SG11201400125RA - Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease - Google Patents
Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's diseaseInfo
- Publication number
- SG11201400125RA SG11201400125RA SG11201400125RA SG11201400125RA SG11201400125RA SG 11201400125R A SG11201400125R A SG 11201400125RA SG 11201400125R A SG11201400125R A SG 11201400125RA SG 11201400125R A SG11201400125R A SG 11201400125RA SG 11201400125R A SG11201400125R A SG 11201400125RA
- Authority
- SG
- Singapore
- Prior art keywords
- tau
- alzheimer
- diagnosis
- protein
- disease
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
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- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161536339P | 2011-09-19 | 2011-09-19 | |
US201261653115P | 2012-05-30 | 2012-05-30 | |
PCT/IB2012/002246 WO2013041962A1 (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201400125RA true SG11201400125RA (en) | 2014-03-28 |
Family
ID=47216372
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201912964PA SG10201912964PA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
SG10201703771WA SG10201703771WA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
SG10201912955PA SG10201912955PA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
SG11201400125RA SG11201400125RA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201912964PA SG10201912964PA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
SG10201703771WA SG10201703771WA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
SG10201912955PA SG10201912955PA (en) | 2011-09-19 | 2012-09-14 | Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease |
Country Status (30)
Country | Link |
---|---|
US (5) | US9518101B2 (zh) |
EP (2) | EP2758433B1 (zh) |
JP (7) | JP6253583B2 (zh) |
KR (3) | KR102130439B1 (zh) |
CN (3) | CN115417916A (zh) |
AU (3) | AU2012311234B2 (zh) |
BR (1) | BR112014006376B1 (zh) |
CA (1) | CA2848346A1 (zh) |
CL (3) | CL2014000679A1 (zh) |
CY (1) | CY1119792T1 (zh) |
DK (1) | DK2758433T3 (zh) |
ES (1) | ES2656442T3 (zh) |
HK (1) | HK1199459A1 (zh) |
HR (1) | HRP20180083T8 (zh) |
HU (1) | HUE036177T2 (zh) |
IL (4) | IL231201B (zh) |
LT (1) | LT2758433T (zh) |
ME (1) | ME03008B (zh) |
MX (1) | MX347505B (zh) |
MY (1) | MY183989A (zh) |
PL (1) | PL2758433T3 (zh) |
PT (1) | PT2758433T (zh) |
RS (1) | RS56852B1 (zh) |
RU (2) | RU2018102103A (zh) |
SG (4) | SG10201912964PA (zh) |
SI (1) | SI2758433T1 (zh) |
TR (1) | TR201800669T4 (zh) |
UA (2) | UA115657C2 (zh) |
WO (1) | WO2013041962A1 (zh) |
ZA (1) | ZA201401333B (zh) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2826286C (en) * | 2011-01-31 | 2021-09-21 | Intellect Neurosciences Inc. | Treatment of tauopathies |
SG11201408626YA (en) | 2012-07-03 | 2015-03-30 | Univ Washington | Antibodies to tau |
MX359817B (es) | 2012-08-16 | 2018-10-11 | Ipierian Inc | Anticuerpos que se enlazan a tau. |
US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
CA2902026C (en) | 2013-03-13 | 2023-08-29 | Prothena Biosciences Limited | Tau immunotherapy |
WO2015081085A2 (en) * | 2013-11-27 | 2015-06-04 | Ipierian, Inc. | Methods of treating a tauopathy |
WO2015098963A1 (ja) * | 2013-12-26 | 2015-07-02 | 東亞合成株式会社 | カルレティキュリンの発現促進方法および該方法に用いられる合成ペプチド |
EP3104870A4 (en) | 2014-02-14 | 2017-09-13 | Ipierian, Inc. | Tau peptides, anti-tau antibodies, and methods of use thereof |
BR112016030183A2 (pt) * | 2014-06-26 | 2017-11-14 | Janssen Vaccines & Prevention Bv | anticorpos e fragmentos de ligação ao antígeno que se ligam especificamente à proteína tau associada a microtúbulos |
ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
TWI734975B (zh) | 2014-06-27 | 2021-08-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
EP3760235A1 (en) | 2014-09-30 | 2021-01-06 | Washington University | Tau kinetic measurements |
BR112017010498A2 (pt) * | 2014-11-19 | 2017-12-26 | Axon Neuroscience Se | anticorpos tau humanizados em doença de alzheimer |
JO3576B1 (ar) | 2015-02-26 | 2020-07-05 | Lilly Co Eli | أجسام مضادة لـ tau واستخداماتها |
IL300670A (en) | 2015-06-05 | 2023-04-01 | Genentech Inc | Anti-tau antibodies and methods of use |
UA124616C2 (uk) | 2015-07-06 | 2021-10-20 | Юсб Біофарма Срл | Зв'язуюче тау-білок антитіло |
PE20180499A1 (es) | 2015-07-06 | 2018-03-09 | Ucb Biopharma Sprl | Anticuerpos de union a tau |
JO3711B1 (ar) * | 2015-07-13 | 2021-01-31 | H Lundbeck As | أجسام مضادة محددة لبروتين تاو وطرق استعمالها |
GB201518675D0 (en) * | 2015-10-21 | 2015-12-02 | Cellcap Technologies Ltd | Detection of structural forms of proteins |
US11326182B2 (en) | 2016-04-29 | 2022-05-10 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR THE TREATMENT OF DISEASES |
PE20190261A1 (es) * | 2016-05-02 | 2019-02-25 | Prothena Biosciences Ltd | Anticuerpos que reconocen tau |
HUE060258T2 (hu) * | 2016-05-02 | 2023-02-28 | Prothena Biosciences Ltd | Tau immunterápia |
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