SG10201914132RA - Anti-cd40 antibodies and their uses - Google Patents
Anti-cd40 antibodies and their usesInfo
- Publication number
- SG10201914132RA SG10201914132RA SG10201914132RA SG10201914132RA SG10201914132RA SG 10201914132R A SG10201914132R A SG 10201914132RA SG 10201914132R A SG10201914132R A SG 10201914132RA SG 10201914132R A SG10201914132R A SG 10201914132RA SG 10201914132R A SG10201914132R A SG 10201914132RA
- Authority
- SG
- Singapore
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662342417P | 2016-05-27 | 2016-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201914132RA true SG10201914132RA (en) | 2020-03-30 |
Family
ID=59014833
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201810522UA SG11201810522UA (en) | 2016-05-27 | 2017-05-26 | Anti-cd40 antibodies and their uses |
SG10201914132RA SG10201914132RA (en) | 2016-05-27 | 2017-05-26 | Anti-cd40 antibodies and their uses |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201810522UA SG11201810522UA (en) | 2016-05-27 | 2017-05-26 | Anti-cd40 antibodies and their uses |
Country Status (34)
Country | Link |
---|---|
US (8) | US10519243B2 (he) |
EP (2) | EP3464361B1 (he) |
JP (2) | JP2019523221A (he) |
KR (2) | KR102366355B1 (he) |
CN (1) | CN109476750B (he) |
AR (2) | AR108611A1 (he) |
AU (1) | AU2017271602A1 (he) |
BR (1) | BR112018074468A2 (he) |
CA (1) | CA3025347A1 (he) |
CL (1) | CL2018003366A1 (he) |
CO (1) | CO2018012699A2 (he) |
CR (1) | CR20180605A (he) |
CY (1) | CY1124806T1 (he) |
DO (1) | DOP2018000258A (he) |
EC (1) | ECSP18094829A (he) |
ES (1) | ES2901722T3 (he) |
HR (1) | HRP20211882T1 (he) |
HU (1) | HUE056670T2 (he) |
IL (1) | IL263223B2 (he) |
LT (1) | LT3464361T (he) |
MX (1) | MX2018014630A (he) |
MY (1) | MY195442A (he) |
NZ (1) | NZ748644A (he) |
PE (1) | PE20190970A1 (he) |
PH (1) | PH12018502456A1 (he) |
PL (1) | PL3464361T3 (he) |
PT (1) | PT3464361T (he) |
RS (1) | RS62726B1 (he) |
RU (1) | RU2752049C2 (he) |
SG (2) | SG11201810522UA (he) |
SI (1) | SI3464361T1 (he) |
TW (2) | TWI761348B (he) |
UA (1) | UA123111C2 (he) |
WO (1) | WO2017205742A1 (he) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2214701T3 (en) * | 2007-11-01 | 2016-12-12 | Univ Arkansas | CONFIGURATIONS AND METHODS FOR IMPROVING THE IMMUNE RESPONSES TO Eimeria |
ES2901722T3 (es) * | 2016-05-27 | 2022-03-23 | Abbvie Biotherapeutics Inc | Anticuerpos anti-CD40 y sus usos |
WO2019204756A1 (en) | 2018-04-20 | 2019-10-24 | Lyvgen Biopharma Co., Ltd. | Anti-cd40 antibodies and uses thereof |
CA3119865A1 (en) | 2018-11-23 | 2020-05-28 | Strike Pharma Ab | Bi-specific conjugates |
KR20210099027A (ko) * | 2018-11-30 | 2021-08-11 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | 항-cd40 항체, 이의 항원-결합 단편 및 약학적 용도 |
CN109912717B (zh) * | 2019-03-04 | 2020-05-26 | 北京天广实生物技术股份有限公司 | 结合cd40的抗体及其用途 |
US20220175920A1 (en) | 2019-03-27 | 2022-06-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Recombinant proteins with cd40 activating properties |
SG11202111188VA (en) * | 2019-04-10 | 2021-11-29 | Univ Nankai | Anti-cd40 antibody and use thereof |
WO2021048135A1 (en) | 2019-09-09 | 2021-03-18 | Basilea Pharmaceutica International AG | Pharmaceutical combinations comprising a furazanobenzimidazoles and a cd40 agonist for use in the treatment of neoplastic diseases |
KR20220062036A (ko) * | 2019-09-11 | 2022-05-13 | 노파르티스 아게 | 환자에서 인간 바이러스 연관된 장애를 방지하는 방법 |
KR20220103957A (ko) * | 2019-10-23 | 2022-07-25 | 리브젠 바이오파마 홀딩스 리미티드 | 항-cd40 결합 분자 및 이를 포함하는 이중-특이적 항체 |
CA3157516A1 (en) * | 2019-11-08 | 2021-05-14 | Xinyan Zhao | Anti-human programmed cell death ligand-1 (pd-l1) antibody and use thereof |
IL293450A (he) * | 2019-12-03 | 2022-07-01 | Evotec Int Gmbh | חלבונים קושרי אנטיגן קשורים לאינטרפרון ושימושים בהם |
GB202008003D0 (en) | 2020-05-28 | 2020-07-15 | Quine Medical Ab | Anti-CD40 antibody |
EP4185320A1 (en) * | 2020-07-23 | 2023-05-31 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof in treating muscle atrophy |
CN115403670A (zh) * | 2021-05-26 | 2022-11-29 | 安徽瀚海博兴生物技术有限公司 | 抗cd40抗体及其用途 |
WO2024059899A1 (en) * | 2022-09-20 | 2024-03-28 | Currus Biologics Pty Ltd | Bispecific polypeptides and uses thereof |
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DK2914627T3 (da) * | 2012-10-30 | 2021-07-12 | Apexigen Inc | Anti-cd40-antistoffer og fremgangsmåder til anvendelse |
EP2970436B1 (en) * | 2013-03-15 | 2018-09-05 | AbbVie Biotherapeutics Inc. | Fc variants |
GB201322583D0 (en) * | 2013-12-19 | 2014-02-05 | Alligator Bioscience Ab | Antibodies |
HUE054075T2 (hu) | 2014-10-29 | 2021-08-30 | Seagen Inc | CD40 elleni nem fukozilált antitestek adagolása és bevitele |
EP4047022A1 (en) * | 2015-05-29 | 2022-08-24 | AbbVie Inc. | Anti-cd40 antibodies and uses thereof |
ES2901722T3 (es) * | 2016-05-27 | 2022-03-23 | Abbvie Biotherapeutics Inc | Anticuerpos anti-CD40 y sus usos |
EP3464367B1 (en) * | 2016-05-27 | 2020-09-09 | AbbVie Biotherapeutics Inc. | Bispecific binding proteins binding an immunomodulatory protein and a tumor antigen |
-
2017
- 2017-05-26 ES ES17728411T patent/ES2901722T3/es active Active
- 2017-05-26 RU RU2018146533A patent/RU2752049C2/ru active
- 2017-05-26 KR KR1020187037322A patent/KR102366355B1/ko active IP Right Grant
- 2017-05-26 SG SG11201810522UA patent/SG11201810522UA/en unknown
- 2017-05-26 WO PCT/US2017/034681 patent/WO2017205742A1/en active Application Filing
- 2017-05-26 RS RS20211552A patent/RS62726B1/sr unknown
- 2017-05-26 HU HUE17728411A patent/HUE056670T2/hu unknown
- 2017-05-26 TW TW106117521A patent/TWI761348B/zh active
- 2017-05-26 SI SI201731001T patent/SI3464361T1/sl unknown
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