SG10201912574WA - Calpain modulators and therapeutic uses thereof - Google Patents

Calpain modulators and therapeutic uses thereof

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Publication number
SG10201912574WA
SG10201912574WA SG10201912574WA SG10201912574WA SG10201912574WA SG 10201912574W A SG10201912574W A SG 10201912574WA SG 10201912574W A SG10201912574W A SG 10201912574WA SG 10201912574W A SG10201912574W A SG 10201912574WA SG 10201912574W A SG10201912574W A SG 10201912574WA
Authority
SG
Singapore
Prior art keywords
therapeutic uses
calpain modulators
calpain
modulators
therapeutic
Prior art date
Application number
SG10201912574WA
Other languages
English (en)
Inventor
Brad Buckman
John Nicholas
Shendong Yuan
Marc Adler
Kumaraswamy Emayan
Jingyuang Ma
Original Assignee
Blade Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blade Therapeutics Inc filed Critical Blade Therapeutics Inc
Publication of SG10201912574WA publication Critical patent/SG10201912574WA/en

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/42—Oxazoles
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