridoma cell lines and monoclonal antibodies to¹theophylline
EP0287012A3 (en) Anti-r-binder monoclonal antibody, process for preparing the same and application of the same
EP0349258A3 (en) Method of determining the differentiation of a human t-cell
ATE64616T1 (de) Oncofetal spezifische monoklonale antikoerper, deren herstellung und verwendung.
IE832835L (en) Monoclonal antibodies related to dna from patients with¹systemic hupus erythematoses