JP6162123B2 - 脂肪細胞および細胞分泌物を使用する治療 - Google Patents

脂肪細胞および細胞分泌物を使用する治療 Download PDF

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JP6162123B2
JP6162123B2 JP2014531048A JP2014531048A JP6162123B2 JP 6162123 B2 JP6162123 B2 JP 6162123B2 JP 2014531048 A JP2014531048 A JP 2014531048A JP 2014531048 A JP2014531048 A JP 2014531048A JP 6162123 B2 JP6162123 B2 JP 6162123B2
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adipose tissue
cells
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derived cell
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JP2014527821A5 (enExample
JP2014527821A (ja
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グラハム・ヴェシー
レベッカ・アン・ウェブスター
リチャード・リリシュキス
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セル・アイディアズ・ピーティーワイ・リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
JP2014531048A 2011-09-23 2012-09-21 脂肪細胞および細胞分泌物を使用する治療 Active JP6162123B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
AU2011903938A AU2011903938A0 (en) 2011-09-23 Therapeutic methods and compositions
AU2011903938 2011-09-23
AU2012901350 2012-04-04
AU2012901350A AU2012901350A0 (en) 2012-04-04 Therapeutic methods and compositions
AU2012903646A AU2012903646A0 (en) 2012-08-23 Therapeutic methods and compositions
AU2012903646 2012-08-23
PCT/AU2012/001140 WO2013040649A1 (en) 2011-09-23 2012-09-21 Therapeutics using adipose cells and cell secretions

Related Child Applications (1)

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JP2017116648A Division JP6839038B2 (ja) 2011-09-23 2017-06-14 脂肪細胞および細胞分泌物を使用する治療

Publications (3)

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JP2014527821A JP2014527821A (ja) 2014-10-23
JP2014527821A5 JP2014527821A5 (enExample) 2015-11-12
JP6162123B2 true JP6162123B2 (ja) 2017-07-12

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JP2014531048A Active JP6162123B2 (ja) 2011-09-23 2012-09-21 脂肪細胞および細胞分泌物を使用する治療
JP2017116648A Expired - Fee Related JP6839038B2 (ja) 2011-09-23 2017-06-14 脂肪細胞および細胞分泌物を使用する治療
JP2019090715A Active JP6912512B2 (ja) 2011-09-23 2019-05-13 脂肪細胞および細胞分泌物を使用する治療
JP2021111459A Expired - Fee Related JP7022863B2 (ja) 2011-09-23 2021-07-05 脂肪細胞および細胞分泌物を使用する治療
JP2021195358A Pending JP2022033865A (ja) 2011-09-23 2021-12-01 脂肪細胞および細胞分泌物を使用する治療

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JP2017116648A Expired - Fee Related JP6839038B2 (ja) 2011-09-23 2017-06-14 脂肪細胞および細胞分泌物を使用する治療
JP2019090715A Active JP6912512B2 (ja) 2011-09-23 2019-05-13 脂肪細胞および細胞分泌物を使用する治療
JP2021111459A Expired - Fee Related JP7022863B2 (ja) 2011-09-23 2021-07-05 脂肪細胞および細胞分泌物を使用する治療
JP2021195358A Pending JP2022033865A (ja) 2011-09-23 2021-12-01 脂肪細胞および細胞分泌物を使用する治療

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US (3) US10111909B2 (enExample)
EP (3) EP3546569B1 (enExample)
JP (5) JP6162123B2 (enExample)
AU (1) AU2012313352B2 (enExample)
CA (1) CA2885487C (enExample)
DK (2) DK3546569T3 (enExample)
ES (2) ES2721180T3 (enExample)
SG (2) SG2014013676A (enExample)
WO (1) WO2013040649A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021155461A (ja) * 2011-09-23 2021-10-07 レジニアス リミテッド 脂肪細胞および細胞分泌物を使用する治療

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
JP2023002772A (ja) * 2011-09-23 2023-01-10 レジニアス リミテッド 脂肪細胞および細胞分泌物を使用する治療
AU2013204930C1 (en) * 2012-09-26 2015-01-22 Cell Ideas Pty Ltd Therapeutics using multiple injections of cells
WO2014078705A1 (en) 2012-11-15 2014-05-22 Allosource Minced cartilage systems and methods
WO2014100857A1 (en) 2012-12-24 2014-07-03 Cell Ideas Pty Ltd Vaccines for the treatment of cancer and compositions for enhancing vaccine efficacy
EP2958523B1 (en) * 2013-02-22 2020-04-22 AlloSource Cartilage mosaic compositions and methods
US9168140B2 (en) 2013-03-15 2015-10-27 Allosource Perforated osteochondral allograft compositions
JP2016523083A (ja) * 2013-06-19 2016-08-08 スパイナルサイト， エルエルシー 軟骨細胞適用のための脂肪細胞
US20160245825A1 (en) * 2013-10-04 2016-08-25 Cell Ideas Pty Ltd Biomarkers for Cell Therapy
JP2018501241A (ja) * 2014-12-19 2018-01-18 セル・アイディアズ・ピーティーワイ・リミテッド 改良された細胞療法
AU2016321448B2 (en) 2015-09-08 2023-02-02 Cell Ideas Pty Ltd Cell expansion methods and therapeutic compositions
EP3381458B1 (en) * 2015-11-24 2023-06-07 Rohto Pharmaceutical Co., Ltd. Therapeutic agent for liver disease containing stromal cells derived from adipose tissue and method for producing the same
WO2018002930A1 (en) 2016-06-30 2018-01-04 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
CA3062123A1 (en) 2017-05-15 2018-11-22 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with adipose-derived stem cells
CN110709091A (zh) 2017-05-15 2020-01-17 干细胞医药有限公司 使用长效格拉替雷和脂肪源性干细胞治疗多发性硬化症
MX2019014426A (es) * 2017-10-02 2020-02-05 Fukuoka Hirotaro Composicion farmaceutica para usarse en la mejora de la calidad del cuero cabelludo y la piel, de la cicatrizacion de heridas o mejora de la calidad del cabello.
AU2019287353A1 (en) * 2018-06-15 2021-02-04 NextPhase Therapeutics, Inc. Pharmaceutical composition for dermatology and uses thereof
CN112839667A (zh) * 2018-08-14 2021-05-25 国立研究开发法人国立国际医疗研究中心 褐色脂肪细胞上清、其制备法及使用
JP7429032B2 (ja) * 2019-12-24 2024-02-07 学校法人順天堂 間質性肺炎モデル非ヒト動物の作製方法
JP6826744B1 (ja) * 2020-07-17 2021-02-10 医療法人Ｙａｎａｇａ ＣＬｉｎｉｃ 成熟脂肪細胞含有組成物の製造方法
CN114452303B (zh) * 2020-11-10 2025-05-30 上海萨美细胞技术有限公司 无细胞脂肪提取液对关节炎的治疗用途
IT202100003062A1 (it) * 2021-02-11 2022-08-11 Gaia Margiotta "processo di crioconservazione di tessuto adiposo"
JP7057006B1 (ja) * 2021-04-12 2022-04-19 医療法人社団サカイクリニック６２ 歯周組織用製剤及びそれを含むキット
CN115521908A (zh) * 2022-10-24 2022-12-27 潍坊天创生物科技有限公司 一种脂肪间充质干细胞的体外培养及外泌体的分离纯化方法
AU2023415952A1 (en) 2022-12-27 2025-07-24 AVITA Medical Americas, LLC System for automated preparation of a regenerative epidermal suspension and related methods of use
CN118105463B (zh) * 2024-02-27 2025-05-30 上海萨美细胞技术有限公司 脂肪脱细胞活性蛋白在抗阿尔兹海默症中的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037175A (en) 1996-03-12 2000-03-14 The University Of South Florida Method and media for enhancing cryopreservation of cells
US7078232B2 (en) * 1999-08-19 2006-07-18 Artecel, Inc. Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
US20030054331A1 (en) 2001-09-14 2003-03-20 Stemsource, Inc. Preservation of non embryonic cells from non hematopoietic tissues
CA2466880A1 (en) 2001-11-09 2003-05-15 Artecel Sciences, Inc. Methods and compositions for the use of stromal cells to support embryonic and adult stem cells
KR101083454B1 (ko) * 2001-12-07 2011-11-16 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한 시스템 및 방법
JP2007508018A (ja) * 2003-10-08 2007-04-05 べト−ステム インコーポレイテッド 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット
US8715733B2 (en) * 2004-07-23 2014-05-06 DePuy Synthes Products, LLC Enhanced adipose tissue
US20100092432A1 (en) 2006-08-08 2010-04-15 Takenori Ozaki Cell preparation containing multipotential stem cells originating in fat tissue
US8835170B2 (en) * 2006-10-06 2014-09-16 University Of Virginia Patent Foundation Methods and compositions useful for diabetic wound healing
AU2009227022B2 (en) 2008-03-19 2014-07-03 Cryo-Save Ag Improved cryopreservation of adipose tissue for the isolation of mesenchymal stem cells
WO2009152084A2 (en) 2008-06-11 2009-12-17 Cell4Vet Llc Adipose tissue-derived stem cells for veterinary use
AU2009201915C1 (en) 2008-08-22 2015-02-26 Regeneus Ltd Therapeutic methods
ES2479621T3 (es) * 2009-04-28 2014-07-24 Anterogen Co., Ltd. Composición de células madre estromales derivadas de tejido adiposo autólogo y alogénico destinada al tratamiento de fístulas
US20120201791A1 (en) * 2009-10-15 2012-08-09 Tai June Yoo Methods of treating diseases or conditions using mesenchymal stem cells
CN103596577B (zh) * 2011-03-15 2017-02-15 赛尔爱迪尔私人有限公司 包含脂肪组织来源的分泌物的组合物在制备用于局部治疗或预防个体中痤疮的药物中的用途
DK3546569T3 (da) * 2011-09-23 2021-07-12 Cell Ideas Pty Ltd Terapeutiske midler med anvendelse af fedtceller og cellesekreter

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021155461A (ja) * 2011-09-23 2021-10-07 レジニアス リミテッド 脂肪細胞および細胞分泌物を使用する治療
JP7022863B2 (ja) 2011-09-23 2022-02-18 レジニアス リミテッド 脂肪細胞および細胞分泌物を使用する治療
JP2022033865A (ja) * 2011-09-23 2022-03-02 レジニアス リミテッド 脂肪細胞および細胞分泌物を使用する治療

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SG2014013676A (en) 2014-05-29
SG10201606745XA (en) 2016-10-28
EP3546569A1 (en) 2019-10-02
DK3546569T3 (da) 2021-07-12
CA2885487C (en) 2021-11-16
ES2880084T3 (es) 2021-11-23
JP2014527821A (ja) 2014-10-23
US10660921B2 (en) 2020-05-26
JP2022033865A (ja) 2022-03-02
EP2744892A1 (en) 2014-06-25
DK2744892T3 (en) 2019-04-23
JP7022863B2 (ja) 2022-02-18
JP6912512B2 (ja) 2021-08-04
JP6839038B2 (ja) 2021-03-03
WO2013040649A1 (en) 2013-03-28
EP2744892B1 (en) 2019-03-20
AU2012313352A1 (en) 2013-05-02
AU2012313352B2 (en) 2015-07-02
EP3546569B1 (en) 2021-06-16
AU2012313352A9 (en) 2013-09-26
CA2885487A1 (en) 2013-03-28
EP3868871A1 (en) 2021-08-25
US20190015455A1 (en) 2019-01-17
US10111909B2 (en) 2018-10-30
US20140234272A1 (en) 2014-08-21
EP2744892A4 (en) 2015-05-20
JP2021155461A (ja) 2021-10-07
JP2019142971A (ja) 2019-08-29
JP2017193566A (ja) 2017-10-26
ES2721180T3 (es) 2019-07-29
US20200261510A1 (en) 2020-08-20

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