UA97104C2 - Полиненасыщеные соединения, способ их получения и композиции, которые их содержат - Google Patents
Полиненасыщеные соединения, способ их получения и композиции, которые их содержатInfo
- Publication number
- UA97104C2 UA97104C2 UAA200809182A UAA200809182A UA97104C2 UA 97104 C2 UA97104 C2 UA 97104C2 UA A200809182 A UAA200809182 A UA A200809182A UA A200809182 A UAA200809182 A UA A200809182A UA 97104 C2 UA97104 C2 UA 97104C2
- Authority
- UA
- Ukraine
- Prior art keywords
- optionally substituted
- group
- branched
- linear
- residue
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 abstract 2
- -1 hydroxy, acetoxy Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000007854 depigmenting agent Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000005549 heteroarylene group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 125000005649 substituted arylene group Chemical group 0.000 abstract 1
- 230000002087 whitening effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Изобретение касается новых полиненасыщеных соединений формулы (I): EMBED ISISServer , (I) где R1 является группой R'1 или -A-R'1, в которой R'1 выбран из -СООН, -COOR3, -CONH2, -CONHR3, -CONR3R4, -СНО, -СН2ВОН, -CH2OR5, и А есть С1-С16-алкиленовой группой, С2-С16-алкениленовой группой или С2-С16-алкиниленовой группой; R2 является необязательно замещенной арильной или гетероарильной группой, азидным остатком или остатком жирной кислоты, необязательно разветвленным и/или замещенным, лучше, в конце цепи и, в частности, гидрокси, ацетокси или защищенным или незащищенным аминорадикалом, группой -ОС-(СН2) n-со-токоферил (альфа-, бета- или гамма-, или дельта-) с 2≤n≤10, группой –R'2-O-R6, где R'2 является необязательно замещенной ариленовою группой или необязательно замещенной гетероариленовой группой, и R6 является атомом водорода, необязательно замещенными линейными или разветвленными С1-С16-алкильными группами, необязательно замещенной линейной или разветвленной С2-С16-алкенильной группой или необязательно замещенной линейной или разветвленной С2-С16-алкинильной группой, необязательно замещенным токоферильным радикалом и т.п., аминокислотным остатком или азидным остатком. Также изобретение касается композиций, в частности косметических или дерматологических композиций, которые содержат соединения формулы (I), и их применения в качестве отбеливающего или осветляющего агента и косметического способа применения этих композиций.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0512661A FR2894577B1 (fr) | 2005-12-14 | 2005-12-14 | Nouveaux composes polyinsatures, leur procede de preparation et les compositions les contenant. |
PCT/EP2006/069731 WO2007068745A1 (fr) | 2005-12-14 | 2006-12-14 | Nouveaux composés polyinsaturés, leur procédé de préparation et les compositions les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
UA97104C2 true UA97104C2 (ru) | 2012-01-10 |
Family
ID=36649328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200809182A UA97104C2 (ru) | 2005-12-14 | 2006-12-14 | Полиненасыщеные соединения, способ их получения и композиции, которые их содержат |
Country Status (19)
Country | Link |
---|---|
US (1) | US8420610B2 (ru) |
EP (1) | EP1968993B1 (ru) |
JP (1) | JP5306819B2 (ru) |
KR (1) | KR20080077003A (ru) |
CN (1) | CN101356182A (ru) |
AT (1) | ATE540964T1 (ru) |
AU (1) | AU2006325223C1 (ru) |
BR (1) | BRPI0619959A2 (ru) |
CA (1) | CA2633225C (ru) |
FR (1) | FR2894577B1 (ru) |
IL (1) | IL192065A (ru) |
MA (1) | MA30160B1 (ru) |
MX (1) | MX2008007792A (ru) |
NZ (1) | NZ569321A (ru) |
RU (1) | RU2466988C2 (ru) |
TN (1) | TNSN08261A1 (ru) |
UA (1) | UA97104C2 (ru) |
WO (1) | WO2007068745A1 (ru) |
ZA (1) | ZA200805740B (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2894465B1 (fr) * | 2005-12-14 | 2010-09-10 | Fabre Pierre Dermo Cosmetique | Utilisation de composes polyinsatures en tant qu'agents blanchissants |
US20100204498A1 (en) * | 2007-09-19 | 2010-08-12 | Munekazu Iinuma | Agent having neurotrophic factor-like activity |
CN101591280B (zh) * | 2008-05-30 | 2012-08-22 | 安徽医科大学 | 具有肿瘤诱导分化作用的类维甲酸衍生物及其药物组合物与用途 |
FR2945442B1 (fr) * | 2009-05-14 | 2012-08-03 | Fabre Pierre Dermo Cosmetique | Utilisation de delta-tocopheryl-glucide en tant qu'agent depigmentant. |
AU2012249921B2 (en) * | 2011-04-26 | 2017-06-08 | Biojiva Llc | Oxidative retinal diseases |
WO2016168535A1 (en) * | 2015-04-15 | 2016-10-20 | Valent Biosciences Corporation | (s)-2'-vinyl-abscisic acid derivatives |
CN114029072B (zh) * | 2021-12-01 | 2023-07-11 | 万华化学集团股份有限公司 | 一种固体超强酸催化剂及用其制备对甲氧基肉桂酸异辛酯的方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3068257A (en) | 1962-12-11 | Cxchs | ||
US3311656A (en) * | 1964-05-12 | 1967-03-28 | Hoffmann La Roche | Intermediates for the preparation of a carotenoid |
US5786391A (en) | 1995-01-11 | 1998-07-28 | Cornell Research Foundation, Inc. | Regulating gene expression using retinoids with Ch2 OH or related groups at the side chain terminal position |
FR2791679B1 (fr) * | 1999-03-31 | 2003-04-11 | Fabre Pierre Dermo Cosmetique | Bioprecurseurs aptes a liberer un derive retinoique par mise a profit de l'activite enzymatique de la surface cutanee et compositions pharmaceutiques et/ou cosmetiques |
EP1305274A4 (en) | 2000-07-11 | 2005-10-12 | Univ Maryland | NEW RETINOIDS SUBSTITUTED IN C-4 |
DE60219053T2 (de) * | 2001-10-31 | 2007-12-13 | Dsm Ip Assets B.V. | Herstellung von retinoiden |
FR2894465B1 (fr) * | 2005-12-14 | 2010-09-10 | Fabre Pierre Dermo Cosmetique | Utilisation de composes polyinsatures en tant qu'agents blanchissants |
-
2005
- 2005-12-14 FR FR0512661A patent/FR2894577B1/fr not_active Expired - Fee Related
-
2006
- 2006-12-14 MX MX2008007792A patent/MX2008007792A/es active IP Right Grant
- 2006-12-14 AU AU2006325223A patent/AU2006325223C1/en not_active Ceased
- 2006-12-14 AT AT06841375T patent/ATE540964T1/de active
- 2006-12-14 JP JP2008545006A patent/JP5306819B2/ja not_active Expired - Fee Related
- 2006-12-14 EP EP06841375A patent/EP1968993B1/fr active Active
- 2006-12-14 UA UAA200809182A patent/UA97104C2/ru unknown
- 2006-12-14 RU RU2008128318/04A patent/RU2466988C2/ru not_active IP Right Cessation
- 2006-12-14 CA CA2633225A patent/CA2633225C/fr not_active Expired - Fee Related
- 2006-12-14 NZ NZ569321A patent/NZ569321A/en not_active IP Right Cessation
- 2006-12-14 KR KR1020087016703A patent/KR20080077003A/ko not_active Application Discontinuation
- 2006-12-14 US US12/086,625 patent/US8420610B2/en not_active Expired - Fee Related
- 2006-12-14 BR BRPI0619959-3A patent/BRPI0619959A2/pt not_active IP Right Cessation
- 2006-12-14 WO PCT/EP2006/069731 patent/WO2007068745A1/fr active Application Filing
- 2006-12-14 CN CNA2006800508101A patent/CN101356182A/zh active Pending
-
2008
- 2008-06-11 IL IL192065A patent/IL192065A/en not_active IP Right Cessation
- 2008-06-13 TN TNP2008000261A patent/TNSN08261A1/fr unknown
- 2008-07-01 ZA ZA200805740A patent/ZA200805740B/xx unknown
- 2008-07-11 MA MA31113A patent/MA30160B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
RU2008128318A (ru) | 2010-01-20 |
US20100168045A1 (en) | 2010-07-01 |
WO2007068745A1 (fr) | 2007-06-21 |
ATE540964T1 (de) | 2012-01-15 |
JP2009519298A (ja) | 2009-05-14 |
BRPI0619959A2 (pt) | 2011-10-25 |
IL192065A (en) | 2013-09-30 |
FR2894577A1 (fr) | 2007-06-15 |
RU2466988C2 (ru) | 2012-11-20 |
CA2633225A1 (fr) | 2007-06-21 |
AU2006325223B2 (en) | 2012-07-19 |
EP1968993A1 (fr) | 2008-09-17 |
EP1968993B1 (fr) | 2012-01-11 |
NZ569321A (en) | 2010-04-30 |
KR20080077003A (ko) | 2008-08-20 |
US8420610B2 (en) | 2013-04-16 |
CA2633225C (fr) | 2014-11-18 |
TNSN08261A1 (fr) | 2009-10-30 |
IL192065A0 (en) | 2008-12-29 |
FR2894577B1 (fr) | 2008-02-22 |
MX2008007792A (es) | 2008-09-15 |
AU2006325223A1 (en) | 2007-06-21 |
JP5306819B2 (ja) | 2013-10-02 |
CN101356182A (zh) | 2009-01-28 |
MA30160B1 (fr) | 2009-01-02 |
AU2006325223C1 (en) | 2013-03-14 |
ZA200805740B (en) | 2009-08-26 |
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