IL52142A - Process for the preparation of unsymmetrically 1,3-disubstituted nitrosourea and some such novel compounds - Google Patents

Process for the preparation of unsymmetrically 1,3-disubstituted nitrosourea and some such novel compounds

Info

Publication number
IL52142A
IL52142A IL52142A IL5214277A IL52142A IL 52142 A IL52142 A IL 52142A IL 52142 A IL52142 A IL 52142A IL 5214277 A IL5214277 A IL 5214277A IL 52142 A IL52142 A IL 52142A
Authority
IL
Israel
Prior art keywords
unsymmetrically
nitrosourea
disubstituted
preparation
novel compounds
Prior art date
Application number
IL52142A
Other languages
English (en)
Other versions
IL52142A0 (en
Inventor
Gerhard Eisenbrand
Original Assignee
Deutsches Krebsforsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch
Publication of IL52142A0 publication Critical patent/IL52142A0/xx
Publication of IL52142A publication Critical patent/IL52142A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL52142A 1976-05-25 1977-05-22 Process for the preparation of unsymmetrically 1,3-disubstituted nitrosourea and some such novel compounds IL52142A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2623420A DE2623420C2 (de) 1976-05-25 1976-05-25 Verfahren zur Herstellung unsymmetrisch 13-disubstituierter Nitrosoharnstoffe

Publications (2)

Publication Number Publication Date
IL52142A0 IL52142A0 (en) 1977-07-31
IL52142A true IL52142A (en) 1983-02-23

Family

ID=5978961

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52142A IL52142A (en) 1976-05-25 1977-05-22 Process for the preparation of unsymmetrically 1,3-disubstituted nitrosourea and some such novel compounds

Country Status (27)

Country Link
US (2) US4150146A (sv)
JP (2) JPS535118A (sv)
AT (1) AT360551B (sv)
AU (1) AU525278B2 (sv)
BE (1) BE855043A (sv)
CA (1) CA1092143A (sv)
CH (1) CH639947A5 (sv)
DD (1) DD130035A5 (sv)
DE (1) DE2623420C2 (sv)
DK (1) DK165786C (sv)
ES (1) ES459137A1 (sv)
FI (1) FI771665A (sv)
FR (2) FR2361357A1 (sv)
GB (2) GB1585822A (sv)
HK (2) HK28782A (sv)
HU (2) HU176768B (sv)
IE (1) IE45286B1 (sv)
IL (1) IL52142A (sv)
IT (1) IT1085808B (sv)
LU (1) LU77389A1 (sv)
MC (1) MC1142A1 (sv)
NL (1) NL187066C (sv)
NO (2) NO151410C (sv)
SE (2) SE434152B (sv)
SU (2) SU963464A3 (sv)
YU (2) YU40901B (sv)
ZA (2) ZA786785B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2623420C2 (de) * 1976-05-25 1978-07-06 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Verfahren zur Herstellung unsymmetrisch 13-disubstituierter Nitrosoharnstoffe
DE2845574A1 (de) 1978-10-19 1980-04-24 Deutsches Krebsforsch Durch heterocyclische ringe oder alkylreste substituierte analoga von ccnu und verfahren zu deren herstellung
JPS57116043A (en) * 1981-01-12 1982-07-19 Tetsuo Suami New nitrosourea derivative and its preparation
JPH0323616U (sv) * 1989-07-19 1991-03-12
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CA2388844A1 (en) * 1999-11-12 2001-05-25 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
KR100441764B1 (ko) * 2000-12-30 2004-07-27 한국과학기술연구원 비닐카바모일아지드 유도체
ATE420837T1 (de) 2001-02-21 2009-01-15 Cohen Ben Z Präzisionsdosierpumpe und zubehör dafür
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
RU2695787C1 (ru) * 2018-11-07 2019-07-26 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Петрова" Министерства здравоохранения Российской Федерации Применение соединения 2-[3-(2-хлорэтил)-3-нитрозоуреидо]-1,3-пропандиол для лечения her2-положительных опухолей в эксперименте

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2659862C3 (de) * 1976-05-25 1979-09-20 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg N-(2-Chloräthyl)-N-nitrosocarbamoylazid und Verfahren zu dessen Herstellung
DE2623420C2 (de) * 1976-05-25 1978-07-06 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Verfahren zur Herstellung unsymmetrisch 13-disubstituierter Nitrosoharnstoffe

Also Published As

Publication number Publication date
JPH0215533B2 (sv) 1990-04-12
FI771665A (sv) 1977-11-26
YU124377A (en) 1982-06-30
AU525278B2 (en) 1982-10-28
LU77389A1 (sv) 1977-09-26
DE2623420B1 (de) 1977-10-13
FR2361357B1 (sv) 1983-03-18
YU40901B (en) 1986-08-31
SE7706074L (sv) 1977-11-26
ES459137A1 (es) 1978-04-01
NL187066B (nl) 1990-12-17
HK28782A (en) 1982-07-09
DK165786B (da) 1993-01-18
DE2623420C2 (de) 1978-07-06
SE8201694L (sv) 1982-03-17
IL52142A0 (en) 1977-07-31
FR2361357A1 (fr) 1978-03-10
YU261981A (en) 1984-02-29
SE453081B (sv) 1988-01-11
SU963464A3 (ru) 1982-09-30
SU973019A3 (ru) 1982-11-07
CH639947A5 (de) 1983-12-15
DK227277A (da) 1977-11-26
DK165786C (da) 1993-06-14
JPS535118A (en) 1978-01-18
NO151744B (no) 1985-02-18
JPS6317823B2 (sv) 1988-04-15
BE855043A (fr) 1977-09-16
HU176768B (en) 1981-05-28
NL7705769A (nl) 1977-11-29
DD130035A5 (de) 1978-03-01
AT360551B (de) 1981-01-26
IE45286L (en) 1977-11-25
ZA786785B (en) 1979-04-25
SE434152B (sv) 1984-07-09
NL187066C (nl) 1991-05-16
YU41264B (en) 1986-12-31
JPS6226263A (ja) 1987-02-04
NO771804L (no) 1977-11-28
NO801626L (no) 1977-11-28
IT1085808B (it) 1985-05-28
CA1092143A (en) 1980-12-23
NO151744C (no) 1985-05-29
ZA773144B (en) 1979-04-25
HU173579B (hu) 1979-06-28
GB1585821A (en) 1981-03-11
NO151410C (no) 1985-04-10
FR2372800A1 (fr) 1978-06-30
AU2549577A (en) 1978-11-30
ATA373177A (de) 1980-06-15
MC1142A1 (fr) 1978-01-30
NO151410B (no) 1984-12-27
FR2372800B1 (sv) 1982-11-19
HK28882A (en) 1982-07-09
IE45286B1 (en) 1982-07-28
US4150146A (en) 1979-04-17
GB1585822A (en) 1981-03-11
US4228086A (en) 1980-10-14

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