SG11201901937WA - Pyridine compound - Google Patents

Pyridine compound

Info

Publication number
SG11201901937WA
SG11201901937WA SG11201901937WA SG11201901937WA SG11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA
Authority
SG
Singapore
Prior art keywords
chuo
tokyo
limited
international
honcho
Prior art date
Application number
SG11201901937WA
Other languages
English (en)
Inventor
Hiroaki Inagaki
Yoshihiro Shibata
Hidenori Namiki
Hideaki Kageji
Kiyoshi Nakayama
Yasuyuki Kaneta
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of SG11201901937WA publication Critical patent/SG11201901937WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
SG11201901937WA 2016-09-29 2017-09-28 Pyridine compound SG11201901937WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016191725A JP2018052878A (ja) 2016-09-29 2016-09-29 ピリジン化合物
PCT/GB2017/052913 WO2018060714A1 (en) 2016-09-29 2017-09-28 Pyridine compound

Publications (1)

Publication Number Publication Date
SG11201901937WA true SG11201901937WA (en) 2019-04-29

Family

ID=60020249

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901937WA SG11201901937WA (en) 2016-09-29 2017-09-28 Pyridine compound

Country Status (32)

Country Link
US (2) US10851092B2 (ro)
EP (2) EP3519398B1 (ro)
JP (2) JP2018052878A (ro)
KR (1) KR102520543B1 (ro)
CN (2) CN113788824A (ro)
AU (2) AU2017335242C1 (ro)
BR (1) BR112019006047A2 (ro)
CA (1) CA3035860A1 (ro)
CL (1) CL2019000844A1 (ro)
CO (1) CO2019004034A2 (ro)
CY (1) CY1123988T1 (ro)
DK (1) DK3519398T3 (ro)
EA (1) EA037103B1 (ro)
EC (1) ECSP19030134A (ro)
ES (1) ES2868748T3 (ro)
HR (1) HRP20210447T1 (ro)
HU (1) HUE054824T2 (ro)
IL (1) IL265630B (ro)
LT (1) LT3519398T (ro)
MA (2) MA46337B1 (ro)
MD (1) MD3519398T2 (ro)
MX (1) MX2019003747A (ro)
PE (1) PE20190805A1 (ro)
PH (1) PH12019500480A1 (ro)
PL (1) PL3519398T3 (ro)
PT (1) PT3519398T (ro)
RS (1) RS61640B1 (ro)
SG (1) SG11201901937WA (ro)
SI (1) SI3519398T1 (ro)
UA (1) UA123964C2 (ro)
WO (1) WO2018060714A1 (ro)
ZA (1) ZA201902232B (ro)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY194262A (en) 2015-11-02 2022-11-25 Blueprint Medicines Corp Inhibitors of ret
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物
WO2019143994A1 (en) 2018-01-18 2019-07-25 Array Biopharma Inc. Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors
CN111971286B (zh) 2018-01-18 2023-04-14 阿雷生物药品公司 作为RET激酶抑制剂的取代的吡咯并[2,3-d]嘧啶化合物
JP7422084B2 (ja) 2018-04-03 2024-01-25 ブループリント メディシンズ コーポレイション Ret変化を有する癌の処置において使用するためのret阻害剤
CA3129665A1 (en) 2019-03-21 2020-09-24 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer
CN114761006A (zh) 2019-11-08 2022-07-15 Inserm(法国国家健康医学研究院) 对激酶抑制剂产生耐药性的癌症的治疗方法
CN115087463A (zh) * 2019-11-18 2022-09-20 中外制药株式会社 并用药物
CN113121524B (zh) 2019-12-31 2023-04-25 南京创济生物医药有限公司 杂环亚砜亚胺化合物及其中间体、制备方法和应用
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
WO2021164742A1 (zh) * 2020-02-20 2021-08-26 广州白云山医药集团股份有限公司白云山制药总厂 喹啉类化合物
WO2021164741A1 (zh) * 2020-02-20 2021-08-26 南京明德新药研发有限公司 苯基双酰胺类化合物
WO2022238706A1 (en) 2021-05-14 2022-11-17 Bp Asset Viii, Inc. Ret inhibitor for the treatment of ret altered medullary thyroid cancer or ret altered non-small cell lung cancer
AU2022463015A1 (en) 2021-10-22 2024-05-09 Tract Pharmaceuticals, Inc. Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues
CN115090331B (zh) * 2022-07-21 2023-05-16 扬州大学 超分子手性催化剂、其制备方法及其催化d-a反应的应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
AU2004270733B2 (en) 2003-09-11 2011-05-19 Itherx Pharma, Inc. Cytokine inhibitors
US20090076075A1 (en) 2006-03-02 2009-03-19 Frederic Henri Jung Quinoline derivatives
JP2009528335A (ja) 2006-03-02 2009-08-06 アストラゼネカ アクチボラグ キナゾリン誘導体
WO2007113565A1 (en) 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives as anti-cancer agents
WO2007113548A1 (en) 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives
FR2933700B1 (fr) 2008-07-08 2010-07-30 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
BRPI1008308B8 (pt) * 2009-02-27 2021-05-25 Teijin Pharma Ltd processo para produzir um composto
MX2012001974A (es) 2009-08-19 2012-04-11 Ambit Biosciences Corp Compuestos de biarilo y metodos de uso de los mismos.
DK2470173T3 (en) 2009-08-25 2016-06-06 Abraxis Bioscience Llc Combination therapy of nanoparticle composition of the taxane and the hedgehog inhibitors
CN102946881A (zh) 2010-04-23 2013-02-27 奇尼塔公司 抗病毒化合物
EP2651930B1 (en) 2010-12-16 2015-10-28 Boehringer Ingelheim International GmbH Biarylamide inhibitors of leukotriene production
US9212209B2 (en) 2012-07-13 2015-12-15 Indiana University Research And Technology Corporation Screening methods for spinal muscular atrophy
PT2970191T (pt) 2013-03-15 2017-03-23 Glaxosmithkline Ip Dev Ltd Derivados de piridina como inibidores da quinase rearranjada durante transfecção(ret)
KR20160055170A (ko) 2013-08-30 2016-05-17 암비트 바이오사이언시즈 코포레이션 바이아릴 아세트아미드 화합물 및 이의 사용 방법
GB201321146D0 (en) 2013-11-29 2014-01-15 Cancer Rec Tech Ltd Quinazoline compounds
US9783522B2 (en) * 2014-04-24 2017-10-10 Mitsubishi Tanabe Pharma Corporation 2-amino-pyridine and 2-amino-pyrimidine derivatives and medicinal use thereof
JP6538154B2 (ja) * 2014-09-10 2019-07-03 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Ret(rearranged during transfection)キナーゼ阻害剤としてのピリジン誘導体
JP6538153B2 (ja) * 2014-09-10 2019-07-03 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Rearranged during transfection(ret)阻害剤としての新規な化合物
JP6899323B2 (ja) 2014-10-14 2021-07-07 ラ ホーヤ インスティテュート オブ アレルギー アンド イミュノロジー 低分子量タンパク質チロシンホスファターゼの阻害剤、及びその使用
CN104844589B (zh) 2014-12-26 2018-04-20 中国科学院合肥物质科学研究院 一种pi3k激酶抑制剂
WO2016127074A1 (en) * 2015-02-06 2016-08-11 Blueprint Medicines Corporation 2-(pyridin-3-yl)-pyrimidine derivatives as ret inhibitors
SI3322706T1 (sl) 2015-07-16 2021-04-30 Array Biopharma, Inc. Substituirane pirazolo(1,5-A)piridinske spojine kot zaviralci ret-kinaze
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物

Also Published As

Publication number Publication date
EP3519398A1 (en) 2019-08-07
EA201990833A1 (ru) 2019-10-31
ZA201902232B (en) 2022-12-21
MA46337B1 (fr) 2021-04-30
IL265630B (en) 2021-10-31
US20210163464A1 (en) 2021-06-03
CY1123988T1 (el) 2022-05-27
HUE054824T2 (hu) 2021-10-28
US20200039974A1 (en) 2020-02-06
CN110036007A (zh) 2019-07-19
RS61640B1 (sr) 2021-04-29
UA123964C2 (uk) 2021-06-30
JP2018052878A (ja) 2018-04-05
MA54910A (fr) 2022-04-13
JP2019534871A (ja) 2019-12-05
HRP20210447T1 (hr) 2021-07-23
PL3519398T3 (pl) 2021-06-28
MA46337A (fr) 2019-08-07
US10851092B2 (en) 2020-12-01
CO2019004034A2 (es) 2019-07-10
EP3828178A1 (en) 2021-06-02
KR20190086442A (ko) 2019-07-22
MX2019003747A (es) 2019-09-19
ES2868748T3 (es) 2021-10-21
BR112019006047A2 (pt) 2019-06-25
LT3519398T (lt) 2021-05-10
PT3519398T (pt) 2021-03-24
AU2017335242C1 (en) 2021-12-09
AU2021261899A1 (en) 2021-12-02
ECSP19030134A (es) 2019-08-30
AU2017335242B2 (en) 2021-08-19
KR102520543B1 (ko) 2023-04-10
CA3035860A1 (en) 2018-04-05
PH12019500480A1 (en) 2019-08-05
SI3519398T1 (sl) 2021-07-30
IL265630A (en) 2019-05-30
CN110036007B (zh) 2021-10-15
EA037103B1 (ru) 2021-02-05
AU2017335242A1 (en) 2019-05-02
CL2019000844A1 (es) 2019-06-07
JP7098609B2 (ja) 2022-07-11
CN113788824A (zh) 2021-12-14
WO2018060714A1 (en) 2018-04-05
MD3519398T2 (ro) 2021-05-31
PE20190805A1 (es) 2019-06-10
DK3519398T3 (da) 2021-03-29
EP3519398B1 (en) 2021-02-24

Similar Documents

Publication Publication Date Title
SG11201901937WA (en) Pyridine compound
SG11201907451XA (en) Substituted imidazo-quinolines as nlrp3 modulators
SG11201808878UA (en) Heterocyclic compounds as ret kinase inhibitors
SG11201806863WA (en) Tetracyclic pyridone compounds as antivirals
SG11201908532UA (en) Macrocyclic compounds as ros1 kinase inhibitors
SG11201900077QA (en) 1,3-dihydroxy-phenyl derivatives useful as immunomodulators
SG11201804098TA (en) Purinones as ubiquitin-specific protease 1 inhibitors
SG11201903487SA (en) PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF
SG11201906436VA (en) Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
SG11201900163PA (en) Macrocycle kinase inhibitors
SG11201805044WA (en) Compounds useful as kinase inhibitors
SG11201403402VA (en) Compounds
SG11201500005SA (en) Pyrimidine pyrazolyl derivatives
SG11201804901WA (en) Compounds for the treatment of cancer and inflammatory disease
CA2859619C (en) Bromodomain inhibitors
SG11201805595TA (en) Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]-3-oxo-5,6,8,8a-tetrahydro-1h-imidazo[1,5-a]pyrazin-2-yl]-carboxylic acid
SG11201804263PA (en) Cancer treatment using 2-deoxy-2-fluoro-l-fucose in combination with a checkpoint inhibitor
SG11201810177VA (en) Pet-imaging immunomodulators
SG11201808237UA (en) Substituted indole compound derivatives as dengue viral replication inhibitors
SG11201811712QA (en) 5,7-dihydro-pyrrolo-pyridine derivatives for treating neurological and neurodegenerative diseases
SG11201808676RA (en) Methods of treating pediatric cancers
SG11201808222RA (en) Methods of treatment of cholestatic diseases
SG11201808106YA (en) Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
SG11201810940XA (en) Methods of treating pancreatic cancer
SG11201901389XA (en) Combination therapy with glutaminase inhibitors