SG11202010785UA - Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use - Google Patents
Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical useInfo
- Publication number
- SG11202010785UA SG11202010785UA SG11202010785UA SG11202010785UA SG11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA
- Authority
- SG
- Singapore
- Prior art keywords
- crystalline form
- pharmaceutical use
- triethylenetetramine tetrahydrochloride
- tetrahydrochloride
- triethylenetetramine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/84—Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18290048 | 2018-05-04 | ||
| PCT/EP2019/061441 WO2019211464A1 (en) | 2018-05-04 | 2019-05-03 | Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202010785UA true SG11202010785UA (en) | 2020-11-27 |
Family
ID=62455418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202010785UA SG11202010785UA (en) | 2018-05-04 | 2019-05-03 | Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US10988436B2 (zh) |
| EP (1) | EP3652145A1 (zh) |
| JP (1) | JP2021531322A (zh) |
| KR (1) | KR20210005270A (zh) |
| CN (3) | CN119306616A (zh) |
| AR (1) | AR115080A1 (zh) |
| AU (2) | AU2019263969B2 (zh) |
| CA (1) | CA3096423A1 (zh) |
| CO (1) | CO2020013806A2 (zh) |
| DE (1) | DE19724752T1 (zh) |
| EA (1) | EA202092241A1 (zh) |
| ES (1) | ES2769049T1 (zh) |
| MA (2) | MA51919A1 (zh) |
| SA (1) | SA520420467B1 (zh) |
| SG (1) | SG11202010785UA (zh) |
| TW (1) | TW202002956A (zh) |
| WO (1) | WO2019211464A1 (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210005270A (ko) * | 2018-05-04 | 2021-01-13 | 오르파란 | 트리에틸렌테트라민 테트라클로라이드의 결정형 및 이의 약제학적 용도 |
| KR102489293B1 (ko) * | 2020-10-15 | 2023-01-17 | (주) 에프엔지리서치 | 공업용 등급의 트리에틸렌테트라민의 고순도 정제 방법 |
| AR125456A1 (es) | 2021-04-26 | 2023-07-19 | Orphalan S A | Control de la concentración de cobre no ligado a la ceruloplasmina |
| TWI819502B (zh) | 2022-02-23 | 2023-10-21 | 裕捷股份有限公司 | 一種三伸乙基四胺四氫氯化物及其製備方法與組合物 |
| CN116675607A (zh) * | 2022-02-23 | 2023-09-01 | 裕捷股份有限公司 | 一种三亚乙基四胺四氢氯化物及其制备方法与组合物 |
| WO2024018394A1 (en) * | 2022-07-19 | 2024-01-25 | Biophore India Pharmaceuticals Pvt. Ltd | A process for the preparation of crystalline form a of n, n'-bis(2-aminoethyl)-1,2-ethanediamine tetrahydrochloride |
| EP4487839A1 (en) | 2023-07-03 | 2025-01-08 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Pharmaceutical dosage form comprising trientine tetrahydrochloride, and method for preparing the same |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1078731A (en) | 1976-12-16 | 1980-06-03 | Charles E. Frosst And Co. | Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) |
| CS197093B1 (cs) * | 1978-06-16 | 1980-04-30 | Ivo Kuhr | Způsob přípravy čistého dihydrochloridu triethylentetraminu |
| DE19724752A1 (de) | 1997-04-24 | 1998-11-05 | Boehringer Mannheim Gmbh | Verwendung von Carbazolyl-(4)-oxy-propanolamin-Derivaten zur topischen Behandlung von Entzündungen und Wunden der Haut |
| EP1075254A2 (en) | 1998-04-03 | 2001-02-14 | Theodore Toney Ilenchuk | The use of polyamines in the treatment of dermatological symptoms |
| JP4369003B2 (ja) | 2000-02-23 | 2009-11-18 | ハリマ化成株式会社 | ハンダ付け用フラックス |
| DK1487431T3 (da) | 2002-03-08 | 2012-08-20 | Philera New Zealand Ltd | Forebyggelse og/eller behandling af cardiovaskulær sygdom og/eller dermed associeret hjertefejl |
| WO2003075910A1 (en) | 2002-03-08 | 2003-09-18 | Protemix Corporation Limited | Preventing and/or treating vascular disease, cardiomyopathy and/or associated heart failure |
| WO2004017957A1 (en) | 2002-08-20 | 2004-03-04 | Protemix Corporation Limited | Preventing and/or treating cardiovascular disease and/or associated heart failure |
| NZ545724A (en) | 2003-03-18 | 2007-11-30 | Protemix Corp Ltd | Use of a copper chelator for preventing and/or treating cardiovascular disease and/or associated heart failure |
| PT1778618E (pt) | 2004-07-19 | 2014-03-04 | Philera New Zealand Ltd | Síntese de trietilenotetraminas |
| CN105753719B (zh) * | 2014-12-17 | 2019-06-21 | 四川科瑞德凯华制药有限公司 | 一种盐酸曲恩汀化合物 |
| JP6326477B2 (ja) | 2015-12-25 | 2018-05-16 | 三洋化成工業株式会社 | 高分子凝集剤 |
| KR20210005270A (ko) * | 2018-05-04 | 2021-01-13 | 오르파란 | 트리에틸렌테트라민 테트라클로라이드의 결정형 및 이의 약제학적 용도 |
| WO2020006027A1 (en) | 2018-06-29 | 2020-01-02 | Sharp Laboratories Of America, Inc. | Ultra-reliability design for physical uplink control channel (pucch) in 5th generation (5g) new radio (nr) |
| CN109076617B (zh) | 2018-07-25 | 2022-08-19 | 北京小米移动软件有限公司 | Mtc系统的随机接入方法、装置及存储介质 |
| TWI819502B (zh) | 2022-02-23 | 2023-10-21 | 裕捷股份有限公司 | 一種三伸乙基四胺四氫氯化物及其製備方法與組合物 |
-
2019
- 2019-05-03 KR KR1020207035089A patent/KR20210005270A/ko active Search and Examination
- 2019-05-03 MA MA51919A patent/MA51919A1/fr unknown
- 2019-05-03 JP JP2021510544A patent/JP2021531322A/ja active Pending
- 2019-05-03 ES ES19724752T patent/ES2769049T1/es active Pending
- 2019-05-03 MA MA58726A patent/MA58726A1/fr unknown
- 2019-05-03 CN CN202411423442.7A patent/CN119306616A/zh active Pending
- 2019-05-03 SG SG11202010785UA patent/SG11202010785UA/en unknown
- 2019-05-03 EP EP19724752.1A patent/EP3652145A1/en active Pending
- 2019-05-03 CN CN202210100454.0A patent/CN114394904A/zh active Pending
- 2019-05-03 CA CA3096423A patent/CA3096423A1/en active Pending
- 2019-05-03 TW TW108115436A patent/TW202002956A/zh unknown
- 2019-05-03 DE DE19724752.1T patent/DE19724752T1/de active Pending
- 2019-05-03 EA EA202092241A patent/EA202092241A1/ru unknown
- 2019-05-03 AU AU2019263969A patent/AU2019263969B2/en active Active
- 2019-05-03 WO PCT/EP2019/061441 patent/WO2019211464A1/en active Application Filing
- 2019-05-03 CN CN201980006492.6A patent/CN111479798B/zh active Active
- 2019-05-06 AR ARP190101194A patent/AR115080A1/es unknown
-
2020
- 2020-06-30 US US16/917,266 patent/US10988436B2/en active Active
- 2020-11-03 SA SA520420467A patent/SA520420467B1/ar unknown
- 2020-11-04 CO CONC2020/0013806A patent/CO2020013806A2/es unknown
-
2021
- 2021-02-09 US US17/171,347 patent/US11117855B2/en active Active
- 2021-02-09 US US17/171,358 patent/US11072577B2/en active Active
- 2021-08-10 US US17/398,408 patent/US20220169594A1/en not_active Abandoned
-
2023
- 2023-11-03 US US18/386,906 patent/US20240360071A1/en active Pending
-
2024
- 2024-10-30 AU AU2024227767A patent/AU2024227767A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11117855B2 (en) | 2021-09-14 |
| CN111479798A (zh) | 2020-07-31 |
| US20200392068A1 (en) | 2020-12-17 |
| CO2020013806A2 (es) | 2021-01-29 |
| ES2769049T1 (es) | 2020-06-24 |
| US20210163398A1 (en) | 2021-06-03 |
| CN119306616A (zh) | 2025-01-14 |
| US10988436B2 (en) | 2021-04-27 |
| US20210188761A1 (en) | 2021-06-24 |
| US11072577B2 (en) | 2021-07-27 |
| EA202092241A1 (ru) | 2021-04-01 |
| BR112020018451A2 (pt) | 2020-12-29 |
| TW202002956A (zh) | 2020-01-16 |
| SA520420467B1 (ar) | 2024-04-28 |
| JP2021531322A (ja) | 2021-11-18 |
| US20240360071A1 (en) | 2024-10-31 |
| DE19724752T1 (de) | 2020-07-09 |
| AR115080A1 (es) | 2020-11-25 |
| WO2019211464A1 (en) | 2019-11-07 |
| EP3652145A1 (en) | 2020-05-20 |
| MA51919A1 (fr) | 2021-11-30 |
| CN114394904A (zh) | 2022-04-26 |
| CA3096423A1 (en) | 2019-11-07 |
| MA58726A1 (fr) | 2023-09-27 |
| AU2019263969B2 (en) | 2024-08-01 |
| KR20210005270A (ko) | 2021-01-13 |
| AU2019263969A1 (en) | 2020-10-22 |
| US20220169594A1 (en) | 2022-06-02 |
| AU2024227767A1 (en) | 2024-11-21 |
| CN111479798B (zh) | 2024-11-01 |
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