SG10201901708SA - Perfusion culturing methods and uses thereof - Google Patents

Perfusion culturing methods and uses thereof

Info

Publication number
SG10201901708SA
SG10201901708SA SG10201901708SA SG10201901708SA SG10201901708SA SG 10201901708S A SG10201901708S A SG 10201901708SA SG 10201901708S A SG10201901708S A SG 10201901708SA SG 10201901708S A SG10201901708S A SG 10201901708SA SG 10201901708S A SG10201901708S A SG 10201901708SA
Authority
SG
Singapore
Prior art keywords
degrees
culture medium
culturing
rpm
methods
Prior art date
Application number
SG10201901708SA
Other languages
English (en)
Inventor
Jianguo Yang
Agata Villiger-Oberbek
Yang Yang
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG10201901708SA publication Critical patent/SG10201901708SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/50—Means for positioning or orientating the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG10201901708SA 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof SG10201901708SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261717486P 2012-10-23 2012-10-23

Publications (1)

Publication Number Publication Date
SG10201901708SA true SG10201901708SA (en) 2019-03-28

Family

ID=49546634

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201901708SA SG10201901708SA (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof
SG11201503085VA SG11201503085VA (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201503085VA SG11201503085VA (en) 2012-10-23 2013-10-23 Perfusion culturing methods and uses thereof

Country Status (9)

Country Link
US (1) US20140154726A1 (fr)
EP (2) EP2912160B1 (fr)
CN (2) CN104903436B (fr)
AU (2) AU2013334602B2 (fr)
CA (1) CA2889022A1 (fr)
HK (1) HK1214292A1 (fr)
MX (2) MX363702B (fr)
SG (2) SG10201901708SA (fr)
WO (1) WO2014066519A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX367025B (es) * 2013-02-22 2019-08-02 Genzyme Corp Metodos de cultivo por perfusion con microportadores y usos de los mismos.
ES2717927T3 (es) 2013-02-22 2019-06-26 Genzyme Corp Procedimientos de cultivo por perfusión de microportadores y usos de los mismos
AR095196A1 (es) 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
TWI743024B (zh) * 2014-06-06 2021-10-21 美商健臻公司 灌注培養方法及其用途
TWI776235B (zh) 2014-06-09 2022-09-01 美商健臻公司 種子罐培養法(seed train processes)及其用途
HUE060385T2 (hu) 2014-10-24 2023-02-28 Genzyme Corp Fluidumáramok integrált folyamatos elszigetelése steril folyamatedényektõl
BR112017013423B1 (pt) 2014-12-22 2023-04-11 Genzyme Corporation Métodos para cultivo de célula de mamífero
CN105385731B (zh) * 2015-12-25 2018-10-30 上海莱士血液制品股份有限公司 一种表达重组八因子的灌注培养方法
KR20180047404A (ko) * 2016-10-31 2018-05-10 삼성바이오에피스 주식회사 세포 배양 배지에서 원치 않는 배양 부산물을 감소시키는 공정
EP3601584A1 (fr) * 2017-03-31 2020-02-05 Boehringer Ingelheim International GmbH Milieu de perfusion
MA50911A (fr) * 2017-11-13 2020-09-23 Amgen Inc Procédés de production de produits protéiniques

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866655B1 (fr) * 2004-02-20 2007-05-11 Cesco Bioengineering Co Ltd Appareil et procede pour la preparation et la mise en culture de cellules
WO2006138143A1 (fr) * 2005-06-15 2006-12-28 Amprotein Corporation Flacon pour culture en suspension
JP2008543307A (ja) * 2005-06-15 2008-12-04 アンプロテイン コーポレイション 懸濁培養用容器
US20080206819A1 (en) * 2006-08-21 2008-08-28 Mary Tsao Intensified Perfusion Production Method
WO2009034186A2 (fr) * 2007-09-13 2009-03-19 Helmholtz-Zentrum für Infektionsforschung GmbH Procédé de culture cellulaire
US20090233334A1 (en) * 2008-03-11 2009-09-17 Excellgene Sa Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale
US20100076380A1 (en) * 2008-06-16 2010-03-25 Amprotein Corporation Bioreactors
US8728479B2 (en) 2009-03-31 2014-05-20 The Trustees Of The University Of Pennsylvania Antigen-binding proteins comprising recombinant protein scaffolds

Also Published As

Publication number Publication date
CN108192822A (zh) 2018-06-22
HK1214292A1 (zh) 2016-07-22
EP3747984A1 (fr) 2020-12-09
MX363702B (es) 2019-03-29
EP2912160B1 (fr) 2020-07-29
AU2018222985A1 (en) 2018-09-20
CN104903436B (zh) 2018-03-30
CA2889022A1 (fr) 2014-05-01
US20140154726A1 (en) 2014-06-05
AU2013334602B2 (en) 2018-05-31
MX2019003638A (es) 2019-09-02
MX2015005206A (es) 2016-08-03
AU2013334602A1 (en) 2015-05-14
WO2014066519A1 (fr) 2014-05-01
EP2912160A1 (fr) 2015-09-02
CN104903436A (zh) 2015-09-09
SG11201503085VA (en) 2015-05-28

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