SG11201605595YA - Fusion of heterooligomeric mycobacterial antigens - Google Patents
Fusion of heterooligomeric mycobacterial antigensInfo
- Publication number
- SG11201605595YA SG11201605595YA SG11201605595YA SG11201605595YA SG11201605595YA SG 11201605595Y A SG11201605595Y A SG 11201605595YA SG 11201605595Y A SG11201605595Y A SG 11201605595YA SG 11201605595Y A SG11201605595Y A SG 11201605595YA SG 11201605595Y A SG11201605595Y A SG 11201605595YA
- Authority
- SG
- Singapore
- Prior art keywords
- fusion
- mycobacterial antigens
- heterooligomeric
- heterooligomeric mycobacterial
- antigens
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14305030 | 2014-01-09 | ||
PCT/EP2015/050344 WO2015104380A1 (en) | 2014-01-09 | 2015-01-09 | Fusion of heterooligomeric mycobacterial antigens |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201605595YA true SG11201605595YA (en) | 2016-08-30 |
Family
ID=49989636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201605595YA SG11201605595YA (en) | 2014-01-09 | 2015-01-09 | Fusion of heterooligomeric mycobacterial antigens |
Country Status (12)
Country | Link |
---|---|
US (1) | US10765731B2 (zh) |
EP (1) | EP3092000A1 (zh) |
JP (1) | JP6605480B2 (zh) |
KR (1) | KR20160130216A (zh) |
CN (1) | CN106103471B (zh) |
BR (1) | BR112016015936A2 (zh) |
CA (1) | CA2936131A1 (zh) |
IL (1) | IL246659A0 (zh) |
MX (1) | MX2016009072A (zh) |
RU (1) | RU2695462C2 (zh) |
SG (1) | SG11201605595YA (zh) |
WO (1) | WO2015104380A1 (zh) |
Families Citing this family (18)
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MY173004A (en) * | 2012-07-10 | 2019-12-18 | Transgene Sa | Mycobacterial antigen vaccine |
WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
CN105218680B (zh) * | 2015-10-21 | 2019-06-25 | 中山大学 | 一种用于诱导外周血单个核细胞产生细胞因子的结核分支杆菌融合蛋白 |
CN105601747B (zh) * | 2015-10-21 | 2019-05-28 | 中山大学 | 一种结核杆菌融合蛋白及其在诱导外周血单个核细胞产生细胞因子的应用 |
EP3452081A1 (en) | 2016-05-04 | 2019-03-13 | Transgene SA | Combination therapy with cpg tlr9 ligand |
MX2018014270A (es) * | 2016-05-21 | 2019-02-14 | Infectious Disease Res Inst | Composiciones y metodos para tratar la tuberculosis secundaria e infecciones po micobacteria no tuberculosa. |
EP3474889A4 (en) | 2016-06-22 | 2020-04-29 | International AIDS Vaccine Initiative, Inc. | RECOMBINANT CYTOMEGALOVIRUS VECTORS AS VACCINE AGAINST TUBERCULOSIS |
EP3522920A2 (en) | 2016-10-10 | 2019-08-14 | Transgene SA | Immunotherapeutic product and mdsc modulator combination therapy |
EP3697806A4 (en) | 2017-10-17 | 2021-10-27 | International AIDS Vaccine Initiative, Inc. | TUBERCULOSIS ANTIGEN CASSETTES |
KR102004902B1 (ko) * | 2017-12-26 | 2019-07-29 | 연세대학교 산학협력단 | 융합 단백질을 포함하는 결핵 예방용 조성물 |
CN110684116B (zh) * | 2019-08-23 | 2022-04-26 | 成都可恩生物科技有限公司 | 一种结核分枝杆菌eec融合蛋白、制备方法及其应用 |
CN110590957B (zh) * | 2019-09-11 | 2021-06-01 | 中国人民解放军总医院第八医学中心 | 一种融合蛋白及其在抗结核分枝杆菌的免疫保护中的应用 |
RU2724896C1 (ru) * | 2019-11-14 | 2020-06-26 | федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации | Полиантигенная вакцина для профилактики и вспомогательного лечения туберкулеза |
CN111269297B (zh) * | 2020-01-23 | 2021-11-30 | 郑州伊美诺生物技术有限公司 | 一种结核分枝杆菌刺激抗原的制备方法 |
WO2024028445A1 (en) * | 2022-08-03 | 2024-02-08 | BioNTech SE | Rna for preventing or treating tuberculosis |
WO2024027910A1 (en) * | 2022-08-03 | 2024-02-08 | BioNTech SE | Rna for preventing or treating tuberculosis |
CN116162141B (zh) * | 2022-11-30 | 2024-04-12 | 中国疾病预防控制中心传染病预防控制所 | 一种结核分枝杆菌抗原epcra013及其应用 |
CN116063418B (zh) * | 2022-12-08 | 2024-04-12 | 中国疾病预防控制中心传染病预防控制所 | 结核分枝杆菌抗原组合物epdpa015及其制备方法与应用 |
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MY173004A (en) | 2012-07-10 | 2019-12-18 | Transgene Sa | Mycobacterial antigen vaccine |
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CN103204945A (zh) | 2013-05-03 | 2013-07-17 | 扬州大学 | 一种用于牛结核病诊断的真核表达cfp10-esat-6融合蛋白 |
WO2014210018A1 (en) | 2013-06-25 | 2014-12-31 | Aeras Global Tb Vaccine Foundation | Tuberculosis compositions and methods of using the same |
CN103386128B (zh) | 2013-07-02 | 2017-02-08 | 中国食品药品检定研究院 | 一种含联合佐剂的结核亚单位疫苗 |
-
2015
- 2015-01-09 SG SG11201605595YA patent/SG11201605595YA/en unknown
- 2015-01-09 RU RU2016131853A patent/RU2695462C2/ru not_active IP Right Cessation
- 2015-01-09 MX MX2016009072A patent/MX2016009072A/es unknown
- 2015-01-09 US US15/110,514 patent/US10765731B2/en active Active
- 2015-01-09 JP JP2016545896A patent/JP6605480B2/ja not_active Expired - Fee Related
- 2015-01-09 CA CA2936131A patent/CA2936131A1/en not_active Abandoned
- 2015-01-09 CN CN201580012192.0A patent/CN106103471B/zh not_active Expired - Fee Related
- 2015-01-09 BR BR112016015936A patent/BR112016015936A2/pt not_active Application Discontinuation
- 2015-01-09 EP EP15700284.1A patent/EP3092000A1/en not_active Withdrawn
- 2015-01-09 KR KR1020167020984A patent/KR20160130216A/ko not_active Application Discontinuation
- 2015-01-09 WO PCT/EP2015/050344 patent/WO2015104380A1/en active Application Filing
-
2016
- 2016-07-07 IL IL246659A patent/IL246659A0/en unknown
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MX2016009072A (es) | 2017-05-08 |
CN106103471B (zh) | 2020-01-07 |
RU2016131853A (ru) | 2018-02-12 |
EP3092000A1 (en) | 2016-11-16 |
US20160331823A1 (en) | 2016-11-17 |
IL246659A0 (en) | 2016-08-31 |
KR20160130216A (ko) | 2016-11-10 |
CA2936131A1 (en) | 2015-07-16 |
BR112016015936A2 (pt) | 2017-09-19 |
JP6605480B2 (ja) | 2019-11-13 |
US10765731B2 (en) | 2020-09-08 |
JP2017505605A (ja) | 2017-02-23 |
CN106103471A (zh) | 2016-11-09 |
WO2015104380A1 (en) | 2015-07-16 |
RU2695462C2 (ru) | 2019-07-23 |
RU2016131853A3 (zh) | 2018-06-26 |
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