SG11201504437SA - 6-CHLORO-3-(PHENYL-D<sb>5</sb>)-INDEN-1-ONE AND USE THEREOF - Google Patents
6-CHLORO-3-(PHENYL-D<sb>5</sb>)-INDEN-1-ONE AND USE THEREOFInfo
- Publication number
- SG11201504437SA SG11201504437SA SG11201504437SA SG11201504437SA SG11201504437SA SG 11201504437S A SG11201504437S A SG 11201504437SA SG 11201504437S A SG11201504437S A SG 11201504437SA SG 11201504437S A SG11201504437S A SG 11201504437SA SG 11201504437S A SG11201504437S A SG 11201504437SA
- Authority
- SG
- Singapore
- Prior art keywords
- inden
- chloro
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261739095P | 2012-12-19 | 2012-12-19 | |
| DKPA201200811 | 2012-12-19 | ||
| PCT/EP2013/077314 WO2014096151A2 (en) | 2012-12-19 | 2013-12-19 | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201504437SA true SG11201504437SA (en) | 2015-07-30 |
Family
ID=59295365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201504437SA SG11201504437SA (en) | 2012-12-19 | 2013-12-19 | 6-CHLORO-3-(PHENYL-D<sb>5</sb>)-INDEN-1-ONE AND USE THEREOF |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9309165B2 (ko) |
| EP (1) | EP2943460B1 (ko) |
| JP (1) | JP6290921B2 (ko) |
| KR (1) | KR102212096B1 (ko) |
| CN (1) | CN104955796B (ko) |
| AR (1) | AR094054A1 (ko) |
| AU (1) | AU2013366693B2 (ko) |
| BR (1) | BR112015014384A2 (ko) |
| CA (1) | CA2893224C (ko) |
| CL (1) | CL2015001720A1 (ko) |
| CY (1) | CY1122715T1 (ko) |
| DK (1) | DK2943460T3 (ko) |
| HK (1) | HK1217688A1 (ko) |
| HR (1) | HRP20200385T1 (ko) |
| IL (1) | IL239097A (ko) |
| LT (1) | LT2943460T (ko) |
| MX (1) | MX365707B (ko) |
| PL (1) | PL2943460T3 (ko) |
| PT (1) | PT2943460T (ko) |
| RS (1) | RS59982B1 (ko) |
| RU (1) | RU2681221C2 (ko) |
| SG (1) | SG11201504437SA (ko) |
| SI (1) | SI2943460T1 (ko) |
| WO (1) | WO2014096151A2 (ko) |
| ZA (1) | ZA201504405B (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104628630B (zh) * | 2015-03-16 | 2017-01-18 | 哈尔滨工业大学 | 一种茚衍生物1‑吡啶基‑2‑溴茚及其合成方法 |
| CN104892492A (zh) * | 2015-06-18 | 2015-09-09 | 哈尔滨工业大学 | 一种茚衍生物1-吡啶基-6-甲基茚及其合成方法 |
| JP2021520382A (ja) * | 2018-04-06 | 2021-08-19 | ハー・ルンドベック・アクチエゼルスカベット | ２，２−ジメチルピペラジンの調製方法 |
| US20210395208A1 (en) * | 2018-10-29 | 2021-12-23 | H. Lundeck A/S | Amorphous compounds of formula (i) and amorphous compounds of formula (i) salts |
| WO2020114853A1 (en) | 2018-12-03 | 2020-06-11 | H. Lundbeck A/S | Prodrugs of 4-((1r,3s)-6-chloro-3-phenyl-2,3-dihydro-1h-inden-1-yl)-1,2,2-trimethylpiperazine and 4-((1/r,3s)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1h-inden-1-yl)-2,2-dimethy-1-(methyl-d3)piperazine |
| KR102051783B1 (ko) * | 2019-09-02 | 2019-12-03 | 부산대학교 산학협력단 | 3,10-이치환 벤조풀벤 유도체의 신규 합성방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR910003427B1 (ko) * | 1984-12-04 | 1991-05-31 | 산도즈 파마슈티칼스 코포레이션 | 메발로노락톤의 인덴동족체 및 이들의 유도체의 제법 |
| DE19538218A1 (de) * | 1995-10-13 | 1997-04-17 | Bayer Ag | Cyclopentan-1,3-dion-Derivate |
| WO1999015524A1 (en) * | 1997-09-23 | 1999-04-01 | Fujisawa Pharmaceutical Co., Ltd. | Thiazole derivatives |
| SE9904850D0 (sv) * | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| AU2004265021B2 (en) | 2003-08-18 | 2010-05-27 | H. Lundbeck A/S | Succinate and malonate salt of trans-4-(IR,3S)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament |
| RU2366654C2 (ru) * | 2004-06-08 | 2009-09-10 | ЭнЭсЭйБи, ФИЛИАЛ АФ НЕУРОСЕРЧ СВИДЕН АБ, СВЕРИЙЕ | Новые дизамещенные фенилпиперидины/пиперазины в качестве модуляторов допаминовой нейротрансмиссии |
| TWI453198B (zh) * | 2005-02-16 | 2014-09-21 | Lundbeck & Co As H | 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s）-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法 |
| JP5301991B2 (ja) * | 2005-07-29 | 2013-09-25 | コンサート ファーマシューティカルズ インコーポレイテッド | 新規なベンゾ［ｄ］［１，３］−ジオキソール誘導体 |
| WO2008086158A1 (en) * | 2007-01-04 | 2008-07-17 | Smithkline Beecham Corporation | Benzodihydroquinazoline as pi3 kinase inhibitors |
| TW201102370A (en) | 2009-07-07 | 2011-01-16 | Lundbeck & Co As H | Manufacture of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-3,3-dimethyl piperazine |
| KR101149529B1 (ko) * | 2009-09-11 | 2012-05-25 | 한국화학연구원 | 인덴온 유도체 및 이를 포함하는 약학적 조성물 |
| EP2639216B1 (en) | 2010-11-09 | 2018-07-11 | Kaneka Corporation | Halogenated indenones and method for producing optically active indanones or optically active indanols by using same |
| CN103429577A (zh) | 2011-01-07 | 2013-12-04 | H.隆德贝克有限公司 | 4-((1r,3s)-6-氯-3-苯基-茚满-1-基)-1,2,2-三甲基哌嗪和1-((1r,3s)-6-氯-3-苯基-茚满-1-基)-3,3-二甲基哌嗪的拆分方法 |
| LT2720989T (lt) * | 2011-06-20 | 2016-11-25 | H. Lundbeck A/S | Deuterinti 1-piperazin-3-fenilindanai, skirti šizofrenijos gydymui |
-
2013
- 2013-12-17 AR ARP130104787A patent/AR094054A1/es active IP Right Grant
- 2013-12-19 CN CN201380065995.3A patent/CN104955796B/zh active Active
- 2013-12-19 DK DK13811511.8T patent/DK2943460T3/da active
- 2013-12-19 CA CA2893224A patent/CA2893224C/en active Active
- 2013-12-19 RU RU2015123308A patent/RU2681221C2/ru active
- 2013-12-19 JP JP2015548555A patent/JP6290921B2/ja active Active
- 2013-12-19 KR KR1020157015940A patent/KR102212096B1/ko active IP Right Grant
- 2013-12-19 SG SG11201504437SA patent/SG11201504437SA/en unknown
- 2013-12-19 BR BR112015014384A patent/BR112015014384A2/pt not_active Application Discontinuation
- 2013-12-19 AU AU2013366693A patent/AU2013366693B2/en active Active
- 2013-12-19 PT PT138115118T patent/PT2943460T/pt unknown
- 2013-12-19 WO PCT/EP2013/077314 patent/WO2014096151A2/en active Application Filing
- 2013-12-19 LT LTEP13811511.8T patent/LT2943460T/lt unknown
- 2013-12-19 EP EP13811511.8A patent/EP2943460B1/en active Active
- 2013-12-19 RS RS20200220A patent/RS59982B1/sr unknown
- 2013-12-19 MX MX2015007727A patent/MX365707B/es active IP Right Grant
- 2013-12-19 SI SI201331680T patent/SI2943460T1/sl unknown
- 2013-12-19 US US14/653,318 patent/US9309165B2/en active Active
- 2013-12-19 PL PL13811511T patent/PL2943460T3/pl unknown
-
2015
- 2015-05-31 IL IL239097A patent/IL239097A/en active IP Right Grant
- 2015-06-18 CL CL2015001720A patent/CL2015001720A1/es unknown
- 2015-06-18 ZA ZA2015/04405A patent/ZA201504405B/en unknown
-
2016
- 2016-05-18 HK HK16105696.8A patent/HK1217688A1/zh unknown
-
2020
- 2020-03-05 CY CY20201100198T patent/CY1122715T1/el unknown
- 2020-03-09 HR HRP20200385TT patent/HRP20200385T1/hr unknown
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