SG11201408539UA - Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof - Google Patents
Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereofInfo
- Publication number
- SG11201408539UA SG11201408539UA SG11201408539UA SG11201408539UA SG11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA SG 11201408539U A SG11201408539U A SG 11201408539UA
- Authority
- SG
- Singapore
- Prior art keywords
- urolithin
- international
- urolithins
- lausanne
- precursors
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
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- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261665137P | 2012-06-27 | 2012-06-27 | |
US201261712886P | 2012-10-12 | 2012-10-12 | |
US201361791137P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/048310 WO2014004902A2 (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201408539UA true SG11201408539UA (en) | 2015-01-29 |
Family
ID=48782652
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201408539UA SG11201408539UA (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
SG10202106329TA SG10202106329TA (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
SG10201610798QA SG10201610798QA (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202106329TA SG10202106329TA (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
SG10201610798QA SG10201610798QA (en) | 2012-06-27 | 2013-06-27 | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
Country Status (14)
Country | Link |
---|---|
US (7) | US11020373B2 (ko) |
EP (2) | EP4233858A1 (ko) |
JP (4) | JP6422163B2 (ko) |
KR (4) | KR20210128511A (ko) |
CN (2) | CN110934863A (ko) |
AR (1) | AR091604A1 (ko) |
AU (5) | AU2013284419A1 (ko) |
BR (1) | BR112014032809A8 (ko) |
CA (2) | CA2877718C (ko) |
ES (1) | ES2968368T3 (ko) |
MX (3) | MX2014016044A (ko) |
PT (1) | PT2866804T (ko) |
SG (3) | SG11201408539UA (ko) |
WO (1) | WO2014004902A2 (ko) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201408539UA (en) | 2012-06-27 | 2015-01-29 | Amazentis Sa | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
CA2895914C (en) * | 2013-01-18 | 2023-06-20 | Procell Sprl | Urolithin b with testosterone, leucine and/or creatine for muscle growth |
AU2014317857B2 (en) * | 2013-09-09 | 2020-01-02 | Natreon, Inc. | Regulation of body weight gain by using dibenzo-alpha-pyrones |
EP2862568A1 (en) * | 2013-10-15 | 2015-04-22 | Centre National de la Recherche Scientifique (CNRS) | Compositions comprising urolithins and uses thereof for the stimulation of insulin secretion |
EP3087065B1 (en) | 2013-12-23 | 2020-01-22 | Amazentis SA | Synthesis of urolithins |
GB201323008D0 (en) | 2013-12-24 | 2014-02-12 | Amazentis As | Compounds and uses thereof |
GB201413228D0 (en) | 2014-07-25 | 2014-09-10 | Nugerontix Ltd | Polyphenol compositions |
US20170367390A1 (en) * | 2014-12-19 | 2017-12-28 | Halo Life Science, Llc | Use of ellagic acid dihydrate in food products and nutraceuticals |
ES2902017T3 (es) * | 2015-04-13 | 2022-03-24 | Sumitomo Seika Chemicals | Método de producción de ácidos benzoicos 2-halogenados |
JP6740548B2 (ja) * | 2015-05-15 | 2020-08-19 | 公立大学法人岡山県立大学 | ウロリチン類を含有する育毛剤、及び、ウロリチン類を含有する5αレダクターゼ活性阻害剤 |
JP2017014154A (ja) * | 2015-07-01 | 2017-01-19 | 公立大学法人岡山県立大学 | ウロリチン類を含有するヒアルロン酸産生促進剤 |
JP6799767B2 (ja) * | 2015-07-07 | 2020-12-16 | 公立大学法人岡山県立大学 | ウロリチン類を含有するメラニン産生抑制剤 |
GB201515391D0 (en) | 2015-08-28 | 2015-10-14 | Amazentis Sa | Compositions |
EP3393467B1 (en) * | 2015-12-24 | 2020-07-01 | Amazentis SA | Compositions comprising nicotinamide riboside and a urolithin |
JP6791478B2 (ja) * | 2016-05-26 | 2020-11-25 | 株式会社ダイセル | ウロリチン類を含有するアンジオテンシン変換酵素阻害剤 |
JP2017210444A (ja) * | 2016-05-26 | 2017-11-30 | 株式会社ダイセル | ウロリチン類を含有するリパーゼ阻害剤 |
EP3478091B1 (en) * | 2016-06-29 | 2024-03-20 | Halo Life Science, LLC | Method of preparing a low odor dicholinium ellagate salt and other low odor organic salts of choline |
US10774328B2 (en) | 2016-07-11 | 2020-09-15 | University Of North Texas Health Science Center At Fort Worth | Treatment for glaucoma and other eye diseases |
WO2018085419A1 (en) | 2016-11-01 | 2018-05-11 | Jian Feng | Method of producing naive pluripotent stem cells |
EP3354645A1 (en) | 2017-01-26 | 2018-08-01 | Patheon Austria GmbH & Co KG | Process for preparing urolithins |
WO2018162645A1 (en) | 2017-03-08 | 2018-09-13 | Amazentis Sa | Skin treatment methods |
WO2018162651A1 (en) | 2017-03-08 | 2018-09-13 | Amazentis Sa | Methods for improving mitophagy in subjects |
WO2018162650A1 (en) | 2017-03-08 | 2018-09-13 | Amazentis Sa | Methods for improving mitophagy in subjects |
JP2019097566A (ja) * | 2017-12-07 | 2019-06-24 | 大正製薬株式会社 | 体内時計調整用組成物 |
JP7434155B2 (ja) * | 2017-12-20 | 2024-02-20 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | オートファジーの誘導のためにオートファジー誘導因子と高タンパク質との組み合わせを使用する組成物及び方法 |
WO2019121855A1 (en) * | 2017-12-20 | 2019-06-27 | Societe Des Produits Nestle S.A. | Compositions and methods using high protein for induction of autophagy |
CA3089695A1 (en) * | 2018-02-19 | 2019-08-22 | Natreon, Inc. | Synergistic combinations of urolithins a and b for improving cognitive capacity or cognitive function |
WO2019163437A1 (ja) | 2018-02-21 | 2019-08-29 | 株式会社ダイセル | ウロリチン類を含有する破骨細胞分化抑制剤 |
WO2019187918A1 (ja) * | 2018-03-29 | 2019-10-03 | 国立大学法人 琉球大学 | 分化コントロール化合物を用いて造腫瘍性をもつおそれのある未分化iPS細胞等の混入を除去する方法 |
WO2019211294A1 (en) | 2018-04-30 | 2019-11-07 | Amazentis Sa | Urolithin a as immune enhancer |
AU2019269401A1 (en) * | 2018-05-15 | 2021-01-07 | The Institute For Stem Cell Biology And Regenerative Medicine (Instem) | Urolithin A and derivatives thereof for use in therapy |
JP2021527048A (ja) * | 2018-06-05 | 2021-10-11 | フラッグシップ パイオニアリング イノベーションズ ブイ, インコーポレイテッド | 癌治療のためのアシル化カテキンポリフェノールおよびその使用方法 |
EP3801496A4 (en) | 2018-06-05 | 2022-07-06 | Flagship Pioneering Innovations V, Inc. | ACTIVE AGENTS AND METHODS OF USE THEREOF FOR TREATING METABOLIC DISORDERS AND NAFLD |
CN108676013B (zh) * | 2018-06-25 | 2021-01-01 | 中国医学科学院医药生物技术研究所 | 具有自噬激活活性的黄醇酮类化合物、其制备方法及其制药应用 |
CN109316478A (zh) * | 2018-11-06 | 2019-02-12 | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 一种尿石素a在制备抗衰老的药物、化妆品中的应用及药物、化妆品 |
CN113260360A (zh) * | 2019-01-18 | 2021-08-13 | 雀巢产品有限公司 | 用于增加干细胞功能的试剂和方法 |
CN110066284B (zh) * | 2019-02-01 | 2021-06-04 | 贵阳倍隆生物科技有限公司 | 一种一锅法合成鞣花酸的方法 |
CN110229167B (zh) * | 2019-05-22 | 2020-11-24 | 珠海萱嘉君行健康产业发展有限公司 | 一种利用五倍子制备鞣花酸的方法、制得的鞣花酸及其应用 |
CN111995610A (zh) * | 2019-05-27 | 2020-11-27 | 首都医科大学 | 一种尿石素类化合物用于治疗胶质母细胞瘤药物的应用 |
US20200397807A1 (en) * | 2019-06-18 | 2020-12-24 | MitoPower, LLC | Nicotinyl riboside compounds and their uses |
US20220184015A1 (en) * | 2019-06-20 | 2022-06-16 | Societe Des Produits Nestle S.A. | Compositions and methods to potentiate musculoskeletal effect of one or more anabolic amino acids on bone health |
GB201912107D0 (en) | 2019-08-22 | 2019-10-09 | Amazentis Sa | Combination |
GB201915191D0 (en) * | 2019-10-21 | 2019-12-04 | Floratek Gmbh | Novel heterocyclic compounds |
GB201916046D0 (en) | 2019-11-04 | 2019-12-18 | Amazentis Sa | Diagnostic method |
CN114760996A (zh) * | 2019-11-27 | 2022-07-15 | 雀巢产品有限公司 | 与间接ampk活化剂化合物组合的直接ampk活化剂化合物、组合物、方法和其用途 |
US20230048350A1 (en) * | 2019-11-27 | 2023-02-16 | Societe Des Produits Nestle S.A. | Benzocoumarin ampk activator compounds, compositions, methods and uses thereof |
CN113018305A (zh) * | 2019-12-24 | 2021-06-25 | 兰州大学 | 一种化合物在制备治疗阿尔兹海默症药物中的应用 |
JP2023520299A (ja) * | 2020-02-20 | 2023-05-17 | ザ ロイヤル インスティチューション フォー ジ アドヴァンスメント オブ ラーニング/マギル ユニヴァーシティ | 抗がん有効性のための、及び免疫チェックポイント阻害剤に対する応答を増加させるための、カスタラギン又はその類似体の使用 |
US20240000753A1 (en) * | 2020-07-17 | 2024-01-04 | The Trustees Of Columbia University In The City Of New York | Methods and compositions to increase lifespan and healthspan by mimicking the effects of time-restricted feeding |
CN111983058B (zh) * | 2020-07-30 | 2023-06-23 | 云南中医药大学 | 中药抗非酒精性脂肪肝活性物质的筛选方法 |
US20220071952A1 (en) * | 2020-09-04 | 2022-03-10 | Natreon, Inc. | Methods of treating and preventing hepatotoxicity |
CA3188397A1 (en) | 2020-09-25 | 2022-03-31 | Anupama Dattatreya | Compositions and methods using xanthan gum to stabilize at least one urolithin in an aqueous matrix |
KR102623664B1 (ko) | 2020-12-10 | 2024-01-12 | 서울대학교산학협력단 | 유로리틴 a를 이용한 당뇨성 알츠하이머병의 치료 조성물 및 치료 방법 |
BR112023014973A2 (pt) | 2021-01-27 | 2023-11-07 | Vandria Sa | Derivados de urolitina e métodos de uso dos mesmos |
CN112716938A (zh) * | 2021-02-25 | 2021-04-30 | 新疆医科大学 | 鞣花酸在制备缓解眼组织病变的药物中的用途 |
KR102677423B1 (ko) * | 2021-09-17 | 2024-06-21 | 조선대학교산학협력단 | 망기페린을 포함하는 자가포식 활성화용 조성물 |
KR102690860B1 (ko) * | 2021-10-13 | 2024-08-05 | 한국해양과학기술원 | 남극 진균 균주 Pleosporales sp. SF-7343 유래 대사화합물을 포함하는 염증질환 예방 또는 치료용 조성물 |
WO2023073079A1 (en) * | 2021-10-28 | 2023-05-04 | Société des Produits Nestlé S.A. | Compositions and methods using a combination of nutrients to support cognition and emotional health in a mammal |
WO2023161453A1 (en) | 2022-02-24 | 2023-08-31 | Amazentis Sa | Uses of urolithins |
US20230301890A1 (en) | 2022-03-22 | 2023-09-28 | Amazentis Sa | Compositions comprising urolithins |
WO2023237926A2 (en) * | 2022-06-06 | 2023-12-14 | Amazentis Sa | Urolithins for improving cardiac function and health |
WO2024025953A2 (en) * | 2022-07-27 | 2024-02-01 | Vandria Sa | Therapeutic uses of urolithin derivatives |
CN115433151A (zh) * | 2022-09-02 | 2022-12-06 | 苏州大学 | 一种6,7,8-三羟基香豆素的制备方法 |
CN115581689B (zh) * | 2022-10-17 | 2024-05-14 | 常州大学 | 尿石素b酰胺类衍生物的应用 |
GB202219317D0 (en) | 2022-12-20 | 2023-02-01 | Amazentis Sa | Methods for improving mitophagy in subjects |
CN117771237B (zh) * | 2024-02-27 | 2024-05-03 | 南昌医学院 | 一种松香烷型二萜化合物的用途和制备方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6479103A (en) | 1987-06-09 | 1989-03-24 | Lion Corp | External preparation |
CA2338638C (en) | 1998-07-30 | 2009-03-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of l-carnitine and its alkanoyl derivatives in the preparation of medicaments with anticancer activity |
US6440436B1 (en) | 2001-05-18 | 2002-08-27 | Natreon Inc. | Process for preparing purified shilajit composition from native shilajit |
US20050171079A1 (en) | 2004-02-04 | 2005-08-04 | Schrimpf Michael R. | Amino-substituted tricyclic derivatives and methods of use |
US7365193B2 (en) | 2004-02-04 | 2008-04-29 | Abbott Laboratories | Amino-substituted tricyclic derivatives and methods of use |
US20050282781A1 (en) | 2004-06-18 | 2005-12-22 | Shibnath Ghosal | Compositions of stable bioactive metabolites of docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids |
US20060257337A1 (en) | 2005-04-28 | 2006-11-16 | David Sherris | Compositions and methods to treat skin diseases characterized by cellular proliferation and angiogenesis |
EP1996021B1 (en) | 2006-02-28 | 2017-12-13 | Paloma Pharmaceuticals, Inc. | Compositions and methods to treat diseases characterized by cellular proliferation and angiogenesis |
WO2007127263A2 (en) * | 2006-04-26 | 2007-11-08 | The Regents Of The University Of California | Therapeutic uses of urolithins |
US8894993B2 (en) | 2006-08-04 | 2014-11-25 | Natreon Inc. | Mitochondria-targeted antioxidants |
EP2155154A2 (fr) * | 2007-05-11 | 2010-02-24 | Galderma Research & Development | Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations |
TW200929211A (en) | 2007-12-17 | 2009-07-01 | Etron Technology Inc | Method of reducing current of memory in self-refreshing mode |
US8642660B2 (en) * | 2007-12-21 | 2014-02-04 | The University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
US20110021618A1 (en) | 2008-03-25 | 2011-01-27 | Paloma Pharmaceuticals, Inc. | Methods of treating fibrotic disorders |
JP5385686B2 (ja) | 2009-06-05 | 2014-01-08 | サントリーホールディングス株式会社 | 血小板凝集抑制剤 |
CN102762573B (zh) * | 2009-07-24 | 2015-09-16 | 阿马曾提斯公司 | 用于在神经退行性障碍中保护脑部健康的化合物、组合物和方法 |
RU2606763C2 (ru) * | 2010-12-23 | 2017-01-10 | Амазентис Са | Композиции и способы для усиления или поддержания мышечной деятельности |
US20130324595A1 (en) | 2011-02-22 | 2013-12-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | C-glucosidic ellagitannin compounds for use for altering the supramolecular arrangement of actin and for the treatment of osteoporosis, cancer, bacterial infection and viral infection |
SG11201408539UA (en) | 2012-06-27 | 2015-01-29 | Amazentis Sa | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
EP3393467B1 (en) | 2015-12-24 | 2020-07-01 | Amazentis SA | Compositions comprising nicotinamide riboside and a urolithin |
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