SE8200647L - Pyrrolidin-derivat - Google Patents
Pyrrolidin-derivatInfo
- Publication number
- SE8200647L SE8200647L SE8200647A SE8200647A SE8200647L SE 8200647 L SE8200647 L SE 8200647L SE 8200647 A SE8200647 A SE 8200647A SE 8200647 A SE8200647 A SE 8200647A SE 8200647 L SE8200647 L SE 8200647L
- Authority
- SE
- Sweden
- Prior art keywords
- hydroxy
- compound
- formula
- pyrrolidine derivatives
- methoxybenzoyl
- Prior art date
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- VUOZPAGAAMBEGM-UHFFFAOYSA-N 3-hydroxy-1-(3-hydroxy-4-methoxybenzoyl)pyrrolidin-2-one Chemical compound C1=C(O)C(OC)=CC=C1C(=O)N1C(=O)C(O)CC1 VUOZPAGAAMBEGM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH77081A CH646149A5 (de) | 1981-02-05 | 1981-02-05 | Pyrrolidin-derivat. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8200647L true SE8200647L (sv) | 1982-08-06 |
Family
ID=4194769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8200647A SE8200647L (sv) | 1981-02-05 | 1982-02-04 | Pyrrolidin-derivat |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US4452807A (it) |
| EP (1) | EP0057846B1 (it) |
| JP (1) | JPS57146753A (it) |
| KR (1) | KR830009023A (it) |
| AR (1) | AR231127A1 (it) |
| AT (2) | ATE13668T1 (it) |
| AU (1) | AU552063B2 (it) |
| BG (1) | BG36932A3 (it) |
| BR (1) | BR8200615A (it) |
| CA (1) | CA1158250A (it) |
| CH (1) | CH646149A5 (it) |
| CS (1) | CS227035B2 (it) |
| DD (1) | DD202539A5 (it) |
| DE (2) | DE3202281A1 (it) |
| DK (1) | DK20682A (it) |
| ES (1) | ES509312A0 (it) |
| FI (1) | FI820192L (it) |
| FR (1) | FR2499075A1 (it) |
| GB (1) | GB2092584B (it) |
| GR (1) | GR76052B (it) |
| HU (1) | HU184988B (it) |
| IE (1) | IE52439B1 (it) |
| IL (1) | IL64896A (it) |
| IS (1) | IS2700A7 (it) |
| IT (1) | IT1153402B (it) |
| LU (1) | LU83923A1 (it) |
| MC (1) | MC1440A1 (it) |
| NL (1) | NL8200337A (it) |
| NO (1) | NO820346L (it) |
| NZ (1) | NZ199624A (it) |
| OA (1) | OA07002A (it) |
| PH (1) | PH18267A (it) |
| PL (1) | PL135221B1 (it) |
| PT (1) | PT74387B (it) |
| RO (1) | RO83099B (it) |
| SE (1) | SE8200647L (it) |
| SU (1) | SU1143315A3 (it) |
| YU (1) | YU23982A (it) |
| ZA (1) | ZA82608B (it) |
| ZW (1) | ZW1982A1 (it) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| FR2551751B1 (fr) * | 1983-09-12 | 1986-04-25 | Serobiologiques Lab Sa | Nouveau procede de preparation d'un derive pyroglutamique, nouveaux derives pyroglutamiques, nouveaux intermediaires de synthese de preparation de ceux-ci et utilisation ou application des derives pyroglutamiques comme agents antibacteriens ou antifongiques |
| DE3336024A1 (de) * | 1983-10-04 | 1985-04-18 | Boehringer Ingelheim KG, 6507 Ingelheim | 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
| DE3632589A1 (de) * | 1985-10-18 | 1987-04-23 | Bayer Ag | Verfahren zur herstellung von (gamma)-butyrolactamen |
| DE3537075A1 (de) * | 1985-10-18 | 1987-04-23 | Bayer Ag | Verfahren zur herstellung von clausenamid |
| US4677114A (en) * | 1985-11-22 | 1987-06-30 | Warner-Lambert Company | Pyrrolidone-2 derivatives and pharmaceutical compositions thereof |
| IT1215587B (it) * | 1987-06-26 | 1990-02-14 | Roussel Maestretti Spa | Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale. |
| JPH0720930B2 (ja) * | 1988-07-09 | 1995-03-08 | 明治製菓株式会社 | ピロリジノン化合物及び脳機能障害改善剤 |
| US5049577A (en) * | 1990-01-29 | 1991-09-17 | E. R. Squibb & Sons, Inc. | 2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith |
| US5049578A (en) * | 1990-03-09 | 1991-09-17 | E. R. Squibb & Sons, Inc. | 1-aroyl or 1-acyl-2-2pyrrolidinyl-3,5-dihydroxy alkanoic and alkenoic acids, salts, esters and lactones |
| DK0651746T3 (da) * | 1992-07-24 | 2002-07-29 | Univ California | Lægemidler, der forbedrer synaptiske responser medieret af AMPA-receptorer |
| US5852008A (en) * | 1995-01-24 | 1998-12-22 | The Regents Of The University Of California | Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES433723A1 (es) * | 1975-01-10 | 1976-11-16 | Lafarquim S A Lab | Procedimiento de obtencion de un derivado de 2-pirrolidi- nona. |
| IT1045043B (it) * | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
| CU21107A3 (es) * | 1978-02-10 | 1988-02-01 | Hoffmann La Roche | Pyrrolidines derivatives |
| CA1115212A (en) * | 1978-02-10 | 1981-12-29 | Emilio Kyburz | Pyrrolidine derivatives |
| CA1124247A (en) * | 1979-08-09 | 1982-05-25 | Hoffmann-La Roche Limited | Pyrrolidine derivatives |
-
1981
- 1981-02-05 CH CH77081A patent/CH646149A5/de not_active IP Right Cessation
-
1982
- 1982-01-08 CA CA000393829A patent/CA1158250A/en not_active Expired
- 1982-01-14 IT IT19115/82A patent/IT1153402B/it active
- 1982-01-18 DK DK20682A patent/DK20682A/da not_active Application Discontinuation
- 1982-01-20 US US06/340,920 patent/US4452807A/en not_active Expired - Fee Related
- 1982-01-21 FI FI820192A patent/FI820192L/fi not_active Application Discontinuation
- 1982-01-25 DE DE19823202281 patent/DE3202281A1/de not_active Withdrawn
- 1982-01-25 EP EP82100494A patent/EP0057846B1/de not_active Expired
- 1982-01-25 AT AT82100494T patent/ATE13668T1/de not_active IP Right Cessation
- 1982-01-25 DE DE8282100494T patent/DE3263960D1/de not_active Expired
- 1982-01-28 OA OA57598A patent/OA07002A/xx unknown
- 1982-01-29 NL NL8200337A patent/NL8200337A/nl not_active Application Discontinuation
- 1982-01-29 IL IL64896A patent/IL64896A/xx unknown
- 1982-01-29 ZA ZA82608A patent/ZA82608B/xx unknown
- 1982-01-29 ZW ZW19/82A patent/ZW1982A1/xx unknown
- 1982-01-29 CS CS82629A patent/CS227035B2/cs unknown
- 1982-01-29 PH PH26797A patent/PH18267A/en unknown
- 1982-01-30 RO RO106487A patent/RO83099B/ro unknown
- 1982-02-01 HU HU82285A patent/HU184988B/hu unknown
- 1982-02-01 NZ NZ199624A patent/NZ199624A/en unknown
- 1982-02-02 AU AU80104/82A patent/AU552063B2/en not_active Ceased
- 1982-02-02 JP JP57014411A patent/JPS57146753A/ja active Granted
- 1982-02-02 AR AR288323A patent/AR231127A1/es active
- 1982-02-03 DD DD82237159A patent/DD202539A5/de not_active IP Right Cessation
- 1982-02-03 GR GR67187A patent/GR76052B/el unknown
- 1982-02-03 MC MC821572A patent/MC1440A1/xx unknown
- 1982-02-03 SU SU823381951A patent/SU1143315A3/ru active
- 1982-02-03 FR FR8201714A patent/FR2499075A1/fr not_active Withdrawn
- 1982-02-04 BR BR8200615A patent/BR8200615A/pt unknown
- 1982-02-04 AT AT0041882A patent/AT377982B/de not_active IP Right Cessation
- 1982-02-04 NO NO820346A patent/NO820346L/no unknown
- 1982-02-04 GB GB8203264A patent/GB2092584B/en not_active Expired
- 1982-02-04 IE IE249/82A patent/IE52439B1/en unknown
- 1982-02-04 LU LU83923A patent/LU83923A1/de unknown
- 1982-02-04 SE SE8200647A patent/SE8200647L/xx not_active Application Discontinuation
- 1982-02-04 ES ES509312A patent/ES509312A0/es active Granted
- 1982-02-04 KR KR1019820000475A patent/KR830009023A/ko unknown
- 1982-02-04 PT PT74387A patent/PT74387B/pt unknown
- 1982-02-04 IS IS2700A patent/IS2700A7/is unknown
- 1982-02-04 YU YU00239/82A patent/YU23982A/xx unknown
- 1982-02-05 BG BG8255269A patent/BG36932A3/xx unknown
- 1982-02-05 PL PL1982234962A patent/PL135221B1/pl unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8200647-9 |