HK1208864A1 - 種海鞘碱- 中間體的製備方法 - Google Patents

種海鞘碱- 中間體的製備方法

Info

Publication number
HK1208864A1
HK1208864A1 HK15109524.9A HK15109524A HK1208864A1 HK 1208864 A1 HK1208864 A1 HK 1208864A1 HK 15109524 A HK15109524 A HK 15109524A HK 1208864 A1 HK1208864 A1 HK 1208864A1
Authority
HK
Hong Kong
Prior art keywords
ecteinascidin
preparation
Prior art date
Application number
HK15109524.9A
Other languages
English (en)
Inventor
張富堯
任國寶
胡高强
羅揚
Original Assignee
Unitris Biopharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unitris Biopharma Co Ltd filed Critical Unitris Biopharma Co Ltd
Publication of HK1208864A1 publication Critical patent/HK1208864A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK15109524.9A 2013-10-29 2015-09-29 種海鞘碱- 中間體的製備方法 HK1208864A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310526056.6A CN104557850B (zh) 2013-10-29 2013-10-29 一种海鞘碱-743中间体的制备方法

Publications (1)

Publication Number Publication Date
HK1208864A1 true HK1208864A1 (zh) 2016-03-18

Family

ID=53075023

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109524.9A HK1208864A1 (zh) 2013-10-29 2015-09-29 種海鞘碱- 中間體的製備方法

Country Status (2)

Country Link
CN (2) CN108084146B (zh)
HK (1) HK1208864A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108101881B (zh) * 2016-11-24 2021-01-19 江苏恒瑞医药股份有限公司 用于制备曲贝替定的方法及其中间体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721362A (en) * 1996-09-18 1998-02-24 President And Fellows Of Harvard College Process for producing ecteinascidin compounds

Also Published As

Publication number Publication date
CN108084146A (zh) 2018-05-29
CN104557850A (zh) 2015-04-29
CN104557850B (zh) 2019-07-30
CN108084146B (zh) 2020-07-28

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HK1208864A1 (zh) 種海鞘碱- 中間體的製備方法