SG11202111573VA - High performance fluorescence imaging module for genomic testing assay - Google Patents
High performance fluorescence imaging module for genomic testing assayInfo
- Publication number
- SG11202111573VA SG11202111573VA SG11202111573VA SG11202111573VA SG11202111573VA SG 11202111573V A SG11202111573V A SG 11202111573VA SG 11202111573V A SG11202111573V A SG 11202111573VA SG 11202111573V A SG11202111573V A SG 11202111573VA SG 11202111573V A SG11202111573V A SG 11202111573VA
- Authority
- SG
- Singapore
- Prior art keywords
- high performance
- imaging module
- fluorescence imaging
- genomic testing
- testing assay
- Prior art date
Links
- 238000003556 assay Methods 0.000 title 1
- 238000000799 fluorescence microscopy Methods 0.000 title 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N15/1436—Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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- G01N2015/1006—Investigating individual particles for cytology
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- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
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- Engineering & Computer Science (AREA)
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- Wood Science & Technology (AREA)
- Zoology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Multimedia (AREA)
- Theoretical Computer Science (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Lenses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062962723P | 2020-01-17 | 2020-01-17 | |
US202063076361P | 2020-09-09 | 2020-09-09 | |
PCT/US2021/013696 WO2021146597A1 (en) | 2020-01-17 | 2021-01-15 | High performance fluorescence imaging module for genomic testing assay |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202111573VA true SG11202111573VA (en) | 2021-11-29 |
Family
ID=76657985
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202111573VA SG11202111573VA (en) | 2020-01-17 | 2021-01-15 | High performance fluorescence imaging module for genomic testing assay |
SG10202112013QA SG10202112013QA (en) | 2020-01-17 | 2021-01-15 | High performance fluorescence imaging module for genomic testing assay |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202112013QA SG10202112013QA (en) | 2020-01-17 | 2021-01-15 | High performance fluorescence imaging module for genomic testing assay |
Country Status (12)
Country | Link |
---|---|
US (11) | US11053540B1 (ko) |
EP (5) | EP4060321A1 (ko) |
JP (2) | JP7223165B2 (ko) |
KR (2) | KR102538825B1 (ko) |
CN (5) | CN115369157A (ko) |
AU (3) | AU2021207987B2 (ko) |
CA (1) | CA3137050A1 (ko) |
DE (2) | DE202021001858U1 (ko) |
GB (8) | GB2598233B (ko) |
IL (4) | IL303164B1 (ko) |
SG (2) | SG11202111573VA (ko) |
WO (1) | WO2021146597A1 (ko) |
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AU2019392932B2 (en) | 2018-12-07 | 2023-11-02 | Element Biosciences, Inc. | Flow cell device and use thereof |
JP7124216B2 (ja) * | 2019-05-15 | 2022-08-23 | 株式会社日立ハイテク | 荷電粒子線装置 |
US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
US11053540B1 (en) | 2020-01-17 | 2021-07-06 | Element Biosciences, Inc. | High performance fluorescence imaging module for genomic testing assay |
US11198121B1 (en) | 2020-06-10 | 2021-12-14 | Element Biosciences, Inc. | Flow cell systems and devices |
US11637977B2 (en) * | 2020-07-15 | 2023-04-25 | Corephotonics Ltd. | Image sensors and sensing methods to obtain time-of-flight and phase detection information |
EP4121561A4 (en) | 2020-08-06 | 2024-04-17 | Singular Genomics Systems, Inc. | METHODS FOR IN SITU TRANSCRIPTOMICS AND PROTEOMICS |
EP4237581A1 (en) | 2020-10-30 | 2023-09-06 | Element Biosciences, Inc. | Reagents for massively parallel nucleic acid sequencing |
IL310281A (en) * | 2021-07-21 | 2024-03-01 | Element Biosciences Inc | Optical systems for nucleic acid sequencing and methods thereof |
US20230051226A1 (en) * | 2021-08-10 | 2023-02-16 | Mgi Tech Co., Ltd. | Flow cell imaging systems and methods, and flow cells and other substrates for use in the same |
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CN114966968B (zh) * | 2022-05-25 | 2023-09-05 | 上海理工大学 | 一种激光制备二氧化硅平面波导布拉格光栅的装置和方法 |
WO2023250364A1 (en) * | 2022-06-21 | 2023-12-28 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
CN115166960B (zh) * | 2022-07-19 | 2023-08-04 | 华南师范大学 | 一种用于定量fret显微成像的led激发光源及调光方法 |
US11872333B1 (en) | 2022-07-25 | 2024-01-16 | William M. Gosney | Cassette apparatus utilizing venting for processing of blood to remove pathogen cells therein |
US20240024555A1 (en) * | 2022-07-25 | 2024-01-25 | William M. Gosney | Apparatus for processing of blood to neutralize pathogen cells therein |
US20240024551A1 (en) * | 2022-07-25 | 2024-01-25 | William M. Gosney | Apparatus utilizing venting for processing of blood to remove pathogen cells therein |
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WO2024087080A1 (zh) * | 2022-10-27 | 2024-05-02 | 深圳华大智造科技股份有限公司 | 一种浸没物镜、光学系统及检测方法 |
CN115393364B (zh) * | 2022-11-01 | 2023-08-01 | 长春理工大学 | 一种化学发光印迹泳道识别方法 |
CN117388227B (zh) * | 2023-10-18 | 2024-05-31 | 博瑞生物医药(苏州)股份有限公司 | 使用检测微球测定样品中目标分子浓度的方法、计算机可读介质和分析设备 |
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