CY2007022I2 - Μεθοδος παρεμποδισης της απορροφησης οστων - Google Patents

Μεθοδος παρεμποδισης της απορροφησης οστων

Info

Publication number
CY2007022I2
CY2007022I2 CY2007022C CY2007022C CY2007022I2 CY 2007022 I2 CY2007022 I2 CY 2007022I2 CY 2007022 C CY2007022 C CY 2007022C CY 2007022 C CY2007022 C CY 2007022C CY 2007022 I2 CY2007022 I2 CY 2007022I2
Authority
CY
Cyprus
Prior art keywords
bone resorption
preventing bone
preventing
resorption
bone
Prior art date
Application number
CY2007022C
Other languages
English (en)
Other versions
CY2007022I1 (el
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27451690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2007022(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9717590.5A external-priority patent/GB9717590D0/en
Priority claimed from GBGB9717850.3A external-priority patent/GB9717850D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of CY2007022I1 publication Critical patent/CY2007022I1/el
Publication of CY2007022I2 publication Critical patent/CY2007022I2/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pit Excavations, Shoring, Fill Or Stabilisation Of Slopes (AREA)
  • Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
  • Fittings On The Vehicle Exterior For Carrying Loads, And Devices For Holding Or Mounting Articles (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CY2007022C 1997-07-22 2007-09-20 Μεθοδος παρεμποδισης της απορροφησης οστων CY2007022I2 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5335197P 1997-07-22 1997-07-22
US5353597P 1997-07-23 1997-07-23
GBGB9717590.5A GB9717590D0 (en) 1997-08-20 1997-08-20 Oral method for treating or preventing abnormal bone resorption
GBGB9717850.3A GB9717850D0 (en) 1997-08-22 1997-08-22 Oral method for treating or preventing abnormal bone resorption
PCT/US1998/014796 WO1999004773A2 (en) 1997-07-22 1998-07-17 Method for inhibiting bone resorption

Publications (2)

Publication Number Publication Date
CY2007022I1 CY2007022I1 (el) 2012-01-25
CY2007022I2 true CY2007022I2 (el) 2012-01-25

Family

ID=27451690

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20071100442T CY1107535T1 (el) 1997-07-22 2007-03-29 Μεθοδος παρεμποδισης της απορροφησης οστων
CY2007022C CY2007022I2 (el) 1997-07-22 2007-09-20 Μεθοδος παρεμποδισης της απορροφησης οστων

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20071100442T CY1107535T1 (el) 1997-07-22 2007-03-29 Μεθοδος παρεμποδισης της απορροφησης οστων

Country Status (31)

Country Link
EP (5) EP1175904B8 (el)
JP (2) JP3479780B2 (el)
KR (3) KR20030097610A (el)
CN (3) CN1602879A (el)
AT (2) ATE357921T1 (el)
AU (1) AU8493698A (el)
BG (1) BG66282B1 (el)
BR (1) BR9810779A (el)
CA (1) CA2294595C (el)
CY (2) CY1107535T1 (el)
DE (6) DE01201913T1 (el)
DK (2) DK0998292T3 (el)
EA (1) EA004544B2 (el)
EE (1) EE05603B1 (el)
ES (3) ES2269014T3 (el)
HK (5) HK1024166A1 (el)
ID (1) ID24096A (el)
IL (1) IL133535A0 (el)
IS (3) IS5315A (el)
LU (2) LU91222I2 (el)
NL (2) NL300223I1 (el)
NO (1) NO20000323L (el)
NZ (1) NZ501807A (el)
PL (1) PL195272B1 (el)
PT (2) PT998292E (el)
SG (2) SG139556A1 (el)
SI (1) SI0998292T1 (el)
SK (1) SK932000A3 (el)
TR (1) TR200000145T2 (el)
UY (1) UY25950A1 (el)
WO (1) WO1999004773A2 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000038694A1 (fr) 1998-12-25 2000-07-06 Yamanouchi Pharmaceutical Co., Ltd. Compositions de medicaments servant a traiter les lesions osseuses dans le myelome multiple
DK1178810T3 (da) * 1999-05-21 2005-07-11 Novartis Ag Anvendelse af bisphosphonsyrer til behandling af angiogenese
US6670343B1 (en) * 1999-07-19 2003-12-30 Toray Industries, Inc. Drugs for periodontal disease
WO2001045636A1 (en) * 1999-12-20 2001-06-28 Merck & Co., Inc. Pharmaceutical kit
WO2001046040A1 (en) 1999-12-20 2001-06-28 Merck & Co., Inc. Blister package for pharmaceutical treatment card
BR0110316A (pt) * 2000-04-07 2005-01-18 Regents For The University Of Composições únicas de fosfolipìdios e bisfosfonatos zwitteriÈnicos e uso das composições como sistemas de distribuição de bisfosfatos com toxicidade gi reduzida
AU7410901A (en) 2000-06-20 2002-01-02 Novartis Ag Method of administering bisphosphonates
US6638920B2 (en) * 2000-07-21 2003-10-28 Merck & Co., Inc. Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
CA2444718A1 (en) * 2001-05-02 2002-11-14 Novartis Ag Method of administration of bisphosphonates by inhalation in the treatment or prevention of bone resorption and osteoporosis
ES2294277T3 (es) * 2002-05-10 2008-04-01 F. Hoffmann-La Roche Ag Acidos bisfosfonicos para el tratamiento y prevencion de osteoporosis.
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
EP1667691A1 (en) * 2003-09-19 2006-06-14 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a bisphosphonate
WO2005072747A1 (ja) * 2004-02-02 2005-08-11 Ono Pharmaceutical Co., Ltd. 骨吸収抑制剤
JP2009508834A (ja) * 2005-09-16 2009-03-05 セラマイン リミテッド ビスホスホネート製剤
RU2608724C2 (ru) * 2010-12-06 2017-01-23 Эффэрикс Фармасьютикалз Са Стабильные составы шипучего бисфосфоната со свойствами быстрой солюбилизации
CN106924257B (zh) * 2017-03-14 2019-11-19 湖南赛隆药业有限公司 质子泵抑制剂和抗骨质疏松药的复合物及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL84731A0 (en) * 1986-12-19 1988-05-31 Norwich Eaton Pharma Heterocycle-substituted diphosphonic acids and salts and esters and pharmaceutical compositions containing them
SE8704436D0 (sv) * 1987-11-13 1987-11-13 Pm Konsult Handelsbolag Anvendning av antisekretoriska substanser for nya indikationer
DK0521388T3 (da) * 1991-07-01 1995-09-11 Gergely Gerhard Fremgangsmåde til fremstilling af et farmaceutisk præparat med mindst to forskellige aktivstoffer samt anvendelsen af et sådant præparat
HU227530B1 (en) * 1991-11-22 2011-07-28 Warner Chilcott Company Delayed-release compositions containing risedronate and process for their production
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
US5294433A (en) * 1992-04-15 1994-03-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
EP0648120B1 (en) * 1992-06-30 1997-12-29 PROCTER & GAMBLE PHARMACEUTICALS, INC. Use of phosphonates for the treatment of osteoporosis
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
JPH11506750A (ja) * 1995-06-06 1999-06-15 メルク エンド カンパニー インコーポレーテッド 慢性関節リウマチに係わる骨欠損に対するビスホスホネート療法
WO1997044017A1 (en) * 1996-05-17 1997-11-27 Merck & Co., Inc. Effervescent bisphosphonate formulation

Also Published As

Publication number Publication date
EP1175904A2 (en) 2002-01-30
NL300292I1 (nl) 2007-11-01
CN1602880A (zh) 2005-04-06
CY2007022I1 (el) 2012-01-25
AU8493698A (en) 1999-02-16
NO20000323L (no) 2000-03-20
EP1132088A3 (en) 2002-04-24
EA004544B1 (ru) 2004-06-24
NZ501807A (en) 2003-02-28
ATE357921T1 (de) 2007-04-15
CA2294595C (en) 2001-08-21
ES2164447T3 (es) 2002-02-16
IS7231A (is) 2004-04-21
EP1151752A2 (en) 2001-11-07
BR9810779A (pt) 2000-07-25
DE01201911T1 (de) 2007-10-18
CN1299689C (zh) 2007-02-14
EA004544B2 (ru) 2006-12-29
NO20000323D0 (no) 2000-01-21
SG139556A1 (en) 2008-02-29
JP2005068010A (ja) 2005-03-17
DE69803291T2 (de) 2002-08-08
IS7230A (is) 2004-04-21
DE122007000063I1 (de) 2007-12-20
PT998292E (pt) 2002-04-29
EP1151752A3 (en) 2002-12-18
HK1040494A1 (zh) 2002-06-14
JP3479780B2 (ja) 2003-12-15
EP0998292A2 (en) 2000-05-10
LU91222I2 (fr) 2006-04-18
KR20030097611A (ko) 2003-12-31
ES2269014T1 (es) 2007-04-01
PT1175904E (pt) 2007-04-30
CN1166365C (zh) 2004-09-15
HK1024166A1 (en) 2000-10-05
DE01201913T1 (de) 2007-02-08
EA200000151A1 (ru) 2000-10-30
IL133535A0 (en) 2001-04-30
LU91364I2 (fr) 2007-11-12
EP1175903A3 (en) 2002-12-18
EP1175904A3 (en) 2002-12-18
CA2294595A1 (en) 1999-02-04
EP0998292B1 (en) 2001-11-21
PL195272B1 (pl) 2007-08-31
HK1042230A1 (zh) 2002-08-09
EE05603B1 (et) 2012-12-17
KR20030097610A (ko) 2003-12-31
ES2253136T1 (es) 2006-06-01
ID24096A (id) 2000-07-06
CY1107535T1 (el) 2012-01-25
WO1999004773A9 (en) 1999-10-28
TR200000145T2 (tr) 2000-05-22
NL300223I1 (nl) 2006-04-03
KR20010022110A (ko) 2001-03-15
EP1175904B8 (en) 2007-05-09
DK1175904T3 (da) 2007-05-07
HK1042232A1 (zh) 2002-08-09
SI0998292T1 (en) 2002-04-30
DE69803291D1 (de) 2002-02-21
ES2269014T3 (es) 2007-05-01
HK1040495A1 (zh) 2002-06-14
EP1175904B1 (en) 2007-03-28
DK0998292T3 (da) 2002-05-13
UY25950A1 (es) 2000-09-29
ATE209037T1 (de) 2001-12-15
DE69837450T2 (de) 2007-08-23
JP2002502433A (ja) 2002-01-22
SG109478A1 (en) 2005-03-30
KR100391732B1 (ko) 2003-07-16
WO1999004773A3 (en) 1999-04-15
BG104093A (en) 2000-10-31
CN1602879A (zh) 2005-04-06
EE200000040A (et) 2000-10-16
WO1999004773A2 (en) 1999-02-04
BG66282B1 (bg) 2013-01-31
DE69837450D1 (de) 2007-05-10
CN1265035A (zh) 2000-08-30
EP1132088A2 (en) 2001-09-12
DE122006000009I1 (de) 2006-06-14
IS5315A (is) 1999-12-21
EP1175903A2 (en) 2002-01-30
PL338635A1 (en) 2000-11-06
SK932000A3 (en) 2000-09-12

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