ATE276231T1 - Nitroxyderivate von (r) und (s)-carnitin - Google Patents
Nitroxyderivate von (r) und (s)-carnitinInfo
- Publication number
- ATE276231T1 ATE276231T1 AT00951861T AT00951861T ATE276231T1 AT E276231 T1 ATE276231 T1 AT E276231T1 AT 00951861 T AT00951861 T AT 00951861T AT 00951861 T AT00951861 T AT 00951861T AT E276231 T1 ATE276231 T1 AT E276231T1
- Authority
- AT
- Austria
- Prior art keywords
- carnitine
- derivatives
- formula
- nitroxy derivatives
- nitroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999RM000508A IT1306184B1 (it) | 1999-08-05 | 1999-08-05 | Nitrilossi derivati della (r) e (s)-carnitina. |
PCT/IT2000/000325 WO2001010819A1 (en) | 1999-08-05 | 2000-07-31 | Nitroxy derivatives of (r) and (s)-carnitine |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE276231T1 true ATE276231T1 (de) | 2004-10-15 |
Family
ID=11406927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00951861T ATE276231T1 (de) | 1999-08-05 | 2000-07-31 | Nitroxyderivate von (r) und (s)-carnitin |
Country Status (16)
Country | Link |
---|---|
US (2) | US6395923B2 (de) |
EP (1) | EP1224161B1 (de) |
JP (1) | JP2003506429A (de) |
KR (1) | KR100772205B1 (de) |
AT (1) | ATE276231T1 (de) |
AU (1) | AU6470400A (de) |
CA (1) | CA2379047A1 (de) |
CZ (1) | CZ20025A3 (de) |
DE (1) | DE60013876T2 (de) |
DK (1) | DK1224161T3 (de) |
ES (1) | ES2226896T3 (de) |
HU (1) | HUP0203034A3 (de) |
IT (1) | IT1306184B1 (de) |
PT (1) | PT1224161E (de) |
SK (1) | SK287134B6 (de) |
WO (1) | WO2001010819A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITRM20010456A1 (it) * | 2001-07-26 | 2003-01-27 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di (r)- o (s)- amminocarnitina sale interno, dei suoi sali e dei suoi derivati. |
AU2019247903A1 (en) | 2018-04-06 | 2020-10-22 | Amo Development, Llc | Methods and systems for changing a refractive property of an implantable intraocular lens |
EP3855944A4 (de) * | 2018-10-29 | 2022-06-29 | Lonza Consumer Health Inc. | Verfahren und zusammensetzung zur erhöhung der bioverfügbarkeit von carnitin |
US10703707B2 (en) | 2018-11-07 | 2020-07-07 | Industrial Technology Research Institute | Method for preparing nitrate ester |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3830931A (en) * | 1972-11-06 | 1974-08-20 | Felice S De | Carnitine and its use in the treatment of arrhythmia and impaired cardiac function |
US5214166A (en) * | 1986-11-29 | 1993-05-25 | The United States Of America As Represented By The Secretary Of The Navy | Method of synthesizing nitrato alkyl oxetanes |
CH679856A5 (de) * | 1990-07-04 | 1992-04-30 | Lonza Ag | |
IT1256705B (it) * | 1992-12-21 | 1995-12-12 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
IT1261231B (it) * | 1993-04-08 | 1996-05-09 | Sigma Tau Ind Farmaceuti | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
IT1261489B (it) * | 1993-07-29 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r amminocarnitina e s amminocarnitina. |
TR199903054T2 (xx) * | 1997-06-11 | 2000-07-21 | Isis Pharma Gmbh | Yeni pentaerythrit t�revleri, bunlar�n imalat� ve kullan�mlar� ile bunlar�n sentezi i�in ara maddeler. |
-
1999
- 1999-08-05 IT IT1999RM000508A patent/IT1306184B1/it active
-
2000
- 2000-07-31 ES ES00951861T patent/ES2226896T3/es not_active Expired - Lifetime
- 2000-07-31 KR KR1020027001592A patent/KR100772205B1/ko not_active IP Right Cessation
- 2000-07-31 JP JP2001515286A patent/JP2003506429A/ja active Pending
- 2000-07-31 DE DE60013876T patent/DE60013876T2/de not_active Expired - Lifetime
- 2000-07-31 HU HU0203034A patent/HUP0203034A3/hu unknown
- 2000-07-31 DK DK00951861T patent/DK1224161T3/da active
- 2000-07-31 CA CA002379047A patent/CA2379047A1/en not_active Abandoned
- 2000-07-31 EP EP00951861A patent/EP1224161B1/de not_active Expired - Lifetime
- 2000-07-31 PT PT00951861T patent/PT1224161E/pt unknown
- 2000-07-31 AT AT00951861T patent/ATE276231T1/de not_active IP Right Cessation
- 2000-07-31 CZ CZ20025A patent/CZ20025A3/cs unknown
- 2000-07-31 AU AU64704/00A patent/AU6470400A/en not_active Abandoned
- 2000-07-31 SK SK175-2002A patent/SK287134B6/sk not_active IP Right Cessation
- 2000-07-31 WO PCT/IT2000/000325 patent/WO2001010819A1/en active IP Right Grant
-
2001
- 2001-03-13 US US09/804,270 patent/US6395923B2/en not_active Expired - Fee Related
-
2002
- 2002-04-11 US US10/119,954 patent/US6548693B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE60013876T2 (de) | 2005-09-29 |
HUP0203034A3 (en) | 2003-11-28 |
PL358333A1 (en) | 2004-08-09 |
PT1224161E (pt) | 2005-01-31 |
US6548693B2 (en) | 2003-04-15 |
ITRM990508A1 (it) | 2001-02-05 |
AU6470400A (en) | 2001-03-05 |
US20020119965A1 (en) | 2002-08-29 |
ITRM990508A0 (it) | 1999-08-05 |
KR20020025213A (ko) | 2002-04-03 |
EP1224161B1 (de) | 2004-09-15 |
EP1224161A1 (de) | 2002-07-24 |
SK1752002A3 (en) | 2002-06-04 |
SK287134B6 (sk) | 2010-01-07 |
ES2226896T3 (es) | 2005-04-01 |
DE60013876D1 (de) | 2004-10-21 |
CA2379047A1 (en) | 2001-02-15 |
DK1224161T3 (da) | 2005-01-24 |
US20010011074A1 (en) | 2001-08-02 |
JP2003506429A (ja) | 2003-02-18 |
CZ20025A3 (cs) | 2002-07-17 |
US6395923B2 (en) | 2002-05-28 |
WO2001010819A1 (en) | 2001-02-15 |
HUP0203034A2 (hu) | 2003-02-28 |
IT1306184B1 (it) | 2001-05-30 |
KR100772205B1 (ko) | 2007-11-01 |
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