RO83099A - Procedeu pentru prepararea unui pirolidinone - Google Patents

Procedeu pentru prepararea unui pirolidinone

Info

Publication number
RO83099A
RO83099A RO82106487A RO10648782A RO83099A RO 83099 A RO83099 A RO 83099A RO 82106487 A RO82106487 A RO 82106487A RO 10648782 A RO10648782 A RO 10648782A RO 83099 A RO83099 A RO 83099A
Authority
RO
Romania
Prior art keywords
pyrrolidinone
preparation
Prior art date
Application number
RO82106487A
Other languages
English (en)
French (fr)
Other versions
RO83099B (ro
Inventor
Werner Aschwanden
Emilio Kyburz
Original Assignee
F.Hoffmann La Roche Ag,Ch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann La Roche Ag,Ch filed Critical F.Hoffmann La Roche Ag,Ch
Publication of RO83099A publication Critical patent/RO83099A/ro
Publication of RO83099B publication Critical patent/RO83099B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
RO106487A 1981-02-05 1982-01-30 Procedeu pentru prepararea unei pirolidinone RO83099B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH77081A CH646149A5 (de) 1981-02-05 1981-02-05 Pyrrolidin-derivat.

Publications (2)

Publication Number Publication Date
RO83099A true RO83099A (ro) 1984-02-21
RO83099B RO83099B (ro) 1984-02-28

Family

ID=4194769

Family Applications (1)

Application Number Title Priority Date Filing Date
RO106487A RO83099B (ro) 1981-02-05 1982-01-30 Procedeu pentru prepararea unei pirolidinone

Country Status (40)

Country Link
US (1) US4452807A (ro)
EP (1) EP0057846B1 (ro)
JP (1) JPS57146753A (ro)
KR (1) KR830009023A (ro)
AR (1) AR231127A1 (ro)
AT (2) ATE13668T1 (ro)
AU (1) AU552063B2 (ro)
BG (1) BG36932A3 (ro)
BR (1) BR8200615A (ro)
CA (1) CA1158250A (ro)
CH (1) CH646149A5 (ro)
CS (1) CS227035B2 (ro)
DD (1) DD202539A5 (ro)
DE (2) DE3263960D1 (ro)
DK (1) DK20682A (ro)
ES (1) ES8304545A1 (ro)
FI (1) FI820192L (ro)
FR (1) FR2499075A1 (ro)
GB (1) GB2092584B (ro)
GR (1) GR76052B (ro)
HU (1) HU184988B (ro)
IE (1) IE52439B1 (ro)
IL (1) IL64896A (ro)
IS (1) IS2700A7 (ro)
IT (1) IT1153402B (ro)
LU (1) LU83923A1 (ro)
MC (1) MC1440A1 (ro)
NL (1) NL8200337A (ro)
NO (1) NO820346L (ro)
NZ (1) NZ199624A (ro)
OA (1) OA07002A (ro)
PH (1) PH18267A (ro)
PL (1) PL135221B1 (ro)
PT (1) PT74387B (ro)
RO (1) RO83099B (ro)
SE (1) SE8200647L (ro)
SU (1) SU1143315A3 (ro)
YU (1) YU23982A (ro)
ZA (1) ZA82608B (ro)
ZW (1) ZW1982A1 (ro)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
FR2551751B1 (fr) * 1983-09-12 1986-04-25 Serobiologiques Lab Sa Nouveau procede de preparation d'un derive pyroglutamique, nouveaux derives pyroglutamiques, nouveaux intermediaires de synthese de preparation de ceux-ci et utilisation ou application des derives pyroglutamiques comme agents antibacteriens ou antifongiques
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3632589A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von (gamma)-butyrolactamen
DE3537075A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von clausenamid
US4677114A (en) * 1985-11-22 1987-06-30 Warner-Lambert Company Pyrrolidone-2 derivatives and pharmaceutical compositions thereof
IT1215587B (it) * 1987-06-26 1990-02-14 Roussel Maestretti Spa Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.
JPH0720930B2 (ja) * 1988-07-09 1995-03-08 明治製菓株式会社 ピロリジノン化合物及び脳機能障害改善剤
US5049577A (en) * 1990-01-29 1991-09-17 E. R. Squibb & Sons, Inc. 2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith
US5049578A (en) * 1990-03-09 1991-09-17 E. R. Squibb & Sons, Inc. 1-aroyl or 1-acyl-2-2pyrrolidinyl-3,5-dihydroxy alkanoic and alkenoic acids, salts, esters and lactones
ATE253909T1 (de) * 1992-07-24 2003-11-15 Univ California Arzneimittel die den durch ampa rezeptoren vermittelten synaptischen response erhöhen
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES433723A1 (es) * 1975-01-10 1976-11-16 Lafarquim S A Lab Procedimiento de obtencion de un derivado de 2-pirrolidi- nona.
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
CA1115212A (en) * 1978-02-10 1981-12-29 Emilio Kyburz Pyrrolidine derivatives
NL8004025A (nl) * 1979-08-09 1981-02-11 Hoffmann La Roche Pyrrolidinederivaten en werkwijze voor het bereiden daarvan alsmede geneesmiddel.

Also Published As

Publication number Publication date
AT377982B (de) 1985-05-28
NO820346L (no) 1982-08-06
PH18267A (en) 1985-05-14
ES509312A0 (es) 1983-03-16
GB2092584B (en) 1984-08-01
ES8304545A1 (es) 1983-03-16
IL64896A (en) 1985-07-31
GR76052B (ro) 1984-08-03
US4452807A (en) 1984-06-05
IE820249L (en) 1982-08-05
HU184988B (en) 1984-11-28
SE8200647L (sv) 1982-08-06
NL8200337A (nl) 1982-09-01
FR2499075A1 (fr) 1982-08-06
ZW1982A1 (en) 1982-09-01
PT74387A (en) 1982-03-01
PT74387B (en) 1984-10-22
IL64896A0 (en) 1982-03-31
DE3263960D1 (en) 1985-07-11
IE52439B1 (en) 1987-10-28
AU552063B2 (en) 1986-05-22
ATA41882A (de) 1984-10-15
BG36932A3 (en) 1985-02-15
PL135221B1 (en) 1985-10-31
CA1158250A (en) 1983-12-06
EP0057846B1 (de) 1985-06-05
JPS57146753A (en) 1982-09-10
CS227035B2 (en) 1984-04-16
YU23982A (en) 1985-03-20
AU8010482A (en) 1982-08-12
CH646149A5 (de) 1984-11-15
SU1143315A3 (ru) 1985-02-28
IT8219115A0 (it) 1982-01-14
OA07002A (fr) 1983-08-31
IT1153402B (it) 1987-01-14
KR830009023A (ko) 1983-12-17
DD202539A5 (de) 1983-09-21
IS2700A7 (is) 1982-08-06
EP0057846A1 (de) 1982-08-18
LU83923A1 (de) 1983-09-02
DE3202281A1 (de) 1982-09-16
ZA82608B (en) 1982-12-29
ATE13668T1 (de) 1985-06-15
NZ199624A (en) 1984-12-14
JPH0354097B2 (ro) 1991-08-19
FI820192L (fi) 1982-08-06
DK20682A (da) 1982-08-06
GB2092584A (en) 1982-08-18
RO83099B (ro) 1984-02-28
PL234962A1 (ro) 1982-09-27
BR8200615A (pt) 1982-12-14
AR231127A1 (es) 1984-09-28
MC1440A1 (fr) 1982-12-06

Similar Documents

Publication Publication Date Title
RO88641A (ro) Procedeu pentru prepararea etilenglicolului
FR2603899B1 (fr) Procede perfectionne pour l'expression de recombinants
RO86859A (ro) Procedeu pentru prepararea unui bisester al metandiolului
PT75499A (fr) Procede pour la preparation de l'alkanoilanilides
FR2572094B1 (fr) Procede pour la preparation continue de l'ethanol
RO91262A (ro) Procedeu pentru prepararea stearatului de acetileritromicina
RO83099A (ro) Procedeu pentru prepararea unui pirolidinone
BE892808A (fr) Procede pour la decomposition d'alkyl-tert-alkyl-ethers
PT75209B (fr) Procede de preparation d'amidobenzamides
RO92200A (ro) Procedeu pentru prepararea unor s-benzilcarbamati
FR2503158B1 (fr) Procede pour la preparation de dithiazolyldisulfures
RO76936A (ro) Procedeu pentru prepararea de p-fenilendiamine asimetrice n-fenil-n'-substituite
RO82949A (ro) Procedeu pentru prepararea unui derivat de fenilpropargilamina
RO85812A (ro) Procedeu pentru prepararea de derivati de azolilpentina
RO89437A (ro) Procedeu pentru prepararea unei forme galenice de sulpirida
RO81640A (ro) Procedeu de preparare a insulinei
PT72457B (fr) Procede pour la preparation d'une composition pesticide conte- nant esteres de trifluormethylbenzyl
FR2514785B1 (fr) Procede pour l'affinage de ferrochrome
FR2549042B1 (fr) Procede pour la preparation de la 3,11-dimethyl-2-nonacosanone
RO85313A (ro) Procedeu pentru prepararea unor anilide ale ergolinei
BE895023A (fr) Procede pour l'execution d'un tube composite
FR2499987B1 (fr) Procede pour la preparation de composes de o-indol-3-yl-alkanol
FR2508447B1 (fr) Procede pour la preparation de la cimetidine
MA19649A1 (fr) Procede de preparation d'haloalkyl-8-4h (1)-benzopyran-4-ones
FR2510876B1 (fr) Procede de preparation d'un additif pour fourrage