SG11202010785UA - Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use - Google Patents
Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical useInfo
- Publication number
- SG11202010785UA SG11202010785UA SG11202010785UA SG11202010785UA SG11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA SG 11202010785U A SG11202010785U A SG 11202010785UA
- Authority
- SG
- Singapore
- Prior art keywords
- crystalline form
- pharmaceutical use
- triethylenetetramine tetrahydrochloride
- tetrahydrochloride
- triethylenetetramine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/84—Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18290048 | 2018-05-04 | ||
| PCT/EP2019/061441 WO2019211464A1 (en) | 2018-05-04 | 2019-05-03 | Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202010785UA true SG11202010785UA (en) | 2020-11-27 |
Family
ID=62455418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202010785UA SG11202010785UA (en) | 2018-05-04 | 2019-05-03 | Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10988436B2 (en) |
| EP (1) | EP3652145A1 (en) |
| JP (1) | JP2021531322A (en) |
| KR (1) | KR20210005270A (en) |
| CN (2) | CN114394904A (en) |
| AR (1) | AR115080A1 (en) |
| AU (1) | AU2019263969A1 (en) |
| BR (1) | BR112020018451A2 (en) |
| CA (1) | CA3096423A1 (en) |
| CO (1) | CO2020013806A2 (en) |
| DE (1) | DE19724752T1 (en) |
| EA (1) | EA202092241A1 (en) |
| ES (1) | ES2769049T1 (en) |
| MA (2) | MA51919A1 (en) |
| SG (1) | SG11202010785UA (en) |
| TW (1) | TW202002956A (en) |
| WO (1) | WO2019211464A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114394904A (en) | 2018-05-04 | 2022-04-26 | 奥法兰股份公司 | Crystalline forms of triethylenetetramine tetrahydrochloride and their pharmaceutical use |
| KR102489293B1 (en) * | 2020-10-15 | 2023-01-17 | (주) 에프엔지리서치 | High purification of technical grade triethylenetetramine |
| EP4329738A1 (en) | 2021-04-26 | 2024-03-06 | Orphalan S.A. | Non-ceruloplasmin bound copper level monitoring |
| TWI819502B (en) * | 2022-02-23 | 2023-10-21 | 裕捷股份有限公司 | Triethylenetetramine tetrahydrochloride and its preparation method and composition |
| CN116675607A (en) * | 2022-02-23 | 2023-09-01 | 裕捷股份有限公司 | Triethylenetetramine tetrahydrochloride and preparation method and composition thereof |
| WO2024018394A1 (en) * | 2022-07-19 | 2024-01-25 | Biophore India Pharmaceuticals Pvt. Ltd | A process for the preparation of crystalline form a of n, n'-bis(2-aminoethyl)-1,2-ethanediamine tetrahydrochloride |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1078731A (en) | 1976-12-16 | 1980-06-03 | Charles E. Frosst And Co. | Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) |
| CS197093B1 (en) * | 1978-06-16 | 1980-04-30 | Ivo Kuhr | Process for preparing pure dihydtochloride of triethylentetramine |
| DE19724752A1 (en) | 1997-04-24 | 1998-11-05 | Boehringer Mannheim Gmbh | Use of carbazol-4-yl-oxy-propanol-amine derivative |
| EP1075254A2 (en) | 1998-04-03 | 2001-02-14 | Theodore Toney Ilenchuk | The use of polyamines in the treatment of dermatological symptoms |
| JP4369003B2 (en) | 2000-02-23 | 2009-11-18 | ハリマ化成株式会社 | Soldering flux |
| CA2478997C (en) | 2002-03-08 | 2013-12-17 | Protemix Corporation Limited | Use of copper chelating tetraamines for the treatment of cardiovascular disease and heart failure |
| WO2003075910A1 (en) | 2002-03-08 | 2003-09-18 | Protemix Corporation Limited | Preventing and/or treating vascular disease, cardiomyopathy and/or associated heart failure |
| AU2003214725A1 (en) | 2002-08-20 | 2004-03-11 | Protemix Corporation Limited | Preventing and/or treating cardiovascular disease and/or associated heart failure |
| NZ545724A (en) | 2003-03-18 | 2007-11-30 | Protemix Corp Ltd | Use of a copper chelator for preventing and/or treating cardiovascular disease and/or associated heart failure |
| CA2577634C (en) | 2004-07-19 | 2015-07-07 | Protemix Corporation Limited | Synthesis of triethylenetetramines |
| CN106278907B (en) * | 2014-12-17 | 2019-06-21 | 四川科瑞德凯华制药有限公司 | A kind of Syprine Hydrochloride compound |
| JP6326477B2 (en) | 2015-12-25 | 2018-05-16 | 三洋化成工業株式会社 | Polymer flocculant |
| CN114394904A (en) | 2018-05-04 | 2022-04-26 | 奥法兰股份公司 | Crystalline forms of triethylenetetramine tetrahydrochloride and their pharmaceutical use |
| WO2020006027A1 (en) | 2018-06-29 | 2020-01-02 | Sharp Laboratories Of America, Inc. | Ultra-reliability design for physical uplink control channel (pucch) in 5th generation (5g) new radio (nr) |
| CN109076617B (en) | 2018-07-25 | 2022-08-19 | 北京小米移动软件有限公司 | Random access method, device and storage medium of MTC (machine type communication) system |
| TWI819502B (en) | 2022-02-23 | 2023-10-21 | 裕捷股份有限公司 | Triethylenetetramine tetrahydrochloride and its preparation method and composition |
-
2019
- 2019-05-03 CN CN202210100454.0A patent/CN114394904A/en active Pending
- 2019-05-03 AU AU2019263969A patent/AU2019263969A1/en active Pending
- 2019-05-03 BR BR112020018451-9A patent/BR112020018451A2/en active IP Right Grant
- 2019-05-03 TW TW108115436A patent/TW202002956A/en unknown
- 2019-05-03 WO PCT/EP2019/061441 patent/WO2019211464A1/en active Application Filing
- 2019-05-03 SG SG11202010785UA patent/SG11202010785UA/en unknown
- 2019-05-03 CA CA3096423A patent/CA3096423A1/en active Pending
- 2019-05-03 EP EP19724752.1A patent/EP3652145A1/en active Pending
- 2019-05-03 MA MA51919A patent/MA51919A1/en unknown
- 2019-05-03 EA EA202092241A patent/EA202092241A1/en unknown
- 2019-05-03 KR KR1020207035089A patent/KR20210005270A/en active Search and Examination
- 2019-05-03 JP JP2021510544A patent/JP2021531322A/en active Pending
- 2019-05-03 CN CN201980006492.6A patent/CN111479798A/en active Pending
- 2019-05-03 DE DE19724752.1T patent/DE19724752T1/en active Pending
- 2019-05-03 MA MA58726A patent/MA58726A1/en unknown
- 2019-05-03 ES ES19724752T patent/ES2769049T1/en active Pending
- 2019-05-06 AR ARP190101194A patent/AR115080A1/en unknown
-
2020
- 2020-06-30 US US16/917,266 patent/US10988436B2/en active Active
- 2020-11-04 CO CONC2020/0013806A patent/CO2020013806A2/en unknown
-
2021
- 2021-02-09 US US17/171,347 patent/US11117855B2/en active Active
- 2021-02-09 US US17/171,358 patent/US11072577B2/en active Active
- 2021-08-10 US US17/398,408 patent/US20220169594A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20210188761A1 (en) | 2021-06-24 |
| CA3096423A1 (en) | 2019-11-07 |
| US10988436B2 (en) | 2021-04-27 |
| KR20210005270A (en) | 2021-01-13 |
| US20220169594A1 (en) | 2022-06-02 |
| CO2020013806A2 (en) | 2021-01-29 |
| ES2769049T1 (en) | 2020-06-24 |
| AU2019263969A1 (en) | 2020-10-22 |
| CN111479798A (en) | 2020-07-31 |
| MA51919A1 (en) | 2021-11-30 |
| JP2021531322A (en) | 2021-11-18 |
| EA202092241A1 (en) | 2021-04-01 |
| EP3652145A1 (en) | 2020-05-20 |
| US20200392068A1 (en) | 2020-12-17 |
| DE19724752T1 (en) | 2020-07-09 |
| AR115080A1 (en) | 2020-11-25 |
| TW202002956A (en) | 2020-01-16 |
| US11072577B2 (en) | 2021-07-27 |
| WO2019211464A1 (en) | 2019-11-07 |
| CN114394904A (en) | 2022-04-26 |
| US20210163398A1 (en) | 2021-06-03 |
| MA58726A1 (en) | 2023-09-27 |
| US11117855B2 (en) | 2021-09-14 |
| BR112020018451A2 (en) | 2020-12-29 |
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