SG11202006157VA - Methods for treating il-6 mediated inflammation without immunosuppression - Google Patents
Methods for treating il-6 mediated inflammation without immunosuppressionInfo
- Publication number
- SG11202006157VA SG11202006157VA SG11202006157VA SG11202006157VA SG11202006157VA SG 11202006157V A SG11202006157V A SG 11202006157VA SG 11202006157V A SG11202006157V A SG 11202006157VA SG 11202006157V A SG11202006157V A SG 11202006157VA SG 11202006157V A SG11202006157V A SG 11202006157VA
- Authority
- SG
- Singapore
- Prior art keywords
- immunosuppression
- treating
- methods
- mediated inflammation
- inflammation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862614134P | 2018-01-05 | 2018-01-05 | |
PCT/US2019/012430 WO2019136312A1 (en) | 2018-01-05 | 2019-01-04 | Methods for treating il-6 mediated inflammation without immunosuppression |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202006157VA true SG11202006157VA (en) | 2020-07-29 |
Family
ID=67143789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202006157VA SG11202006157VA (en) | 2018-01-05 | 2019-01-04 | Methods for treating il-6 mediated inflammation without immunosuppression |
Country Status (20)
Country | Link |
---|---|
US (4) | US20190241650A1 (ja) |
EP (1) | EP3735421A4 (ja) |
JP (2) | JP7395479B2 (ja) |
KR (2) | KR20230047223A (ja) |
CN (1) | CN111787950A (ja) |
AU (1) | AU2019205936B2 (ja) |
BR (1) | BR112020013519A2 (ja) |
CA (1) | CA3087699A1 (ja) |
CL (2) | CL2020001790A1 (ja) |
CO (1) | CO2020009510A2 (ja) |
EA (1) | EA202091640A1 (ja) |
IL (1) | IL275696A (ja) |
MA (1) | MA51584A (ja) |
MX (1) | MX2020006882A (ja) |
PE (1) | PE20211196A1 (ja) |
PH (1) | PH12020551040A1 (ja) |
RU (1) | RU2020125805A (ja) |
SG (1) | SG11202006157VA (ja) |
WO (1) | WO2019136312A1 (ja) |
ZA (1) | ZA202004074B (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018214554C1 (en) | 2017-02-01 | 2022-12-15 | Novo Nordisk A/S | Treatment of diuretic resistance |
JP7395479B2 (ja) | 2018-01-05 | 2023-12-11 | ノヴォ ノルディスク アー/エス | 免疫抑制なしにil-6媒介性炎症を処置する方法 |
MA54861A (fr) * | 2019-01-31 | 2021-12-08 | Regeneron Pharma | Anticorps anti-récepteur de l'il6 pour traiter l'arthrite idiopathique juvénile |
MA55809A (fr) | 2019-05-01 | 2022-03-09 | Novo Nordisk As | Formulation d'anticorps anti-il-6 |
EP3870261B1 (en) | 2019-12-13 | 2024-01-31 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
AR122933A1 (es) * | 2020-07-10 | 2022-10-19 | Novo Nordisk As | Métodos para tratar la enfermedad cardiovascular |
WO2022167916A1 (en) * | 2021-02-03 | 2022-08-11 | Novartis Ag | Use of il-1b binding antibodies for treating neuroinflammatory disorders |
JP7132665B1 (ja) * | 2022-02-25 | 2022-09-07 | 株式会社 バイオミメティクスシンパシーズ | 腫瘍を縮小又は消失させるための組成物 |
Family Cites Families (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0399429A1 (en) | 1989-05-22 | 1990-11-28 | Toray Industries, Inc. | Anti-human interleukin-6 monoclonal antibody |
JP2881311B2 (ja) | 1989-07-28 | 1999-04-12 | 味の素株式会社 | 抗ヒトbcdfモノクローナル抗体及びそれを用いたヒトbcdfの定量法 |
TW458985B (en) | 1993-05-31 | 2001-10-11 | Chugai Pharmaceutical Co Ltd | Reconstructed human antibody against human interleukin-6 |
US5888510A (en) | 1993-07-21 | 1999-03-30 | Chugai Seiyaku Kabushiki Kaisha | Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component |
JP3783873B2 (ja) | 1994-06-07 | 2006-06-07 | 中外製薬株式会社 | 肺における類線維素形成又は血栓形成に起因する疾患の予防及び治療薬並びに該疾患のモデル動物 |
US8017121B2 (en) | 1994-06-30 | 2011-09-13 | Chugai Seiyaku Kabushika Kaisha | Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component |
JPH1066582A (ja) | 1996-08-27 | 1998-03-10 | Tosoh Corp | Il−6のヘリックスd領域を認識する抗体の遺伝子断片等 |
ATE383875T1 (de) | 1998-03-17 | 2008-02-15 | Chugai Pharmaceutical Co Ltd | Prophylaktische oder therapeutische mittel gegen entzündliche erkrankungen des verdauungstraktes enthaltend antagonistische il-6 rezeptor antikörper |
US6395273B1 (en) | 1998-06-10 | 2002-05-28 | Promega Corporation | Prevention and treatment of inflammatory bowel disease |
WO2000066151A1 (en) * | 1999-04-29 | 2000-11-09 | Novo Nordisk A/S | Use of heparin-binding antagonists in the inhibition of bradykinin release |
US7163681B2 (en) | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
WO2002036164A1 (fr) | 2000-10-27 | 2002-05-10 | Chugai Seiyaku Kabushiki Kaisha | Agent abaissant le taux sanguin de vegf contenant un antagoniste de il-6 en tant que principe actif |
ES2727425T3 (es) | 2000-12-12 | 2019-10-16 | Medimmune Llc | Moléculas con semividas prolongadas, composiciones y usos de las mismas |
US7658921B2 (en) | 2000-12-12 | 2010-02-09 | Medimmune, Llc | Molecules with extended half-lives, compositions and uses thereof |
US7345048B2 (en) | 2001-06-28 | 2008-03-18 | Pliva D.D. | Heterocyclic compounds and uses thereof as D-alanyl-D-alanine ligase inhibitors |
EP2308888B1 (en) | 2001-11-14 | 2017-03-01 | Janssen Biotech, Inc. | Anti-IL-6 antibodies, compositions, methods and uses |
EP1456347A4 (en) | 2001-11-16 | 2006-08-02 | Human Genome Sciences Inc | ANTIBODIES BINDING TO BLYS ACCORDING TO AN IMMUNOSPECIFIC MODE |
FR2833011B1 (fr) | 2001-12-04 | 2004-10-29 | Univ Claude Bernard Lyon | Nouvelle proteine a activite inhibitrice de l'il-6 |
EP2366718A3 (en) | 2002-06-28 | 2012-05-02 | Domantis Limited | Ligand |
US20060078533A1 (en) | 2004-10-12 | 2006-04-13 | Omoigui Osemwota S | Method of prevention and treatment of aging and age-related disorders including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimer's disease and cancer |
US20060275294A1 (en) | 2002-08-22 | 2006-12-07 | Omoigui Osemwota S | Method of prevention and treatment of aging, age-related disorders and/or age-related manifestations including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimers disease and cancer |
KR100442281B1 (ko) | 2002-08-26 | 2004-08-02 | 엘지전자 주식회사 | 홈 네트워크 시스템의 제어 방법 |
CN1678744B (zh) | 2002-08-30 | 2010-05-26 | 财团法人化学及血清疗法研究所 | 人的抗人白细胞介素-6抗体以及所述抗体的片段 |
AU2003290682A1 (en) | 2002-11-15 | 2004-06-15 | Centocor, Inc. | Anti-angiogenic uses of il-6 antagonists |
ZA200507757B (en) | 2003-04-04 | 2007-01-31 | Genentech Inc | High concentration antibody and protein formulations |
WO2005028514A1 (en) | 2003-09-22 | 2005-03-31 | Biovation Gmbh & Co. Kg. | Use of a compound for reducing the biological effectiveness of il-6 |
ATE464908T1 (de) | 2004-02-11 | 2010-05-15 | Warner Lambert Co | Verfahren zur behandlung von osteoarthritis mit anti-il-6 antikörpern |
WO2006072954A2 (en) | 2005-01-05 | 2006-07-13 | Compugen Ltd. | Novel il-6 polynucleotides encoding variant il-6 polypeptides and methods using same |
PE20061324A1 (es) | 2005-04-29 | 2007-01-15 | Centocor Inc | Anticuerpos anti-il-6, composiciones, metodos y usos |
EP2007814A2 (en) | 2005-05-20 | 2008-12-31 | Ablynx N.V. | Single domain vhh antibodies against von willebrand factor |
ES2523666T3 (es) | 2005-05-31 | 2014-11-28 | Board Of Regents, The University Of Texas System | Anticuerpos IgG1 con la parte Fc mutada para el aumento de unión al receptor FcRn y usos de los mismos |
AR057582A1 (es) | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
WO2007061029A1 (ja) | 2005-11-25 | 2007-05-31 | Keio University | 前立腺癌治療剤 |
KR101422523B1 (ko) | 2005-12-09 | 2014-07-24 | 유씨비 파마, 에스.에이. | 사람 il6에 특이성을 지니는 항체 분자 |
JP5231810B2 (ja) | 2005-12-28 | 2013-07-10 | 中外製薬株式会社 | 抗体含有安定化製剤 |
DK1966244T3 (da) | 2005-12-30 | 2012-04-23 | Merck Patent Gmbh | Anti-il-6-antistoffer der forebygger bindingen af il-6 sammensat af il-6ralfa til gp130 |
US20110059101A9 (en) | 2006-03-13 | 2011-03-10 | Ablynx N.V. | Amino Acid Sequences Directed Against Il-6 And Polypetides Comprising The Same For The Treatment Of Diseases And Disorders Associated With Il-6 Mediated Signalling |
US7504106B2 (en) | 2006-03-14 | 2009-03-17 | Boris Skurkovich | Method and composition for treatment of renal failure with antibodies and their equivalents as partial or complete replacement for dialysis |
US7919095B2 (en) | 2006-08-03 | 2011-04-05 | Vaccinex, Inc. | Anti-IL-6 monoclonal antibodies |
US20100129354A1 (en) | 2006-10-27 | 2010-05-27 | Ablynx N.V. | Intranasal delivery of polypeptides and proteins |
CA2670583A1 (en) | 2006-11-30 | 2008-06-05 | Medimmune, Llc | Antibodies specific for the complex of interleukin-6 and the interleukin-6 receptor |
TW200831528A (en) | 2006-11-30 | 2008-08-01 | Astrazeneca Ab | Compounds |
JP4966647B2 (ja) | 2006-12-27 | 2012-07-04 | 矢崎総業株式会社 | 電気接続箱のシール構造 |
AR064826A1 (es) | 2007-01-09 | 2009-04-29 | Wyeth Corp | Formulaciones de anticuerpos anti-il-13 y usos de los mismos. dispositivos, parche y jeringa |
EP2703011A3 (en) | 2007-05-07 | 2014-03-26 | MedImmune, LLC | Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
TWI609965B (zh) | 2007-05-21 | 2018-01-01 | 艾爾德生物控股有限責任公司 | 新穎兔抗體人化方法以及經人化之兔抗體 |
US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
NZ597767A (en) | 2007-05-21 | 2013-06-28 | Bristol Myers Squibb Co | Antibodies to IL-6 and use thereof |
US20090238825A1 (en) | 2007-05-21 | 2009-09-24 | Kovacevich Brian R | Novel rabbit antibody humanization methods and humanized rabbit antibodies |
US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
WO2008156807A2 (en) | 2007-06-19 | 2008-12-24 | The Johns Hopkins University | Antithrombotic agents and methods of use thereof |
US20110008329A1 (en) | 2007-06-26 | 2011-01-13 | Medlmmune, Llc | Methods of Treating RSV Infections And Related Conditions |
US9884899B2 (en) | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
CA2734577A1 (en) | 2007-08-16 | 2009-02-26 | Carnegie Mellon University | Inflammation-regulating compositions and methods |
US20100203009A1 (en) | 2007-10-02 | 2010-08-12 | The Uab Research Foundation | Pathway for Th-17 Cell Development and Methods Utilizing Same |
PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
JP2011520898A (ja) | 2008-05-13 | 2011-07-21 | ノビミューン エスアー | 抗il−6/il−6r抗体およびそれらの使用方法 |
US8277804B2 (en) | 2008-05-21 | 2012-10-02 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
US8188235B2 (en) * | 2008-06-18 | 2012-05-29 | Pfizer Inc. | Antibodies to IL-6 and their uses |
TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
US9452227B2 (en) | 2008-11-25 | 2016-09-27 | Alderbio Holdings Llc | Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments |
KR20110112307A (ko) | 2008-11-25 | 2011-10-12 | 앨더 바이오파마슈티컬즈, 인코포레이티드 | 알부민을 상승시키고 및/또는 crp를 낮추는 il6의 길항제 |
US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
RU2650594C1 (ru) | 2009-01-29 | 2018-04-17 | Медиммун, Ллк | Человеческие анти-il-6 антитела с пролонгированным периодом выведения in vivo и их применение при лечении онкологических, аутоиммунных заболеваний и воспалительных заболеваний |
CN102740888B (zh) | 2009-11-24 | 2016-10-12 | 奥尔德生物制药公司 | Il-6抗体及其用途 |
JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
WO2012012531A2 (en) | 2010-07-20 | 2012-01-26 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods featuring il-6 and il-21 antagonists |
SG189220A1 (en) | 2010-10-06 | 2013-05-31 | Regeneron Pharma | Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies |
TWI603738B (zh) * | 2010-11-08 | 2017-11-01 | 建南德克公司 | 皮下投予抗-il-6受體抗體 |
US20120189621A1 (en) | 2011-01-21 | 2012-07-26 | Yann Dean | Combination Therapies and Methods Using Anti-CD3 Modulating Agents and Anti-IL-6 Antagonists |
CA2827581A1 (en) | 2011-03-03 | 2012-09-07 | Apexigen, Inc. | Anti-il-6 receptor antibodies and methods of use |
WO2013175276A1 (en) | 2012-05-23 | 2013-11-28 | Argen-X B.V | Il-6 binding molecules |
PE20151434A1 (es) | 2012-10-22 | 2015-10-16 | Stealth Peptides Int Inc | Metodos para la reduccion de los riesgos asociados con el insuficiencia cardiaca y factores asociados con el mismo |
MX2015004668A (es) | 2012-10-25 | 2015-07-23 | Medimmune Llc | Formulacion estable de anticuerpos de baja viscosidad. |
SG10201608703SA (en) | 2012-11-08 | 2016-12-29 | Eleven Biotherapeutics Inc | Il-6 antagonists and uses thereof |
MX2020005126A (es) | 2012-11-08 | 2022-01-27 | Clearside Biomedical Inc | Metodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos. |
BR112015022123B1 (pt) | 2013-03-15 | 2022-08-09 | Intrinsic Lifesciences, Llc | Anticorpos, fragmentos de ligação ao antígeno dos mesmos que se ligam especificamente à hepcidina ou um peptídeo de hepcidina, uso, meio contentor e kit |
RU2714919C2 (ru) * | 2013-08-30 | 2020-02-21 | Такеда Гмбх | Антитела, нейтрализующие gm-csf, для применения в лечении ревматоидного артрита или в качестве анальгетиков |
US20160130340A1 (en) | 2013-10-07 | 2016-05-12 | Alderbio Holdings Llc | Dosing regimens using anti-il-6 antibodies for the treatment of rheumatoid and psoriatic arthritis |
US8945560B1 (en) | 2014-07-15 | 2015-02-03 | Kymab Limited | Method of treating rheumatoid arthritis using antibody to IL6R |
US9017678B1 (en) | 2014-07-15 | 2015-04-28 | Kymab Limited | Method of treating rheumatoid arthritis using antibody to IL6R |
US9139648B1 (en) | 2014-07-15 | 2015-09-22 | Kymab Limited | Precision medicine by targeting human NAV1.9 variants for treatment of pain |
UY36449A (es) | 2014-12-19 | 2016-07-29 | Novartis Ag | Composiciones y métodos para anticuerpos dirigidos a bmp6 |
SG10201913062SA (en) | 2015-07-31 | 2020-03-30 | Medimmune Ltd | Methods for treating hepcidin-mediated disorders |
AU2018214554C1 (en) | 2017-02-01 | 2022-12-15 | Novo Nordisk A/S | Treatment of diuretic resistance |
JP7395479B2 (ja) | 2018-01-05 | 2023-12-11 | ノヴォ ノルディスク アー/エス | 免疫抑制なしにil-6媒介性炎症を処置する方法 |
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2019
- 2019-01-04 JP JP2020536963A patent/JP7395479B2/ja active Active
- 2019-01-04 KR KR1020237010971A patent/KR20230047223A/ko not_active Application Discontinuation
- 2019-01-04 KR KR1020207021357A patent/KR20200116089A/ko active Application Filing
- 2019-01-04 PE PE2020000914A patent/PE20211196A1/es unknown
- 2019-01-04 EA EA202091640A patent/EA202091640A1/ru unknown
- 2019-01-04 CA CA3087699A patent/CA3087699A1/en active Pending
- 2019-01-04 EP EP19735844.3A patent/EP3735421A4/en active Pending
- 2019-01-04 CN CN201980014573.0A patent/CN111787950A/zh active Pending
- 2019-01-04 SG SG11202006157VA patent/SG11202006157VA/en unknown
- 2019-01-04 MX MX2020006882A patent/MX2020006882A/es unknown
- 2019-01-04 RU RU2020125805A patent/RU2020125805A/ru unknown
- 2019-01-04 AU AU2019205936A patent/AU2019205936B2/en active Active
- 2019-01-04 WO PCT/US2019/012430 patent/WO2019136312A1/en unknown
- 2019-01-04 MA MA051584A patent/MA51584A/fr unknown
- 2019-01-04 US US16/240,670 patent/US20190241650A1/en not_active Abandoned
- 2019-01-04 BR BR112020013519-4A patent/BR112020013519A2/pt unknown
- 2019-04-26 US US16/396,378 patent/US11384143B2/en active Active
-
2020
- 2020-06-28 IL IL275696A patent/IL275696A/en unknown
- 2020-07-03 ZA ZA2020/04074A patent/ZA202004074B/en unknown
- 2020-07-03 CL CL2020001790A patent/CL2020001790A1/es unknown
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BR112020013519A2 (pt) | 2020-12-01 |
PE20211196A1 (es) | 2021-07-01 |
JP2021509668A (ja) | 2021-04-01 |
US20220227856A1 (en) | 2022-07-21 |
US20190248886A1 (en) | 2019-08-15 |
CA3087699A1 (en) | 2019-07-11 |
CL2020001790A1 (es) | 2021-03-19 |
JP2023168447A (ja) | 2023-11-24 |
MX2020006882A (es) | 2020-09-07 |
US11384143B2 (en) | 2022-07-12 |
AU2019205936A1 (en) | 2020-07-23 |
IL275696A (en) | 2020-08-31 |
JP7395479B2 (ja) | 2023-12-11 |
MA51584A (fr) | 2020-11-11 |
US20190241650A1 (en) | 2019-08-08 |
EP3735421A1 (en) | 2020-11-11 |
PH12020551040A1 (en) | 2021-08-23 |
WO2019136312A1 (en) | 2019-07-11 |
KR20200116089A (ko) | 2020-10-08 |
CN111787950A (zh) | 2020-10-16 |
CL2023001681A1 (es) | 2023-12-15 |
EP3735421A4 (en) | 2021-09-22 |
AU2019205936B2 (en) | 2022-09-15 |
ZA202004074B (en) | 2022-03-30 |
CO2020009510A2 (es) | 2020-10-30 |
EA202091640A1 (ru) | 2020-10-26 |
RU2020125805A (ru) | 2022-02-07 |
KR20230047223A (ko) | 2023-04-06 |
US20230090473A1 (en) | 2023-03-23 |
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