SG10201808690PA - Compositions and methods for producing elevated and sustained ketosis - Google Patents
Compositions and methods for producing elevated and sustained ketosisInfo
- Publication number
- SG10201808690PA SG10201808690PA SG10201808690PA SG10201808690PA SG10201808690PA SG 10201808690P A SG10201808690P A SG 10201808690PA SG 10201808690P A SG10201808690P A SG 10201808690PA SG 10201808690P A SG10201808690P A SG 10201808690PA SG 10201808690P A SG10201808690P A SG 10201808690PA
- Authority
- SG
- Singapore
- Prior art keywords
- ketosis
- blood
- compositions
- methods
- medium chain
- Prior art date
Links
- 208000007976 Ketosis Diseases 0.000 title abstract 5
- 230000004140 ketosis Effects 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000002459 sustained effect Effects 0.000 title abstract 2
- 239000008280 blood Substances 0.000 abstract 3
- 210000004369 blood Anatomy 0.000 abstract 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- 235000020805 dietary restrictions Nutrition 0.000 abstract 2
- 239000008103 glucose Substances 0.000 abstract 2
- 230000000977 initiatory effect Effects 0.000 abstract 2
- 150000002576 ketones Chemical class 0.000 abstract 2
- WHBMMWSBFZVSSR-UHFFFAOYSA-N 3-hydroxybutyric acid Chemical compound CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 239000000090 biomarker Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 235000020887 ketogenic diet Nutrition 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 150000004667 medium chain fatty acids Chemical class 0.000 abstract 1
- 229940057917 medium chain triglycerides Drugs 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 229940059579 mineral salts in combination Drugs 0.000 abstract 1
- 230000036314 physical performance Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
- 230000004580 weight loss Effects 0.000 abstract 1
- 208000016261 weight loss Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361803203P | 2013-03-19 | 2013-03-19 | |
| US201461926664P | 2014-01-13 | 2014-01-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201808690PA true SG10201808690PA (en) | 2018-11-29 |
Family
ID=51581503
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201506780RA SG11201506780RA (en) | 2013-03-19 | 2014-03-19 | Compositions and methods for producing elevated and sustained ketosis |
| SG10201808690PA SG10201808690PA (en) | 2013-03-19 | 2014-03-19 | Compositions and methods for producing elevated and sustained ketosis |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201506780RA SG11201506780RA (en) | 2013-03-19 | 2014-03-19 | Compositions and methods for producing elevated and sustained ketosis |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US9138420B2 (zh) |
| EP (1) | EP2976073B1 (zh) |
| JP (2) | JP6491189B2 (zh) |
| KR (2) | KR20150130312A (zh) |
| CN (1) | CN105050594B (zh) |
| AU (2) | AU2014236004B2 (zh) |
| BR (1) | BR112015024186B1 (zh) |
| CA (1) | CA2902603C (zh) |
| CL (2) | CL2015002802A1 (zh) |
| CR (1) | CR20150579A (zh) |
| HK (1) | HK1216847A1 (zh) |
| IL (2) | IL241316B (zh) |
| MX (2) | MX371259B (zh) |
| MY (1) | MY180761A (zh) |
| NZ (1) | NZ711433A (zh) |
| PE (1) | PE20151949A1 (zh) |
| PH (1) | PH12015501966A1 (zh) |
| RU (2) | RU2659386C2 (zh) |
| SG (2) | SG11201506780RA (zh) |
| WO (1) | WO2014153416A1 (zh) |
| ZA (1) | ZA201506387B (zh) |
Families Citing this family (112)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2670413T3 (es) | 2003-06-03 | 2018-05-30 | The United States Government As Represented By The Department Of Health And Human Services | Suplementos nutricionales y composiciones terapéuticas que comprenden derivados de (R)-3-hidroxibutirato |
| US8642654B2 (en) | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
| WO2014071389A1 (en) | 2012-11-05 | 2014-05-08 | Veech Richard L | Ketone bodies to protect tissues from damage by ionizing radiation |
| GB201304467D0 (en) | 2013-03-12 | 2013-04-24 | Tdeltas Ltd | Compound for use in protecting skin |
| CA2912518A1 (en) | 2013-03-14 | 2014-10-02 | University Of Florida Research Foundation, Incorporated | Regulation of cancer using natural compounds and/or diet |
| SG11201507685UA (en) | 2013-03-14 | 2015-10-29 | Isis Innovation | Process for producing (r)-3-hydroxybutyl (r)-3-hydroxybutyrate |
| GB201314127D0 (en) * | 2013-08-07 | 2013-09-18 | Tdeltas Ltd | Ketone body and ketone body ester for reducing muscle breakdown |
| CN107613989A (zh) | 2014-04-02 | 2018-01-19 | 南加利福尼亚大学 | 自身免疫病和多发性硬化症的治疗 |
| US11020372B2 (en) | 2015-03-24 | 2021-06-01 | University Of Florida Research Foundation, Incorporated | Dietary and natural product management of negative side effects of cancer treatment |
| WO2016210405A2 (en) * | 2015-06-26 | 2016-12-29 | University Of Florida Research Foundation, Incorporated | Method of treating inflammation using natural compounds and/or diet |
| US10987340B2 (en) | 2015-07-24 | 2021-04-27 | Jesse Alexander Galinski | Composition and method for rapidly inducing an endogenous ketosis |
| US10736861B2 (en) | 2016-03-11 | 2020-08-11 | Axcess Global Sciences, Llc | Mixed salt compositions for producing elevated and sustained ketosis |
| US10973786B2 (en) | 2016-03-11 | 2021-04-13 | Axcess Global Sciences, Llc | R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions |
| US10973792B2 (en) | 2019-02-13 | 2021-04-13 | Axcess Global Sciences, Llc | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use |
| US10292952B2 (en) * | 2016-03-11 | 2019-05-21 | Axcess Global Sciences, Llc | Mixed salt compositions for maintaining or restoring electrolyte balance while producing elevated and sustained ketosis |
| US10596131B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
| US10245242B1 (en) * | 2017-11-22 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
| US11103470B2 (en) | 2017-11-22 | 2021-08-31 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
| US11241403B2 (en) | 2016-03-11 | 2022-02-08 | Axcess Global Sciences, Llc | Beta-hydroxybutyrate mixed salt compositions and methods of use |
| US10596130B2 (en) | 2017-12-19 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
| US11185518B2 (en) | 2017-12-19 | 2021-11-30 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer |
| US10245243B1 (en) * | 2017-12-19 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
| US10596129B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
| US20170266147A1 (en) * | 2016-03-18 | 2017-09-21 | Csilla Ari D'Agostino | Methods of increasing latency of anesthetic induction using ketone supplementation |
| US20190091189A1 (en) * | 2016-03-21 | 2019-03-28 | Csilla Ari D'Agostino | Administration of exogenous ketone to lower blood glucose |
| AU2017238103A1 (en) * | 2016-03-21 | 2018-11-22 | University Of South Florida | Methods of improving motor function using ketone supplementation |
| US10376482B2 (en) | 2016-04-03 | 2019-08-13 | Franco Cavaleri | Butyrate and beta-hydroxybutyrate compositions |
| US12109182B2 (en) | 2016-04-19 | 2024-10-08 | Axcess Global Sciences, Llc | Administration of R-beta-hydroxybutyrate and related compounds in humans |
| CA3021784A1 (en) * | 2016-04-19 | 2017-10-26 | Keto Patent Group, Inc. | Administration of butyrate, beta-hydroxybutyrate, and related compounds in humans |
| US11026929B2 (en) | 2016-04-19 | 2021-06-08 | Keto Patent Group, Inc. | Administration of berberine metabolites |
| MX2018012800A (es) * | 2016-04-19 | 2019-09-04 | Keto Patent Group Inc | Administracion de metabolitos de berberina. |
| WO2017208217A2 (en) | 2016-06-01 | 2017-12-07 | Aspi Ip Holder Llc | C5 ketone compositions, and related methods, for therapeutic and performance supplementation |
| KR102638807B1 (ko) | 2016-06-07 | 2024-02-21 | 더 제이. 데이비드 글래드스톤 인스티튜트, 어 테스터멘터리 트러스트 이스타빌리쉬드 언더 더 윌 오브 제이. 데이비드 글래드스톤 | 베타-히드록시부티레이트 및 부탄디올의 중쇄 지방산 에스테르 및 이것을 사용하는 조성물 및 이것을 사용하는 방법 |
| US10588877B2 (en) | 2016-07-21 | 2020-03-17 | Savind, Inc. | Compositions comprising β-hydroxybutyric acid and salt, and methods of using the same |
| JP6935994B2 (ja) * | 2016-08-19 | 2021-09-15 | 株式会社明治 | ケトン体生成促進用組成物 |
| US20180057846A1 (en) * | 2016-08-30 | 2018-03-01 | KetoneAid Inc. | Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy |
| CA3036516A1 (en) | 2016-09-13 | 2018-03-22 | Abbott Laboratories | Ketogenic nutritional compositions |
| US10945975B2 (en) * | 2016-10-24 | 2021-03-16 | University Of South Florida | Delaying latency to seizure by combinations of ketone supplements |
| US20180177753A1 (en) * | 2016-12-23 | 2018-06-28 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for migraine symptom management |
| US9925164B1 (en) | 2017-01-12 | 2018-03-27 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for traumatic brain injury |
| US20180256103A1 (en) * | 2017-03-08 | 2018-09-13 | Abbott Diabetes Care Inc. | Systems, devices, and methods for wellness and nutrition monitoring and management using analyte data |
| EP3598897A4 (en) * | 2017-03-28 | 2021-01-13 | Lonza Solutions AG | WATER-SOLUBLE ANTIBACTERIAL COMPOSITION |
| JP6968624B2 (ja) * | 2017-04-06 | 2021-11-17 | 株式会社明治 | ケトン食摂取量の管理方法 |
| WO2018186481A1 (ja) * | 2017-04-06 | 2018-10-11 | 株式会社明治 | ケトン食の有効状態のモニタリング装置 |
| EP3609484A4 (en) * | 2017-04-12 | 2020-12-16 | Cavaleri, Franco | BUTYRATE AND BETA HYDROXYBUTYRATE COMPOSITIONS AND METHODS FOR THEIR USE |
| US20200129463A1 (en) * | 2018-10-29 | 2020-04-30 | Keto Patent Group, Inc. | Administration of butyrate, beta-hydroxybutyrate, cannabidiol, and related compounds in humans |
| CN107083406B (zh) * | 2017-05-27 | 2021-02-02 | 浙江华睿生物技术有限公司 | (r)-3-羟基丁酸的生产方法 |
| GB201710229D0 (en) | 2017-06-27 | 2017-08-09 | Tdeltas Ltd | Compounds for new use |
| KR20200029547A (ko) | 2017-07-21 | 2020-03-18 | 버크 인스티튜트 포 리서치 온 에이징 | 베타-히드록시부티레이트 및 부탄디올의 s-거울상이성질체 및 이의 사용 방법 |
| CN109394745A (zh) * | 2017-08-17 | 2019-03-01 | 博瑞生物医药（苏州）股份有限公司 | 一种包含左旋肉碱和β-羟基丁酸化合物的组合物 |
| US11760963B2 (en) | 2017-08-23 | 2023-09-19 | KetoneAid Inc. | Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol |
| GB201715654D0 (en) * | 2017-09-27 | 2017-11-08 | Tdeltas Ltd | Method of treatment |
| US20190119705A1 (en) * | 2017-10-20 | 2019-04-25 | KetoneAid Inc. | Substantially non-racemic ketone ester of beta hydroxybutyrate and production process thereof |
| US11202769B2 (en) | 2017-11-22 | 2021-12-21 | Axcess Global Sciences, Llc | Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function |
| US12090129B2 (en) | 2017-11-22 | 2024-09-17 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
| US10925843B2 (en) * | 2018-04-18 | 2021-02-23 | Axcess Global Sciences, Llc | Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate |
| US11596616B2 (en) | 2017-12-12 | 2023-03-07 | University Of South Florida | Compositions and methods for weight loss maintenance |
| US11944598B2 (en) | 2017-12-19 | 2024-04-02 | Axcess Global Sciences, Llc | Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer |
| AU2019205288A1 (en) * | 2018-01-05 | 2020-08-20 | Metabolic Technologies, Inc. | Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) assosiated with intermittent fasting |
| WO2019147503A1 (en) | 2018-01-25 | 2019-08-01 | Buck Institute For Research On Aging | Synthesis of 3-hydroxybutyryl 3-hydroxybutyrate and related compounds |
| MX2020007866A (es) * | 2018-02-01 | 2020-12-03 | Wellstat Therapeutics Corp | Composiciones y dispositivos para el suministro sistemico de uridina. |
| US10980772B2 (en) * | 2018-08-27 | 2021-04-20 | Axcess Global Sciences, Llc | Compositions and methods for delivering tetrahydrocannabinol and ketone bodies |
| US11129802B2 (en) | 2018-08-27 | 2021-09-28 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
| US11241401B2 (en) | 2020-02-06 | 2022-02-08 | Axcess Global Sciences, Llc | Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions |
| US11419836B2 (en) | 2019-02-13 | 2022-08-23 | Axcess Global Sciences, Llc | Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions |
| US11806324B2 (en) | 2018-04-18 | 2023-11-07 | Axcess Global Sciences, Llc | Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies |
| US20200061023A1 (en) * | 2018-08-27 | 2020-02-27 | Axcess Global Sciences, Llc | Compositions and methods for delivering tetrahydrocannabinol and ketone bodies |
| US10512615B1 (en) | 2018-08-27 | 2019-12-24 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
| US11484542B2 (en) | 2018-05-30 | 2022-11-01 | Adam Slank | Specialized tongue spray containing gymnemic acid and exogenous ketones |
| EP3801064B1 (en) * | 2018-06-07 | 2024-10-09 | Société des Produits Nestlé S.A. | Methods and compositions for increasing ketone bodies in animals |
| CA3022995C (en) * | 2018-06-12 | 2019-10-15 | Ketofibe (9211-3133 Quebec Inc.) | Novel ketogenic compounds, compositions, methods and use thereof |
| JP7410055B2 (ja) * | 2018-06-21 | 2024-01-09 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | ニコチンアミドアデニンジヌクレオチド（ｎａｄ＋）前駆体及び少なくとも１種のケトン又はケトン前駆体を使用する組成物及び方法 |
| EP3843716A4 (en) * | 2018-08-27 | 2022-06-01 | Exerkine Corporation | LYSOSOMAL DISEASE TREATMENT METHOD |
| US20200068939A1 (en) * | 2018-09-04 | 2020-03-05 | Jho Intellectual Property Holdings Llc | Nutritional compositions to increase and sustain blood ketone levels |
| WO2020068705A1 (en) | 2018-09-25 | 2020-04-02 | Ponce De Leon Health Designated Activity Company | Process of making calcium alpha-ketoglutarate |
| JP2022504250A (ja) * | 2018-10-05 | 2022-01-13 | アンパサンド バイオファーマシューティカルズ インコーポレイテッド | ケトンの経皮投与のための製剤および方法 |
| CN109480284A (zh) * | 2018-12-05 | 2019-03-19 | 上海欣海生物科技有限公司 | 一种生酮食品及其制备方法 |
| WO2020127182A1 (en) * | 2018-12-18 | 2020-06-25 | Société des Produits Nestlé S.A. | Mixed triglyceriges |
| CN109734575A (zh) * | 2019-01-04 | 2019-05-10 | 上海欣海国际贸易有限公司 | 一种制备3-羟基丁酸氨基酸盐复合物的方法 |
| CA3129751A1 (en) * | 2019-02-11 | 2020-08-20 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with s-enantiomer |
| CN113747890A (zh) * | 2019-02-11 | 2021-12-03 | 阿克塞斯全球科学有限责任公司 | 外消旋β-羟基丁酸盐混合盐-酸组合物和使用方法 |
| EP3923918A4 (en) * | 2019-02-11 | 2022-10-05 | Access Global Sciences, LLC | MIXED BETA HYDROXYBUTYRATE HCL ACID COMPOSITIONS AND METHODS OF USE |
| AU2020235643A1 (en) * | 2019-03-14 | 2021-09-30 | Augusta University Research Institute, Inc. | Methods and compositions for supporting renal health |
| JP7281927B2 (ja) * | 2019-03-14 | 2023-05-26 | 大阪瓦斯株式会社 | 心拍数低減剤 |
| US20220168256A1 (en) * | 2019-03-22 | 2022-06-02 | Societe Des Produits Nestle S.A | Methods using administration of medium chain triglycerides (mct) prior to a meal to increase ketone production from the mcts |
| WO2020193385A1 (en) | 2019-03-22 | 2020-10-01 | Société des Produits Nestlé S.A. | Methods using medium chain triglycerides administered prior to a meal to decrease postprandial glucose from the meal |
| CN114008014B (zh) * | 2019-06-12 | 2024-03-22 | 凯托利皮克斯治疗有限责任公司 | 用于生产酰基封端的3-羟基羧酸的多元醇基酯的方法 |
| EP3956282A1 (de) * | 2019-06-12 | 2022-02-23 | IOI Oleo GmbH | Verfahren zur herstellung von acylverkappten 3-hydroxycarbonsäuren sowie deren salzen und estern |
| US11950616B2 (en) | 2019-06-21 | 2024-04-09 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
| US11033553B2 (en) | 2019-06-21 | 2021-06-15 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
| US11915605B2 (en) | 2019-10-17 | 2024-02-27 | Nicolas Tzenios | Ketogenic diet recommendation to a user based on a blood low-density lipoprotein (LDL) level and a blood C-reactive protein level and/or a blood erythrocyte sedimentation rate (ESR) thereof |
| WO2021150928A1 (en) * | 2020-01-23 | 2021-07-29 | University Of South Florida | Prevention and treatment of effects of aging and age-associated disorders with ketone supplementation |
| CA3170624A1 (en) | 2020-03-05 | 2021-09-10 | VitaNav, Inc. | Composition of (d)-.beta.-hydroxybutyric acid, (d)-.beta.-hydroxyvalericacid, and (d)-1,3 butanediol as a nutritional supplement and therapeuticagent |
| CN116322687A (zh) * | 2020-06-14 | 2023-06-23 | L-纽乐股份有限公司 | 维持和延长禁食状态的间歇性禁食棒/饮料 |
| US20230255912A1 (en) * | 2020-07-02 | 2023-08-17 | Ponce De Leon Health Designated Activity Company | Compositions and methods for treating crp-mediated diseases |
| US20220062216A1 (en) * | 2020-08-26 | 2022-03-03 | Axcess Global Sciences, Llc | Compositions and methods for increasing lean-to-fat mass ratio |
| CN112137115A (zh) * | 2020-09-25 | 2020-12-29 | 深圳市捷利康生物科技有限公司 | 具有增强免疫力功效的生酮营养粉及其制备方法 |
| US20240180891A1 (en) * | 2020-12-22 | 2024-06-06 | Buck Institute For Research On Aging | Synergistic modulators of alpha-dicarbonyl detoxification and their use for inducing weight loss and the treatment of diabetic pathologies |
| WO2022217582A1 (en) * | 2021-04-16 | 2022-10-20 | Nanjing Nutrabuilding Bio-Tech Co., Ltd. | Low-lead and low-arsenic beta-hydroxybutyrate salts and methods for producing the same |
| WO2022232106A1 (en) * | 2021-04-26 | 2022-11-03 | University Of South Florida | Methods for treating symptoms of kabuki syndrome |
| RU2769242C1 (ru) * | 2021-06-16 | 2022-03-29 | Александр Владимирович Чемоданов | Кетогенная композиция |
| CA3223325A1 (en) | 2021-06-28 | 2023-01-05 | Roberto Vianna Nonato | Methods to produce therapeutic formulations comprising hydroxybutirate and hydroxyvalerate, therapeutic formulations and uses thereof |
| CN118541034A (zh) * | 2021-12-14 | 2024-08-23 | 三得利控股株式会社 | 碳酸饮料及增强碳酸饮料的碳酸感的方法 |
| AU2022417093A1 (en) * | 2021-12-14 | 2024-06-13 | Suntory Holdings Limited | Beverage containing 3-hydroxybutyric acid and lower aliphatic alcohol, and method for improving taste |
| CN114306308A (zh) * | 2021-12-24 | 2022-04-12 | 苏州麦轮生物科技有限公司 | 一种含有酮酯的营养补充剂及其应用 |
| US12023382B2 (en) | 2022-01-18 | 2024-07-02 | Today Inc. | Molecules, formulations, and methods for nutritional support of athletes, patients, and others |
| WO2023139357A1 (en) * | 2022-01-18 | 2023-07-27 | Today Inc. | Molecules, nutritional formulations, and methods of providing nutritional support |
| JP7223193B1 (ja) | 2022-05-26 | 2023-02-15 | 大阪瓦斯株式会社 | 内臓脂肪低減剤およびその用途 |
| CN115192603B (zh) * | 2022-07-06 | 2023-04-21 | 西北农林科技大学 | 锂盐在制备防治奶牛酮病制剂中的应用 |
| CN115251375A (zh) * | 2022-07-11 | 2022-11-01 | 珠海麦得发生物科技股份有限公司 | 一种(r)-3-羟基丁酸生酮产品及其制备方法 |
| US12059398B2 (en) | 2022-08-26 | 2024-08-13 | Health Via Modern Nutrition Inc. | Compositions of 1,3-butanediol and beta-hydroxybutyric acid to provide optimal therapeutic ketosis |
| US11969430B1 (en) | 2023-03-10 | 2024-04-30 | Axcess Global Sciences, Llc | Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8803141L (sv) * | 1988-09-07 | 1990-03-08 | Kabivitrum Ab | Naeringsmedel foer maenniskor och djur |
| US5654266A (en) * | 1992-02-10 | 1997-08-05 | Chen; Chung-Ho | Composition for tissues to sustain viability and biological functions in surgery and storage |
| US6323237B1 (en) | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
| DK1017379T3 (en) * | 1997-03-17 | 2015-02-16 | Btg Int Ltd | Therapeutic compositions comprising ketone compounds and precursors thereof |
| US6316038B1 (en) | 1997-03-17 | 2001-11-13 | Btg International Limited | Therapeutic compositions |
| US20090253781A1 (en) | 2002-05-24 | 2009-10-08 | Btg International Limited | Therapeutic compositions |
| JPH1160434A (ja) | 1997-08-12 | 1999-03-02 | Kanebo Ltd | 皮膚老化防止化粧料 |
| US6380244B2 (en) | 1998-07-22 | 2002-04-30 | Metabolix, Inc. | Nutritional and therapeutic uses of 3-hydroxyalkanoate oligomers |
| DK1123094T3 (da) | 1998-09-15 | 2007-08-20 | Btg Int Ltd | Terapeutiske præparater (II) |
| TWI249401B (en) * | 1999-04-14 | 2006-02-21 | Takeda Chemical Industries Ltd | Agent for improving ketosis |
| WO2001082928A1 (en) | 2000-05-01 | 2001-11-08 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
| US6613356B1 (en) | 2000-10-10 | 2003-09-02 | Victor Vlahakos | Weight loss medication and method |
| US20050129783A1 (en) * | 2001-04-19 | 2005-06-16 | Mccleary Edward L. | Composition and method for treatment of neurophysiological conditions and maintenance of neurophysiological health |
| US8158184B2 (en) * | 2004-03-08 | 2012-04-17 | Bunge Oils, Inc. | Structured lipid containing compositions and methods with health and nutrition promoting characteristics |
| GB0410266D0 (en) * | 2004-05-07 | 2004-06-09 | Ketocytonyx Inc | Treatment of apoptosis |
| GB0420856D0 (en) | 2004-09-20 | 2004-10-20 | Ketocytonyx Inc | Cns modulators |
| EP1915144A4 (en) * | 2005-06-20 | 2009-08-19 | Accera Inc | METHOD FOR REDUCING OXIDATIVE DAMAGE AND IMPROVING MITOCHONDRIA EFFICIENCY |
| ES2645816T3 (es) | 2006-04-03 | 2017-12-07 | Accera, Inc. | Uso de compuestos cetogénicos para el tratamiento de la alteración de la memoria asociada a la edad |
| US7807718B2 (en) | 2006-06-30 | 2010-10-05 | Sami A. Hashim | Glyceride esters for the treatment of diseases associated with reduced neuronal metabolism of glucose |
| RU2459624C2 (ru) * | 2007-04-12 | 2012-08-27 | Риджентс Оф Дзе Юниверсити Оф Миннесота | Защитные композиции от ишемии/реперфузии и способы применения |
| CN106038532B (zh) * | 2008-01-04 | 2019-05-14 | 牛津大学科技创新有限公司 | 用作降低血脂药剂的酮体和酮体酯 |
| GB201002983D0 (en) * | 2010-02-22 | 2010-04-07 | Tdeltas Ltd | Nutritinal composition |
| GB201206192D0 (en) | 2012-04-05 | 2012-05-23 | Tdeltas Ltd | Ketone bodies and ketone body esters and for maintaining or improving muscle power output |
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