SG139556A1 - Method for inhibiting bone resorption - Google Patents

Method for inhibiting bone resorption

Info

Publication number
SG139556A1
SG139556A1 SG200603406-0A SG2006034060A SG139556A1 SG 139556 A1 SG139556 A1 SG 139556A1 SG 2006034060 A SG2006034060 A SG 2006034060A SG 139556 A1 SG139556 A1 SG 139556A1
Authority
SG
Singapore
Prior art keywords
bone resorption
inhibiting bone
disclosed
group
methods
Prior art date
Application number
SG200603406-0A
Other languages
English (en)
Inventor
Anastasia G Daifotis
Santora Arthur C Ii
Yates A John
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27451690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG139556(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9717590.5A external-priority patent/GB9717590D0/en
Priority claimed from GBGB9717850.3A external-priority patent/GB9717850D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SG139556A1 publication Critical patent/SG139556A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Fittings On The Vehicle Exterior For Carrying Loads, And Devices For Holding Or Mounting Articles (AREA)
  • Pit Excavations, Shoring, Fill Or Stabilisation Of Slopes (AREA)
  • Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
SG200603406-0A 1997-07-22 1998-07-17 Method for inhibiting bone resorption SG139556A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5335197P 1997-07-22 1997-07-22
US5353597P 1997-07-23 1997-07-23
GBGB9717590.5A GB9717590D0 (en) 1997-08-20 1997-08-20 Oral method for treating or preventing abnormal bone resorption
GBGB9717850.3A GB9717850D0 (en) 1997-08-22 1997-08-22 Oral method for treating or preventing abnormal bone resorption

Publications (1)

Publication Number Publication Date
SG139556A1 true SG139556A1 (en) 2008-02-29

Family

ID=27451690

Family Applications (2)

Application Number Title Priority Date Filing Date
SG200107221A SG109478A1 (en) 1997-07-22 1998-07-17 Method for inhibiting bone resorption
SG200603406-0A SG139556A1 (en) 1997-07-22 1998-07-17 Method for inhibiting bone resorption

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG200107221A SG109478A1 (en) 1997-07-22 1998-07-17 Method for inhibiting bone resorption

Country Status (31)

Country Link
EP (5) EP1151752A3 (el)
JP (2) JP3479780B2 (el)
KR (3) KR20030097610A (el)
CN (3) CN1602879A (el)
AT (2) ATE357921T1 (el)
AU (1) AU8493698A (el)
BG (1) BG66282B1 (el)
BR (1) BR9810779A (el)
CA (1) CA2294595C (el)
CY (2) CY1107535T1 (el)
DE (6) DE69803291T2 (el)
DK (2) DK0998292T3 (el)
EA (1) EA004544B2 (el)
EE (1) EE05603B1 (el)
ES (3) ES2269014T3 (el)
HK (5) HK1024166A1 (el)
ID (1) ID24096A (el)
IL (1) IL133535A0 (el)
IS (3) IS5315A (el)
LU (2) LU91222I2 (el)
NL (2) NL300223I1 (el)
NO (1) NO20000323L (el)
NZ (1) NZ501807A (el)
PL (1) PL195272B1 (el)
PT (2) PT1175904E (el)
SG (2) SG109478A1 (el)
SI (1) SI0998292T1 (el)
SK (1) SK932000A3 (el)
TR (1) TR200000145T2 (el)
UY (1) UY25950A1 (el)
WO (1) WO1999004773A2 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2220133T3 (es) * 1998-12-25 2004-12-01 Yamanouchi Pharmaceutical Co. Ltd. Composiciones de medicamentos que sirven para tratar las lesiones oseas en el mieloma multiple.
DE60019580T2 (de) * 1999-05-21 2006-03-09 Novartis Ag Verwendung von biphosphonsäuren zur behandlung von angiogenese
CA2344313C (en) * 1999-07-19 2007-11-27 Toray Industries, Inc. Agents for periodontal disease
AU2580001A (en) 1999-12-20 2001-07-03 Merck & Co., Inc. Blister package for pharmaceutical treatment card
AU2270101A (en) * 1999-12-20 2001-07-03 Merck & Co., Inc. Pharmaceutical kit
JP2004517800A (ja) * 2000-04-07 2004-06-17 ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム 両性イオンリン脂質およびビスホスホネートを含む独特の組成物および胃腸毒性を低減化したビスホスフェートデリバリーシステムとしての該組成物の使用
NZ523086A (en) 2000-06-20 2007-07-27 Novartis Ag Method of administering bisphosphonates
US6638920B2 (en) * 2000-07-21 2003-10-28 Merck & Co., Inc. Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
ATE330616T1 (de) * 2001-05-02 2006-07-15 Novartis Pharma Gmbh Verabreichung von bisphosphonaten durch inhalation zur behandlung von knochenresorption und osteoporosis
MXPA04009586A (es) 2002-05-10 2005-01-11 Hoffmann La Roche Acidos bisfosfonicos para el tratamiento y prevencion de la osteoporosis.
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
WO2005027921A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a bisphosphonate
WO2005072747A1 (ja) * 2004-02-02 2005-08-11 Ono Pharmaceutical Co., Ltd. 骨吸収抑制剤
EP1937362B1 (en) * 2005-09-16 2013-03-27 Selamine Ltd. Bisphosphonate formulation
EP2648702B1 (en) * 2010-12-06 2019-03-06 Effrx Pharmaceuticals SA Stable effervescent bisphosphonate formulations with rapid solubilization characteristics
CN106924257B (zh) * 2017-03-14 2019-11-19 湖南赛隆药业有限公司 质子泵抑制剂和抗骨质疏松药的复合物及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989004178A1 (en) * 1987-11-13 1989-05-18 Aktiebolaget Hässle New therapeutical use of h2-receptor-blocking compounds
US5364616A (en) * 1992-04-15 1994-11-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
US5393531A (en) * 1991-07-01 1995-02-28 Gerhard; Gergely Process for the preparation of a pharmaceutical formulation containing at least two different active substances and use of such a formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL84731A0 (en) * 1986-12-19 1988-05-31 Norwich Eaton Pharma Heterocycle-substituted diphosphonic acids and salts and esters and pharmaceutical compositions containing them
HU227530B1 (en) * 1991-11-22 2011-07-28 Warner Chilcott Company Delayed-release compositions containing risedronate and process for their production
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
CA2138367C (en) * 1992-06-30 1998-09-22 Marion David Francis Use of phosphonates for the treatment of osteoporosis
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
CA2221416A1 (en) * 1995-06-06 1996-12-12 Merck & Co., Inc. Bisphosphonate therapy for bone loss associated with rheumatoid arthritis
WO1997044017A1 (en) * 1996-05-17 1997-11-27 Merck & Co., Inc. Effervescent bisphosphonate formulation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989004178A1 (en) * 1987-11-13 1989-05-18 Aktiebolaget Hässle New therapeutical use of h2-receptor-blocking compounds
US5393531A (en) * 1991-07-01 1995-02-28 Gerhard; Gergely Process for the preparation of a pharmaceutical formulation containing at least two different active substances and use of such a formulation
US5364616A (en) * 1992-04-15 1994-11-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis

Also Published As

Publication number Publication date
HK1040495A1 (zh) 2002-06-14
EA004544B2 (ru) 2006-12-29
KR20030097611A (ko) 2003-12-31
WO1999004773A3 (en) 1999-04-15
NO20000323D0 (no) 2000-01-21
CN1265035A (zh) 2000-08-30
EP1132088A3 (en) 2002-04-24
IS7231A (is) 2004-04-21
CN1299689C (zh) 2007-02-14
BG104093A (en) 2000-10-31
UY25950A1 (es) 2000-09-29
BG66282B1 (bg) 2013-01-31
DE69837450D1 (de) 2007-05-10
IL133535A0 (en) 2001-04-30
IS5315A (is) 1999-12-21
DE01201911T1 (de) 2007-10-18
ATE357921T1 (de) 2007-04-15
DE01201913T1 (de) 2007-02-08
IS7230A (is) 2004-04-21
EP1175904B1 (en) 2007-03-28
LU91364I2 (fr) 2007-11-12
EP1175904B8 (en) 2007-05-09
EP1175903A2 (en) 2002-01-30
ES2269014T3 (es) 2007-05-01
NO20000323L (no) 2000-03-20
CA2294595C (en) 2001-08-21
JP3479780B2 (ja) 2003-12-15
BR9810779A (pt) 2000-07-25
EA004544B1 (ru) 2004-06-24
EP0998292A2 (en) 2000-05-10
WO1999004773A2 (en) 1999-02-04
SI0998292T1 (en) 2002-04-30
PL195272B1 (pl) 2007-08-31
PT1175904E (pt) 2007-04-30
HK1042232A1 (zh) 2002-08-09
CY1107535T1 (el) 2012-01-25
HK1042230A1 (zh) 2002-08-09
EP1132088A2 (en) 2001-09-12
ES2269014T1 (es) 2007-04-01
ATE209037T1 (de) 2001-12-15
DE69803291T2 (de) 2002-08-08
SG109478A1 (en) 2005-03-30
EA200000151A1 (ru) 2000-10-30
LU91222I2 (fr) 2006-04-18
CN1166365C (zh) 2004-09-15
CY2007022I2 (el) 2012-01-25
CA2294595A1 (en) 1999-02-04
CN1602879A (zh) 2005-04-06
NL300292I1 (nl) 2007-11-01
ES2253136T1 (es) 2006-06-01
ID24096A (id) 2000-07-06
KR100391732B1 (ko) 2003-07-16
NZ501807A (en) 2003-02-28
CY2007022I1 (el) 2012-01-25
ES2164447T3 (es) 2002-02-16
JP2002502433A (ja) 2002-01-22
EP1175904A3 (en) 2002-12-18
EP1151752A2 (en) 2001-11-07
DK0998292T3 (da) 2002-05-13
EE05603B1 (et) 2012-12-17
PT998292E (pt) 2002-04-29
WO1999004773A9 (en) 1999-10-28
CN1602880A (zh) 2005-04-06
EE200000040A (et) 2000-10-16
KR20030097610A (ko) 2003-12-31
HK1024166A1 (en) 2000-10-05
PL338635A1 (en) 2000-11-06
EP1175903A3 (en) 2002-12-18
KR20010022110A (ko) 2001-03-15
AU8493698A (en) 1999-02-16
EP0998292B1 (en) 2001-11-21
EP1175904A2 (en) 2002-01-30
HK1040494A1 (zh) 2002-06-14
DE69837450T2 (de) 2007-08-23
DE122006000009I1 (de) 2006-06-14
NL300223I1 (nl) 2006-04-03
SK932000A3 (en) 2000-09-12
DK1175904T3 (da) 2007-05-07
DE122007000063I1 (de) 2007-12-20
DE69803291D1 (de) 2002-02-21
EP1151752A3 (en) 2002-12-18
JP2005068010A (ja) 2005-03-17
TR200000145T2 (tr) 2000-05-22

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