SG11201610217YA - 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same - Google Patents

2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same

Info

Publication number
SG11201610217YA
SG11201610217YA SG11201610217YA SG11201610217YA SG11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA SG 11201610217Y A SG11201610217Y A SG 11201610217YA
Authority
SG
Singapore
Prior art keywords
pyridinyl
derivative compound
containing same
medicine containing
benzimidazole derivative
Prior art date
Application number
SG11201610217YA
Inventor
Akihiro Izawa
Kei Akama
Yuki Okumura
Yurie FUKUI
Nobuya KOBASHI
Tsutomu Abe
Yoshihiro Doi
Miho IKENAGA
Hideo Saji
Hiroyuki Kimura
Mitsuhide Naruse
Original Assignee
Nihon Mediphysics Co Ltd
Univ Kyoto
Nat Hospital Organization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd, Univ Kyoto, Nat Hospital Organization filed Critical Nihon Mediphysics Co Ltd
Publication of SG11201610217YA publication Critical patent/SG11201610217YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201610217YA 2014-06-26 2015-06-25 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same SG11201610217YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014131934 2014-06-26
PCT/JP2015/068431 WO2015199205A1 (en) 2014-06-26 2015-06-25 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same

Publications (1)

Publication Number Publication Date
SG11201610217YA true SG11201610217YA (en) 2017-01-27

Family

ID=54938282

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201610217YA SG11201610217YA (en) 2014-06-26 2015-06-25 2-(3-pyridinyl)-1h-benzimidazole derivative compound and medicine containing same

Country Status (11)

Country Link
US (2) US10189815B2 (en)
EP (1) EP3162802B1 (en)
JP (1) JP6636921B2 (en)
KR (1) KR20170017871A (en)
CN (1) CN106458995B (en)
AU (1) AU2015281060B2 (en)
CA (1) CA2953692A1 (en)
ES (1) ES2821273T3 (en)
MX (1) MX2016017405A (en)
SG (1) SG11201610217YA (en)
WO (1) WO2015199205A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017278446A1 (en) * 2016-06-10 2018-12-20 Nihon Medi-Physics Co., Ltd. Non-invasive diagnostic imaging agent for heart disease
ES2909126T3 (en) 2017-03-07 2022-05-05 Nihon Mediphysics Co Ltd Radioactive fluorine labeled precursor compound and method for producing a radioactive fluorine labeled compound using the same
WO2018235535A1 (en) 2017-06-23 2018-12-27 日本メジフィジックス株式会社 Production method for radiohalogen-labeled compound and production method for raidopharmaceutical
JP7054134B2 (en) * 2017-12-07 2022-04-13 国立大学法人京都大学 Benzo [b] carbazole compound and imaging using it
US11266753B2 (en) 2017-12-28 2022-03-08 Nihon Medi-Physics Co., Ltd. 2-[5-(imidazol-1-ylmethyl)pyridin-3-yl]benzimtdazole derivative compound, and medicament including same
JP2021130610A (en) * 2018-05-08 2021-09-09 日本メジフィジックス株式会社 Non-invasive diagnostic imaging agent for heart disease
JP2021181404A (en) * 2018-08-23 2021-11-25 日本メジフィジックス株式会社 Solution containing labeled precursor compound of radioactive fluorine-labeled compound
WO2020085238A1 (en) * 2018-10-24 2020-04-30 日本メジフィジックス株式会社 Salt of radioactive fluorine-labeled precursor compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007144725A2 (en) 2006-06-09 2007-12-21 Ge Healthcare Limited SYNTHESIS AND EVALUATION OF 18F-LABELLED ALKYL-1-[(R)-1-PHENYLETHYL]-1H-IMIDAZOLE-5-CARBOXYLATE AS A TRACER FOR THE QUANTIFICATION OF β-11-HYDROXYLASE ENZYME IN THE ADRENAL GLANDS
EP2394668A1 (en) 2010-06-01 2011-12-14 Julius-Maximilians-Universität Würzburg PET radiopharmaceuticals for differential diagnosis between bilateral and unilateral conditions of primary hyperaldosteronism
EP2595482A4 (en) 2010-07-21 2013-12-25 Merck Sharp & Dohme Aldosterone synthase inhibitors
JP2015110563A (en) * 2013-11-08 2015-06-18 日本メジフィジックス株式会社 Aldosterone synthase inhibitor

Also Published As

Publication number Publication date
US20190169169A1 (en) 2019-06-06
US10358434B2 (en) 2019-07-23
ES2821273T3 (en) 2021-04-23
CN106458995B (en) 2019-12-20
US20170158668A1 (en) 2017-06-08
EP3162802B1 (en) 2020-08-19
AU2015281060B2 (en) 2019-03-14
JPWO2015199205A1 (en) 2017-04-20
WO2015199205A1 (en) 2015-12-30
EP3162802A4 (en) 2018-01-17
CN106458995A (en) 2017-02-22
JP6636921B2 (en) 2020-01-29
CA2953692A1 (en) 2015-12-30
MX2016017405A (en) 2017-08-24
AU2015281060A1 (en) 2017-01-05
KR20170017871A (en) 2017-02-15
US10189815B2 (en) 2019-01-29
EP3162802A1 (en) 2017-05-03

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