SG170620A1 - Novel compounds, pharmaceutical compositions containing same, and methods of use for same - Google Patents
Novel compounds, pharmaceutical compositions containing same, and methods of use for sameInfo
- Publication number
- SG170620A1 SG170620A1 SG200806631-8A SG2008066318A SG170620A1 SG 170620 A1 SG170620 A1 SG 170620A1 SG 2008066318 A SG2008066318 A SG 2008066318A SG 170620 A1 SG170620 A1 SG 170620A1
- Authority
- SG
- Singapore
- Prior art keywords
- group
- cycloalkyl
- alkenyl
- alkyl
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39280902P | 2002-07-01 | 2002-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG170620A1 true SG170620A1 (en) | 2011-05-30 |
Family
ID=30115535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200806631-8A SG170620A1 (en) | 2002-07-01 | 2003-07-01 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060241177A1 (fr) |
| EP (1) | EP1534263A4 (fr) |
| JP (1) | JP2005533107A (fr) |
| KR (1) | KR20050072670A (fr) |
| CN (2) | CN100482219C (fr) |
| AU (1) | AU2003248810B2 (fr) |
| BR (1) | BRPI0312413A2 (fr) |
| CA (1) | CA2491183A1 (fr) |
| EA (1) | EA010484B1 (fr) |
| HK (1) | HK1086485A1 (fr) |
| IL (1) | IL166054A0 (fr) |
| MX (1) | MXPA05000152A (fr) |
| SG (1) | SG170620A1 (fr) |
| WO (1) | WO2004006835A2 (fr) |
| ZA (1) | ZA200500203B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9018737D0 (en) * | 1990-08-28 | 1990-10-10 | Goodfellow John W | Phosphetic patellar components |
| AU2003215111A1 (en) | 2002-02-08 | 2003-09-02 | The Johns Hopkins University School Of Medicine | Stimulation of cpt-1 as a means to reduce weight |
| CN101721412A (zh) * | 2002-07-09 | 2010-06-09 | 法斯根有限责任公司 | 治疗人和动物中微生物感染的方法 |
| CN101007796A (zh) * | 2006-01-27 | 2007-08-01 | 北京摩力克科技有限公司 | 新型五元杂环化合物及其制备方法和医疗用途 |
| CN101190904A (zh) * | 2006-11-23 | 2008-06-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 脂肪酸合成酶抑制剂及其制药用途 |
| AU2008287542C1 (en) | 2007-06-01 | 2015-01-22 | The Trustees Of Princeton University | Treatment of viral infections by modulation of host cell metabolic pathways |
| WO2010118324A2 (fr) | 2009-04-09 | 2010-10-14 | Nuclea Biotechnologies, LLC | Anticorps dirigés contre la synthase des acides gras |
| FR2957078B1 (fr) * | 2010-03-05 | 2012-05-04 | Centre Nat Rech Scient | Acides paraconiques comme activateurs de pigmentation |
| WO2011140296A1 (fr) | 2010-05-05 | 2011-11-10 | Infinity Pharmaceuticals | Triazoles utilisés comme inhibiteurs d'acides gras synthase (fasn) |
| EP3159331A1 (fr) | 2010-05-05 | 2017-04-26 | Infinity Pharmaceuticals, Inc. | Tretrazolones utilisées comme inhibiteurs de synthase d'acide gras |
| JP6285442B2 (ja) * | 2012-09-07 | 2018-02-28 | ヤンセン ファーマシューティカ エヌ．ベー． | がん治療用の脂肪酸合成酵素（ｆａｓｎ）阻害剤として有用なイミダゾリン−５−オン誘導体 |
| CN103145662B (zh) * | 2013-02-18 | 2014-07-16 | 深圳万和制药有限公司 | N-取代的氨基丁内酯衍生物及其用途 |
| CN103864731B (zh) * | 2014-02-19 | 2016-01-20 | 成都中医药大学 | 含季碳手性中心的呋喃内酯环类化合物的合成方法 |
| CN104530018B (zh) * | 2014-12-12 | 2017-04-12 | 郑州大学 | 含α‑亚甲基‑γ‑丁内酯结构的吲哚类化合物、制备方法及其应用 |
| CN107406400B (zh) * | 2015-02-05 | 2020-08-04 | 德米拉公司 | 用于制备(5-十四烷氧基)呋喃-2-甲酸2-((2-乙氧基-2-氧代乙基)(甲基)氨基)-2-氧代乙酯的合成方法 |
| KR102038971B1 (ko) * | 2018-03-12 | 2019-11-26 | 주식회사 엔지켐생명과학 | 디아실글리세롤락톤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역증진제 |
| KR20220159831A (ko) | 2021-05-26 | 2022-12-05 | 울산과학기술원 | 미토콘드리아 표적화 뉴클레오펩티드 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496187A (en) * | 1967-03-20 | 1970-02-17 | American Home Prod | N-(heterocyclyl)aconamides |
| US3472878A (en) * | 1969-01-27 | 1969-10-14 | American Home Prod | N-(hydroxyaryl)aconamides |
| US4753871A (en) * | 1986-12-12 | 1988-06-28 | Eastman Kodak Company | Cyan dye-forming couplers and photographic materials containing same |
| JPS63169848A (ja) * | 1987-01-07 | 1988-07-13 | Nec Corp | デジタルデ−タ通信におけるデ−タ端末収容方式 |
| JP2524760B2 (ja) * | 1987-07-10 | 1996-08-14 | テイカ株式会社 | 新規抗生物質 |
| JPH04199148A (ja) * | 1990-11-29 | 1992-07-20 | Konica Corp | ハロゲン化銀写真感光材料 |
| JPH05246822A (ja) * | 1992-03-07 | 1993-09-24 | Nippon Paint Co Ltd | 抗菌剤 |
| JPH07112931A (ja) * | 1993-08-27 | 1995-05-02 | Nippon Paint Co Ltd | エプスタイン−バーウイルス活性化抑制剤 |
| DK0869784T3 (da) * | 1995-11-17 | 2006-01-16 | Univ Johns Hopkins | Hæmning af fedtsyresyntase som middel til formindskelse af adipocytmængden |
| DE60028996T2 (de) * | 1999-11-12 | 2007-02-08 | The Johns Hopkins University School Of Medicine | Behandlung von krebs durch erhöhung des malonyl-coa-spiegels |
| JP2003528051A (ja) * | 2000-02-16 | 2003-09-24 | ザ ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン | ニューロペプチドｙレベルの減少によって誘導される体重減少 |
-
2003
- 2003-07-01 BR BRPI0312413A patent/BRPI0312413A2/pt not_active IP Right Cessation
- 2003-07-01 CA CA002491183A patent/CA2491183A1/fr not_active Abandoned
- 2003-07-01 EP EP03764343A patent/EP1534263A4/fr not_active Withdrawn
- 2003-07-01 AU AU2003248810A patent/AU2003248810B2/en not_active Ceased
- 2003-07-01 US US10/519,804 patent/US20060241177A1/en not_active Abandoned
- 2003-07-01 IL IL16605403A patent/IL166054A0/xx unknown
- 2003-07-01 CN CNB038183692A patent/CN100482219C/zh not_active Expired - Fee Related
- 2003-07-01 CN CN200910126506A patent/CN101633650A/zh active Pending
- 2003-07-01 WO PCT/US2003/020960 patent/WO2004006835A2/fr active Application Filing
- 2003-07-01 JP JP2004521521A patent/JP2005533107A/ja active Pending
- 2003-07-01 ZA ZA200500203A patent/ZA200500203B/xx unknown
- 2003-07-01 EA EA200500122A patent/EA010484B1/ru not_active IP Right Cessation
- 2003-07-01 KR KR1020047021601A patent/KR20050072670A/ko not_active Application Discontinuation
- 2003-07-01 SG SG200806631-8A patent/SG170620A1/en unknown
- 2003-07-01 MX MXPA05000152A patent/MXPA05000152A/es not_active Application Discontinuation
-
2006
- 2006-06-07 HK HK06106502.2A patent/HK1086485A1/xx not_active IP Right Cessation
Non-Patent Citations (2)
| Title |
|---|
| SYNTHESIS AND ABSOLUTE STEREOCHEMISTRY OF (-)- PROTOLICHESTERINIC ACID, ANTITUMOR ANTIBIOTIC LACTONE FROM CETRARIA ISLANDICA * |
| SYNTHESIS AND ANTITUMOR ACTIVITY OF AN INHIBITOR OF FATTY ACID SYNTHASE * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL166054A0 (en) | 2006-01-15 |
| EA010484B1 (ru) | 2008-10-30 |
| ZA200500203B (en) | 2009-09-30 |
| HK1086485A1 (en) | 2006-09-22 |
| MXPA05000152A (es) | 2005-10-24 |
| KR20050072670A (ko) | 2005-07-12 |
| CN101633650A (zh) | 2010-01-27 |
| EP1534263A4 (fr) | 2006-10-11 |
| EA200500122A1 (ru) | 2005-12-29 |
| JP2005533107A (ja) | 2005-11-04 |
| EP1534263A2 (fr) | 2005-06-01 |
| WO2004006835A3 (fr) | 2004-07-22 |
| BRPI0312413A2 (pt) | 2016-08-02 |
| CN1705478A (zh) | 2005-12-07 |
| AU2003248810A1 (en) | 2004-02-02 |
| US20060241177A1 (en) | 2006-10-26 |
| CN100482219C (zh) | 2009-04-29 |
| AU2003248810B2 (en) | 2009-08-20 |
| WO2004006835A2 (fr) | 2004-01-22 |
| CA2491183A1 (fr) | 2004-01-22 |
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