SG11201505388QA - Method of producing a protein - Google Patents

Method of producing a protein

Info

Publication number
SG11201505388QA
SG11201505388QA SG11201505388QA SG11201505388QA SG11201505388QA SG 11201505388Q A SG11201505388Q A SG 11201505388QA SG 11201505388Q A SG11201505388Q A SG 11201505388QA SG 11201505388Q A SG11201505388Q A SG 11201505388QA SG 11201505388Q A SG11201505388Q A SG 11201505388QA
Authority
SG
Singapore
Prior art keywords
protein
producing
Prior art date
Application number
SG11201505388QA
Other languages
English (en)
Inventor
Alex Chatel
Michael Hoare
Peter Kumpalume
Jessica Rachel Molek
Jason Michael Reck
Andrew David Weber
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SG11201505388QA publication Critical patent/SG11201505388QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/303—Extraction; Separation; Purification by precipitation by salting out
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/32—Extraction; Separation; Purification by precipitation as complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201505388QA 2013-01-31 2014-01-29 Method of producing a protein SG11201505388QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361758870P 2013-01-31 2013-01-31
US201361899437P 2013-11-04 2013-11-04
PCT/EP2014/051705 WO2014118220A1 (en) 2013-01-31 2014-01-29 Method of producing a protein

Publications (1)

Publication Number Publication Date
SG11201505388QA true SG11201505388QA (en) 2015-08-28

Family

ID=50033522

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505388QA SG11201505388QA (en) 2013-01-31 2014-01-29 Method of producing a protein

Country Status (13)

Country Link
US (1) US20150368292A1 (zh)
EP (1) EP2951192A1 (zh)
JP (1) JP2016504918A (zh)
KR (1) KR20150113105A (zh)
CN (1) CN104936973A (zh)
AU (1) AU2014211438B2 (zh)
BR (1) BR112015017994A2 (zh)
CA (1) CA2897345A1 (zh)
IL (1) IL239737A0 (zh)
RU (1) RU2015128651A (zh)
SG (1) SG11201505388QA (zh)
TW (1) TW201514193A (zh)
WO (1) WO2014118220A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6811725B2 (ja) 2015-05-15 2021-01-13 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 組換えタンパク質の生成方法
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
CN105462943A (zh) * 2015-12-30 2016-04-06 海口奇力制药股份有限公司 无机氯化物的应用、杂蛋白絮凝组合物及杂蛋白絮凝方法
AU2017310785B9 (en) * 2016-08-10 2022-07-21 Spiber Inc. Production method for insoluble recombinant protein aggregate
MA49288A (fr) 2017-04-27 2020-03-04 Juno Therapeutics Gmbh Reactifs particulaires oligomères et leurs méthodes d'utilisation
WO2020044201A1 (en) * 2018-08-30 2020-03-05 Glaxosmithkline Intellectual Property Development Limited Methods of detecting nucleic acid
JP7239509B6 (ja) * 2019-02-22 2023-03-28 ファイザー・インク 細菌多糖類を精製するための方法
CN110577566B (zh) * 2019-08-09 2021-05-04 北京首朗生物科技有限公司 一种梭菌菌体蛋白的制备方法
BR112023005111A2 (pt) 2020-09-22 2023-04-18 Basf Se Método para recuperar uma proteína de interesse de um caldo de fermentação bacteriana, e, uso de pelo menos um floculante
CN114574457A (zh) * 2022-01-25 2022-06-03 华东理工大学 一种快速分离纯化蛋白质的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1041824C (zh) * 1991-06-18 1999-01-27 华东北工学院 从发酵液中提取ｌ－赖氨酸的方法
EA012622B1 (ru) 2004-06-01 2009-10-30 Домэнтис Лимитед Биспецифичные гибридные антитела с увеличенным периодом полувыведения из сыворотки
GB0602173D0 (en) 2006-02-03 2006-03-15 Avecia Ltd Expression system
KR20100018040A (ko) * 2007-06-06 2010-02-16 도만티스 리미티드 프로테아제 내성 폴리펩티드를 선택하는 방법
CL2008003561A1 (es) 2007-11-30 2010-02-05 Glaxo Group Ltd Construccion de union a il - 13 que comprende a lo menos un dominio simple (dab) de anticuerpo injertado en un anticuerpo monoclonal ( mabdab); polinucleotido y celula huesped; procedimiento para preparar la construccion; composicion farmaceutica que la comprende y uso para tratar cancer o enfermedades inflamatorias.
US20110184154A1 (en) * 2008-10-17 2011-07-28 Percivia Llc Cell broth clarification and host cell protein removal
CA2756853A1 (en) * 2009-03-27 2010-09-30 Christopher Herring Drug fusions and conjugates
WO2011008814A2 (en) * 2009-07-14 2011-01-20 Immune Tolerance Institute, Inc., A California Not-For-Profit Corporation Multiplexed measurement of exogenous and endogenous dna
CN101665778B (zh) * 2009-09-25 2012-03-28 浙江大学 黄色素生成缺陷鞘脂单胞菌及其在结冷胶生产中的应用
EP2483308A1 (en) * 2009-09-30 2012-08-08 Glaxo Group Limited Drug fusions and conjugates with extended half life
TW201125877A (en) * 2009-10-27 2011-08-01 Glaxo Group Ltd Stable anti-TNFR1 polypeptides, antibody variable domains & and antagonists

Also Published As

Publication number Publication date
TW201514193A (zh) 2015-04-16
AU2014211438A1 (en) 2015-08-20
WO2014118220A1 (en) 2014-08-07
US20150368292A1 (en) 2015-12-24
JP2016504918A (ja) 2016-02-18
CA2897345A1 (en) 2014-08-07
CN104936973A (zh) 2015-09-23
KR20150113105A (ko) 2015-10-07
BR112015017994A2 (pt) 2017-07-11
RU2015128651A (ru) 2017-03-06
AU2014211438B2 (en) 2017-02-02
IL239737A0 (en) 2015-08-31
EP2951192A1 (en) 2015-12-09

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