SE7908642L - Fluor-prostaglandiner - Google Patents
Fluor-prostaglandinerInfo
- Publication number
- SE7908642L SE7908642L SE7908642A SE7908642A SE7908642L SE 7908642 L SE7908642 L SE 7908642L SE 7908642 A SE7908642 A SE 7908642A SE 7908642 A SE7908642 A SE 7908642A SE 7908642 L SE7908642 L SE 7908642L
- Authority
- SE
- Sweden
- Prior art keywords
- ndr
- hydroxy
- trans
- symbol
- methyl
- Prior art date
Links
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000004043 oxo group Chemical group O=* 0.000 claims 2
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- RYXPMWYHEBGTRV-UHFFFAOYSA-N Omeprazole sodium Chemical compound [Na+].N=1C2=CC(OC)=CC=C2[N-]C=1S(=O)CC1=NC=C(C)C(OC)=C1C RYXPMWYHEBGTRV-UHFFFAOYSA-N 0.000 claims 1
- 239000004015 abortifacient agent Substances 0.000 claims 1
- 231100000641 abortifacient agent Toxicity 0.000 claims 1
- 125000004423 acyloxy group Chemical group 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 230000003529 luteolytic effect Effects 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000004953 trihalomethyl group Chemical group 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (1)
1. Optiskt aktiv eller racemisk fluor-prostaglandinfOrening till anvindning son luteolytiskt och abortivt Nadel, k 0nnetecknat at-ay, att den har formeln (I) (I) vilken R Or vate, en C1-C 12-alkylgrupp eller en katjon av en farmaceutiskt accepP■kel bas;- - - representerar en enkel- eller dubbe.Ining, I vilkner symbolen - --- Or en dubbelbindning, 03 Or en vdteatom seat 01 och R2 bildar tillsammans en oxogrupp, medan, ndr symbolen -- - - Or en enkelbindning, R3 Or hydroxi sant den one av 01 och 02 Or \rate och den andra Or hydroxi eller acyloxi eller Ri och R2 bildar tillsannans en oxogrupp; A Or trans-CH=CH- eller -CC-; den ena av 06 och 123 Or hydroxi och den. andra Or vdte; 06 Or vote, metyl eller fluor; n Or noll eller Ott heltal av 1-6; 07 Or, ndr A Or trans-CE=CO-, en cykloalkylgrupp med 3-7 ringkolatomer, medan, ndr A Or -C=C-, R7 Or metyl, cykloalkyl med 3-7 ringkolatomer eller fenyl, osubstituerad eller valfritt substituerad med en eller flera substituenter valda bland halogen, C1-C6-alkoxi och trihalogenmetyl. F s R'A.— „c-(cH ) —R .R3C t2 n 7 RI ;:i R6 4
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21493/75A IT1049373B (it) | 1975-03-21 | 1975-03-21 | Fluoro prostaglandine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7908642L true SE7908642L (sv) | 1979-10-18 |
| SE431090B SE431090B (sv) | 1984-01-16 |
Family
ID=11182621
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7603431A SE427109B (sv) | 1975-03-21 | 1976-03-19 | Forfarande for framstellning av 16-fluorsubstituerade prostaglandinderivat |
| SE7908642A SE431090B (sv) | 1975-03-21 | 1979-10-18 | Optiskt aktiv eller racemisk fluor-prostaglandinforening till anvendning som luteolytiskt och abortivt medel |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7603431A SE427109B (sv) | 1975-03-21 | 1976-03-19 | Forfarande for framstellning av 16-fluorsubstituerade prostaglandinderivat |
Country Status (13)
| Country | Link |
|---|---|
| JP (2) | JPS5921864B2 (sv) |
| CS (1) | CS191296B2 (sv) |
| CY (1) | CY956A (sv) |
| DK (1) | DK146593C (sv) |
| HK (1) | HK44978A (sv) |
| HU (1) | HU175729B (sv) |
| IL (1) | IL49208A (sv) |
| IT (1) | IT1049373B (sv) |
| KE (1) | KE2859A (sv) |
| MY (1) | MY7800358A (sv) |
| SE (2) | SE427109B (sv) |
| SU (1) | SU710516A3 (sv) |
| ZA (1) | ZA761611B (sv) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0136589B1 (en) * | 1983-09-07 | 1988-03-09 | Indiana University Foundation | 12, 16-difluoroprostaglandin f2 alpha compounds |
| JPS60229814A (ja) * | 1984-04-27 | 1985-11-15 | Iseki & Co Ltd | 小型車輛における車輪の上下装置 |
| JPS62196619U (sv) * | 1986-06-02 | 1987-12-14 | ||
| EP0591532A4 (en) * | 1991-04-22 | 1994-11-09 | Taisho Pharmaceutical Co Ltd | PROSTAGLANDIN E1 ANALOG. |
-
1975
- 1975-03-21 IT IT21493/75A patent/IT1049373B/it active
-
1976
- 1976-03-12 IL IL49208A patent/IL49208A/xx unknown
- 1976-03-16 ZA ZA761611A patent/ZA761611B/xx unknown
- 1976-03-17 DK DK116676A patent/DK146593C/da not_active IP Right Cessation
- 1976-03-17 CS CS761740A patent/CS191296B2/cs unknown
- 1976-03-18 CY CY956A patent/CY956A/xx unknown
- 1976-03-19 SU SU762336447A patent/SU710516A3/ru active
- 1976-03-19 SE SE7603431A patent/SE427109B/sv not_active IP Right Cessation
- 1976-03-19 HU HU76EA158A patent/HU175729B/hu unknown
- 1976-03-22 JP JP51031179A patent/JPS5921864B2/ja not_active Expired
-
1978
- 1978-06-18 KE KE2859A patent/KE2859A/xx unknown
- 1978-08-10 HK HK449/78A patent/HK44978A/xx unknown
- 1978-12-30 MY MY358/78A patent/MY7800358A/xx unknown
-
1979
- 1979-10-18 SE SE7908642A patent/SE431090B/sv not_active IP Right Cessation
-
1984
- 1984-01-18 JP JP59005843A patent/JPS6033826B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL49208A0 (en) | 1976-05-31 |
| HU175729B (hu) | 1980-10-28 |
| DK146593C (da) | 1984-04-30 |
| DK146593B (da) | 1983-11-14 |
| CS191296B2 (en) | 1979-06-29 |
| MY7800358A (en) | 1978-12-31 |
| IT1049373B (it) | 1981-01-20 |
| SU710516A3 (ru) | 1980-01-15 |
| IL49208A (en) | 1980-10-26 |
| KE2859A (en) | 1978-08-04 |
| DK116676A (da) | 1976-09-22 |
| SE7603431L (sv) | 1976-09-22 |
| SE427109B (sv) | 1983-03-07 |
| JPS6033826B2 (ja) | 1985-08-05 |
| JPS51118747A (en) | 1976-10-18 |
| JPS59144753A (ja) | 1984-08-18 |
| JPS5921864B2 (ja) | 1984-05-22 |
| HK44978A (en) | 1978-08-18 |
| ZA761611B (en) | 1977-03-30 |
| CY956A (en) | 1978-12-22 |
| SE431090B (sv) | 1984-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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