TW200508208A - Novel compound of 6-methyl-3-phenethyl-3,4-dihydro-1H-quinazoline-2-thione, its preparation and a depigmentation composition containing the same as an effective component - Google Patents
Novel compound of 6-methyl-3-phenethyl-3,4-dihydro-1H-quinazoline-2-thione, its preparation and a depigmentation composition containing the same as an effective componentInfo
- Publication number
- TW200508208A TW200508208A TW092133158A TW92133158A TW200508208A TW 200508208 A TW200508208 A TW 200508208A TW 092133158 A TW092133158 A TW 092133158A TW 92133158 A TW92133158 A TW 92133158A TW 200508208 A TW200508208 A TW 200508208A
- Authority
- TW
- Taiwan
- Prior art keywords
- same
- effective component
- quinazoline
- phenethyl
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/93—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a novel compound of 6-methyl-3-phenethyl-3,4-dihydro-1H-quinazoline-2-thione represented by the following formula 1, a preparation method thereof, a medicinal composition for prevention and treatment of hyperpigmentation comprising the same as an effective component, and a skin-whitening cosmetic composition comprising the same as an effective component,
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020030057135A KR100747042B1 (en) | 2003-08-19 | 2003-08-19 | Novel compound of 6-methyl-3-phenethyl-3,4-dihydro-1H-quinazoline-2-thione, its preparation and a depigmentation composition containing the compound as an effective component |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200508208A true TW200508208A (en) | 2005-03-01 |
TWI308148B TWI308148B (en) | 2009-04-01 |
Family
ID=34192126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW092133158A TWI308148B (en) | 2003-08-19 | 2003-11-26 | Novel compound of 6-methyl-3-phenethyl-3,4-dihydro-1h-quinazoline-2-thione, its preparation and a depigmentation composition containing the same as an effective component |
Country Status (4)
Country | Link |
---|---|
KR (1) | KR100747042B1 (en) |
AU (1) | AU2003282429A1 (en) |
TW (1) | TWI308148B (en) |
WO (1) | WO2005016895A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107920652A (en) * | 2015-08-24 | 2018-04-17 | 阿莫生命科学有限公司 | Beauty mask and preparation method thereof |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101104307B1 (en) * | 2009-07-10 | 2012-01-11 | 충북대학교 산학협력단 | Novel dihydroquinazoline-2-thione derivatives and composition containing these compounds as an effective component for depigmentation |
US8293218B2 (en) * | 2010-07-29 | 2012-10-23 | Conopco, Inc. | Skin care compositions comprising substituted monoamines |
US8476251B2 (en) | 2010-07-29 | 2013-07-02 | Conopco, Inc. | Skin care compositions comprising substituted diamines |
US20130273183A1 (en) * | 2012-04-13 | 2013-10-17 | Eastman Chemical Company | 2-Pyrimidine Thioesters and Thiocarbonates as Skin Brightening Agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3077046B2 (en) * | 1992-08-31 | 2000-08-14 | 久光製薬株式会社 | New quinazoline derivatives |
US6750229B2 (en) * | 1998-07-06 | 2004-06-15 | Johnson & Johnson Consumer Companies, Inc. | Methods for treating skin pigmentation |
JP4249855B2 (en) * | 1999-08-31 | 2009-04-08 | 実 土屋 | Moving bed type filtration equipment using floating media |
DE10008907A1 (en) * | 2000-02-25 | 2001-08-30 | Haarmann & Reimer Gmbh | Topical cosmetic compositions containing benzocondensed or heterocyclically condensed 2-hydrazino-1,3-heteroazoles |
GB0124627D0 (en) * | 2001-10-15 | 2001-12-05 | Smithkline Beecham Plc | Novel compounds |
-
2003
- 2003-08-19 KR KR1020030057135A patent/KR100747042B1/en not_active IP Right Cessation
- 2003-11-25 AU AU2003282429A patent/AU2003282429A1/en not_active Abandoned
- 2003-11-25 WO PCT/KR2003/002545 patent/WO2005016895A1/en active Application Filing
- 2003-11-26 TW TW092133158A patent/TWI308148B/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107920652A (en) * | 2015-08-24 | 2018-04-17 | 阿莫生命科学有限公司 | Beauty mask and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
AU2003282429A1 (en) | 2005-03-07 |
KR20050019401A (en) | 2005-03-03 |
KR100747042B1 (en) | 2007-08-07 |
TWI308148B (en) | 2009-04-01 |
WO2005016895A1 (en) | 2005-02-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |