SE9501567D0 - A new combination - Google Patents
A new combinationInfo
- Publication number
- SE9501567D0 SE9501567D0 SE9501567A SE9501567A SE9501567D0 SE 9501567 D0 SE9501567 D0 SE 9501567D0 SE 9501567 A SE9501567 A SE 9501567A SE 9501567 A SE9501567 A SE 9501567A SE 9501567 D0 SE9501567 D0 SE 9501567D0
- Authority
- SE
- Sweden
- Prior art keywords
- composition
- component
- disorders
- new combination
- phthalancarbonitrile
- Prior art date
Links
- 239000000203 mixture Substances 0.000 abstract 5
- 208000019022 Mood disease Diseases 0.000 abstract 2
- WSEQXVZVJXJVFP-UHFFFAOYSA-N 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Chemical compound O1CC2=CC(C#N)=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 WSEQXVZVJXJVFP-UHFFFAOYSA-N 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- -1 hydrogen (2R,3R)-tartrate Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Priority Applications (36)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9501567A SE9501567D0 (sv) | 1995-04-27 | 1995-04-27 | A new combination |
ZA962982A ZA962982B (en) | 1995-04-27 | 1996-04-15 | A new combination |
TW085104481A TW458777B (en) | 1995-04-27 | 1996-04-15 | Pharmaceutical compositions for treating affective disorders |
IL11798896A IL117988A0 (en) | 1995-04-27 | 1996-04-21 | A new combination of an inhibitor and an antagonist |
SI9630486T SI0822813T1 (en) | 1995-04-27 | 1996-04-23 | A combination of a 5-ht uptake inhibitor with a selective 5-ht 1a antagonist |
CA002218181A CA2218181A1 (en) | 1995-04-27 | 1996-04-23 | A combination of a 5-ht uptake inhibitor with a selective 5-ht1a antagonist |
CN96194810A CN1102386C (zh) | 1995-04-27 | 1996-04-23 | 5-ht摄取抑制剂与选择性5-ht1a拮抗剂的组合物 |
EE9700245A EE03553B1 (et) | 1995-04-27 | 1996-04-23 | 5-HT tagasihaarde inhibiitori kombinatsioon selektiivse 5-HT1A antagonistiga |
DK96912370T DK0822813T3 (da) | 1995-04-27 | 1996-04-23 | Kombination af en 5-HT-optagelsesinhibitor med en selektiv 5-HT 1A-antagonist |
RU97119427/14A RU2183955C2 (ru) | 1995-04-27 | 1996-04-23 | Сочетание ингибитора усвоения 5-нт с селективным 5-нт1a антагонистом |
EP96912370A EP0822813B1 (en) | 1995-04-27 | 1996-04-23 | A combination of a 5-ht uptake inhibitor with a selective 5-ht 1a antagonist |
AT96912370T ATE216579T1 (de) | 1995-04-27 | 1996-04-23 | Kombination eines 5-ht uptakeinibitors mit einem selektiven 5-ht 1a antagonisten |
HK98101990.1A HK1002853B (en) | 1995-04-27 | 1996-04-23 | A combination of a 5-ht uptake inhibitor with a selective 5-ht1a antagonist |
DE69620878T DE69620878T2 (de) | 1995-04-27 | 1996-04-23 | Kombination eines 5-ht uptakeinibitors mit einem selektiven 5-ht 1a antagonisten |
HU9801946A HUP9801946A3 (en) | 1995-04-27 | 1996-04-23 | A combination al medicament containing a 5-ht uptake inhibitor and a selective 5-ht1a antagonist and process for producing it |
BR9608252A BR9608252A (pt) | 1995-04-27 | 1996-04-23 | Combinação de um primeiro componente que é um inibidor de reabsorção de 5-ht e um segundo componente que é antagonista de 5-th uso da combinação processos para o tratamento de disúrbios efetivos e da depressão para a preparaç o da combinaç o e para melhoria do início de ação terapéutica formulação farmacéutica para o suo no tratamento de distúrbios efetivos e kit |
SK1429-97A SK282060B6 (sk) | 1995-04-27 | 1996-04-23 | Kombinácia inhibítora spätnej absorpcie 5-ht so selektívnou protilátkou 5-ht1a, spôsob jej prípravy, farmaceutická formulácia s jej obsahom, jej použitie a kit s jej obsahom |
AU55202/96A AU696356C (en) | 1995-04-27 | 1996-04-23 | A combination of a 5-HT uptake inhibitor with a selective 5-HT1A antagonist |
PL96323083A PL183997B1 (pl) | 1995-04-27 | 1996-04-23 | Środek farmaceutyczny oraz zastosowanie połączenia inhibitora wychwytu zwrotnego 5-HT i selektywnego antagonisty 5-HT |
NZ306602A NZ306602A (en) | 1995-04-27 | 1996-04-23 | A fast onset combination of a 5-ht-reuptake inhibitor and a selective 5-ht1a antagonist in its r-enantiomer form such as 5-carbamoyl-8-fluoro-3,4-dihydro-2h-1-benzopyran derivative |
PT96912370T PT822813E (pt) | 1995-04-27 | 1996-04-23 | Combinacao de um inibidor da absorcao de 5-ht com um antagonista de 5-ht1a selectivo |
KR1019970707592A KR100419810B1 (ko) | 1995-04-27 | 1996-04-23 | 5-ht흡수억제제와선택성5-ht1a길항제의조합물 |
JP8532425A JPH11504037A (ja) | 1995-04-27 | 1996-04-23 | 5−ht取り込み阻害薬と選択的5−ht▲下1a▼アンタゴニストとの組み合わせ |
TR97/01254T TR199701254T1 (xx) | 1995-04-27 | 1996-04-23 | 5-HT al�� inhibit�r�n�n selektif 5-HT1A antagonistiyle kombinasyonu. |
CZ973356A CZ335697A3 (cs) | 1995-04-27 | 1996-04-23 | Směs 5-HT inhibitoru se selektivním 5-HT 1A antagonistem a farmaceutický prostředek, který je obsahuje |
US08/640,896 US5962514A (en) | 1995-04-27 | 1996-04-23 | Combination of 5-HT uptake inhibitor with a selective 5-HT1A antagonist |
ES96912370T ES2175089T3 (es) | 1995-04-27 | 1996-04-23 | Una combinacion de un inhibidor de la absorcion de 5 - ht con un ant agonista selectivo de 5 ht1a. |
PCT/SE1996/000526 WO1996033710A1 (en) | 1995-04-27 | 1996-04-23 | A combination of a 5-ht uptake inhibitor with a selective 5-ht1a antagonist |
ARP960102323A AR002990A1 (es) | 1995-04-27 | 1996-04-25 | Una nueva combinacion de un inhibidor de reabsorcion de 5-ht y un antagonista 5-ht(1a), su uso para la preparacion de medicamentos, una formulacion farmaceutica que la comprende, un procedimiento para la preparacion de dicha combinacion y equipo que contiene dicha combinacion. |
YU25696A YU25696A (sh) | 1995-04-27 | 1996-04-26 | Postupak dobijanja kombinacije (r)-5-karbamoil-8-fluoro-3- n,n-disupstituisan-amino-3,4-dihloro-2h-1-bezopirana i farmaceutske formulacije koje ih sadrže |
IS4585A IS1821B (is) | 1995-04-27 | 1997-10-09 | Samsetning 5-HT upptöku-hemils og valkvæðs 5-HT 1A -mótlyfs |
NO19974921A NO317057B1 (no) | 1995-04-27 | 1997-10-24 | Kombinasjon av en 5-HT-opptaksinhibitor med en selektiv 5-HT<N>1A</N> antagonist, formulering og kit inneholdende en slik kombinasjon, fremgangsmate for dens fremstilling, og anvendelse derav. |
US09/349,590 US6184218B1 (en) | 1995-04-27 | 1999-07-09 | Composition and methods employing it for the treatment of 5-HT-mediated disorders |
US09/351,071 US6184219B1 (en) | 1995-04-27 | 1999-07-09 | Composition and methods employing it for the treatment of 5-HT-mediated disorders |
US09/351,070 US6172105B1 (en) | 1995-04-27 | 1999-07-09 | Composition and methods employing it for the treatment of 5-HT-mediated disorders |
US09/351,069 US6169098B1 (en) | 1995-04-27 | 1999-07-09 | Composition and methods employing it for the treatment of 5-HT-mediated disorders |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9501567A SE9501567D0 (sv) | 1995-04-27 | 1995-04-27 | A new combination |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9501567D0 true SE9501567D0 (sv) | 1995-04-27 |
Family
ID=20398119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9501567A SE9501567D0 (sv) | 1995-04-27 | 1995-04-27 | A new combination |
Country Status (29)
Country | Link |
---|---|
US (5) | US5962514A (cs) |
EP (1) | EP0822813B1 (cs) |
JP (1) | JPH11504037A (cs) |
KR (1) | KR100419810B1 (cs) |
CN (1) | CN1102386C (cs) |
AR (1) | AR002990A1 (cs) |
AT (1) | ATE216579T1 (cs) |
BR (1) | BR9608252A (cs) |
CA (1) | CA2218181A1 (cs) |
CZ (1) | CZ335697A3 (cs) |
DE (1) | DE69620878T2 (cs) |
DK (1) | DK0822813T3 (cs) |
EE (1) | EE03553B1 (cs) |
ES (1) | ES2175089T3 (cs) |
HU (1) | HUP9801946A3 (cs) |
IL (1) | IL117988A0 (cs) |
IS (1) | IS1821B (cs) |
NO (1) | NO317057B1 (cs) |
NZ (1) | NZ306602A (cs) |
PL (1) | PL183997B1 (cs) |
PT (1) | PT822813E (cs) |
RU (1) | RU2183955C2 (cs) |
SE (1) | SE9501567D0 (cs) |
SK (1) | SK282060B6 (cs) |
TR (1) | TR199701254T1 (cs) |
TW (1) | TW458777B (cs) |
WO (1) | WO1996033710A1 (cs) |
YU (1) | YU25696A (cs) |
ZA (1) | ZA962982B (cs) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
SE9703374D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | A new combination |
AU4100699A (en) * | 1998-05-28 | 1999-12-13 | Sepracor, Inc. | Compositions and methods employing r(-) fluoxetine and other active ingredients |
SE9803155D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
SE9803157D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
SE9803158D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
SE9803156D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
AR021155A1 (es) * | 1999-07-08 | 2002-06-12 | Lundbeck & Co As H | Tratamiento de desordenes neuroticos |
UA77650C2 (en) * | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
US6331233B1 (en) | 2000-02-02 | 2001-12-18 | Honeywell International Inc. | Tantalum sputtering target with fine grains and uniform texture and method of manufacture |
PT1358177E (pt) | 2000-10-13 | 2006-09-29 | Neurosearch As | Tratamento de desordens afectivas atraves da accao combinada de um agonista do receptor nicotinico e uma substancia manoaminergica |
US20030185754A1 (en) * | 2001-01-16 | 2003-10-02 | Genset, S.A. | Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists |
US20030166554A1 (en) * | 2001-01-16 | 2003-09-04 | Genset, S.A. | Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists |
SK14612003A3 (sk) * | 2001-05-01 | 2004-04-06 | H. Lundbeck A/S | Použitie enantiomérne čistého escitalopramu a farmaceutický prostriedok s obsahom escitalopramu |
US7034059B2 (en) | 2001-07-02 | 2006-04-25 | Sepracor Inc. | Methods of using norfluoxetine |
US6855735B2 (en) | 2002-03-20 | 2005-02-15 | Temple University Of The Commonwealth System Of Higher Education | Ketamine treatment of restless legs syndrome |
KR20050040921A (ko) * | 2002-08-15 | 2005-05-03 | 와이어쓰 | 체온조절 기능장애 치료를 위한 5HT2a 수용체의 항진제 |
US20050032873A1 (en) * | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
US7695601B2 (en) * | 2006-05-09 | 2010-04-13 | The United States Of America As Represented By The Secretary Of The Army | Electrochemical test apparatus and method for its use |
US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
US20160154928A1 (en) * | 2013-07-12 | 2016-06-02 | Immuneering Corporation | Systems, methods, and environment for automated review of genomic data to identify downregulated and/or upregulated gene expression indicative of a disease or condition |
CN110546136B (zh) | 2017-02-14 | 2023-07-18 | 研究三角协会 | 基于脯氨酸的神经肽ff受体调节剂 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4698342A (en) * | 1985-07-16 | 1987-10-06 | Serotonin Industries Of Charleston | Method and compositions for controlling pain, depression and sedation |
US5616610A (en) * | 1989-12-22 | 1997-04-01 | Astra Aktiebolag | (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans |
US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
-
1995
- 1995-04-27 SE SE9501567A patent/SE9501567D0/xx unknown
-
1996
- 1996-04-15 ZA ZA962982A patent/ZA962982B/xx unknown
- 1996-04-15 TW TW085104481A patent/TW458777B/zh not_active IP Right Cessation
- 1996-04-21 IL IL11798896A patent/IL117988A0/xx not_active IP Right Cessation
- 1996-04-23 CN CN96194810A patent/CN1102386C/zh not_active Expired - Fee Related
- 1996-04-23 ES ES96912370T patent/ES2175089T3/es not_active Expired - Lifetime
- 1996-04-23 CZ CZ973356A patent/CZ335697A3/cs unknown
- 1996-04-23 JP JP8532425A patent/JPH11504037A/ja not_active Ceased
- 1996-04-23 WO PCT/SE1996/000526 patent/WO1996033710A1/en active IP Right Grant
- 1996-04-23 EP EP96912370A patent/EP0822813B1/en not_active Expired - Lifetime
- 1996-04-23 SK SK1429-97A patent/SK282060B6/sk unknown
- 1996-04-23 KR KR1019970707592A patent/KR100419810B1/ko not_active Expired - Fee Related
- 1996-04-23 AT AT96912370T patent/ATE216579T1/de not_active IP Right Cessation
- 1996-04-23 DK DK96912370T patent/DK0822813T3/da active
- 1996-04-23 TR TR97/01254T patent/TR199701254T1/xx unknown
- 1996-04-23 CA CA002218181A patent/CA2218181A1/en not_active Abandoned
- 1996-04-23 RU RU97119427/14A patent/RU2183955C2/ru active
- 1996-04-23 BR BR9608252A patent/BR9608252A/pt not_active Application Discontinuation
- 1996-04-23 DE DE69620878T patent/DE69620878T2/de not_active Expired - Fee Related
- 1996-04-23 PT PT96912370T patent/PT822813E/pt unknown
- 1996-04-23 NZ NZ306602A patent/NZ306602A/en unknown
- 1996-04-23 HU HU9801946A patent/HUP9801946A3/hu unknown
- 1996-04-23 PL PL96323083A patent/PL183997B1/pl unknown
- 1996-04-23 EE EE9700245A patent/EE03553B1/xx not_active IP Right Cessation
- 1996-04-23 US US08/640,896 patent/US5962514A/en not_active Expired - Fee Related
- 1996-04-25 AR ARP960102323A patent/AR002990A1/es not_active Application Discontinuation
- 1996-04-26 YU YU25696A patent/YU25696A/sh unknown
-
1997
- 1997-10-09 IS IS4585A patent/IS1821B/is unknown
- 1997-10-24 NO NO19974921A patent/NO317057B1/no unknown
-
1999
- 1999-07-09 US US09/351,071 patent/US6184219B1/en not_active Expired - Fee Related
- 1999-07-09 US US09/351,069 patent/US6169098B1/en not_active Expired - Fee Related
- 1999-07-09 US US09/349,590 patent/US6184218B1/en not_active Expired - Fee Related
- 1999-07-09 US US09/351,070 patent/US6172105B1/en not_active Expired - Fee Related
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