SG2014013676A - Therapeutics using adipose cells and cell secretions - Google Patents
Therapeutics using adipose cells and cell secretionsInfo
- Publication number
- SG2014013676A SG2014013676A SG2014013676A SG2014013676A SG2014013676A SG 2014013676 A SG2014013676 A SG 2014013676A SG 2014013676 A SG2014013676 A SG 2014013676A SG 2014013676 A SG2014013676 A SG 2014013676A SG 2014013676 A SG2014013676 A SG 2014013676A
- Authority
- SG
- Singapore
- Prior art keywords
- therapeutics
- adipose cells
- cell secretions
- secretions
- cell
- Prior art date
Links
- 210000001789 adipocyte Anatomy 0.000 title 1
- 210000004027 cell Anatomy 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000028327 secretion Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011903938A AU2011903938A0 (en) | 2011-09-23 | Therapeutic methods and compositions | |
| AU2012901350A AU2012901350A0 (en) | 2012-04-04 | Therapeutic methods and compositions | |
| AU2012903646A AU2012903646A0 (en) | 2012-08-23 | Therapeutic methods and compositions | |
| PCT/AU2012/001140 WO2013040649A1 (en) | 2011-09-23 | 2012-09-21 | Therapeutics using adipose cells and cell secretions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG2014013676A true SG2014013676A (en) | 2014-05-29 |
Family
ID=47913679
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2014013676A SG2014013676A (en) | 2011-09-23 | 2012-09-21 | Therapeutics using adipose cells and cell secretions |
| SG10201606745XA SG10201606745XA (en) | 2011-09-23 | 2012-09-21 | Therapeutics using adipose cells and cell secretions |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201606745XA SG10201606745XA (en) | 2011-09-23 | 2012-09-21 | Therapeutics using adipose cells and cell secretions |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10111909B2 (enExample) |
| EP (3) | EP3546569B1 (enExample) |
| JP (5) | JP6162123B2 (enExample) |
| AU (1) | AU2012313352B2 (enExample) |
| CA (1) | CA2885487C (enExample) |
| DK (2) | DK3546569T3 (enExample) |
| ES (2) | ES2721180T3 (enExample) |
| SG (2) | SG2014013676A (enExample) |
| WO (1) | WO2013040649A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
| US20140286911A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
| DK3546569T3 (da) * | 2011-09-23 | 2021-07-12 | Cell Ideas Pty Ltd | Terapeutiske midler med anvendelse af fedtceller og cellesekreter |
| JP2023002772A (ja) * | 2011-09-23 | 2023-01-10 | レジニアス リミテッド | 脂肪細胞および細胞分泌物を使用する治療 |
| AU2013204930C1 (en) * | 2012-09-26 | 2015-01-22 | Cell Ideas Pty Ltd | Therapeutics using multiple injections of cells |
| WO2014078705A1 (en) | 2012-11-15 | 2014-05-22 | Allosource | Minced cartilage systems and methods |
| WO2014100857A1 (en) | 2012-12-24 | 2014-07-03 | Cell Ideas Pty Ltd | Vaccines for the treatment of cancer and compositions for enhancing vaccine efficacy |
| EP2958523B1 (en) * | 2013-02-22 | 2020-04-22 | AlloSource | Cartilage mosaic compositions and methods |
| US9168140B2 (en) | 2013-03-15 | 2015-10-27 | Allosource | Perforated osteochondral allograft compositions |
| JP2016523083A (ja) * | 2013-06-19 | 2016-08-08 | スパイナルサイト, エルエルシー | 軟骨細胞適用のための脂肪細胞 |
| US20160245825A1 (en) * | 2013-10-04 | 2016-08-25 | Cell Ideas Pty Ltd | Biomarkers for Cell Therapy |
| JP2018501241A (ja) * | 2014-12-19 | 2018-01-18 | セル・アイディアズ・ピーティーワイ・リミテッド | 改良された細胞療法 |
| AU2016321448B2 (en) | 2015-09-08 | 2023-02-02 | Cell Ideas Pty Ltd | Cell expansion methods and therapeutic compositions |
| EP3381458B1 (en) * | 2015-11-24 | 2023-06-07 | Rohto Pharmaceutical Co., Ltd. | Therapeutic agent for liver disease containing stromal cells derived from adipose tissue and method for producing the same |
| WO2018002930A1 (en) | 2016-06-30 | 2018-01-04 | Stem Cell Medicine Ltd. | Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells |
| CA3062123A1 (en) | 2017-05-15 | 2018-11-22 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with adipose-derived stem cells |
| CN110709091A (zh) | 2017-05-15 | 2020-01-17 | 干细胞医药有限公司 | 使用长效格拉替雷和脂肪源性干细胞治疗多发性硬化症 |
| MX2019014426A (es) * | 2017-10-02 | 2020-02-05 | Fukuoka Hirotaro | Composicion farmaceutica para usarse en la mejora de la calidad del cuero cabelludo y la piel, de la cicatrizacion de heridas o mejora de la calidad del cabello. |
| AU2019287353A1 (en) * | 2018-06-15 | 2021-02-04 | NextPhase Therapeutics, Inc. | Pharmaceutical composition for dermatology and uses thereof |
| CN112839667A (zh) * | 2018-08-14 | 2021-05-25 | 国立研究开发法人国立国际医疗研究中心 | 褐色脂肪细胞上清、其制备法及使用 |
| JP7429032B2 (ja) * | 2019-12-24 | 2024-02-07 | 学校法人順天堂 | 間質性肺炎モデル非ヒト動物の作製方法 |
| JP6826744B1 (ja) * | 2020-07-17 | 2021-02-10 | 医療法人Yanaga CLinic | 成熟脂肪細胞含有組成物の製造方法 |
| CN114452303B (zh) * | 2020-11-10 | 2025-05-30 | 上海萨美细胞技术有限公司 | 无细胞脂肪提取液对关节炎的治疗用途 |
| IT202100003062A1 (it) * | 2021-02-11 | 2022-08-11 | Gaia Margiotta | "processo di crioconservazione di tessuto adiposo" |
| JP7057006B1 (ja) * | 2021-04-12 | 2022-04-19 | 医療法人社団サカイクリニック62 | 歯周組織用製剤及びそれを含むキット |
| CN115521908A (zh) * | 2022-10-24 | 2022-12-27 | 潍坊天创生物科技有限公司 | 一种脂肪间充质干细胞的体外培养及外泌体的分离纯化方法 |
| AU2023415952A1 (en) | 2022-12-27 | 2025-07-24 | AVITA Medical Americas, LLC | System for automated preparation of a regenerative epidermal suspension and related methods of use |
| CN118105463B (zh) * | 2024-02-27 | 2025-05-30 | 上海萨美细胞技术有限公司 | 脂肪脱细胞活性蛋白在抗阿尔兹海默症中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6037175A (en) | 1996-03-12 | 2000-03-14 | The University Of South Florida | Method and media for enhancing cryopreservation of cells |
| US7078232B2 (en) * | 1999-08-19 | 2006-07-18 | Artecel, Inc. | Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof |
| US20030054331A1 (en) | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| CA2466880A1 (en) | 2001-11-09 | 2003-05-15 | Artecel Sciences, Inc. | Methods and compositions for the use of stromal cells to support embryonic and adult stem cells |
| KR101083454B1 (ko) * | 2001-12-07 | 2011-11-16 | 사이토리 테라퓨틱스, 인크. | 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법 |
| JP2007508018A (ja) * | 2003-10-08 | 2007-04-05 | べト−ステム インコーポレイテッド | 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット |
| US8715733B2 (en) * | 2004-07-23 | 2014-05-06 | DePuy Synthes Products, LLC | Enhanced adipose tissue |
| US20100092432A1 (en) | 2006-08-08 | 2010-04-15 | Takenori Ozaki | Cell preparation containing multipotential stem cells originating in fat tissue |
| US8835170B2 (en) * | 2006-10-06 | 2014-09-16 | University Of Virginia Patent Foundation | Methods and compositions useful for diabetic wound healing |
| AU2009227022B2 (en) | 2008-03-19 | 2014-07-03 | Cryo-Save Ag | Improved cryopreservation of adipose tissue for the isolation of mesenchymal stem cells |
| WO2009152084A2 (en) | 2008-06-11 | 2009-12-17 | Cell4Vet Llc | Adipose tissue-derived stem cells for veterinary use |
| AU2009201915C1 (en) | 2008-08-22 | 2015-02-26 | Regeneus Ltd | Therapeutic methods |
| ES2479621T3 (es) * | 2009-04-28 | 2014-07-24 | Anterogen Co., Ltd. | Composición de células madre estromales derivadas de tejido adiposo autólogo y alogénico destinada al tratamiento de fístulas |
| US20120201791A1 (en) * | 2009-10-15 | 2012-08-09 | Tai June Yoo | Methods of treating diseases or conditions using mesenchymal stem cells |
| CN103596577B (zh) * | 2011-03-15 | 2017-02-15 | 赛尔爱迪尔私人有限公司 | 包含脂肪组织来源的分泌物的组合物在制备用于局部治疗或预防个体中痤疮的药物中的用途 |
| DK3546569T3 (da) * | 2011-09-23 | 2021-07-12 | Cell Ideas Pty Ltd | Terapeutiske midler med anvendelse af fedtceller og cellesekreter |
-
2012
- 2012-09-21 DK DK19153401.5T patent/DK3546569T3/da active
- 2012-09-21 DK DK12833860.5T patent/DK2744892T3/en active
- 2012-09-21 SG SG2014013676A patent/SG2014013676A/en unknown
- 2012-09-21 EP EP19153401.5A patent/EP3546569B1/en active Active
- 2012-09-21 EP EP12833860.5A patent/EP2744892B1/en active Active
- 2012-09-21 US US14/342,479 patent/US10111909B2/en active Active
- 2012-09-21 ES ES12833860T patent/ES2721180T3/es active Active
- 2012-09-21 JP JP2014531048A patent/JP6162123B2/ja active Active
- 2012-09-21 ES ES19153401T patent/ES2880084T3/es active Active
- 2012-09-21 SG SG10201606745XA patent/SG10201606745XA/en unknown
- 2012-09-21 AU AU2012313352A patent/AU2012313352B2/en not_active Ceased
- 2012-09-21 EP EP21165734.1A patent/EP3868871A1/en not_active Withdrawn
- 2012-09-21 CA CA2885487A patent/CA2885487C/en active Active
- 2012-09-21 WO PCT/AU2012/001140 patent/WO2013040649A1/en not_active Ceased
-
2017
- 2017-06-14 JP JP2017116648A patent/JP6839038B2/ja not_active Expired - Fee Related
-
2018
- 2018-09-19 US US16/135,700 patent/US10660921B2/en not_active Expired - Fee Related
-
2019
- 2019-05-13 JP JP2019090715A patent/JP6912512B2/ja active Active
-
2020
- 2020-04-20 US US16/853,569 patent/US20200261510A1/en not_active Abandoned
-
2021
- 2021-07-05 JP JP2021111459A patent/JP7022863B2/ja not_active Expired - Fee Related
- 2021-12-01 JP JP2021195358A patent/JP2022033865A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201606745XA (en) | 2016-10-28 |
| EP3546569A1 (en) | 2019-10-02 |
| DK3546569T3 (da) | 2021-07-12 |
| CA2885487C (en) | 2021-11-16 |
| ES2880084T3 (es) | 2021-11-23 |
| JP2014527821A (ja) | 2014-10-23 |
| US10660921B2 (en) | 2020-05-26 |
| JP2022033865A (ja) | 2022-03-02 |
| EP2744892A1 (en) | 2014-06-25 |
| DK2744892T3 (en) | 2019-04-23 |
| JP7022863B2 (ja) | 2022-02-18 |
| JP6912512B2 (ja) | 2021-08-04 |
| JP6839038B2 (ja) | 2021-03-03 |
| WO2013040649A1 (en) | 2013-03-28 |
| EP2744892B1 (en) | 2019-03-20 |
| JP6162123B2 (ja) | 2017-07-12 |
| AU2012313352A1 (en) | 2013-05-02 |
| AU2012313352B2 (en) | 2015-07-02 |
| EP3546569B1 (en) | 2021-06-16 |
| AU2012313352A9 (en) | 2013-09-26 |
| CA2885487A1 (en) | 2013-03-28 |
| EP3868871A1 (en) | 2021-08-25 |
| US20190015455A1 (en) | 2019-01-17 |
| US10111909B2 (en) | 2018-10-30 |
| US20140234272A1 (en) | 2014-08-21 |
| EP2744892A4 (en) | 2015-05-20 |
| JP2021155461A (ja) | 2021-10-07 |
| JP2019142971A (ja) | 2019-08-29 |
| JP2017193566A (ja) | 2017-10-26 |
| ES2721180T3 (es) | 2019-07-29 |
| US20200261510A1 (en) | 2020-08-20 |
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