AU2012313352B2 - Stem cells and secretions for treatment of inflammatory conditions - Google Patents

Stem cells and secretions for treatment of inflammatory conditions Download PDF

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Publication number
AU2012313352B2
AU2012313352B2 AU2012313352A AU2012313352A AU2012313352B2 AU 2012313352 B2 AU2012313352 B2 AU 2012313352B2 AU 2012313352 A AU2012313352 A AU 2012313352A AU 2012313352 A AU2012313352 A AU 2012313352A AU 2012313352 B2 AU2012313352 B2 AU 2012313352B2
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AU
Australia
Prior art keywords
adipose tissue
cells
secretions
derived
derived cell
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Ceased
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AU2012313352A
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English (en)
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AU2012313352A1 (en
AU2012313352A9 (en
Inventor
Richard Lilischkis
Graham Vesey
Rebecca Anne WEBSTER
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Cell Ideas Pty Ltd
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Cell Ideas Pty Ltd
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Priority claimed from AU2011903938A external-priority patent/AU2011903938A0/en
Priority to AU2013205128A priority Critical patent/AU2013205128A1/en
Priority to AU2012313352A priority patent/AU2012313352B2/en
Application filed by Cell Ideas Pty Ltd filed Critical Cell Ideas Pty Ltd
Publication of AU2012313352A1 publication Critical patent/AU2012313352A1/en
Publication of AU2012313352A9 publication Critical patent/AU2012313352A9/en
Publication of AU2012313352B2 publication Critical patent/AU2012313352B2/en
Application granted granted Critical
Priority to AU2015230871A priority patent/AU2015230871A1/en
Priority to AU2017245310A priority patent/AU2017245310A1/en
Priority to AU2019203058A priority patent/AU2019203058A1/en
Priority to AU2020257078A priority patent/AU2020257078B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
AU2012313352A 2011-09-23 2012-09-21 Stem cells and secretions for treatment of inflammatory conditions Ceased AU2012313352B2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2013205128A AU2013205128A1 (en) 2011-09-23 2012-09-21 Therapeutics using adipose cells and cell secretions
AU2012313352A AU2012313352B2 (en) 2011-09-23 2012-09-21 Stem cells and secretions for treatment of inflammatory conditions
AU2015230871A AU2015230871A1 (en) 2011-09-23 2015-09-29 Stem cells and secretions for treatment of inflammatory conditions
AU2017245310A AU2017245310A1 (en) 2011-09-23 2017-10-10 Stem cells and secretions for treatment of inflammatory conditions
AU2019203058A AU2019203058A1 (en) 2011-09-23 2019-04-30 Stem cells and secretions for treatment of inflammatory conditions
AU2020257078A AU2020257078B2 (en) 2011-09-23 2020-10-21 Stem cells and secretions for treatment of inflammatory conditions

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
AU2011903938A AU2011903938A0 (en) 2011-09-23 Therapeutic methods and compositions
AU2011903938 2011-09-23
AU2012901350A AU2012901350A0 (en) 2012-04-04 Therapeutic methods and compositions
AU2012901350 2012-04-04
AU2012903646 2012-08-23
AU2012903646A AU2012903646A0 (en) 2012-08-23 Therapeutic methods and compositions
AU2012313352A AU2012313352B2 (en) 2011-09-23 2012-09-21 Stem cells and secretions for treatment of inflammatory conditions
PCT/AU2012/001140 WO2013040649A1 (en) 2011-09-23 2012-09-21 Therapeutics using adipose cells and cell secretions

Related Child Applications (4)

Application Number Title Priority Date Filing Date
AU2013205128A Division AU2013205128A1 (en) 2011-09-23 2012-09-21 Therapeutics using adipose cells and cell secretions
AU2013203073A Division AU2013203073B2 (en) 2011-09-23 2013-04-09 Stem cell secretions for topical treatment of skin conditions
AU2013203072A Division AU2013203072B2 (en) 2011-09-23 2013-04-09 Therapeutic methods and compositions comprising cells and secretions
AU2015230871A Division AU2015230871A1 (en) 2011-09-23 2015-09-29 Stem cells and secretions for treatment of inflammatory conditions

Publications (3)

Publication Number Publication Date
AU2012313352A1 AU2012313352A1 (en) 2013-05-02
AU2012313352A9 AU2012313352A9 (en) 2013-09-26
AU2012313352B2 true AU2012313352B2 (en) 2015-07-02

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AU2012313352A Ceased AU2012313352B2 (en) 2011-09-23 2012-09-21 Stem cells and secretions for treatment of inflammatory conditions

Country Status (9)

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US (3) US10111909B2 (enExample)
EP (3) EP2744892B1 (enExample)
JP (5) JP6162123B2 (enExample)
AU (1) AU2012313352B2 (enExample)
CA (1) CA2885487C (enExample)
DK (2) DK2744892T3 (enExample)
ES (2) ES2721180T3 (enExample)
SG (2) SG10201606745XA (enExample)
WO (1) WO2013040649A1 (enExample)

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CN108289915A (zh) * 2015-11-24 2018-07-17 日本乐敦制药株式会社 包含脂肪组织来源基质细胞的肝病治疗剂及其制造方法
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KR20210021358A (ko) * 2018-06-15 2021-02-25 파르도 루이스 마리나스 약제학적 피부과 조성물 및 그 용도
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JP7429032B2 (ja) * 2019-12-24 2024-02-07 学校法人順天堂 間質性肺炎モデル非ヒト動物の作製方法
JP6826744B1 (ja) * 2020-07-17 2021-02-10 医療法人Ｙａｎａｇａ ＣＬｉｎｉｃ 成熟脂肪細胞含有組成物の製造方法
CN114452303B (zh) * 2020-11-10 2025-05-30 上海萨美细胞技术有限公司 无细胞脂肪提取液对关节炎的治疗用途
IT202100003062A1 (it) * 2021-02-11 2022-08-11 Gaia Margiotta "processo di crioconservazione di tessuto adiposo"
JP7057006B1 (ja) * 2021-04-12 2022-04-19 医療法人社団サカイクリニック６２ 歯周組織用製剤及びそれを含むキット
US12636408B2 (en) 2021-08-12 2026-05-26 Britecyte Inc. Adipose compositions and methods of use thereof
CN115521908A (zh) * 2022-10-24 2022-12-27 潍坊天创生物科技有限公司 一种脂肪间充质干细胞的体外培养及外泌体的分离纯化方法
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Also Published As

Publication number Publication date
JP2022033865A (ja) 2022-03-02
ES2880084T3 (es) 2021-11-23
WO2013040649A1 (en) 2013-03-28
SG10201606745XA (en) 2016-10-28
CA2885487C (en) 2021-11-16
ES2721180T3 (es) 2019-07-29
DK3546569T3 (da) 2021-07-12
US10660921B2 (en) 2020-05-26
EP3546569A1 (en) 2019-10-02
EP2744892A1 (en) 2014-06-25
US10111909B2 (en) 2018-10-30
JP6162123B2 (ja) 2017-07-12
JP2021155461A (ja) 2021-10-07
JP2019142971A (ja) 2019-08-29
JP7022863B2 (ja) 2022-02-18
JP6912512B2 (ja) 2021-08-04
EP3546569B1 (en) 2021-06-16
US20140234272A1 (en) 2014-08-21
US20190015455A1 (en) 2019-01-17
AU2012313352A1 (en) 2013-05-02
JP6839038B2 (ja) 2021-03-03
CA2885487A1 (en) 2013-03-28
EP2744892B1 (en) 2019-03-20
EP2744892A4 (en) 2015-05-20
JP2014527821A (ja) 2014-10-23
JP2017193566A (ja) 2017-10-26
AU2012313352A9 (en) 2013-09-26
EP3868871A1 (en) 2021-08-25
US20200261510A1 (en) 2020-08-20
DK2744892T3 (en) 2019-04-23
SG2014013676A (en) 2014-05-29

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