SG11202006906XA - Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones - Google Patents
Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-onesInfo
- Publication number
- SG11202006906XA SG11202006906XA SG11202006906XA SG11202006906XA SG11202006906XA SG 11202006906X A SG11202006906X A SG 11202006906XA SG 11202006906X A SG11202006906X A SG 11202006906XA SG 11202006906X A SG11202006906X A SG 11202006906XA SG 11202006906X A SG11202006906X A SG 11202006906XA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrazolo
- pyrimidin
- dihydro
- ones
- substituted
- Prior art date
Links
- JTNQNHQPENYUGB-UHFFFAOYSA-N 1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one Chemical class C1=NC=C2C(O)=NNC2=N1 JTNQNHQPENYUGB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862641149P | 2018-03-09 | 2018-03-09 | |
| US201862755163P | 2018-11-02 | 2018-11-02 | |
| PCT/US2019/019557 WO2019173082A1 (en) | 2018-03-09 | 2019-02-26 | Substituted l,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202006906XA true SG11202006906XA (en) | 2020-09-29 |
Family
ID=67845731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202006906XA SG11202006906XA (en) | 2018-03-09 | 2019-02-26 | Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11261192B2 (zh) |
| EP (1) | EP3762385A4 (zh) |
| JP (2) | JP7300460B2 (zh) |
| KR (1) | KR20200130834A (zh) |
| CN (3) | CN117285532A (zh) |
| AU (2) | AU2019231551B2 (zh) |
| BR (1) | BR112020018286A2 (zh) |
| CA (1) | CA3089746A1 (zh) |
| IL (2) | IL276802B2 (zh) |
| MX (2) | MX2020009372A (zh) |
| NZ (1) | NZ766616A (zh) |
| SG (1) | SG11202006906XA (zh) |
| TW (1) | TWI822733B (zh) |
| WO (1) | WO2019173082A1 (zh) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11028058B2 (en) | 2017-07-18 | 2021-06-08 | Nuvation Bio Inc. | Heterocyclic compounds as adenosine antagonists |
| MX2020000693A (es) | 2017-07-18 | 2020-07-29 | Nuvation Bio Inc | Compuestos de 1,8-naftiridinona, y usos de los mismos. |
| AU2018347307A1 (en) | 2017-10-09 | 2020-04-23 | Nuvation Bio Inc. | Heterocyclic compounds and uses thereof |
| WO2019074979A1 (en) | 2017-10-09 | 2019-04-18 | Girafpharma, Llc | HETEROCYCLIC COMPOUNDS AND USES THEREOF |
| IL276802B2 (en) * | 2018-03-09 | 2023-09-01 | Recurium Ip Holdings Llc | Transduced 2,1-dihydro-3h-pyrazolo[4,3-d]pyrimidine-3-ones |
| CN113939291A (zh) | 2019-01-18 | 2022-01-14 | 诺维逊生物股份有限公司 | 1,8-萘啶酮化合物及其用途 |
| KR20210116550A (ko) | 2019-01-18 | 2021-09-27 | 누베이션 바이오 인크. | 아데노신 길항제로서의 헤테로시클릭 화합물 |
| EP3952876A4 (en) * | 2019-04-09 | 2023-04-19 | Nuvation Bio Inc. | HETEROCYCLIC COMPOUNDS AND USES THEREOF |
| MX2021012418A (es) | 2019-04-09 | 2021-11-12 | Nuvation Bio Inc | Compuestos heterociclicos y sus usos. |
| US20220220115A1 (en) * | 2019-04-09 | 2022-07-14 | Nuvation Bio Inc. | Heterocyclic compounds and uses thereof |
| WO2020210320A1 (en) * | 2019-04-11 | 2020-10-15 | Recurium Ip Holdings, Llc | Substituted l,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
| CN112142748B (zh) * | 2019-06-28 | 2023-07-04 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
| EP4045486A4 (en) * | 2019-11-15 | 2023-11-29 | Recurium IP Holdings, LLC | CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL |
| EP4069241A4 (en) * | 2019-12-20 | 2024-01-03 | Recurium IP Holdings, LLC | COMBINATIONS |
| WO2021127047A1 (en) * | 2019-12-20 | 2021-06-24 | Recurium Ip Holdings, Llc | Combinations |
| AU2020404996A1 (en) * | 2019-12-20 | 2022-07-14 | Recurium Ip Holdings, Llc | Combinations |
| WO2021127044A1 (en) * | 2019-12-20 | 2021-06-24 | Recurium Ip Holdings, Llc | Combinations |
| CN113387962A (zh) * | 2020-03-12 | 2021-09-14 | 上海迪诺医药科技有限公司 | 吡唑并[3,4-d]嘧啶-3-酮衍生物、其药物组合物及应用 |
| WO2021231653A1 (en) * | 2020-05-15 | 2021-11-18 | Recurium Ip Holdings, Llc | Mono- and combination therapies |
| JP2023530085A (ja) * | 2020-06-11 | 2023-07-13 | リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー | Ｗｅｅ１阻害剤化合物の作製方法 |
| EP4169919A4 (en) | 2020-06-17 | 2024-07-17 | Wigen Biomedicine Tech Shanghai Co Ltd | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE USED AS WEE-1 INHIBITOR |
| EP4178960A4 (en) * | 2020-07-09 | 2024-07-17 | Recurium Ip Holdings Llc | SALTS AND FORMS OF A WEE1 INHIBITOR |
| WO2022076638A1 (en) * | 2020-10-08 | 2022-04-14 | Academia Sinica | Catalysts and their uses in one-pot diastereoselective synthesis of remdesivir |
| WO2022171126A1 (zh) * | 2021-02-09 | 2022-08-18 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的稠环化合物 |
| CN116848118A (zh) * | 2021-02-09 | 2023-10-03 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的吡唑并[3,4-d]嘧啶-3-酮衍生物 |
| WO2022171088A1 (zh) * | 2021-02-09 | 2022-08-18 | 微境生物医药科技(上海)有限公司 | 吡唑并[3,4-d]嘧啶-3-酮衍生物 |
| WO2022221143A1 (en) * | 2021-04-12 | 2022-10-20 | Recurium Ip Holdings, Llc | Wee1 compound for treating uterine serous carcinoma |
| CN117222648A (zh) | 2021-04-30 | 2023-12-12 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的稠环化合物及其制备方法和用途 |
| WO2022251224A1 (en) * | 2021-05-28 | 2022-12-01 | Recurium Ip Holdings, Llc | Wee1 inhibitors and methods for treating cancer |
| AU2022299158A1 (en) * | 2021-06-23 | 2024-01-18 | Recurium Ip Holdings, Llc | Wee1 inhibitors and methods for treating cancer |
| CN117616029A (zh) * | 2021-07-05 | 2024-02-27 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的稠环化合物 |
| CN117751122A (zh) * | 2021-08-11 | 2024-03-22 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的1,2-二氢-3H-吡唑[3,4-d]嘧啶-3-酮化合物 |
| CN113735863A (zh) * | 2021-09-29 | 2021-12-03 | 武汉九州钰民医药科技有限公司 | Wee1抑制剂adavosertib的制备工艺 |
| WO2023072301A1 (zh) * | 2021-11-01 | 2023-05-04 | 正大天晴药业集团股份有限公司 | 吡唑[3,4-d]嘧啶-3-酮类化合物及其医药用途 |
| EP4431511A1 (en) * | 2021-11-09 | 2024-09-18 | Hangzhou Glubio Pharmaceutical Co. Ltd. | Wee1 protein kinase degradation agent and use thereof |
| WO2023193789A1 (en) * | 2022-04-08 | 2023-10-12 | Beijing Neox Biotech Limited | Wee1 degrading compounds |
| WO2024031048A1 (en) * | 2022-08-05 | 2024-02-08 | Recurium Ip Holdings, Llc | Wee1 compound for treating uterine serous carcinoma |
| TW202421151A (zh) * | 2022-09-16 | 2024-06-01 | 美商瑞卡瑞恩Ｉｐ控股有限責任公司 | Ｗｅｅ１抑制劑及用於治療癌症之方法 |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0414533A (pt) | 2003-09-18 | 2006-11-07 | Conforma Therapeutics Corp | composto, composição farmacêutica, e, métodos para inibir um hsp90 e para tratar um indivìduo tendo um distúrbio mediado por hsp90 |
| JP5136929B2 (ja) | 2004-03-24 | 2013-02-06 | アボット・ラボラトリーズ | 三環式ピラゾール系キナーゼ阻害薬 |
| US7507748B2 (en) | 2004-07-22 | 2009-03-24 | Amgen Inc. | Substituted aryl-amine derivatives and methods of use |
| WO2006064251A1 (en) | 2004-12-17 | 2006-06-22 | Astrazeneca Ab | 4- (4- (imidazol-4-yl) pyrimidin-2-ylamino) benzamides as cdk inhibitors |
| US20070105874A1 (en) | 2005-09-23 | 2007-05-10 | Conforma Therapeutics Corporation | Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors |
| AR060635A1 (es) | 2006-04-27 | 2008-07-02 | Banyu Pharma Co Ltd | Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer |
| RU2478635C2 (ru) | 2006-10-19 | 2013-04-10 | СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Гетероарильные соединения, содержащие их композиции и способы лечения с применением этих соединений |
| US20100003191A1 (en) | 2006-12-05 | 2010-01-07 | Nagasaki University | Aurone derivative-containing composition for diagnosis |
| MX2009006078A (es) | 2006-12-08 | 2009-09-18 | Takeda Pharmaceutical | Compuesto triciclico y su uso medico. |
| CA2703489A1 (en) * | 2007-10-23 | 2009-04-30 | Banyu Pharmaceutical Co., Ltd. | Pyridone-substituted-dihydropyrazolopyrimidinone derivative |
| WO2009076502A1 (en) | 2007-12-12 | 2009-06-18 | Wyeth | Methods for the preparation of hydroxy-substituted aryl sulfamide compounds |
| EP2350048A2 (en) | 2008-10-16 | 2011-08-03 | Schering Corporation | Azine derivatives and methods of use thereof |
| UY32622A (es) | 2009-05-12 | 2010-12-31 | Astrazeneca Ab | Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta) |
| US20110312996A1 (en) | 2010-05-17 | 2011-12-22 | Intermune, Inc. | Novel inhibitors of hepatitis c virus replication |
| DE102011108708A1 (de) | 2010-09-25 | 2012-03-29 | Merck Patent Gmbh | Flüssigkristallanzeigen und flüssigkristalline Medien mit homöotroper Ausrichtung |
| US9938269B2 (en) | 2011-06-30 | 2018-04-10 | Abbvie Inc. | Inhibitor compounds of phosphodiesterase type 10A |
| MY183661A (en) | 2011-10-19 | 2021-03-05 | Signal Pharm Llc | Treatment of cancer with tor kinase inhibitors |
| WO2014062454A1 (en) | 2012-10-15 | 2014-04-24 | Merck Sharp & Dohme Corp. | Compositions and methods for treating cancer |
| CN103864792B (zh) | 2012-12-12 | 2017-01-18 | 山东亨利医药科技有限责任公司 | 作为酪氨酸激酶抑制剂的含氮并环类化合物 |
| CA2902858A1 (en) | 2013-02-28 | 2014-09-04 | Signal Pharmaceuticals, Llc | Treatment of cancer with tor kinase inhibitors |
| TW201522332A (zh) | 2013-03-01 | 2015-06-16 | Amgen Inc | 經取代之７－酮基－吡啶并［２，３－ｄ］嘧啶及其使用方法 |
| EP2997109B1 (en) | 2013-05-14 | 2018-03-21 | Merck Patent GmbH | Liquid crystalline medium and liquid crystal device |
| JP6377245B2 (ja) | 2014-03-24 | 2018-08-22 | グアンドン ジョンシェン ファーマシューティカル カンパニー リミテッド | Ｓｍｏ阻害剤としてのキノリン誘導体 |
| WO2016022626A1 (en) | 2014-08-06 | 2016-02-11 | Merck Sharp & Dohme Corp. | Heterocyclic cgrp receptor antagonists |
| CN106687563B (zh) | 2014-09-05 | 2023-03-14 | 默克专利有限公司 | 制剂和电子器件 |
| WO2016138631A1 (en) | 2015-03-03 | 2016-09-09 | Eli Lilly And Company | Imidazo benzamide compounds |
| EP3368538B1 (en) * | 2015-11-01 | 2021-09-01 | The Regents of The University of Colorado, A Body Corporate | Wee 1 kinase inhibitors and methods of making and using the same |
| MX2018011105A (es) | 2016-03-16 | 2018-11-22 | Kura Oncology Inc | Inhibidores sustituidos de menina-mll y metodos de uso. |
| KR20170127101A (ko) | 2016-05-10 | 2017-11-21 | 삼성디스플레이 주식회사 | 유기 발광 소자 |
| EP3468500A4 (en) | 2016-06-09 | 2020-03-04 | Blinkbio Inc. | THERAPEUTIC PAYLOADS BASED ON SILANOLE |
| GB201612092D0 (en) | 2016-07-12 | 2016-08-24 | Almac Discovery Ltd | Pharmaceutical compounds |
| KR102673813B1 (ko) | 2016-11-04 | 2024-06-10 | 삼성전자주식회사 | 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 진단용 조성물 |
| KR20180073222A (ko) | 2016-12-22 | 2018-07-02 | 삼성전자주식회사 | 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 진단용 조성물 |
| JP6717457B2 (ja) | 2017-01-23 | 2020-07-01 | シージャーズォアン サガシティ ニュー ドラッグ デベロップメント カンパニー リミテッド | Ｗｅｅ１阻害剤としての１，２−ジヒドロ−３Ｈ−ピラゾロ［３，４−ｄ］ピリミジン−３−オン誘導体 |
| KR102390377B1 (ko) | 2017-03-02 | 2022-04-25 | 삼성전자주식회사 | 유기금속 화합물 및 이를 포함한 유기 발광 소자 |
| JP7140337B2 (ja) * | 2017-03-23 | 2022-09-21 | シャンハイ ドーァ ノボ ファーマテック カンパニー，リミティド | ピラゾロ［３，４－ｄ］ピリミジン－３－オンの大環状誘導体、その医薬組成物及び応用 |
| KR102496480B1 (ko) | 2017-04-25 | 2023-02-06 | 삼성전자주식회사 | 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 조성물 |
| US11101435B2 (en) | 2017-05-19 | 2021-08-24 | Arizona Board Of Regents On Behalf Of Arizona State University | Tetradentate platinum and palladium complexes based on biscarbazole and analogues |
| CN111094253B (zh) * | 2017-08-01 | 2023-08-29 | 里科瑞尔姆Ip控股有限责任公司 | 1,2-二氢-3H-吡唑并[3,4-d]嘧啶-3-酮类似物 |
| WO2019037678A1 (zh) * | 2017-08-24 | 2019-02-28 | 上海迪诺医药科技有限公司 | 吡唑并[3,4-d]嘧啶-3-酮衍生物、其药物组合物及应用 |
| WO2019074979A1 (en) | 2017-10-09 | 2019-04-18 | Girafpharma, Llc | HETEROCYCLIC COMPOUNDS AND USES THEREOF |
| WO2019096322A1 (zh) | 2017-11-20 | 2019-05-23 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
| CN111315747B (zh) | 2018-01-05 | 2023-05-02 | 四川科伦博泰生物医药股份有限公司 | 二氢吡唑酮并嘧啶类化合物及其制备方法和用途 |
| WO2019165204A1 (en) | 2018-02-23 | 2019-08-29 | Newave Pharmaceutical Inc. | 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidine-3-one compounds as inhibitors of wee-1 kinase |
| WO2019169065A2 (en) | 2018-02-28 | 2019-09-06 | The Regents Of The University Of Colorado, A Body Corporate | Wee1 kinase inhibitors and methods of treating cancer using the same |
| IL276802B2 (en) | 2018-03-09 | 2023-09-01 | Recurium Ip Holdings Llc | Transduced 2,1-dihydro-3h-pyrazolo[4,3-d]pyrimidine-3-ones |
| KR102637792B1 (ko) | 2018-03-22 | 2024-02-19 | 삼성디스플레이 주식회사 | 유기 발광 소자 및 이를 포함한 전자 장치 |
| CN108794484B (zh) | 2018-04-28 | 2020-04-24 | 北京施安泰医药技术开发有限公司 | [1,2,4]三唑并[4,3-a]吡嗪衍生物、其药物组合物、制备方法和应用 |
| CN108794493B (zh) | 2018-04-28 | 2020-04-24 | 北京施安泰医药技术开发有限公司 | 四氢吡咯并[2,1-h]蝶啶-6(5H)-酮衍生物、其药物组合物、制备方法和应用 |
| KR102328435B1 (ko) | 2018-09-11 | 2021-11-18 | 재단법인 대구경북첨단의료산업진흥재단 | 신규 피리도-피리미딘 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 단백질 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물 |
| CN109651337A (zh) | 2018-12-30 | 2019-04-19 | 瑞声科技（南京）有限公司 | 发光组合物及包含该发光组合物的发光层和电致发光器件 |
| KR20200113482A (ko) | 2019-03-25 | 2020-10-07 | 삼성전자주식회사 | 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 진단용 조성물 |
| WO2020210320A1 (en) | 2019-04-11 | 2020-10-15 | Recurium Ip Holdings, Llc | Substituted l,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
| CN112142748B (zh) | 2019-06-28 | 2023-07-04 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
| WO2021127047A1 (en) | 2019-12-20 | 2021-06-24 | Recurium Ip Holdings, Llc | Combinations |
| WO2021127044A1 (en) | 2019-12-20 | 2021-06-24 | Recurium Ip Holdings, Llc | Combinations |
| AU2020404996A1 (en) | 2019-12-20 | 2022-07-14 | Recurium Ip Holdings, Llc | Combinations |
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2019
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- 2019-02-26 WO PCT/US2019/019557 patent/WO2019173082A1/en active Application Filing
- 2019-02-26 CA CA3089746A patent/CA3089746A1/en active Pending
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- 2019-02-26 BR BR112020018286-9A patent/BR112020018286A2/pt unknown
- 2019-02-26 KR KR1020207028226A patent/KR20200130834A/ko not_active Application Discontinuation
- 2019-02-26 CN CN202311229341.1A patent/CN117720541A/zh active Pending
- 2019-02-26 SG SG11202006906XA patent/SG11202006906XA/en unknown
- 2019-02-26 EP EP19764330.7A patent/EP3762385A4/en active Pending
- 2019-02-26 NZ NZ766616A patent/NZ766616A/en unknown
- 2019-02-26 IL IL302171A patent/IL302171A/en unknown
- 2019-02-26 US US16/971,254 patent/US11261192B2/en active Active
- 2019-02-26 MX MX2020009372A patent/MX2020009372A/es unknown
- 2019-02-26 JP JP2020547089A patent/JP7300460B2/ja active Active
- 2019-02-26 CN CN201980021575.2A patent/CN111902413B/zh active Active
- 2019-03-04 TW TW108107026A patent/TWI822733B/zh active
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2020
- 2020-09-08 MX MX2023010806A patent/MX2023010806A/es unknown
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2021
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2023
- 2023-06-19 JP JP2023100100A patent/JP2023113969A/ja active Pending
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Also Published As
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|---|---|
| AU2019231551B2 (en) | 2023-08-03 |
| CN117285532A (zh) | 2023-12-26 |
| WO2019173082A8 (en) | 2019-10-17 |
| IL276802B2 (en) | 2023-09-01 |
| EP3762385A1 (en) | 2021-01-13 |
| AU2019231551A8 (en) | 2020-09-24 |
| NZ766616A (en) | 2024-05-31 |
| MX2020009372A (es) | 2020-10-14 |
| JP7300460B2 (ja) | 2023-06-29 |
| CN117720541A (zh) | 2024-03-19 |
| TWI822733B (zh) | 2023-11-21 |
| KR20200130834A (ko) | 2020-11-20 |
| WO2019173082A1 (en) | 2019-09-12 |
| CA3089746A1 (en) | 2019-09-12 |
| AU2023251425A1 (en) | 2023-11-09 |
| IL276802A (en) | 2020-10-29 |
| JP2021516242A (ja) | 2021-07-01 |
| MX2023010806A (es) | 2023-09-27 |
| US20220024939A1 (en) | 2022-01-27 |
| US20210139482A1 (en) | 2021-05-13 |
| CN111902413A (zh) | 2020-11-06 |
| IL302171A (en) | 2023-06-01 |
| EP3762385A4 (en) | 2021-11-24 |
| AU2019231551A1 (en) | 2020-08-20 |
| TW202003512A (zh) | 2020-01-16 |
| JP2023113969A (ja) | 2023-08-16 |
| RU2020126590A (ru) | 2022-04-11 |
| IL276802B1 (en) | 2023-05-01 |
| TW202409033A (zh) | 2024-03-01 |
| CN111902413B (zh) | 2023-10-17 |
| BR112020018286A2 (pt) | 2020-12-29 |
| US11261192B2 (en) | 2022-03-01 |
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