SG11202007754UA - Heterocyclic compounds as kinase inhibitors - Google Patents
Heterocyclic compounds as kinase inhibitorsInfo
- Publication number
- SG11202007754UA SG11202007754UA SG11202007754UA SG11202007754UA SG11202007754UA SG 11202007754U A SG11202007754U A SG 11202007754UA SG 11202007754U A SG11202007754U A SG 11202007754UA SG 11202007754U A SG11202007754U A SG 11202007754UA SG 11202007754U A SG11202007754U A SG 11202007754UA
- Authority
- SG
- Singapore
- Prior art keywords
- kinase inhibitors
- heterocyclic compounds
- heterocyclic
- compounds
- kinase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862631437P | 2018-02-15 | 2018-02-15 | |
PCT/US2019/018244 WO2019161224A1 (en) | 2018-02-15 | 2019-02-15 | Heterocyclic compounds as kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202007754UA true SG11202007754UA (en) | 2020-09-29 |
Family
ID=67542098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202007754UA SG11202007754UA (en) | 2018-02-15 | 2019-02-15 | Heterocyclic compounds as kinase inhibitors |
Country Status (13)
Country | Link |
---|---|
US (2) | US11174252B2 (pt) |
EP (1) | EP3752491A4 (pt) |
JP (1) | JP2021514359A (pt) |
KR (1) | KR20200131246A (pt) |
CN (1) | CN112334451A (pt) |
AU (1) | AU2019220746A1 (pt) |
BR (1) | BR112020015431A2 (pt) |
CA (1) | CA3089592A1 (pt) |
IL (1) | IL276509A (pt) |
MA (1) | MA51846A (pt) |
MX (1) | MX2020008559A (pt) |
SG (1) | SG11202007754UA (pt) |
WO (1) | WO2019161224A1 (pt) |
Families Citing this family (24)
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RU2020124138A (ru) | 2017-12-22 | 2022-01-24 | Хиберселл, Инк. | Производные аминопиридина в качестве ингибиторов фосфатидилинозитолфосфаткиназы |
US11622966B2 (en) | 2018-05-25 | 2023-04-11 | A2A Pharmaceuticals, Inc. | Highly potent TACC3 inhibitor as a novel anticancer drug candidate |
TW202112767A (zh) | 2019-06-17 | 2021-04-01 | 美商佩特拉製藥公司 | 作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物 |
WO2021030620A1 (en) * | 2019-08-14 | 2021-02-18 | Nuvation Bio Inc. | Heterocyclic compounds as kinase inhibitors |
EP4013743A1 (en) * | 2019-08-14 | 2022-06-22 | Nuvation Bio Inc. | Heterocyclic compounds as kinase inhibitors |
CN113244386A (zh) * | 2020-02-13 | 2021-08-13 | 上海君实生物医药科技股份有限公司 | 抗pd-1抗体在治疗肿瘤中的用途 |
JP2023517519A (ja) * | 2020-03-02 | 2023-04-26 | シロナックス・リミテッド | フェロトーシス阻害剤ジアリールアミンパラアセトアミド類 |
WO2022078309A1 (zh) * | 2020-10-12 | 2022-04-21 | 上海海雁医药科技有限公司 | 取代的二(吡啶-2-基)胺衍生物、其组合物及医药上的用途 |
WO2022113003A1 (en) | 2020-11-27 | 2022-06-02 | Rhizen Pharmaceuticals Ag | Cdk inhibitors |
WO2022149057A1 (en) | 2021-01-05 | 2022-07-14 | Rhizen Pharmaceuticals Ag | Cdk inhibitors |
US20220259195A1 (en) * | 2021-02-03 | 2022-08-18 | Nuvation Bio Inc. | Crystalline forms of a cyclin-dependent kinase inhibitor |
CN117460724A (zh) * | 2021-04-12 | 2024-01-26 | A2A制药有限公司 | 用于治疗癌症的组合物和方法 |
WO2022236256A1 (en) * | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Heterocyclic compounds as kinase inhibitors |
WO2022236253A1 (en) * | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Heterocyclic compounds as kinase inhibitors |
WO2022236257A1 (en) * | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Heterocyclic compounds as kinase inhibitors |
WO2022236255A2 (en) * | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Heterocyclic compounds as kinase inhibitors |
CN113264920B (zh) * | 2021-05-10 | 2022-09-02 | 中国药科大学 | 一种嘧啶苯并六元环母核的cdk6抑制剂及其制备方法和应用 |
US20230000876A1 (en) * | 2021-06-09 | 2023-01-05 | Nuvation Bio Inc. | Treating cancers with a cyclin-dependent kinase inhibitor |
TW202400575A (zh) | 2022-03-24 | 2024-01-01 | 美商A2A製藥公司 | 治療癌症的組合物和方法 |
WO2023205892A1 (en) * | 2022-04-27 | 2023-11-02 | Risen (Suzhou) Pharma Tech Co., Ltd. | Cdk inhibitors and pharmaceutical uses thereof |
WO2023208172A1 (en) * | 2022-04-29 | 2023-11-02 | Beigene , Ltd. | Substituted 7- (pyrimidin-4-yl) quinolin-4 (1h) -one compounds as cyclin dependent kinase inhibitors |
WO2024022487A1 (en) * | 2022-07-29 | 2024-02-01 | Allorion Therapeutics Inc | Aminoheteroaryl kinase inhibitors |
WO2024051702A1 (zh) * | 2022-09-05 | 2024-03-14 | 浙江同源康医药股份有限公司 | 用作cdk4激酶抑制剂的化合物及其应用 |
WO2024107746A1 (en) * | 2022-11-15 | 2024-05-23 | Larkspur Biosciences | Inhibitors and degraders of pip4k protein |
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-
2019
- 2019-02-15 US US16/277,355 patent/US11174252B2/en active Active
- 2019-02-15 MA MA051846A patent/MA51846A/fr unknown
- 2019-02-15 CN CN201980025159.XA patent/CN112334451A/zh active Pending
- 2019-02-15 CA CA3089592A patent/CA3089592A1/en active Pending
- 2019-02-15 SG SG11202007754UA patent/SG11202007754UA/en unknown
- 2019-02-15 MX MX2020008559A patent/MX2020008559A/es unknown
- 2019-02-15 JP JP2020543494A patent/JP2021514359A/ja active Pending
- 2019-02-15 AU AU2019220746A patent/AU2019220746A1/en not_active Abandoned
- 2019-02-15 KR KR1020207026424A patent/KR20200131246A/ko not_active Application Discontinuation
- 2019-02-15 WO PCT/US2019/018244 patent/WO2019161224A1/en unknown
- 2019-02-15 BR BR112020015431-8A patent/BR112020015431A2/pt not_active Application Discontinuation
- 2019-02-15 EP EP19754726.8A patent/EP3752491A4/en not_active Withdrawn
-
2020
- 2020-08-05 IL IL276509A patent/IL276509A/en unknown
-
2021
- 2021-10-01 US US17/449,779 patent/US20230062022A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX2020008559A (es) | 2021-01-08 |
US20190248774A1 (en) | 2019-08-15 |
AU2019220746A1 (en) | 2020-08-27 |
US11174252B2 (en) | 2021-11-16 |
MA51846A (fr) | 2021-04-21 |
IL276509A (en) | 2020-09-30 |
KR20200131246A (ko) | 2020-11-23 |
EP3752491A4 (en) | 2021-12-01 |
US20230062022A1 (en) | 2023-03-02 |
WO2019161224A1 (en) | 2019-08-22 |
BR112020015431A2 (pt) | 2020-12-08 |
JP2021514359A (ja) | 2021-06-10 |
CA3089592A1 (en) | 2019-08-22 |
CN112334451A (zh) | 2021-02-05 |
EP3752491A1 (en) | 2020-12-23 |
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