SE8201694L - Forfarande for framstellning av osymmetriskt 1,3-disubstituerade nitrosourinemnen - Google Patents

Forfarande for framstellning av osymmetriskt 1,3-disubstituerade nitrosourinemnen

Info

Publication number
SE8201694L
SE8201694L SE8201694A SE8201694A SE8201694L SE 8201694 L SE8201694 L SE 8201694L SE 8201694 A SE8201694 A SE 8201694A SE 8201694 A SE8201694 A SE 8201694A SE 8201694 L SE8201694 L SE 8201694L
Authority
SE
Sweden
Prior art keywords
disubstituted
nitrosour
asymmetric
substances
preparing
Prior art date
Application number
SE8201694A
Other languages
English (en)
Other versions
SE453081B (sv
Inventor
G Eisenbrand
Original Assignee
Deutsches Krebsforsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch
Publication of SE8201694L publication Critical patent/SE8201694L/sv
Publication of SE453081B publication Critical patent/SE453081B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Claims (1)

PATENTKRAV
1. Fdrfarande fOr framstallning av en N-osubstituerad alkyl-N-nitrosokarbamoylazid oiler N-substituerad alkyl-Nnitrosokarbamoylazid, kannetecknat av Ott en N-osubstituerad alkylkarbamoylazid eller N-substituerad alkylkarbamoylazid omsatts med kvavetetroxid i kyla i ett ldsningsmedel, corn under reaktionsbetingelserna ar inert mot reaktanterna.
SE8201694A 1976-05-25 1982-03-17 Nya n-halogenalkyl-n-nitroso-karbamoylazider som utgangsmaterial for framstellning av kemoterapeutiskt aktiva osymmetriskt 1,3-disubstituerade nitrosourinemnen SE453081B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2623420A DE2623420C2 (de) 1976-05-25 1976-05-25 Verfahren zur Herstellung unsymmetrisch 13-disubstituierter Nitrosoharnstoffe

Publications (2)

Publication Number Publication Date
SE8201694L true SE8201694L (sv) 1982-03-17
SE453081B SE453081B (sv) 1988-01-11

Family

ID=5978961

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7706074A SE434152B (sv) 1976-05-25 1977-05-24 Forfarande for framstellning av osymmetriskt 1,3-disubstituerade nitrosourinemnen
SE8201694A SE453081B (sv) 1976-05-25 1982-03-17 Nya n-halogenalkyl-n-nitroso-karbamoylazider som utgangsmaterial for framstellning av kemoterapeutiskt aktiva osymmetriskt 1,3-disubstituerade nitrosourinemnen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7706074A SE434152B (sv) 1976-05-25 1977-05-24 Forfarande for framstellning av osymmetriskt 1,3-disubstituerade nitrosourinemnen

Country Status (27)

Country Link
US (2) US4150146A (sv)
JP (2) JPS535118A (sv)
AT (1) AT360551B (sv)
AU (1) AU525278B2 (sv)
BE (1) BE855043A (sv)
CA (1) CA1092143A (sv)
CH (1) CH639947A5 (sv)
DD (1) DD130035A5 (sv)
DE (1) DE2623420C2 (sv)
DK (1) DK165786C (sv)
ES (1) ES459137A1 (sv)
FI (1) FI771665A (sv)
FR (2) FR2361357A1 (sv)
GB (2) GB1585822A (sv)
HK (2) HK28782A (sv)
HU (2) HU176768B (sv)
IE (1) IE45286B1 (sv)
IL (1) IL52142A (sv)
IT (1) IT1085808B (sv)
LU (1) LU77389A1 (sv)
MC (1) MC1142A1 (sv)
NL (1) NL187066C (sv)
NO (2) NO151410C (sv)
SE (2) SE434152B (sv)
SU (2) SU963464A3 (sv)
YU (2) YU40901B (sv)
ZA (2) ZA773144B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2623420C2 (de) * 1976-05-25 1978-07-06 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Verfahren zur Herstellung unsymmetrisch 13-disubstituierter Nitrosoharnstoffe
DE2845574A1 (de) 1978-10-19 1980-04-24 Deutsches Krebsforsch Durch heterocyclische ringe oder alkylreste substituierte analoga von ccnu und verfahren zu deren herstellung
JPS57116043A (en) * 1981-01-12 1982-07-19 Tetsuo Suami New nitrosourea derivative and its preparation
JPH0323616U (sv) * 1989-07-19 1991-03-12
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
EP1235598A2 (en) * 1999-11-12 2002-09-04 Angiotech Pharmaceuticals, Inc. Compositions of a combination of radioactive therapy and cell-cycle inhibitors
KR100441764B1 (ko) * 2000-12-30 2004-07-27 한국과학기술연구원 비닐카바모일아지드 유도체
ATE420837T1 (de) † 2001-02-21 2009-01-15 Cohen Ben Z Präzisionsdosierpumpe und zubehör dafür
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
RU2695787C1 (ru) * 2018-11-07 2019-07-26 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова" Министерства здравоохранения Российской Федерации Применение соединения 2-[3-(2-хлорэтил)-3-нитрозоуреидо]-1,3-пропандиол для лечения her2-положительных опухолей в эксперименте

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2659862C3 (de) * 1976-05-25 1979-09-20 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg N-(2-Chloräthyl)-N-nitrosocarbamoylazid und Verfahren zu dessen Herstellung
DE2623420C2 (de) * 1976-05-25 1978-07-06 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Verfahren zur Herstellung unsymmetrisch 13-disubstituierter Nitrosoharnstoffe

Also Published As

Publication number Publication date
ATA373177A (de) 1980-06-15
SE453081B (sv) 1988-01-11
SU963464A3 (ru) 1982-09-30
ZA786785B (en) 1979-04-25
YU261981A (en) 1984-02-29
IL52142A0 (en) 1977-07-31
FR2372800B1 (sv) 1982-11-19
FI771665A (sv) 1977-11-26
NL187066B (nl) 1990-12-17
SE434152B (sv) 1984-07-09
IE45286L (en) 1977-11-25
DD130035A5 (de) 1978-03-01
CA1092143A (en) 1980-12-23
JPH0215533B2 (sv) 1990-04-12
BE855043A (fr) 1977-09-16
LU77389A1 (sv) 1977-09-26
ZA773144B (en) 1979-04-25
CH639947A5 (de) 1983-12-15
JPS535118A (en) 1978-01-18
US4228086A (en) 1980-10-14
HU176768B (en) 1981-05-28
DK165786C (da) 1993-06-14
MC1142A1 (fr) 1978-01-30
GB1585822A (en) 1981-03-11
NO151744B (no) 1985-02-18
JPS6317823B2 (sv) 1988-04-15
NO801626L (no) 1977-11-28
AU525278B2 (en) 1982-10-28
NO151410B (no) 1984-12-27
YU124377A (en) 1982-06-30
FR2361357A1 (fr) 1978-03-10
AT360551B (de) 1981-01-26
ES459137A1 (es) 1978-04-01
FR2372800A1 (fr) 1978-06-30
IT1085808B (it) 1985-05-28
NL7705769A (nl) 1977-11-29
DK165786B (da) 1993-01-18
DE2623420C2 (de) 1978-07-06
SE7706074L (sv) 1977-11-26
NO771804L (no) 1977-11-28
NO151410C (no) 1985-04-10
NL187066C (nl) 1991-05-16
DE2623420B1 (de) 1977-10-13
HK28882A (en) 1982-07-09
IL52142A (en) 1983-02-23
NO151744C (no) 1985-05-29
GB1585821A (en) 1981-03-11
SU973019A3 (ru) 1982-11-07
HK28782A (en) 1982-07-09
US4150146A (en) 1979-04-17
HU173579B (hu) 1979-06-28
YU41264B (en) 1986-12-31
IE45286B1 (en) 1982-07-28
FR2361357B1 (sv) 1983-03-18
DK227277A (da) 1977-11-26
YU40901B (en) 1986-08-31
JPS6226263A (ja) 1987-02-04
AU2549577A (en) 1978-11-30

Similar Documents

Publication Publication Date Title
SE8201694L (sv) Forfarande for framstellning av osymmetriskt 1,3-disubstituerade nitrosourinemnen
YU43275B (en) Process for obtaining n-(4-piperidinyl) benzamides
NO176101C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive N-(3-hydroksy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran eller dihydrobenzodioksin)karboksamidderivater
ES8107167A1 (es) Un procedimiento para preparar hidrazonas de benzofenona.
NO741580L (no) Analogifremgangsmåte for fremstilling av fysiologisk aktive acylaminosyreamider
IE36383L (en) Aryl guanidines
GB1425354A (en) Indole derivatives
ES8106887A1 (es) Procedimiento para la obtencion de uretanos n,o-disustitui- dos
IE41652L (en) Amines having cardiac activity
US3108098A (en) Novel nu-morpholinesulfonyl ureas
EP0301718A3 (en) Process for preparing novel diamines
IE39655B1 (en) Polyamide concentrates containing sulphonate groups
IE37514L (en) 1,5-benzodiazepines.
EP0307669A3 (de) Verfahren zur Herstellung von Amminsalzen des Aluminiumjodids
DE3278075D1 (de) New n-nitroso-n-(beta-chloro-ethyl)-carbamoyl peptides
SU354725A1 (ru) Способ получени хлоргидрата 3-/бис(2-оксиэтил) амино/-трицикло /4,3,1,1 /ундекана
IE791818L (en) Endoparasiticidal paste
AU5442580A (en) Amino acid derivatives of 2,3 dioxopiperazine
SU979339A1 (ru) Способ получени 2-амино-3,4-дициано-1,5-замещенных пирролов
ES550039A0 (es) Procedimiento para preparar n-(-(1&#39;-alil-2&#39;-pirrolidinil)- metil)-2-metoxi-4,5-azimido-benzamida a escala industrial
ES8107191A1 (es) Procedimiento para la preparacion de 2-(2-cloro-4-ciclopro- pil-fenil-imino)-imidazolidina
JPS5246027A (en) Process for preparation of thiolcarbamates
IE36412B1 (en) Herbicides
SU514838A1 (ru) Способ получени триорганил (/2-аминоэтилтио/-алкил) силанов
NO881812L (no) Fremgangsmaate for fremstilling av krystallinsk n-(s-3-metyl-heptanoyl)-d-gamma-glutamyl-glycyl-d-alanin og mellomprodukter for fremstillingen.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8201694-0

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8201694-0

Format of ref document f/p: F