SG11201610217YA - 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same - Google Patents

2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same

Info

Publication number
SG11201610217YA
SG11201610217YA SG11201610217YA SG11201610217YA SG11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA
Authority
SG
Singapore
Prior art keywords
pyridinyl
derivative compound
containing same
medicine containing
benzimidazole derivative
Prior art date
Application number
SG11201610217YA
Other languages
English (en)
Inventor
Akihiro Izawa
Kei Akama
Yuki Okumura
Yurie FUKUI
Nobuya KOBASHI
Tsutomu Abe
Yoshihiro Doi
Miho IKENAGA
Hideo Saji
Hiroyuki Kimura
Mitsuhide Naruse
Original Assignee
Nihon Mediphysics Co Ltd
Univ Kyoto
Nat Hospital Organization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd, Univ Kyoto, Nat Hospital Organization filed Critical Nihon Mediphysics Co Ltd
Publication of SG11201610217YA publication Critical patent/SG11201610217YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201610217YA 2014-06-26 2015-06-25 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same SG11201610217YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014131934 2014-06-26
PCT/JP2015/068431 WO2015199205A1 (ja) 2014-06-26 2015-06-25 ２－（３－ピリジニル）－１ｈ－ベンゾイミダゾール誘導体化合物、及び、これを含む医薬

Publications (1)

Publication Number Publication Date
SG11201610217YA true SG11201610217YA (en) 2017-01-27

Family

ID=54938282

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201610217YA SG11201610217YA (en) 2014-06-26 2015-06-25 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same

Country Status (11)

Country Link
US (2) US10189815B2 (zh)
EP (1) EP3162802B1 (zh)
JP (1) JP6636921B2 (zh)
KR (1) KR20170017871A (zh)
CN (1) CN106458995B (zh)
AU (1) AU2015281060B2 (zh)
CA (1) CA2953692A1 (zh)
ES (1) ES2821273T3 (zh)
MX (1) MX2016017405A (zh)
SG (1) SG11201610217YA (zh)
WO (1) WO2015199205A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190016971A (ko) * 2016-06-10 2019-02-19 니혼 메디피직스 가부시키가이샤 심질환의 비침습적 화상 진단제
US20200009273A1 (en) * 2017-03-07 2020-01-09 Nihon Medi-Physics Co., Ltd. Radioactive fluorine-labeled precursor compound, and method for producing radioactive fluorine-labeled compound using same
CN110809575A (zh) 2017-06-23 2020-02-18 日本医事物理股份有限公司 放射性卤素标记化合物的制造方法及放射性医药的制造方法
JP7054134B2 (ja) * 2017-12-07 2022-04-13 国立大学法人京都大学 ベンゾ［ｂ］カルバゾール化合物及びそれを用いたイメージング
WO2019131458A1 (ja) 2017-12-28 2019-07-04 日本メジフィジックス株式会社 ２－［５－（イミダゾール－１－イルメチル）ピリジン－３－イル］ベンズイミダゾール誘導体化合物、及び、これを含む医薬
JP2021130610A (ja) * 2018-05-08 2021-09-09 日本メジフィジックス株式会社 心疾患の非侵襲的画像診断剤
JP2021181404A (ja) * 2018-08-23 2021-11-25 日本メジフィジックス株式会社 放射性フッ素標識化合物の標識前駆体化合物を含有する溶液
WO2020085238A1 (ja) * 2018-10-24 2020-04-30 日本メジフィジックス株式会社 放射性フッ素標識前駆体化合物の塩

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071785B2 (en) 2006-06-09 2011-12-06 Ge Healthcare Limited Synthesis and evaluation of 18F-labelled-alkyl-1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate as a tracer for the quantification of β-11-hydroxylase enzyme in the adrenal glands
EP2394668A1 (en) 2010-06-01 2011-12-14 Julius-Maximilians-Universität Würzburg PET radiopharmaceuticals for differential diagnosis between bilateral and unilateral conditions of primary hyperaldosteronism
US9382226B2 (en) 2010-07-21 2016-07-05 Merck Sharp & Dohme Corp. Aldosterone synthase inhibitors
JP2015110563A (ja) * 2013-11-08 2015-06-18 日本メジフィジックス株式会社 アルドステロン合成酵素阻害剤

Also Published As

Publication number Publication date
AU2015281060B2 (en) 2019-03-14
KR20170017871A (ko) 2017-02-15
US20170158668A1 (en) 2017-06-08
CN106458995A (zh) 2017-02-22
JP6636921B2 (ja) 2020-01-29
EP3162802B1 (en) 2020-08-19
EP3162802A4 (en) 2018-01-17
MX2016017405A (es) 2017-08-24
AU2015281060A1 (en) 2017-01-05
JPWO2015199205A1 (ja) 2017-04-20
US10358434B2 (en) 2019-07-23
EP3162802A1 (en) 2017-05-03
WO2015199205A1 (ja) 2015-12-30
US10189815B2 (en) 2019-01-29
ES2821273T3 (es) 2021-04-23
US20190169169A1 (en) 2019-06-06
CN106458995B (zh) 2019-12-20
CA2953692A1 (en) 2015-12-30

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