SG11201408539UA - Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof - Google Patents

Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof

Info

Publication number
SG11201408539UA
SG11201408539UA SG11201408539UA SG11201408539UA SG11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA
Authority
SG
Singapore
Prior art keywords
urolithin
international
urolithins
lausanne
precursors
Prior art date
Application number
SG11201408539UA
Other languages
English (en)
Inventor
William Blanco-Bose
Bernard Schneider
Christopher L Rinsch
Laurent Mouchiroud
Dongryeol Ryu
Penelope Andreux
Johan Auwerx
Original Assignee
Amazentis Sa
Christopher L Rinsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amazentis Sa, Christopher L Rinsch filed Critical Amazentis Sa
Publication of SG11201408539UA publication Critical patent/SG11201408539UA/en

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/132Amines having two or more amino groups, e.g. spermidine, putrescine
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • C07DHETEROCYCLIC COMPOUNDS
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    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Obesity (AREA)
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  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
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  • Pain & Pain Management (AREA)
  • Psychology (AREA)
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  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
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SG11201408539UA 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof SG11201408539UA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261665137P 2012-06-27 2012-06-27
US201261712886P 2012-10-12 2012-10-12
US201361791137P 2013-03-15 2013-03-15
PCT/US2013/048310 WO2014004902A2 (en) 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof

Publications (1)

Publication Number Publication Date
SG11201408539UA true SG11201408539UA (en) 2015-01-29

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ID=48782652

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Application Number Title Priority Date Filing Date
SG11201408539UA SG11201408539UA (en) 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof
SG10202106329TA SG10202106329TA (en) 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof
SG10201610798QA SG10201610798QA (en) 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10202106329TA SG10202106329TA (en) 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof
SG10201610798QA SG10201610798QA (en) 2012-06-27 2013-06-27 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof

Country Status (14)

Country Link
US (7) US11020373B2 (ko)
EP (2) EP4233858A1 (ko)
JP (4) JP6422163B2 (ko)
KR (4) KR20210128511A (ko)
CN (2) CN110934863A (ko)
AR (1) AR091604A1 (ko)
AU (5) AU2013284419A1 (ko)
BR (1) BR112014032809A8 (ko)
CA (2) CA2877718C (ko)
ES (1) ES2968368T3 (ko)
MX (3) MX2014016044A (ko)
PT (1) PT2866804T (ko)
SG (3) SG11201408539UA (ko)
WO (1) WO2014004902A2 (ko)

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SG11201408539UA (en) 2012-06-27 2015-01-29 Amazentis Sa Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof
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AU2014317857B2 (en) * 2013-09-09 2020-01-02 Natreon, Inc. Regulation of body weight gain by using dibenzo-alpha-pyrones
EP2862568A1 (en) * 2013-10-15 2015-04-22 Centre National de la Recherche Scientifique (CNRS) Compositions comprising urolithins and uses thereof for the stimulation of insulin secretion
EP3087065B1 (en) 2013-12-23 2020-01-22 Amazentis SA Synthesis of urolithins
GB201323008D0 (en) 2013-12-24 2014-02-12 Amazentis As Compounds and uses thereof
GB201413228D0 (en) 2014-07-25 2014-09-10 Nugerontix Ltd Polyphenol compositions
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JP2017014154A (ja) * 2015-07-01 2017-01-19 公立大学法人岡山県立大学 ウロリチン類を含有するヒアルロン酸産生促進剤
JP6799767B2 (ja) * 2015-07-07 2020-12-16 公立大学法人岡山県立大学 ウロリチン類を含有するメラニン産生抑制剤
GB201515391D0 (en) 2015-08-28 2015-10-14 Amazentis Sa Compositions
EP3393467B1 (en) * 2015-12-24 2020-07-01 Amazentis SA Compositions comprising nicotinamide riboside and a urolithin
JP6791478B2 (ja) * 2016-05-26 2020-11-25 株式会社ダイセル ウロリチン類を含有するアンジオテンシン変換酵素阻害剤
JP2017210444A (ja) * 2016-05-26 2017-11-30 株式会社ダイセル ウロリチン類を含有するリパーゼ阻害剤
EP3478091B1 (en) * 2016-06-29 2024-03-20 Halo Life Science, LLC Method of preparing a low odor dicholinium ellagate salt and other low odor organic salts of choline
US10774328B2 (en) 2016-07-11 2020-09-15 University Of North Texas Health Science Center At Fort Worth Treatment for glaucoma and other eye diseases
WO2018085419A1 (en) 2016-11-01 2018-05-11 Jian Feng Method of producing naive pluripotent stem cells
EP3354645A1 (en) 2017-01-26 2018-08-01 Patheon Austria GmbH & Co KG Process for preparing urolithins
WO2018162645A1 (en) 2017-03-08 2018-09-13 Amazentis Sa Skin treatment methods
WO2018162651A1 (en) 2017-03-08 2018-09-13 Amazentis Sa Methods for improving mitophagy in subjects
WO2018162650A1 (en) 2017-03-08 2018-09-13 Amazentis Sa Methods for improving mitophagy in subjects
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WO2019121855A1 (en) * 2017-12-20 2019-06-27 Societe Des Produits Nestle S.A. Compositions and methods using high protein for induction of autophagy
CA3089695A1 (en) * 2018-02-19 2019-08-22 Natreon, Inc. Synergistic combinations of urolithins a and b for improving cognitive capacity or cognitive function
WO2019163437A1 (ja) 2018-02-21 2019-08-29 株式会社ダイセル ウロリチン類を含有する破骨細胞分化抑制剤
WO2019187918A1 (ja) * 2018-03-29 2019-10-03 国立大学法人 琉球大学 分化コントロール化合物を用いて造腫瘍性をもつおそれのある未分化iPS細胞等の混入を除去する方法
WO2019211294A1 (en) 2018-04-30 2019-11-07 Amazentis Sa Urolithin a as immune enhancer
AU2019269401A1 (en) * 2018-05-15 2021-01-07 The Institute For Stem Cell Biology And Regenerative Medicine (Instem) Urolithin A and derivatives thereof for use in therapy
JP2021527048A (ja) * 2018-06-05 2021-10-11 フラッグシップ パイオニアリング イノベーションズ ブイ, インコーポレイテッド 癌治療のためのアシル化カテキンポリフェノールおよびその使用方法
EP3801496A4 (en) 2018-06-05 2022-07-06 Flagship Pioneering Innovations V, Inc. ACTIVE AGENTS AND METHODS OF USE THEREOF FOR TREATING METABOLIC DISORDERS AND NAFLD
CN108676013B (zh) * 2018-06-25 2021-01-01 中国医学科学院医药生物技术研究所 具有自噬激活活性的黄醇酮类化合物、其制备方法及其制药应用
CN109316478A (zh) * 2018-11-06 2019-02-12 上海出入境检验检疫局动植物与食品检验检疫技术中心 一种尿石素a在制备抗衰老的药物、化妆品中的应用及药物、化妆品
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