SG10201909629PA - Bioconjugates and uses thereof - Google Patents

Bioconjugates and uses thereof

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Publication number
SG10201909629PA
SG10201909629PA SG10201909629PA SG10201909629PA SG 10201909629P A SG10201909629P A SG 10201909629PA SG 10201909629P A SG10201909629P A SG 10201909629PA SG 10201909629P A SG10201909629P A SG 10201909629PA
Authority
SG
Singapore
Prior art keywords
binding unit
bioconjugates
peptide
bioconjugatesand
vcam
Prior art date
Application number
Other languages
English (en)
Inventor
Glenn Prestwich
John Paderi
Julia Chen
Ii Rush Bartlett
Original Assignee
Symic Ip Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symic Ip Llc filed Critical Symic Ip Llc
Publication of SG10201909629PA publication Critical patent/SG10201909629PA/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
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    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
SG10201909629P 2015-04-17 2016-04-15 Bioconjugates and uses thereof SG10201909629PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562149428P 2015-04-17 2015-04-17
US201562241057P 2015-10-13 2015-10-13
US201562244665P 2015-10-21 2015-10-21

Publications (1)

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SG10201909629PA true SG10201909629PA (en) 2019-11-28

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SG10201909629P SG10201909629PA (en) 2015-04-17 2016-04-15 Bioconjugates and uses thereof
SG11201708357QA SG11201708357QA (en) 2015-04-17 2016-04-15 Bioconjugates and uses thereof

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US (3) US20160331841A1 (pt)
EP (1) EP3283124B1 (pt)
JP (2) JP2018513879A (pt)
KR (1) KR20180016988A (pt)
CN (1) CN107771085A (pt)
AU (1) AU2016248341B2 (pt)
BR (1) BR112017021970A2 (pt)
CA (1) CA2982680A1 (pt)
EA (1) EA201792245A1 (pt)
HK (1) HK1251183A1 (pt)
IL (1) IL254977B (pt)
MA (1) MA44262A (pt)
MX (1) MX2017013196A (pt)
PH (1) PH12017501863A1 (pt)
SG (2) SG10201909629PA (pt)
TW (1) TW201718019A (pt)
WO (1) WO2016168743A1 (pt)

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AU2014233537A1 (en) 2013-03-15 2015-09-10 Symic Ip, Llc Extracellular matrix-binding synthetic peptidoglycans
CN105813661B (zh) 2013-12-10 2019-08-27 诺瓦普拉斯玛有限公司 用于操作植入物的容器、仪器和方法
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
MA39969A (fr) 2014-05-12 2015-11-19 Purdue Research Foundation Conjugués de ligands peptidiques se liant à icam/vcam et à la sélectine
EP3294351B1 (en) 2015-05-11 2022-03-23 Nova Plasma Ltd Method for preparing a silicone implant using plasma processing
JP6876217B2 (ja) * 2017-05-19 2021-05-26 二村 芳弘 抗炎症作用を呈するペプチドグリカン誘導体
KR20200026263A (ko) * 2017-07-07 2020-03-10 시믹 아이피, 엘엘씨 합성 생체접합체
US11896642B2 (en) 2017-07-07 2024-02-13 Symic Holdings, Inc. Bioconjugates with chemically modified backbones
WO2019035135A1 (en) 2017-08-16 2019-02-21 Nova Plasma Ltd. PLASMA PROCESSING OF AN IMPLANT
WO2019075213A1 (en) * 2017-10-11 2019-04-18 Northwestern University HEPARIN CONJUGATED TO PEPTIDES BINDING TO COLLAGEN FOR TARGETING BIOLOGICAL AND SYNTHETIC FABRICS
JP7457300B2 (ja) * 2018-08-29 2024-03-28 国立大学法人 岡山大学 神経変性疾患の診断用ペプチドマーカー
CN109106940B (zh) * 2018-09-17 2021-08-27 大连医科大学附属第一医院 Iellqar作为预防和治疗动脉粥样硬化疾病药物中的应用
CN110755597B (zh) * 2019-10-24 2023-07-07 广州市希丽生物科技服务有限公司 用于预防和治疗类风湿性关节炎的外用药物组合物
CN111701073A (zh) * 2020-06-01 2020-09-25 天津大学 一种基于胶原蛋白模拟肽改性透明质酸的关节注射制剂及其制备方法和应用

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