SG10201603288XA - Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine - Google Patents
Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)CytosineInfo
- Publication number
- SG10201603288XA SG10201603288XA SG10201603288XA SG10201603288XA SG10201603288XA SG 10201603288X A SG10201603288X A SG 10201603288XA SG 10201603288X A SG10201603288X A SG 10201603288XA SG 10201603288X A SG10201603288X A SG 10201603288XA SG 10201603288X A SG10201603288X A SG 10201603288XA
- Authority
- SG
- Singapore
- Prior art keywords
- arabinofuranosyl
- deoxy
- cytosine
- thio
- fluoro
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/19—Purine radicals with arabinosyl as the saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012074525 | 2012-03-28 | ||
JP2013050846 | 2013-03-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201603288XA true SG10201603288XA (en) | 2016-05-30 |
Family
ID=49260082
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201406080VA SG11201406080VA (en) | 2012-03-28 | 2013-03-27 | SALT OF 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL)CYTOSINE |
SG10201603288XA SG10201603288XA (en) | 2012-03-28 | 2013-03-27 | Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201406080VA SG11201406080VA (en) | 2012-03-28 | 2013-03-27 | SALT OF 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL)CYTOSINE |
Country Status (19)
Country | Link |
---|---|
US (1) | US9896471B2 (ru) |
EP (1) | EP2832740B1 (ru) |
JP (1) | JP5833225B2 (ru) |
KR (2) | KR101770246B1 (ru) |
CN (1) | CN104203969B (ru) |
AU (1) | AU2013241341B2 (ru) |
BR (1) | BR112014020416B1 (ru) |
CA (2) | CA2865742C (ru) |
DK (1) | DK2832740T3 (ru) |
ES (1) | ES2730679T3 (ru) |
HK (1) | HK1201273A1 (ru) |
IL (1) | IL234222A (ru) |
MX (2) | MX352423B (ru) |
NZ (1) | NZ701245A (ru) |
PL (1) | PL2832740T3 (ru) |
RU (1) | RU2600734C2 (ru) |
SG (2) | SG11201406080VA (ru) |
TW (1) | TWI637963B (ru) |
WO (1) | WO2013146833A1 (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2013303534B2 (en) | 2012-08-13 | 2016-06-30 | Fujifilm Corporation | Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine, synthetic intermediate of thionucleoside, and method for producing the same |
WO2015125781A1 (ja) | 2014-02-18 | 2015-08-27 | 富士フイルム株式会社 | チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物 |
JP6204223B2 (ja) | 2014-02-19 | 2017-09-27 | 富士フイルム株式会社 | チオピラノース化合物等の製造方法 |
TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
JP6450356B2 (ja) * | 2016-02-29 | 2019-01-09 | 富士フイルム株式会社 | 液状医薬製剤 |
TWI787201B (zh) * | 2016-08-31 | 2022-12-21 | 日商富士軟片股份有限公司 | 抗腫瘤劑、抗腫瘤效果增強劑及抗腫瘤用套組 |
AU2018404329B2 (en) | 2018-01-29 | 2021-09-09 | Fujifilm Corporation | Antitumor agent for biliary tract cancer and method for treating biliary tract cancer |
TW202002989A (zh) * | 2018-03-13 | 2020-01-16 | 日商富士軟片股份有限公司 | 抗腫瘤劑、抗腫瘤效果增強劑及抗腫瘤用試劑盒 |
JP7520822B2 (ja) | 2018-09-25 | 2024-07-23 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 2’-ハロゲン化-4’-チオ-2’-デオキシ-5-アザシチジンアナログおよびその使用 |
KR102106096B1 (ko) | 2019-08-19 | 2020-04-29 | 이명준 | 경추 지압 마사지기 |
EP4378466A1 (en) | 2021-07-29 | 2024-06-05 | FUJIFILM Corporation | Pharmaceutical composition and anti-tumor agent for tumors that have at least either impaired bap1 or pbrm1 function |
KR102454186B1 (ko) | 2022-05-23 | 2022-10-14 | 이명준 | 경추 지압장치 |
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JP6204223B2 (ja) | 2014-02-19 | 2017-09-27 | 富士フイルム株式会社 | チオピラノース化合物等の製造方法 |
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2013
- 2013-03-27 DK DK13770090.2T patent/DK2832740T3/da active
- 2013-03-27 SG SG11201406080VA patent/SG11201406080VA/en unknown
- 2013-03-27 BR BR112014020416-0A patent/BR112014020416B1/pt active IP Right Grant
- 2013-03-27 SG SG10201603288XA patent/SG10201603288XA/en unknown
- 2013-03-27 MX MX2014011182A patent/MX352423B/es active IP Right Grant
- 2013-03-27 ES ES13770090T patent/ES2730679T3/es active Active
- 2013-03-27 RU RU2014143277/04A patent/RU2600734C2/ru active
- 2013-03-27 KR KR1020147030209A patent/KR101770246B1/ko active IP Right Grant
- 2013-03-27 TW TW102110915A patent/TWI637963B/zh active
- 2013-03-27 CN CN201380016308.9A patent/CN104203969B/zh active Active
- 2013-03-27 CA CA2865742A patent/CA2865742C/en active Active
- 2013-03-27 KR KR1020177018337A patent/KR20170082650A/ko not_active Application Discontinuation
- 2013-03-27 MX MX2017008865A patent/MX370733B/es unknown
- 2013-03-27 JP JP2014507938A patent/JP5833225B2/ja active Active
- 2013-03-27 EP EP13770090.2A patent/EP2832740B1/en active Active
- 2013-03-27 NZ NZ701245A patent/NZ701245A/en unknown
- 2013-03-27 WO PCT/JP2013/058896 patent/WO2013146833A1/ja active Application Filing
- 2013-03-27 AU AU2013241341A patent/AU2013241341B2/en active Active
- 2013-03-27 CA CA2943998A patent/CA2943998C/en active Active
- 2013-03-27 PL PL13770090T patent/PL2832740T3/pl unknown
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2014
- 2014-08-21 IL IL234222A patent/IL234222A/en active IP Right Grant
- 2014-09-26 US US14/498,334 patent/US9896471B2/en active Active
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2015
- 2015-02-17 HK HK15101764.5A patent/HK1201273A1/zh unknown
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