SG10201913250SA - Clinical formulations - Google Patents

Clinical formulations

Info

Publication number
SG10201913250SA
SG10201913250SA SG10201913250SA SG10201913250SA SG10201913250SA SG 10201913250S A SG10201913250S A SG 10201913250SA SG 10201913250S A SG10201913250S A SG 10201913250SA SG 10201913250S A SG10201913250S A SG 10201913250SA SG 10201913250S A SG10201913250S A SG 10201913250SA
Authority
SG
Singapore
Prior art keywords
clinical formulations
formulations
clinical
Prior art date
Application number
SG10201913250SA
Other languages
English (en)
Inventor
Roger Gay
Romma Southwick
Judson Ratliff
Original Assignee
Astellas Inst For Regenerative Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Inst For Regenerative Medicine filed Critical Astellas Inst For Regenerative Medicine
Publication of SG10201913250SA publication Critical patent/SG10201913250SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Dentistry (AREA)
SG10201913250SA 2015-08-18 2016-08-18 Clinical formulations SG10201913250SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562206821P 2015-08-18 2015-08-18

Publications (1)

Publication Number Publication Date
SG10201913250SA true SG10201913250SA (en) 2020-03-30

Family

ID=56843032

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201913250SA SG10201913250SA (en) 2015-08-18 2016-08-18 Clinical formulations

Country Status (16)

Country Link
US (2) US11013808B2 (tr)
EP (1) EP3334415A1 (tr)
JP (3) JP7043392B2 (tr)
KR (3) KR102651291B1 (tr)
CN (1) CN108697641A (tr)
AU (2) AU2016308818B2 (tr)
BR (1) BR112018003031B1 (tr)
CA (1) CA2995977A1 (tr)
EA (2) EA202190722A1 (tr)
HK (1) HK1256839A1 (tr)
IL (3) IL299326A (tr)
MX (2) MX2018002038A (tr)
PH (1) PH12018500371A1 (tr)
SG (1) SG10201913250SA (tr)
TW (2) TWI772270B (tr)
WO (1) WO2017031312A1 (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9993427B2 (en) * 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
IL273405B2 (en) 2014-12-30 2024-01-01 Cell Cure Neurosciences Ltd RPE cell populations and methods for their production
IL293110B2 (en) 2015-03-23 2023-11-01 Astellas Inst For Regenerative Medicine Improved assays for the potential of retinal pigment epithelium (RPE) cells and photoreceptor progenitors
TWI772270B (zh) 2015-08-18 2022-08-01 美商安斯泰來再生醫藥協會 臨床調配物
CA3028613A1 (en) * 2016-06-30 2018-01-04 Sumitomo Dainippon Pharma Co., Ltd. Transplantation medium
EP4000568A1 (en) * 2017-12-29 2022-05-25 Cell Cure Neurosciences Ltd. Retinal pigment epithelium cell compositions
CN115003794A (zh) 2019-08-28 2022-09-02 安斯泰来再生医药协会 治疗血管疾病的组合物和方法
TW202122577A (zh) 2019-08-28 2021-06-16 安斯泰來再生醫藥協會 治療血管疾病之方法
CN114981417A (zh) 2019-10-30 2022-08-30 安斯泰来再生医药协会 生产视网膜色素上皮细胞的方法
JP7018527B1 (ja) 2020-12-16 2022-02-10 アニコム先進医療研究所株式会社 細胞の保存方法および細胞懸濁液
WO2023288115A1 (en) * 2021-07-15 2023-01-19 Sio2 Medical Products, Inc. Preservative composition for nucleic acids and biological samples and methods of use
WO2023176906A1 (ja) * 2022-03-16 2023-09-21 住友ファーマ株式会社 移植用媒体
WO2024019962A1 (en) 2022-07-18 2024-01-25 Astellas Institute For Regenerative Medicine Methods of treating brain injury
WO2024044134A1 (en) 2022-08-23 2024-02-29 Astellas Institute For Regenerative Medicine Photoreceptor rescue cell (prc) compositions and methods for treatment of ocular disorders

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654266A (en) 1992-02-10 1997-08-05 Chen; Chung-Ho Composition for tissues to sustain viability and biological functions in surgery and storage
DE69227179D1 (de) * 1992-03-27 1998-11-05 Chen Chung Ho Mittel für Gewebe zur Erhaltung der Lebensfähigkeit und biologische Funktionen in der Chirurgie und Lagerung
DK0701455T3 (da) * 1993-06-04 2001-06-18 Biotime Inc Plasmalignende opløsning
IT1277707B1 (it) * 1995-12-22 1997-11-11 Chemedica Sa Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare
CN1152668C (zh) * 1997-08-22 2004-06-09 清水制药株式会社 含有葡萄糖的制剂
GB2336109A (en) 1998-04-07 1999-10-13 Univ Bristol Ophthalmic Irrigating Solution
KR100550023B1 (ko) 2000-01-11 2006-02-09 가부시키가이샤 오프테꾸스 눈 수술용 관류액 제제
US7084157B2 (en) 2002-05-17 2006-08-01 Rajeev Raut Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation
US20190282622A1 (en) 2004-01-23 2019-09-19 Astellas Institute For Regenerative Medicine Modalities for the treatment of degenerative diseases of the retina
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
WO2005070011A2 (en) 2004-01-23 2005-08-04 Advanced Cell Technology, Inc. Improved modalities for the treatment of degenerative diseases of the retina
KR20230145494A (ko) 2006-04-14 2023-10-17 아스텔라스 인스티튜트 포 리제너러티브 메디슨 혈관 콜로니 형성 세포
EP2617428A1 (en) * 2006-08-15 2013-07-24 Agency for Science, Technology and Research Mesenchymal stem cell conditioned medium
AU2008312007A1 (en) 2007-10-12 2009-04-23 Advanced Cell Technology, Inc. Improved methods of producing RPE cells and compositions of RPE cells
CA2722693C (en) 2008-05-06 2023-03-21 Advanced Cell Technology, Inc. Hemangio colony forming cells and non-engrafting hemangio cells
KR20210003301A (ko) 2008-05-06 2021-01-11 아스텔라스 인스티튜트 포 리제너러티브 메디슨 다능성 줄기세포로부터 유도된 탈핵 적혈구계 세포를 생산하는 방법
KR102073730B1 (ko) 2009-11-17 2020-02-05 아스텔라스 인스티튜트 포 리제너러티브 메디슨 인간 ｒｐｅ 세포의 생산 방법 및 인간 ｒｐｅ 세포의 제약 제제
JP6013187B2 (ja) 2009-12-04 2016-10-25 ステム セル アンド リジェネレイティブ メディスン インターナショナル， インコーポレイテッド ヒト胚性幹細胞由来血管芽細胞からナチュラルキラー細胞および樹状細胞を生成する方法
CA3115233A1 (en) 2009-12-04 2011-06-09 Astellas Institute For Regenerative Medicine Large scale generation of functional megakaryocytes and platelets from human embryonic stem cells under stromal-free conditions
US11739366B2 (en) 2010-07-23 2023-08-29 Astellas Institute For Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
CA2855941A1 (en) 2011-11-14 2013-05-23 Advanced Cell Technology, Inc. Pharmaceutical preparations of human rpe cells and uses thereof
CN108478599B (zh) 2011-11-30 2022-08-02 安斯泰来再生医药协会 间充质基质细胞及其相关用途
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
SI2788472T1 (sl) 2011-12-06 2019-04-30 Astellas Institute For Regenerative Medicine Način usmerjene diferencijacije, produciranja endotelijskih celic roženice
CN103783031B (zh) 2012-10-29 2015-11-18 四川新生命干细胞科技股份有限公司 一种细胞保存液
AU2013201546B2 (en) * 2012-12-18 2014-10-23 Gambro Lundia Ab Dialysis composition
CA3177929A1 (en) 2012-12-21 2014-06-26 Astellas Institute For Regenerative Medicine Methods for production of platelets from pluripotent stem cells and compositions thereof
US20160175362A1 (en) 2014-03-14 2016-06-23 Ocata Therapeutics, Inc. Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US20160175361A1 (en) 2014-03-14 2016-06-23 Advanced Cell Technology, Inc. Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
IL307568A (en) 2013-03-15 2023-12-01 Astellas Inst For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
CN107148276A (zh) 2014-09-05 2017-09-08 安斯泰来再生医药协会 视网膜神经节细胞及其祖细胞
IL293110B2 (en) 2015-03-23 2023-11-01 Astellas Inst For Regenerative Medicine Improved assays for the potential of retinal pigment epithelium (RPE) cells and photoreceptor progenitors
TWI772270B (zh) 2015-08-18 2022-08-01 美商安斯泰來再生醫藥協會 臨床調配物
CN115003794A (zh) 2019-08-28 2022-09-02 安斯泰来再生医药协会 治疗血管疾病的组合物和方法
TW202122577A (zh) 2019-08-28 2021-06-16 安斯泰來再生醫藥協會 治療血管疾病之方法
CN114981417A (zh) 2019-10-30 2022-08-30 安斯泰来再生医药协会 生产视网膜色素上皮细胞的方法

Also Published As

Publication number Publication date
WO2017031312A1 (en) 2017-02-23
US20210275673A1 (en) 2021-09-09
JP7043392B2 (ja) 2022-03-29
JP7449915B2 (ja) 2024-03-14
KR102651291B1 (ko) 2024-03-26
KR20230058544A (ko) 2023-05-03
HK1256839A1 (zh) 2019-10-04
IL299326A (en) 2023-02-01
IL291163A (en) 2022-05-01
KR102411018B1 (ko) 2022-06-20
CN108697641A (zh) 2018-10-23
KR20220090583A (ko) 2022-06-29
US11013808B2 (en) 2021-05-25
IL257551A (en) 2018-04-30
JP2024074803A (ja) 2024-05-31
EA037915B1 (ru) 2021-06-07
EA201890516A1 (ru) 2018-09-28
JP2022040140A (ja) 2022-03-10
JP2018523682A (ja) 2018-08-23
TWI772270B (zh) 2022-08-01
EA202190722A1 (ru) 2021-10-29
IL257551B (en) 2022-04-01
CA2995977A1 (en) 2017-02-23
MX2022010363A (es) 2022-09-21
AU2016308818A1 (en) 2018-04-05
US20190030168A1 (en) 2019-01-31
PH12018500371A1 (en) 2018-08-29
BR112018003031B1 (pt) 2023-12-26
IL291163B2 (en) 2023-05-01
BR112018003031A2 (pt) 2018-09-18
AU2016308818B2 (en) 2022-04-21
AU2022206757A1 (en) 2022-08-18
EP3334415A1 (en) 2018-06-20
NZ740608A (en) 2023-09-29
MX2018002038A (es) 2018-07-06
KR20180048722A (ko) 2018-05-10
TW202245816A (zh) 2022-12-01
IL291163B1 (en) 2023-01-01
TW201717912A (zh) 2017-06-01
TWI833293B (zh) 2024-02-21
US20190358330A9 (en) 2019-11-28
US11957754B2 (en) 2024-04-16

Similar Documents

Publication Publication Date Title
IL291163A (en) Clinical formulations
IL246978A0 (en) New paracetamol formulations
PT4070787T (pt) Formulações farmacêuticas
HK1254343A1 (zh) 藥物製劑
IL265609A (en) New formulations
GB201513010D0 (en) Novel formulation
GB201607918D0 (en) Novel formulations
GB201419261D0 (en) Formulations
GB201419091D0 (en) Formulations
ZA201707094B (en) Pharmaceutical formulations
GB2536793B (en) Endoscope
GB2556741B (en) Clinical thermometer
GB201417589D0 (en) Pharmaceutical Formulations
GB201805338D0 (en) Cosmetic formulations
GB201621277D0 (en) Formulations
GB201618110D0 (en) Formulations
GB201616366D0 (en) Formulations
GB201615754D0 (en) Formulations
GB201617866D0 (en) Novel formulations
GB201616509D0 (en) Novel formulations
GB201507784D0 (en) Formulations
GB201505532D0 (en) Formulations
GB201504482D0 (en) Novel formulations
GB201511580D0 (en) Clinical thermometer
GB201508527D0 (en) Novel formulation