SG11201508186XA - Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids - Google Patents
Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoidsInfo
- Publication number
- SG11201508186XA SG11201508186XA SG11201508186XA SG11201508186XA SG11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA
- Authority
- SG
- Singapore
- Prior art keywords
- phosphoketolases
- isoprenoids
- isoprene
- improved production
- acetyl coenzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/02—Aldehyde-lyases (4.1.2)
- C12Y401/02009—Phosphoketolase (4.1.2.9)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361810696P | 2013-04-10 | 2013-04-10 | |
| US201361834359P | 2013-06-12 | 2013-06-12 | |
| PCT/US2014/033688 WO2014169144A2 (fr) | 2013-04-10 | 2014-04-10 | Phosphocétolases pour une production améliorée de métabolites dérivés de l'acétyl co-enzyme a, isoprène, précurseurs d'isoprénoïdes et isoprénoïdes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201508186XA true SG11201508186XA (en) | 2015-11-27 |
Family
ID=50877659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201508186XA SG11201508186XA (en) | 2013-04-10 | 2014-04-10 | Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10246694B2 (fr) |
| EP (2) | EP2984105B1 (fr) |
| JP (2) | JP6530375B2 (fr) |
| CN (1) | CN105555952A (fr) |
| BR (1) | BR112015025489A2 (fr) |
| ES (1) | ES2735331T3 (fr) |
| SG (1) | SG11201508186XA (fr) |
| WO (1) | WO2014169144A2 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| EP2984105B1 (fr) | 2013-04-10 | 2019-05-22 | Danisco US Inc. | Phosphocétolases pour une production améliorée de métabolites dérivés de l'acétyl co-enzyme a, isoprène, précurseurs d'isoprénoïdes et isoprénoïdes |
| EP3194604B1 (fr) * | 2014-09-18 | 2020-02-26 | Genomatica, Inc. | Organismes microbiens non naturels présentant une meilleure efficacité énergétique |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| BR112019019701A2 (pt) * | 2017-03-24 | 2020-07-14 | Danisco Us Inc. | redução de acetato e glicerol em levedura modificada que tem um caminho de produção de etanol exógeno |
| CN107841523A (zh) * | 2017-10-19 | 2018-03-27 | 浙江大学 | 利用群体感应分子诱导从桦褐孔菌中提取三萜类物质方法 |
| KR20200095534A (ko) | 2017-12-07 | 2020-08-10 | 지머젠 인코포레이티드 | 발효에 의한 (6e)-8-히드록시제라니올의 제조를 위해 조작된 생합성 경로 |
| CA3086490A1 (fr) | 2017-12-21 | 2019-06-27 | Zymergen Inc. | Nepetalactol oxydoreductases, nepetalactol synthases et microbes capables de produire une nepetalactone |
| US11634701B2 (en) | 2018-03-01 | 2023-04-25 | Total Raffinage Chimie | Metabolic pathways with increased carbon yield |
| CN109929883A (zh) * | 2019-04-02 | 2019-06-25 | 烟台华康荣赞生物科技有限公司 | 重组酵母、构建方法和其在制备酪醇及衍生物中的应用 |
| WO2021063958A1 (fr) * | 2019-09-30 | 2021-04-08 | Global Bioenergies | Moyens et procédés améliorés pour augmenter le rendement d'acétyl-coa à partir du glucose |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR669447A (fr) | 1929-02-09 | 1929-11-15 | Dispositif pour arrêter automatiquement un moteur d'automobile après une période de temps prédéterminée | |
| DE19629568C1 (de) | 1996-07-15 | 1998-01-08 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von Isopren |
| US7172886B2 (en) | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| AU2003234790A1 (en) | 2002-05-10 | 2003-11-11 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing mevalonic acid |
| US7371558B2 (en) | 2002-10-04 | 2008-05-13 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
| EP1789547B1 (fr) * | 2004-08-10 | 2010-04-07 | Ajinomoto Co., Inc. | Utilisation de phosphocetolase pour produire des metabolites utiles |
| RU2004124226A (ru) * | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
| US7659097B2 (en) | 2006-05-26 | 2010-02-09 | Amyris Biotechnologies, Inc. | Production of isoprenoids |
| JP4986547B2 (ja) | 2006-09-04 | 2012-07-25 | 株式会社Ａｄｅｋａ | 新規なアセトアセチルＣｏＡ合成酵素、それをコードするＤＮＡ配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法 |
| WO2009005704A1 (fr) * | 2007-07-03 | 2009-01-08 | The Regents Of The University Of California | Procédés d'augmentation de la production d'isoprénoïde ou de précurseur d'isoprénoïde |
| MX2010006576A (es) | 2007-12-13 | 2010-10-15 | Danisco Us Inc | Composiciones y metodos para producir isopreno. |
| WO2009100231A2 (fr) | 2008-02-06 | 2009-08-13 | The Regents Of The University Of California | Production d'hydrocarbures d'isoprène volatil à chaîne courte en utilisant la voie de l'acide mévalonique dans des levures et des champignons génétiquement modifiés |
| MX2010011706A (es) | 2008-04-23 | 2011-03-15 | Danisco Us Inc | Variantes de isopreno-sintasa para produccion microbiana mejorada de isopreno. |
| US7632995B2 (en) | 2008-05-09 | 2009-12-15 | Monsanto Technology Llc | Plants and seeds of hybrid corn variety CH852179 |
| MY156256A (en) | 2008-07-02 | 2016-01-29 | Danisco Us Inc | Compositions and methods for producing isoprene free of c5 hydrocarbons under decoupling conditions and/or safe operating ranges |
| HU3516U (en) | 2008-07-31 | 2008-11-28 | Zoltan Kuthi | Anti-theft protection of draining for fuel tanks |
| ZA201102111B (en) | 2008-09-15 | 2013-10-30 | Danisco Us Inc | Reduction of carbon dioxide emission during isoprene production by fermentation |
| MY169163A (en) | 2008-09-15 | 2019-02-19 | Danisco Us Inc | Increased isoprene production using the archaeal lower mevalonate pathway |
| US20100184178A1 (en) | 2008-09-15 | 2010-07-22 | Zachary Quinn Beck | Increased isoprene production using mevalonate kinase and isoprene synthase |
| WO2010031076A2 (fr) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Conversion de dérivés de prényle en isoprène |
| BRPI0918453A2 (pt) | 2008-09-15 | 2019-12-17 | Danisco Us Inc | sistemas usando cultura de células para a produção de isopreno |
| MY161071A (en) | 2008-12-30 | 2017-04-14 | Danisco Us Inc | Methods of producing isoprene and a co-product |
| US8324442B2 (en) | 2009-03-03 | 2012-12-04 | Amyris, Inc. | Microbial derived isoprene and methods for making the same |
| US20100297749A1 (en) | 2009-04-21 | 2010-11-25 | Sapphire Energy, Inc. | Methods and systems for biofuel production |
| EP2421966A2 (fr) | 2009-04-23 | 2012-02-29 | Danisco US Inc. | Structure tridimensionnelle de l'isoprène synthase et son utilisation dans la production de variants |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| TWI427149B (zh) | 2009-06-17 | 2014-02-21 | Danisco Us Inc | 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造 |
| TWI434921B (zh) | 2009-06-17 | 2014-04-21 | Danisco Us Inc | 從生物異戊二烯組合物製造燃料成分之方法及系統 |
| WO2011034863A1 (fr) | 2009-09-15 | 2011-03-24 | Sapphire Energy, Inc. | Système de transformation du génome chloroplastique des espèces scenedesmus et dunaliella |
| BR112012014736B1 (pt) | 2009-12-18 | 2018-09-18 | Danisco Us Inc | método para purificação de isopreno a partir de um efluente gasoso do fermentador e composição |
| WO2011079314A2 (fr) | 2009-12-23 | 2011-06-30 | Danisco Us Inc. | Compositions et procédés de pgl pour la production augmentée d'isoprène |
| US8871488B2 (en) * | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| JP2014502148A (ja) | 2010-10-27 | 2014-01-30 | ダニスコ・ユーエス・インク | イソプレン生産の向上を目的としたイソプレン合成酵素変異体 |
| EP2702139A1 (fr) * | 2011-04-29 | 2014-03-05 | Danisco US Inc. | Production de mévalonate, d'isoprène et d'isoprénoïdes au moyen de gènes codant des polypeptides à activité enzymatique thiolase, hmg-coa synthase et hmg-coa réductase |
| ES2699747T3 (es) * | 2011-04-29 | 2019-02-12 | Danisco Us Inc | Microorganismos recombinantes para la producción potenciada de mevalonato, isopreno e isoprenoides |
| DK2732031T3 (en) | 2011-07-12 | 2015-11-30 | Scientist Of Fortune Sa | Recombinant microorganism to produce useful metabolic products |
| SG11201401249PA (en) * | 2011-10-07 | 2014-05-29 | Danisco Us Inc | Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene |
| MX346459B (es) | 2011-11-09 | 2017-03-22 | Amyris Inc | Produccion de isoprenoides derivados de acetil - coenzima a. |
| SG11201406923WA (en) | 2012-05-16 | 2014-12-30 | Glycos Biotechnologies Inc | Microorganisms and processes for the production of isoprene |
| EP2984105B1 (fr) | 2013-04-10 | 2019-05-22 | Danisco US Inc. | Phosphocétolases pour une production améliorée de métabolites dérivés de l'acétyl co-enzyme a, isoprène, précurseurs d'isoprénoïdes et isoprénoïdes |
-
2014
- 2014-04-10 EP EP14727659.6A patent/EP2984105B1/fr active Active
- 2014-04-10 BR BR112015025489A patent/BR112015025489A2/pt not_active Application Discontinuation
- 2014-04-10 SG SG11201508186XA patent/SG11201508186XA/en unknown
- 2014-04-10 US US14/783,391 patent/US10246694B2/en active Active
- 2014-04-10 CN CN201480032280.2A patent/CN105555952A/zh active Pending
- 2014-04-10 EP EP18175724.6A patent/EP3425049A1/fr not_active Withdrawn
- 2014-04-10 ES ES14727659T patent/ES2735331T3/es active Active
- 2014-04-10 WO PCT/US2014/033688 patent/WO2014169144A2/fr active Application Filing
- 2014-04-10 JP JP2016507665A patent/JP6530375B2/ja active Active
-
2019
- 2019-02-14 US US16/276,558 patent/US10988750B2/en active Active
- 2019-05-16 JP JP2019093057A patent/JP2019162130A/ja active Pending
-
2020
- 2020-09-24 US US16/948,592 patent/US11371035B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10246694B2 (en) | 2019-04-02 |
| ES2735331T3 (es) | 2019-12-18 |
| BR112015025489A2 (pt) | 2017-10-10 |
| CN105555952A (zh) | 2016-05-04 |
| US20160068831A1 (en) | 2016-03-10 |
| US10988750B2 (en) | 2021-04-27 |
| US20190367896A1 (en) | 2019-12-05 |
| US11371035B2 (en) | 2022-06-28 |
| WO2014169144A8 (fr) | 2015-10-15 |
| JP2019162130A (ja) | 2019-09-26 |
| WO2014169144A3 (fr) | 2014-12-04 |
| JP6530375B2 (ja) | 2019-06-12 |
| JP2016519577A (ja) | 2016-07-07 |
| EP2984105B1 (fr) | 2019-05-22 |
| EP3425049A1 (fr) | 2019-01-09 |
| WO2014169144A2 (fr) | 2014-10-16 |
| US20210139878A1 (en) | 2021-05-13 |
| EP2984105A2 (fr) | 2016-02-17 |
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