HK1208864A1 - A preparation method of ecteinascidin-743 intermediate -743 - Google Patents

A preparation method of ecteinascidin-743 intermediate -743

Info

Publication number
HK1208864A1
HK1208864A1 HK15109524.9A HK15109524A HK1208864A1 HK 1208864 A1 HK1208864 A1 HK 1208864A1 HK 15109524 A HK15109524 A HK 15109524A HK 1208864 A1 HK1208864 A1 HK 1208864A1
Authority
HK
Hong Kong
Prior art keywords
ecteinascidin
preparation
Prior art date
Application number
HK15109524.9A
Other languages
Chinese (zh)
Inventor
張富堯
任國寶
胡高强
羅揚
Original Assignee
Unitris Biopharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unitris Biopharma Co Ltd filed Critical Unitris Biopharma Co Ltd
Publication of HK1208864A1 publication Critical patent/HK1208864A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
HK15109524.9A 2013-10-29 2015-09-29 A preparation method of ecteinascidin-743 intermediate -743 HK1208864A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310526056.6A CN104557850B (en) 2013-10-29 2013-10-29 A kind of preparation method of -743 intermediate of ascidian alkali

Publications (1)

Publication Number Publication Date
HK1208864A1 true HK1208864A1 (en) 2016-03-18

Family

ID=53075023

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109524.9A HK1208864A1 (en) 2013-10-29 2015-09-29 A preparation method of ecteinascidin-743 intermediate -743

Country Status (2)

Country Link
CN (2) CN108084146B (en)
HK (1) HK1208864A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108101881B (en) * 2016-11-24 2021-01-19 江苏恒瑞医药股份有限公司 Process for the preparation of trabectedin and intermediates thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721362A (en) * 1996-09-18 1998-02-24 President And Fellows Of Harvard College Process for producing ecteinascidin compounds

Also Published As

Publication number Publication date
CN108084146A (en) 2018-05-29
CN104557850A (en) 2015-04-29
CN104557850B (en) 2019-07-30
CN108084146B (en) 2020-07-28

Similar Documents

Publication Publication Date Title
GB201313840D0 (en) Method of Manufacturing a Component
GB201313841D0 (en) Method of Manufacturing a Component
GB201313839D0 (en) Method of Manufacturing a Component
GB201401248D0 (en) Method of manufacture
GB2525345C (en) A method of plugging a well
GB2526010B (en) A method of plugging a well
IL239737A0 (en) Method of producing a protein
EP2986385A4 (en) Method of making a droplet-generating device
LT3003866T (en) Method of manufacture of a dispenser
HK1214240A1 (en) Method for preparation of imidodisulfuryl compounds
EP2960338A4 (en) Sugar-solution production method
EP3023416A4 (en) Preparation of (-)-huperzine a
ZA201506677B (en) Firelog and method of making a firelog
GB201301857D0 (en) Method
GB201305231D0 (en) Method of Manufacture
GB201301233D0 (en) Method
GB201300409D0 (en) Method
EP2868476A4 (en) Printed-matter production method
HUE041327T2 (en) Method of forming a container
GB201305714D0 (en) Method
GB201317111D0 (en) Method of displaying a parameter
GB201301094D0 (en) Method
GB2537725B (en) Method of plugging a well
EP2987038A4 (en) Optimization of a process
HK1208864A1 (en) A preparation method of ecteinascidin-743 intermediate -743